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MNDTRSVKRPAPLALSNWPVRVKVLAIVVVPLLLACVFGGLRIYSSATEAAELRHAAQRADMVPAVVDYM AALEAAMVTATEGGDARQALTVFESRRTGLQHLLDVTPVDDGVRLATNTLIDFGQNLIDKISADAIDLRT RVMTYAPLLITSETAITGLVGADDERVRSDADTLSRAVGARGQMAMQRMLVNSGAELPEPLLRSAMVTIA GTEPATVTAMGGYLGGATEQASTLRSEMVKRMALLSEPTTALVGNPELLASQKITGDIAAGLIAQTTEDI PAAVARQADDARTAAIRDAALVGAAILVALILVTLVARSMVRPLRTLRDSALKVAHEDLPREVEHVRSDG KEFPVQPIPVHTTEEVGQVAHAVDELHQQAVMLAGEQARLQLQVTDMFETLSRRNRSLVDQQLSLIDRLE RDEEDPDRLESLFRLDHLAARMRRNGSNLMVLAGAQISRERAESVPVTALVNAAASEVEDYTRIVTTGLP DGEVDGVVAGDLVHLLAELLDNALRYSPPTTEVRVSAVPTGNNGLVIEVSDTGLGMTESDLRVANTRLES GGEVNPYTARHMGLFVVGRLAASHGLVVRLRSTVAGEPDSGTTAGVYIPARLLIHTAPAQYGGRDDEPVP ADAHAGIATALALEVPAGVPREAPAAAAGPATDLLPQRRPGASGIVETPAETPVAPIETPVATSVAVVTP AATPVAAVTPVAPPVETPPARSEVAAFFSPRPQPTETNGHARHAAADSDPDDAIYQKMLSEWLVDPHELS HSTDLNWKSVWDHGWSAAEAAEAAPVLDHTAEGLPVRRPGARLVPGHANGEPVASAGRDPEAVRNSIGSH FGGVHAGRLRAQETGGADFP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1536 | - | - | 100% (860) | integral membrane sensor signal transduction histidine kinase |
| M. vanbaalenii PYR-1 | Mvan_0830 | - | 2e-10 | 27.09% (251) | histidine kinase |
| M. vanbaalenii PYR-1 | Mvan_4843 | - | 3e-10 | 23.89% (314) | integral membrane sensor signal transduction histidine kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3400c | - | 0.0 | 49.60% (875) | hypothetical protein Mb3400c |
| M. gilvum PYR-GCK | Mflv_4889 | - | 0.0 | 68.41% (858) | integral membrane sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv3365c | - | 0.0 | 49.60% (875) | hypothetical protein Rv3365c |
| M. leprae Br4923 | MLBr_00175 | - | 2e-09 | 23.29% (322) | putative two-component system sensor kinase |
| M. abscessus ATCC 19977 | MAB_1721 | - | 3e-12 | 26.07% (326) | putative histidine kinase sensor of two-component system |
| M. marinum M | MMAR_1165 | - | 0.0 | 49.72% (889) | putative regultory protein |
| M. avium 104 | MAV_4331 | - | 0.0 | 50.38% (913) | hypothetical protein MAV_4331 |
| M. smegmatis MC2 155 | MSMEG_1637 | - | 0.0 | 53.98% (930) | periplasmic sensor signal transduction histidine kinase |
| M. thermoresistible (build 8) | TH_3044 | - | 0.0 | 63.00% (554) | PUTATIVE integral membrane sensor signal transduction histidine |
| M. ulcerans Agy99 | MUL_2850 | - | 0.0 | 49.89% (890) | putative regultory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3400c|M.bovis_AF2122/97 MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTI
