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MSRLGDDDQPSMSSLSGESPRKPHFYGIARVIRRASIPIILSWIALAAFLNISVPQLEEVGKQRSVSMSP DDAPAVISMEHIGEVFEEYESNSSVMIVLEGEQPLGDDTRRYYADLISGLEADTTHVEHVQDLWSDPLTA AGAQSADGKSTYFQVYLAGNQGEALANESVRAVQELVAESQPPAGVKAFVTGASALAAEQEEAGHTSMRF VEALTFLVITIMLVLFFRSIVTTLLILVMVGLSLMTVRGAVAFLGFHDIIGLSTFATSLLVTLAIAIAVD YAIFLVGRYQEAKGKGATAEEAYFTMFGGNAHVIVGSGLTIAGATFCLSFTRLPYFQSLGVPLALGMLVL IAVAMTFGPAMVTIASKFGLLEPKRAMRVRGWRKIGAVTVRWPGAILVASVAVSLIGLLALPGYQTSYND RNYLPDDIQSNVGYAAAERHFSPARLNPEVLMVETDHDLRNPADFIVIEKIAKALFTVEGIGRVQTITRP DGTPIESTSIPYIMSRQSTTQQLNEKYMLDRMDDMQVQAESLQTTIDTMEKMQALMSQMSEITNSMVAKT KTMAVDITELRDHIADLDDFVRPIRNYFYWEPHCYNIPVCHSMRSLFDLIDGTNLLTDNVQDLVPDLERM AAIMPELIALMPQQIETMKSQREMMLTQFQTQKGQLEAAAEMQVDAGAMGDAFNDAWNADSFYLPPEAFE NADFQSGIEQFISPNGHAVRFIIAHEGDPLSPAGVEKIDKLKTAAKEAVKGTPLEGSKIYLGGTAATFKD MADGTRYDLLIAGIAAVGLIFIIMLILTRAIVAAAVIVGTVVLSLGASFGLSVLVWQHLVGIELHWMVLP MAVIILLAVGADYNLLVVSRLKEEVGAGLHTGLIRTMGGSGSVVTAAGMVFALTMMTMAVSDLTIIGQVG TTIGMGLIFDTLVIRSFMTPSIAALLGRWFWWPQQIRTRPAPSPWPAPPARVADDTGR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1614 | - | - | 100% (968) | transport protein |
M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 69.21% (945) | transport protein |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 63.99% (922) | transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0695c | mmpL5 | 0.0 | 65.77% (932) | transmembrane transport protein MmpL5 |
M. gilvum PYR-GCK | Mflv_4825 | - | 0.0 | 89.85% (946) | transport protein |
M. tuberculosis H37Rv | Rv0676c | mmpL5 | 0.0 | 65.77% (932) | transmembrane transport protein MmpL5 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 56.52% (943) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4382c | - | 0.0 | 62.02% (932) | putative membrane protein, MmpL |
M. marinum M | MMAR_1005 | mmpL5 | 0.0 | 64.50% (952) | transmembrane transport protein, MmpL5 |
M. avium 104 | MAV_2510 | - | 0.0 | 64.39% (935) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_0225 | - | 0.0 | 67.45% (940) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 67.37% (944) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 64.39% (952) | transmembrane transport protein, MmpL5 |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_1614|M.vanbaalenii_PYR-1 ---------MSRLGDD----DQPSMSSLSGESPR--KPHFYGIARVIRRA Mflv_4825|M.gilvum_PYR-GCK MCRRATGSAITTFGRNNFGFNNFGLNAVEDRTVHGDKPHFYGIARVIRAA TH_3260|M.thermoresistible__bu --------MTANPGHVR---TDEAPTDRLDIKVSTHGPSF--ISTWIRRL MSMEG_0225|M.smegmatis_MC2_155 ---------MSTPDAP----TEAIPSAHGKYTNHG------GIAKLIRTL MAB_4382c|M.abscessus_ATCC_199 ---------MSKPMNDP--TTDAFPAARHAARPW--------LPRMIRVL Mb0695c|M.bovis_AF2122/97 --------MIVQRTAAP---TGSVPPDRHAARPF--------IPRMIRTF Rv0676c|M.tuberculosis_H37Rv --------MIVQRTAAP---TGSVPPDRHAARPF--------IPRMIRTF MMAR_1005|M.marinum_M --------MTATTTDTP---TDVVPPAEHPPRPF--------IPRMIRTF MUL_0757|M.ulcerans_Agy99 --------MTATTTDTP---TDVVPPAEHPPRPF--------IPRMIRTF MAV_2510|M.avium_104 --------MSTTFDDTR---TDAIPVVKEPVREK--------IPRFIRAF MLBr_02378|M.leprae_Br4923 --------MTVKCANDL---------DTHTKPPF--------VARMIHRF :. *: Mvan_1614|M.vanbaalenii_PYR-1 SIPIILSWIALAAFLNISVPQLEEVGKQRSVSMSPDDAPAVISMEHIGEV Mflv_4825|M.gilvum_PYR-GCK SIPIILIWVAIAAFLNVSVPQLEEVGKLRSVSMSPDDAPAVISMQRIGEV TH_3260|M.thermoresistible__bu SLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGEL MSMEG_0225|M.smegmatis_MC2_155 AVPIILVWVALIAVLNTIVPQLEEVGEMRSVSMSPDDAPSMIAMKRVGEV MAB_4382c|M.abscessus_ATCC_199 AVPIVLGWIAVTIALNTVVPQLEEVGHMRAVSMSPNDAPAMIATKRVGEV Mb0695c|M.bovis_AF2122/97 AVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKV Rv0676c|M.tuberculosis_H37Rv AVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKV MMAR_1005|M.marinum_M AVPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKV MUL_0757|M.ulcerans_Agy99 AVPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKV MAV_2510|M.avium_104 AVPIIIGWIALIAVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAV MLBr_02378|M.leprae_Br4923 AVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQV ::*::: *: :. :*.*: **. ::*.::*. * : :: :::* : Mvan_1614|M.vanbaalenii_PYR-1 FEEYESNSSVMIVLEGEQPLGDDTRRYYADLISGLEADTTHVEHVQDLWS Mflv_4825|M.gilvum_PYR-GCK FEEYESNSSVMIVLEGQEPLGDDTRAYYSELIADLEADTKHVEHIQDLWS TH_3260|M.thermoresistible__bu FDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWS MSMEG_0225|M.smegmatis_MC2_155 FEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADKTHIEHVQDFWG MAB_4382c|M.abscessus_ATCC_199 FEEFKTSSSVMIVLEGEQSLGADAHRFYDQMVRDLRADTTHVQHVQDFWA Mb0695c|M.bovis_AF2122/97 FEEGDSDSAAMIVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWG Rv0676c|M.tuberculosis_H37Rv FEEGDSDSAAMIVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWG MMAR_1005|M.marinum_M FREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWG MUL_0757|M.ulcerans_Agy99 FREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWG MAV_2510|M.avium_104 FNEYKSNSSVMIVLEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWS MLBr_02378|M.leprae_Br4923 FNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWG * * .:.* ******:..** :: :* :: *.** *:: :**:*. Mvan_1614|M.vanbaalenii_PYR-1 DPLTAAGAQSADGKSTYFQVYLAGNQGEALANESVRAVQELVA---ESQP Mflv_4825|M.gilvum_PYR-GCK DPLTAAGAQSADGMSTYFQVYLAGNQGEALANESVRAVQELVA---ESQP TH_3260|M.thermoresistible__bu DPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMA MSMEG_0225|M.smegmatis_MC2_155 DPLTASGAQSSDGLASYVQVYTAGNQGEALANESVKAVQDIVD---SVQA MAB_4382c|M.abscessus_ATCC_199 DALTAAAAQSSDGKAAYVQVYIAGDQGEALANESVEAVRHITA---AVPP Mb0695c|M.bovis_AF2122/97 DPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVE---RLAP Rv0676c|M.tuberculosis_H37Rv DPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVE---RLAP MMAR_1005|M.marinum_M DPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVD---SLQA MUL_0757|M.ulcerans_Agy99 DPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVD---SLQA MAV_2510|M.avium_104 DPLTGAGAQSNDGKASYVQVYLAGNQGEALANESVESVQNIVK---SVQA MLBr_02378|M.leprae_Br4923 DPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVV---QTPA *.**....** ** ::*.