Rv3365c|M.tuberculosis_H37Rv MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTI
MMAR_1165|M.marinum_M MTMFARPTTPVEAAPG--APVASGAESAPPKRPPAWSLGNWPVGWKVVAI
MUL_2850|M.ulcerans_Agy99 MTMFARLTTPVEAAPG--APVASGAESAPPKRPPAWSLGNWPVGWKVVAI
MAV_4331|M.avium_104 MTMFSRPAEPAAAEAP--GPAPLGGGAVPAKRPPAWSLSNWPVRWKVLAI
Mvan_1536|M.vanbaalenii_PYR-1 -----------------------MNDTRSVKRPAPLALSNWPVRVKVLAI
Mflv_4889|M.gilvum_PYR-GCK ----------------------MARSLRPDQRPSRWAPPNWPVRVKVLAL
MSMEG_1637|M.smegmatis_MC2_155 ------------------------------------------MSRKVLAI
TH_3044|M.thermoresistible__bu MTVFSQLRKSDGTNRD-----VEPPAPDPIKKPSRWALTNWPVRWKVFAI
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 -----------------------MVRFAWRRRASLRATSSLSLRWRVMLL
Mb3400c|M.bovis_AF2122/97 ALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAV
Rv3365c|M.tuberculosis_H37Rv ALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAV
MMAR_1165|M.marinum_M AVVPLLLAMVLGGLRIHGGMANSSGLRLADARADVIPAITKYMSALDVAL
MUL_2850|M.ulcerans_Agy99 AVVPLLLAMVLGGLRIHGGMANSSGLRLADARADVIPAITKYMSALDVAL
MAV_4331|M.avium_104 VLVPLMLATVFGVLRIHGAMANAAGLRLAAARADVVPAITKYMSALDVAL
Mvan_1536|M.vanbaalenii_PYR-1 VVVPLLLACVFGGLRIYSSATEAAELRHAAQRADMVPAVVDYMAALEAAM
Mflv_4889|M.gilvum_PYR-GCK VTVPLVLACVFGGLRISASTVEARELAHAADRAQMVPAVVDYMAALQNAM
MSMEG_1637|M.smegmatis_MC2_155 VLVPLILAATFGGLRIYASVTEAADLRLAADRAELIPDINNYMAALEGVL
TH_3044|M.thermoresistible__bu VLVPLLLIATFAGLRVYSGVAENAELRRAVDRAEVIPPVVDYMAALEEAM
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 AMSMVAMVVVLMAFAVYVVIS-----------AALYSDIDNQLQSRAQLL
Mb3400c|M.bovis_AF2122/97 LASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQAL
Rv3365c|M.tuberculosis_H37Rv LASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQAL
MMAR_1165|M.marinum_M LASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSVLNGGQAL
MUL_2850|M.ulcerans_Agy99 LASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSVLNGGQAL
MAV_4331|M.avium_104 LAGSAGRDAEGAKKNYEARKNELQTRLGDTDVTDDVRAGVNNLLDTGQML
Mvan_1536|M.vanbaalenii_PYR-1 VTATEGGDARQALTVFESRRTGLQHLLDVTPVDDGVRLATNTLIDFGQNL
Mflv_4889|M.gilvum_PYR-GCK VTAGGGGNPAAALGEFDFRKAELSRVLEGADVDDSVRLATNTLLEYGQNL
MSMEG_1637|M.smegmatis_MC2_155 VASSGAGDGQAALATFDSRKSELQQRVDSTDVLGDVREAVGTMLDKGQTL
TH_3044|M.thermoresistible__bu VAATTGRETQPALARFDERKTELRERAEQGEIVPDVRAAVDTLLDGGQDL