*: **:*** **:**: :*: : . Mvan_1614|M.vanbaalenii_PYR-1 PAGVKAFVTGASALAAEQEEAGHTSMRFVEALTFLVITIMLVLFFRSIVT Mflv_4825|M.gilvum_PYR-GCK PDGVAAYVTGASALAAEQEEAGHSSMRFVEALTFLVITIMLVLFFRSIVT TH_3260|M.thermoresistible__bu PEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVIT MSMEG_0225|M.smegmatis_MC2_155 PPGVTAYVTGPAAMSADQQIAGDRSMRMIEALTFTVIIIMLLMVYRSIIT MAB_4382c|M.abscessus_ATCC_199 SPGVRVYVTGPATTSADQEIVANDSMELIELVTFGVIMVMLLLVYRSVIT Mb0695c|M.bovis_AF2122/97 PPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIIT Rv0676c|M.tuberculosis_H37Rv PPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIIT MMAR_1005|M.marinum_M PPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIIT MUL_0757|M.ulcerans_Agy99 PPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIIT MAV_2510|M.avium_104 PNGVKAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVIT MLBr_02378|M.leprae_Br4923 PPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFIT . *: .:*** :: *: . .. *: : :. ** *::.:**.:* Mvan_1614|M.vanbaalenii_PYR-1 TLLILVMVGLSLMTVRGAVAFLGFHDIIGLSTFATSLLVTLAIAIAVDYA Mflv_4825|M.gilvum_PYR-GCK TLLILVMVGLSLMTVRGAVAFLGFHDIIGLSTFATSLLVTLAIAIAVDYA TH_3260|M.thermoresistible__bu VLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYA MSMEG_0225|M.smegmatis_MC2_155 VILSLVMVVFSLAAARGVIAFLGYYEIIGLSTFATNLLVTLAIAAATDYA MAB_4382c|M.abscessus_ATCC_199 MVIVVAMVMLELASARGLVALLSYHNAFGLTSFATSLVVTLAIAAATDYA Mb0695c|M.bovis_AF2122/97 SAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYA Rv0676c|M.tuberculosis_H37Rv SAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYA MMAR_1005|M.marinum_M AAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYA MUL_0757|M.ulcerans_Agy99 AAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYA MAV_2510|M.avium_104 VLLTLVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYA MLBr_02378|M.leprae_Br4923 VILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYG : : * : .** :*:*.. :**::**..*:. **** ..**. Mvan_1614|M.vanbaalenii_PYR-1 IFLVGRYQEAKGKGATAEEAYFTMFGGNAHVIVGSGLTIAGATFCLSFTR Mflv_4825|M.gilvum_PYR-GCK IFLIGRYQEAKGTGATSEEAYYTMFGGTAHVIVGSGLTIAGATFCLSFTR TH_3260|M.thermoresistible__bu IFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTR MSMEG_0225|M.smegmatis_MC2_155 IFLIGRYQEARSVGESREQAYYTMFHSTAHVVLGSGMTIAGATLCLHFTR MAB_4382c|M.abscessus_ATCC_199 IFLIGRYQEARRAGEDRESAYYTMFHGTAHVVLASGLTIAGATFCLHFTR Mb0695c|M.bovis_AF2122/97 IFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTR Rv0676c|M.tuberculosis_H37Rv IFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTR MMAR_1005|M.marinum_M IFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTR MUL_0757|M.ulcerans_Agy99 IFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTR MAV_2510|M.avium_104 IFLIGRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTN MLBr_02378|M.leprae_Br4923 IFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFAR **: ******: . *:.**: .. **: .**:**:***:** *:. Mvan_1614|M.vanbaalenii_PYR-1 LPYFQSLGVPLALGMLVLIAVAMTFGPAMVTIASKFG-LLEPKRAMRVRG Mflv_4825|M.gilvum_PYR-GCK LPYFQSLGVPLALGMLVLIAVAMTFGPAVVTVASKFG-LLAPKRDMRVRG TH_3260|M.thermoresistible__bu LPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRF MSMEG_0225|M.smegmatis_MC2_155 MPYFQSLGIPLAIGMTVVVLTALAVGPAIITVASRFGKTLEPKRAMRTRG MAB_4382c|M.abscessus_ATCC_199 LPYFKTTGIPLSIGMAIVVAMALTLGPALISVASRFGNVLEPKGAGKARG Mb0695c|M.bovis_AF2122/97 LPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRG Rv0676c|M.tuberculosis_H37Rv LPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRG MMAR_1005|M.marinum_M LPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRG MUL_0757|M.ulcerans_Agy99 LPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRG MAV_2510|M.avium_104 LPYFQTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRG MLBr_02378|M.leprae_Br4923 MPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRG :***:: * * ::** : : :::.***:::: ::* : *: : * Mvan_1614|M.vanbaalenii_PYR-1 WRKIGAVTVRWPGAILVASVAVSLIGLLALPGYQTSYNDRNYLPDDIQSN Mflv_4825|M.gilvum_PYR-GCK WRKVGAATVRWPGAILVASVAVSLIGLLALPGYQTSYNDRKYLPADIQSN TH_3260|M.thermoresistible__bu WRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSN MSMEG_0225|M.smegmatis_MC2_155 WRKVGAAVVRWPGPILVAAVGLSMIGLLALPGYRTNYNDRDYQPADLPAN MAB_4382c|M.abscessus_ATCC_199 WRRVGAATVRWPGAILVAAVTMALVGLLTLPGYHTTYNDRIYLPGQVPAN Mb0695c|M.bovis_AF2122/97 WRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPAN Rv0676c|M.tuberculosis_H37Rv WRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPAN MMAR_1005|M.marinum_M WRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPAN MUL_0757|M.ulcerans_Agy99 WRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPAN MAV_2510|M.avium_104 WRKVGTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPAN MLBr_02378|M.leprae_Br4923 WRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPAN **::*: **** .*:: : ::::***:****:*.*:** * * .. :* Mvan_1614|M.vanbaalenii_PYR-1 VGYAAAERHFSPARLNPEVLMVETDHDLRNPADFIVIEKIAKALFTVEGI Mflv_4825|M.gilvum_PYR-GCK IGYAAAERHFSPARLNPEVLMVETDHDLRNPADFIVIEKIAKALFAVEGI TH_3260|M.thermoresistible__bu AGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGI MSMEG_0225|M.smegmatis_MC2_155 SGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVIERIAKRVVGVPGV MAB_4382c|M.abscessus_ATCC_199 VGYAAADRHFSKAKMNPDLLLVESDHDLRNPADFLVIDKIAKALARVRGI Mb0695c|M.bovis_AF2122/97 EGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGI Rv0676c|M.tuberculosis_H37Rv EGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGI MMAR_1005|M.marinum_M EGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGI MUL_0757|M.ulcerans_Agy99 EGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGI MAV_2510|M.avium_104 EGYAAADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGI MLBr_02378|M.leprae_Br4923 QGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGI *: **:*** *:::*::*::*:***:**.:**::::::*: : * *: Mvan_1614|M.vanbaalenii_PYR-1 GRVQTITRPDGTPIESTSIPYIMSRQSTTQQLNEKYMLDRMDDMQVQAES Mflv_4825|M.gilvum_PYR-GCK GRVQTITRPDGKPIESTSIPYIMSRQNTTQQLNEKYMLDRMDDMRAQADS TH_3260|M.thermoresistible__bu SRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADE MSMEG_0225|M.smegmatis_MC2_155 SRVQAITRPQGTPIEHTSIPFTISMQGTTQTMNQKYMQDRMADMLVQADQ MAB_4382c|M.abscessus_ATCC_199 AQVQTITRPDGKPIKHTSIPFNMSTANTAQTLTNDYSQANFANLLKQADA Mb0695c|M.bovis_AF2122/97 SRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVND Rv0676c|M.tuberculosis_H37Rv SRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVND MMAR_1005|M.marinum_M SRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVND MUL_0757|M.ulcerans_Agy99 SRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVND MAV_2510|M.avium_104 GRVQAITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADM MLBr_02378|M.leprae_Br4923 SRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAEN .:** ****:*..:. :***: :* .. * . .