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 IASG----------------------------------------------
Mb3400c|M.bovis_AF2122/97 LDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRA
Rv3365c|M.tuberculosis_H37Rv LDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRA
MMAR_1165|M.marinum_M LDQTLANTISLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRA
MUL_2850|M.ulcerans_Agy99 LDQTLANTSSLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRA
MAV_4331|M.avium_104 VNKVAEGSLGLRERVTFYAPILLTAENVINASVRVDDERIRAQAQGLSRA
Mvan_1536|M.vanbaalenii_PYR-1 IDKISADAIDLRTRVMTYAPLLITSETAITGLVGADDERVRSDADTLSRA
Mflv_4889|M.gilvum_PYR-GCK LDRIGAAEMNLRTQVMTFGPLLITAQTALTGSVGSDEDSVRTEADVLSRA
MSMEG_1637|M.smegmatis_MC2_155 VDASMANTVGLRQRILDYAPLLLTAEAAVTGSTHSADQRVQTEAEALGRA
TH_3044|M.thermoresistible__bu INKVMSNVVDLRQRVTAYAPLLLTAETAITGSARDDAPGVQRKAEALSRA
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 -------------------SLAADPGKAIEGTAYSDVN------------
Mb3400c|M.bovis_AF2122/97 VGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAG
Rv3365c|M.tuberculosis_H37Rv VGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAG
MMAR_1165|M.marinum_M VGARGQMTLQEILVTRGAEAPEAQLRNSMITLAGTEPSTLFGMTEVLGVG
MUL_2850|M.ulcerans_Agy99 VGARGQMTLQEILVTRGVEAPEAQLRNSMITLAGTGPSTLFGMTEVLGVG
MAV_4331|M.avium_104 VGARGQMTMQKILVTRGAELPEPQLRTSMATLAGTEPSTLFGMSEVLGAG
Mvan_1536|M.vanbaalenii_PYR-1 VGARGQMAMQRMLVNSGAELPEPLLRSAMVTIAGTEPATVTAMGGYLGGA
Mflv_4889|M.gilvum_PYR-GCK VGARGQMAMQDMLVTRGGELPEPLLRSAMVTLAGTEPATVTAMGTFLGGA
MSMEG_1637|M.smegmatis_MC2_155 IGARGQMTIQEMMVNRGAEEPEPVLRKSMITMAGTEPSTVAALTKVLGSA
TH_3044|M.thermoresistible__bu VGARGQMTMQEMSVTSGGYLPEPELRTSLITLAGTEPSTINGMIAYLGND
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 ---------------------------AMLVNPGHSIYTANQPGQTLPVG
Mb3400c|M.bovis_AF2122/97 SPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTT
Rv3365c|M.tuberculosis_H37Rv SPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTT
MMAR_1165|M.marinum_M SPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQSIQITRGIAEQVINDAT
MUL_2850|M.ulcerans_Agy99 SPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQSIQITRGIAEQVINDAT
MAV_4331|M.avium_104 SPEAKTLQQQMVSRMAIMSDPASVLVDNPDLLRSIQTTDDIADQVIKNTT
Mvan_1536|M.vanbaalenii_PYR-1 TEQASTLRSEMVKRMALLSEPTTALVGNPELLASQKITGDIAAGLIAQTT
Mflv_4889|M.gilvum_PYR-GCK SDRADALRSQMVRRMSLLSDPAVVLVGNPELLMSQKITADIAQSLINRIA
MSMEG_1637|M.smegmatis_MC2_155 SDDATTLRDEMVKRMAIMANPGIPLVGNPVLLESLENTRKIAEQIITDNT
TH_3044|M.thermoresistible__bu SQQAATLRTEMVRRMSMMSDPAVPLAANPELLGSQQVTRSVADAMIAELA
MAB_1721|M.abscessus_ATCC_1997 ----------MSQLLELLPRPLDPLR-----------SFKFKTAVLVGVA
MLBr_00175|M.leprae_Br4923 TAEKAVIRGELFMSQRTASD-----------------QRILAIHLPNDSS
: . . : :
Mb3400c|M.bovis_AF2122/97 EAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVL
Rv3365c|M.tuberculosis_H37Rv EAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVL
MMAR_1165|M.marinum_M ESVTKAVQARASARRDAAIRDTVFVLGAILVAVVVVLLVARALVRPLRQL
MUL_2850|M.ulcerans_Agy99 ESVTKAVQARASARRDAAIRDTVLVLGAILVAVVVVLLVARALVRPLRQL
MAV_4331|M.avium_104 ASVTKSVHAQAAERRNSAILDTALVLAAIVIALAVVLLVARALVRPLRTL
Mvan_1536|M.vanbaalenii_PYR-1 EDIPAAVARQADDARTAAIRDAALVGAAILVALILVTLVARSMVRPLRTL
Mflv_4889|M.gilvum_PYR-GCK DEIPARVSRQADDARTAAIRDSVLVGAAILVALILVLWVARSLVRPLRTL
MSMEG_1637|M.smegmatis_MC2_155 SAIPAAVEAEAADARNDAIRDSVLVALAVISALVVVLLVARSLVRPLRTL
TH_3044|M.thermoresistible__bu TTIPDEVRQAADDQRTAAIRDTVLVLLAIAVAAVVVLLVARSLVRPLRTL
MAB_1721|M.abscessus_ATCC_1997 LLIATCLLWITAEWK-----LRYALTLALFVSFGVTWFLAHGMTSPLRDM
MLBr_00175|M.leprae_Br4923 LLISKSLRPTEAVMTKLRWVLLIVGSLGVAVAAVAGGMVTRAGLRPVGRL
:. : .: : ::: *: :
Mb3400c|M.bovis_AF2122/97 RDGALKVAHTDLDGEIAAVRAG-DEPIPEPLAVYTTEEIGQVAHAVDELH
Rv3365c|M.tuberculosis_H37Rv RDGALKVAHTDLDGEIAAVRAG-DEPIPEPLAVYTTEEIGQVAHAVDELH
MMAR_1165|M.marinum_M RDGALKVAHTDLEGEIAKVRAG-AEPIPEPLPVYTTEEIGQVAHAVDELH
MUL_2850|M.ulcerans_Agy99 RDGALKVAHTDLEGEIAKVREG-AEPIPEPLPVYTTEEIGQVAHAVDELH
MAV_4331|M.avium_104 RDGALKVAHTDLEEEIAHVKAGGAEPIPAPLPVYTTEEIGQVAHAVDELH
Mvan_1536|M.vanbaalenii_PYR-1 RDSALKVAHEDLPREVEHVRSDGKEFPVQPIPVHTTEEVGQVAHAVDELH
Mflv_4889|M.gilvum_PYR-GCK RDSALRVAHDDLGREVERVRDDGKEFAVDPIPVHTTEEVGQVAHAVDELH
MSMEG_1637|M.smegmatis_MC2_155 RDGALKVAHEDLAKEIERVRAGGEPGPITPLPVYTSEEVGQVAHAVDELH
TH_3044|M.thermoresistible__bu RDSALKVAHGDLARELDQVRETGELPEVEPIAVHTTEEIGQVAHAVDELH
MAB_1721|M.abscessus_ATCC_1997 TAAARSMAQGDYSRRIRSTSRD---------------EVGQLATAFNHMA
MLBr_00175|M.leprae_Br4923 TEAAERVARTDDLRPIPVFGSD---------------ELARLTEAFNLML
.* :*: * : *:.::: *.: :
Mb3400c|M.bovis_AF2122/97 TRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPA
Rv3365c|M.tuberculosis_H37Rv TRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPA
MMAR_1165|M.marinum_M AQVLVLAGDEARLRSLVNDMFETMSRRSRSLVDQQLSLIDGLERNEEDPE
MUL_2850|M.ulcerans_Agy99 AQVLVLAGDEARLRSLVNDMFETMSRRSRSLVDQQLSLIDGLERNEEDPD