* : *.: Mvan_1614|M.vanbaalenii_PYR-1 LQTTIDTMEKMQALMSQMSEITNSMVAKTKTMAVDITELRDHIADLDDFV Mflv_4825|M.gilvum_PYR-GCK LQTTINVMERMQALMTQMSAITTSMVGKTRTMTADITQLRDHIADLDDFV TH_3260|M.thermoresistible__bu MQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFF MSMEG_0225|M.smegmatis_MC2_155 MQVTVDTMTKMIALMEQMRDTMNSMVGKMHGMVDDIKELRDNISDFDDFF MAB_4382c|M.abscessus_ATCC_199 MQVTIDSMEKMQAITQQMAEVTASMSANMKNTAQDINQLRDNMSNFDDQF Mb0695c|M.bovis_AF2122/97 IQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFF Rv0676c|M.tuberculosis_H37Rv IQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFF MMAR_1005|M.marinum_M IQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFF MUL_0757|M.ulcerans_Agy99 IQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFF MAV_2510|M.avium_104 MQTTIDSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFF MLBr_02378|M.leprae_Br4923 MAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFW : : * :* : : : . .:*: :::::* Mvan_1614|M.vanbaalenii_PYR-1 RPIRNYFYWEPHCYNIPVCHSMRSLFDLIDGTNLLTDNVQDLVPDLERMA Mflv_4825|M.gilvum_PYR-GCK RPIRNYFYWEPHCYNIPVCHSMRSLFDLIDGTNLLTENTQELLPDLERMA TH_3260|M.thermoresistible__bu RPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLN MSMEG_0225|M.smegmatis_MC2_155 RPIRNYLYWEPHCYNIPMCYSLRSIFDTMDGIDTMTADFEQIVPDMDRMN MAB_4382c|M.abscessus_ATCC_199 RPIRNYFYWEKHCFDIPMCWALRSVFDALDGISLMSDDFDTLVPDIQRMA Mb0695c|M.bovis_AF2122/97 RPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLD Rv0676c|M.tuberculosis_H37Rv RPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLD MMAR_1005|M.marinum_M RPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLD MUL_0757|M.ulcerans_Agy99 RPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLD MAV_2510|M.avium_104 RPMRSYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLD MLBr_02378|M.leprae_Br4923 RPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMD **:*.*:*** **::**:* ::**:** :** . : : :: :..: Mvan_1614|M.vanbaalenii_PYR-1 AIMPELIALMPQQIETMKSQREMMLTQFQTQKGQLEAAAEMQVDAGAMGD Mflv_4825|M.gilvum_PYR-GCK AIMPELIALMPSQIESMKSQRDNMLTQYQTQNSQLEAGAEMSVDSGAMGD TH_3260|M.thermoresistible__bu DLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGE MSMEG_0225|M.smegmatis_MC2_155 ALIPVMIANMEPMITTMKTMKTMMLTMQATNAGLQDQMAAMQENSTAMGE MAB_4382c|M.abscessus_ATCC_199 GLMPQMVVLMPPMIASMKEQKQIMLSQYQVQKAQQDQTMAMQANASAMGQ Mb0695c|M.bovis_AF2122/97 TLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGE Rv0676c|M.tuberculosis_H37Rv TLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGE MMAR_1005|M.marinum_M TLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGE MUL_0757|M.ulcerans_Agy99 TLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGE MAV_2510|M.avium_104 TLMPQMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGK MLBr_02378|M.leprae_Br4923 LLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGK ::* : : : .