MAV_4331|M.avium_104 TQALLLAGDEARLRLLVNDMFETMSRRSRSLVDQQLALIDRLERNEDNPE
Mvan_1536|M.vanbaalenii_PYR-1 QQAVMLAGEQARLQLQVTDMFETLSRRNRSLVDQQLSLIDRLERDEEDPD
Mflv_4889|M.gilvum_PYR-GCK QQALVLAGAQARLQLQVTDMFETLSRRNRSLVEQQLSLIDGLERDEEDPD
MSMEG_1637|M.smegmatis_MC2_155 EQAVFLAGEQAQLQLQVADMFETLSRRSRSLVDQQLSLIDELERNEDDPQ
TH_3044|M.thermoresistible__bu EQAVFLAGEQTRLQMQISDMFETLSRRSRSLVDQQLALIDQLERNEEDPQ
MAB_1721|M.abscessus_ATCC_1997 AELQSAERYRRELVGNVSHELRTPITALQAVLEN---IVDGVAE--PDPQ
MLBr_00175|M.leprae_Br4923 RALAESRERQARLVTDAGHELRTPLTSLRTNVELLIASMAPEAPRLPDQE
. .* . :.* :: :: : :
Mb3400c|M.bovis_AF2122/97 RLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSE
Rv3365c|M.tuberculosis_H37Rv RLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSE
MMAR_1165|M.marinum_M RLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVISAAVSE
MUL_2850|M.ulcerans_Agy99 RLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVISAAVSE
MAV_4331|M.avium_104 RLDNLFRLDHLAARLRRNSANLLVLAGAKLARDQRDPVPLATVINAAVSE
Mvan_1536|M.vanbaalenii_PYR-1 RLESLFRLDHLAARMRRNGSNLMVLAGAQISRERAESVPVTALVNAAASE
Mflv_4889|M.gilvum_PYR-GCK RLQSLFQLDHLAARMRRNGANLLVLAGARISHDRAEPVAVAAIVNAAASE
MSMEG_1637|M.smegmatis_MC2_155 RLNSLFRLDHLAARMRRNGANLLVLSGAKVTREKSEPVAVATVINAAASE
TH_3044|M.thermoresistible__bu RLQNLFRLDHLAARMRRNGANLLVLAGAKVPREQAAPMPVASLIHAAASE
MAB_1721|M.abscessus_ATCC_1997 TLKTALAQTERLGRLVDDLLDLSKLENGSVPVQR-ESFAVREFVDDAVAE
MLBr_00175|M.leprae_Br4923 MADLRADVLAQIEELSTLVGDLVDLTRDDAGQVVHEPIDMSEVLYRSLER
. .: :* * .. : .: : .
Mb3400c|M.bovis_AF2122/97 VEDYRRVDIARVPDCAVVGAAAGG---VIHLLAELIDNALRYSSPTTPVR
Rv3365c|M.tuberculosis_H37Rv VEDYRRVDIARVPDCAVVGAAAGG---VIHLLAELIDNALRYSSPTTPVR
MMAR_1165|M.marinum_M VEDYRRVETGGVADCTVIGAAAGA---VIHLLAELIDNALNYSPPTAPVR
MUL_2850|M.ulcerans_Agy99 VEDYRRVETGGVADCTVIGAAAGA---VIHLLAELIDNALNYSPPTAPVR
MAV_4331|M.avium_104 VEDYRRVEIAGLPECSLLGAAAGG---AIHLFAELIDNALRYSPPTTSAR
Mvan_1536|M.vanbaalenii_PYR-1 VEDYTRIVTTGLPDGEVDGVVAGD---LVHLLAELLDNALRYSPPTTEVR
Mflv_4889|M.gilvum_PYR-GCK VEEYPRIVTGDLPDSEVAASAAGD---LVHLLAELLDNGLRYSPPHTQVR
MSMEG_1637|M.smegmatis_MC2_155 VEDYTRVVTSDVADADVVGSAAGD---LIHLLAELLDNALRYSPPTSQVR
TH_3044|M.thermoresistible__bu VEDYTRIVMTTVPDSEVHGSVAGD---LVHILAELLDNALRYSPPTAQVR
MAB_1721|M.abscessus_ATCC_1997 AKTTGRQVRYHVTVEPFDLAAVADTARLHQVVANLLDNASRHSPPGGQVS
MLBr_00175|M.leprae_Br4923 VRRRRNDIHFDVQAIGWQIYGDAAG--LSRAVLNLMDNAAKWSPSGGRVV
.. . : . : . :*:**. . *.. .
Mb3400c|M.bovis_AF2122/97 VAAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTP----DSAR
Rv3365c|M.tuberculosis_H37Rv VAAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTP----DSAR
MMAR_1165|M.marinum_M VSAVRGSEGGVLLRIADSGLGMTESDRRMANMRLHAGVEVTP----ANAR
MUL_2850|M.ulcerans_Agy99 VSAVRGSEGGVLLRIADSGLGMTESDRRMANMRLHSGGEVTP----ANAR
MAV_4331|M.avium_104 VSASRGGDGGVVVRIADSGLGMNDADRRIANMRLQAGGDANPDPHPENAR
Mvan_1536|M.vanbaalenii_PYR-1 VSAVPTGNNGLVIEVSDTGLGMTESDLRVANTRLESGGEVNP----YTAR
Mflv_4889|M.gilvum_PYR-GCK VSAVPTDNNGLVIEVSDTGLGMTEADLRVANMRLESGGEVNP----YTAR
MSMEG_1637|M.smegmatis_MC2_155 VSAVFAGNGALVIEVADVGLGMTESDLRVANIRLKSGGEVNP----YTAR
TH_3044|M.thermoresistible__bu VSAGHADTGALVIEVSDAGLGMSESDLRMANARLESXX------------
MAB_1721|M.abscessus_ATCC_1997 VFAR-TENDALLLEVADTGPGIAPHERSRVFERFTHGGSRDG------GT
MLBr_00175|M.leprae_Br4923 VTMRQFDPSHVELVVSDYGPGIPPQERRLVFERFYRSTTARS----LPGS
* . : : ::* * *: : . *:
Mb3400c|M.bovis_AF2122/97 HMGLFVVGRLAGRHGIRVGLRGPVTGEQGT---GTTAEVYLPLAVLEG--
Rv3365c|M.tuberculosis_H37Rv HMGLFVVGRLAGRHGIRVGLRGPVTGEQGT---GTTAEVYLPLAVLEG--
MMAR_1165|M.marinum_M HMGLFVVGRLAARHGIRVGLRGPSTGEAGG---GTTAEVYLPRTVLVDGQ
MUL_2850|M.ulcerans_Agy99 HMGLFVVGRLAARHGIRVGLRGPSTGEAGG---GTTAEVYLPRTVLVDGQ
MAV_4331|M.avium_104 HLGLFVVGRIAAWHGMRVGLRGPAANESGS---GTTAEVYLPPTVLAG--
Mvan_1536|M.vanbaalenii_PYR-1 HMGLFVVGRLAASHGLVVRLRSTVAGEPDS---GTTAGVYIPARLLIHTA
Mflv_4889|M.gilvum_PYR-GCK HMGLFVVSRLAAQHGLVARLRSTVAGQPDS---GTTAGVYIPARLLVRRA
MSMEG_1637|M.smegmatis_MC2_155 HMGLFVVGRLADQHGLVVRLRSTIPDEPGS---GTTAGVYVPAQLLVTEA
TH_3044|M.thermoresistible__bu -----XAGRRCPGRAPTPRVGCRAHTCPHC---GSRA---PPAQ------
MAB_1721|M.abscessus_ATCC_1997 GLGLAIAQWAVDLHGG----RIEIVDAPGCRVR-----------------
MLBr_00175|M.leprae_Br4923 GLGLAIVKQVVINHGGLLRVEDTAPGVQPP---GTSIYVLLPGRPMPVS-
. :.