*: : :*: . . : . :: :**. Mvan_1614|M.vanbaalenii_PYR-1 AFNDAWNADSFYLPPEAFENADFQSGIEQFISPNGHAVRFIIAHEGDPLS Mflv_4825|M.gilvum_PYR-GCK AFNDAWNADTFYLPPEAFENKDFQSGIEQFISPNGHAVRFIIAHEDDPLS TH_3260|M.thermoresistible__bu AFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMT MSMEG_0225|M.smegmatis_MC2_155 AFDKAKNDDSFYLPPETFDNPDFKRGMKMFLSPDGHAVRFIISHEGDPMS MAB_4382c|M.abscessus_ATCC_199 AFDDAKNDDSFYLPPEAFETADFKSGIKLFVSPNGHAVRFTIFHQSDPLT Mb0695c|M.bovis_AF2122/97 AFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMS Rv0676c|M.tuberculosis_H37Rv AFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMS MMAR_1005|M.marinum_M AFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMS MUL_0757|M.ulcerans_Agy99 AFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMS MAV_2510|M.avium_104 AFDASKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMT MLBr_02378|M.leprae_Br4923 AFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPAS **: : * *:******.*.. :*: .:: *:*.:***.** * * .** : Mvan_1614|M.vanbaalenii_PYR-1 PAGVEKIDKLKTAAKEAVKGTPLEGSKIYLGGTAATFKDMADGTRYDLLI Mflv_4825|M.gilvum_PYR-GCK PAGIEKIDGLKTAAKEAIKGTPLEGARVYLGGTAATFKDMADGTRYDLLI TH_3260|M.thermoresistible__bu PEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLII MSMEG_0225|M.smegmatis_MC2_155 PEGIQKIDDIKLAAKEAIKGTPLEGSKIYLGGTAATFKDMQEGANYDLII MAB_4382c|M.abscessus_ATCC_199 EEGTSRVEPLKTAAEDAIKGTPLEGSSIYVGGSAALYKDMQEGADYDLLI Mb0695c|M.bovis_AF2122/97 QAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMI Rv0676c|M.tuberculosis_H37Rv QAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMI MMAR_1005|M.marinum_M QAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTAAMFKDLSDGNTFDLMI MUL_0757|M.ulcerans_Agy99 QAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMI MAV_2510|M.avium_104 QEGISHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLI MLBr_02378|M.leprae_Br4923 VAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVI * : :: ** :*:******.: :*:.*:.: :**: :* :**:* Mvan_1614|M.vanbaalenii_PYR-1 AGIAAVGLIFIIMLILTRAIVAAAVIVGTVVLSLGASFGLSVLVWQHLVG Mflv_4825|M.gilvum_PYR-GCK AGIAAIGLIFIIMLILTRAVIAAAVIVGTVVLSLGASFGLSVLVWQHFVG TH_3260|M.thermoresistible__bu AAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVG MSMEG_0225|M.smegmatis_MC2_155 AGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGSAFGLSVLIWQHLVG MAB_4382c|M.abscessus_ATCC_199 AAVAALILIFLIMVLLTRAVVAAAVIVGTVVLSLGASFGLSVLLWQHIIG Mb0695c|M.bovis_AF2122/97 AGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILG Rv0676c|M.tuberculosis_H37Rv AGISALCLIFIIMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILG MMAR_1005|M.marinum_M AGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILG MUL_0757|M.ulcerans_Agy99 AGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLG MAV_2510|M.avium_104 AGISSLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIG MLBr_02378|M.leprae_Br4923 AGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILG *.:::: ***:**:: **..:*:******* :**.::**:***:**:.:* Mvan_1614|M.vanbaalenii_PYR-1 IELHWMVLPMAVIILLAVGADYNLLVVSRLKEEVGAGLHTGLIRTMGGSG Mflv_4825|M.gilvum_PYR-GCK