Mb3400c|M.bovis_AF2122/97 ---TAPAQPPKPRVFA---IKPPCPEPAAA------DPTDVPAAIGP---
Rv3365c|M.tuberculosis_H37Rv ---TAPAQPPKPRVFA---IKPPCPEPAAA------DPTDVPAAIGP---
MMAR_1165|M.marinum_M RPGPAAGQPPQRRAVV---VRPPSSEPAPAPDAAGSAPTGDSTAVPP---
MUL_2850|M.ulcerans_Agy99 RPGSAAGQPPQRSAFV---VRPPSSEPAPAPDAAGSAPTGDSTAVPP---
MAV_4331|M.avium_104 RVVAEPSGPRHIRAVSSPSAKLASAIAAPAEEGGRHDGTQQPAARGTRNT
Mvan_1536|M.vanbaalenii_PYR-1 ----PAQYGGRDDEPVPADAHAGIATALALEVPAGVPREAPAAAAGP---
Mflv_4889|M.gilvum_PYR-GCK ----APPVQARDVRPAAPAPAP-------TPAPAPAP-PPPPAPVVP---
MSMEG_1637|M.smegmatis_MC2_155 GTAGTPAFDQFDAQPEDAATAPGHPTGYPNVVSLDTRFVTTGSEHDDD--
TH_3044|M.thermoresistible__bu ----PPGSEQQGGEP-------------------------PVEHLTVG--
MAB_1721|M.abscessus_ATCC_1997 --VTLPQFDNEEGNS-----------------------------------
MLBr_00175|M.leprae_Br4923 --AYSTLADQDMGEAN----------------------------------
.
Mb3400c|M.bovis_AF2122/97 ----LPPVTLLPRRTPGSSGIADVP---AQPMQQ----RRRELKTPWWED
Rv3365c|M.tuberculosis_H37Rv ----LPPVTLLPRRTPGSSGIADVP---AQPMQQ----RRRELKTPWWED
MMAR_1165|M.marinum_M ----LPPVSLLPRRNPGSSGIADVPG--QQPEQQQPPRRRRELKTPWWET
MUL_2850|M.ulcerans_Agy99 ----LPPVSLLPRRNPGSSGIADVPG--QQPEQQQPPRRRRELKTPWWET
MAV_4331|M.avium_104 GDASTPPVTLLPRRNPGSSGIADVAAVPAPPAEPQPRRQRRELATPWWEA
Mvan_1536|M.vanbaalenii_PYR-1 ------ATDLLPQRRPGASGIVETP----AETPVAPIETPVATSVAVVTP
Mflv_4889|M.gilvum_PYR-GCK ------PADVLPQRRP---------------EPPPPVEPP----------
MSMEG_1637|M.smegmatis_MC2_155 -----LAAGLLPQRNPGASGISEMPGVFAEPEPAAEVSGDAQGEWPQQWP
TH_3044|M.thermoresistible__bu -----IADGVHQRAQP---------------QHPAPVTGER---------
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 R----------FQQEPKQPPAP-------------------------EPR
Rv3365c|M.tuberculosis_H37Rv R----------FQQEPKQPPAP-------------------------EPR
MMAR_1165|M.marinum_M A----------QPAGQPEQAAPQ----QSDTAAFFARRSPAAGAGPDEPA
MUL_2850|M.ulcerans_Agy99 A----------QPAGRPEQAAPQ----QSDTAAFFARRSPAAGAGPDEPA
MAV_4331|M.avium_104 SPAPRPAPEPQQPAPEPQQPAPRPARAASDTSAFFAARPRTETPPETPPE
Mvan_1536|M.vanbaalenii_PYR-1 AATPVAAVTPVAPPVETPPARSEVAAFFSPRPQ----------PTETNGH
Mflv_4889|M.gilvum_PYR-GCK ------------PPVETPP------------------------PVETP--