IELHWMVLPMAVIILLAVGADYNLLVVSRLKEEIQAGVGTGLIRTMGGSG TH_3260|M.thermoresistible__bu LEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSG MSMEG_0225|M.smegmatis_MC2_155 LELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLDTGMIRAMGGSG MAB_4382c|M.abscessus_ATCC_199 TPLHWMVLPMAVIILLAVGADYNLLLVSRMKEELHAGLHTGTIRSMAGTG Mb0695c|M.bovis_AF2122/97 IELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSG Rv0676c|M.tuberculosis_H37Rv IELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSG MMAR_1005|M.marinum_M IELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSG MUL_0757|M.ulcerans_Agy99 IELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSG MAV_2510|M.avium_104 IELHWMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTG MLBr_02378|M.leprae_Br4923 IELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTG :*::*:.*::*:*****:*****:*:*:::*: **: ** **:*.*:* Mvan_1614|M.vanbaalenii_PYR-1 SVVTAAGMVFALTMMTMAVSDLTIIGQVGTTIGMGLIFDTLVIRSFMTPS Mflv_4825|M.gilvum_PYR-GCK SVVTAAGMVFALTMMTMAVSDLTIIGQVGTTIGMGLIFDTLVIRSFMTPS TH_3260|M.thermoresistible__bu SVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPS MSMEG_0225|M.smegmatis_MC2_155 SVVTAAGLVFAFTMMSMAVSELAIIGQVGTTIGLGLLFDTLVIRSFMTPS MAB_4382c|M.abscessus_ATCC_199 SVVTSAGLVFAFTMMGMMVSSFTVIGQIGTTIGLGLLFDTLVVRSFMTPS Mb0695c|M.bovis_AF2122/97 SVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPS Rv0676c|M.tuberculosis_H37Rv SVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPS MMAR_1005|M.marinum_M SVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPS MUL_0757|M.ulcerans_Agy99 SVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPS MAV_2510|M.avium_104 SVVTSAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPS MLBr_02378|M.leprae_Br4923 KVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPS .*** **:**.:** : **.: ::.*:*****:**:***:::**:* ** Mvan_1614|M.vanbaalenii_PYR-1 IAALLGRWFWWPQQIRTRPAPSPWPAPPARVADDTGR------------- Mflv_4825|M.gilvum_PYR-GCK IAALLGRWFWWPQKIRTRPVPVPWGAGASGGGDGDGDGDGDDGGGGAPRA TH_3260|M.thermoresistible__bu IATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV---------- MSMEG_0225|M.smegmatis_MC2_155 IAALLGKWFWWPQMVRRRPKPSPWPKPIQREPADAVN------------- MAB_4382c|M.abscessus_ATCC_199 IASLLGRWFWWPMVVRPRPRPQPWPQPLHAGAAEAVRA------------ Mb0695c|M.bovis_AF2122/97 IAALLGKWFWWPQVVRQRPVPQPWPSPASARTFALV-------------- Rv0676c|M.tuberculosis_H37Rv IAALLGKWFWWPQVVRQRPIPQPWPSPASARTFALV-------------- MMAR_1005|M.marinum_M IAALLGKWFWWPQVVRQRPAPQPWPTPAPTP--ATTSV------------ MUL_0757|M.ulcerans_Agy99 IAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV------------ MAV_2510|M.avium_104 IAALLGKWFWWPQRVRQRPVPSPWPKPAAQEREVLADA------------ MLBr_02378|M.leprae_Br4923 IAALLGRWFWWPQQGRTRPLLTVAAPVGLPPDRSLVYSD----------- **:***:***** * ** Mvan_1614|M.vanbaalenii_PYR-1 ----- Mflv_4825|M.gilvum_PYR-GCK RASAQ TH_3260|M.thermoresistible__bu ----- MSMEG_0225|M.smegmatis_MC2_155 ----- MAB_4382c|M.abscessus_ATCC_199 ----- Mb0695c|M.bovis_AF2122/97 ----- Rv0676c|M.tuberculosis_H37Rv ----- MMAR_1005|M.marinum_M ----- MUL_0757|M.ulcerans_Agy99 ----- MAV_2510|M.avium_104 ----- MLBr_02378|M.leprae_Br4923 -----