MSMEG_1637|M.smegmatis_MC2_155 APQEAAAPEEVAPQANGRPTDTSSFFASRAQAAGGTQNGAQVNGVHLDGA
TH_3044|M.thermoresistible__bu --------------------------------------------------
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 PAPPPAK-----------------PAPPAGPVDDDVIYRRMLSEMVGDPH
Rv3365c|M.tuberculosis_H37Rv PAPPPAK-----------------PAPPAGPVDDDVIYRRMLSEMVGDPH
MMAR_1165|M.marinum_M PSVKPGP-----------------PSALADPARDDSIYQKMLSEMTSDPH
MUL_2850|M.ulcerans_Agy99 PSVKPGP-----------------PSVPADPVRDDSIYQKMLSEMTSDPH
MAV_4331|M.avium_104 APPKPAPKPK--------PEASIPPAASTGPADDDVIYRRMLSEMLGDPH
Mvan_1536|M.vanbaalenii_PYR-1 ARHAAAD-----------------------SDPDDAIYQKMLSEWLVDPH
Mflv_4889|M.gilvum_PYR-GCK -RPGHAD-----------------------IDHDDTIYQKMLSEWLVDPH
MSMEG_1637|M.smegmatis_MC2_155 HTNGAANGTADSFTGFFGSSDDQLDQREPAGDPGDSIYQSMVSEFAIDPT
TH_3044|M.thermoresistible__bu -------------------------------------FGGLDVQFAVEGV
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 ELAHSPDLDWKSVWDHGWSAAAEAADKPVQSR-TDYGLPVREPGARLVPG
Rv3365c|M.tuberculosis_H37Rv ELAHSPDLDWKSVWDHGWSAAAEAADKPVQSR-TDYGLPVREPGARLVPG
MMAR_1165|M.marinum_M ELANSADLDWRSVWDRGWSAAAEAQDTPVQSR-TDHGLPVRTPGARLVPG
MUL_2850|M.ulcerans_Agy99 ELANSADLDWRSVWDRGWSAAAEAQETPVQSR-TDHGLPVRTPGARLVPG
MAV_4331|M.avium_104 DLVNSPDLDWQSVWDRGWTLAAAAEDKPVESHTTDHGLPVRTPGARLVPG
Mvan_1536|M.vanbaalenii_PYR-1 ELSHSTDLNWKSVWDHGWSAAEAAEAAPVLDH-TAEGLPVRRPGARLVPG
Mflv_4889|M.gilvum_PYR-GCK ELSHSSDLNWKSVWDNGWSAAEAADAAPVRHR-TPEGLPVRRPGARLIPG
MSMEG_1637|M.smegmatis_MC2_155 THARSADLDWQTVWEKGWSVAAAAQDAPVDRH-TEEGLPMRTPGARLVPG
TH_3044|M.thermoresistible__bu ALVHR----------AGVVAGLPAEHGDQVGQ-QAGGLRQRQPDG-----
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 -------------FQDKIGPAVQVSGKSANFRDSAHVISVDYQSARAR--
Mb3400c|M.bovis_AF2122/97 AAVPEGPDREHPGAALASN--------------------GGLHPGRAPRH
Rv3365c|M.tuberculosis_H37Rv AAVPEGPDREHPGAALASN--------------------GGLHPGRAPRH
MMAR_1165|M.marinum_M AADSDEPNQDEADRPPASD--------------------RGLPPDQPAQH
MUL_2850|M.ulcerans_Agy99 AADSDEPTQDEADRPPASD--------------------RGLPPDQPAQH
MAV_4331|M.avium_104 GAHG---AAAEPDDEPGLN--------------------GRSPAPRRPQH
Mvan_1536|M.vanbaalenii_PYR-1 ------------------------------------------HANGEP-V
Mflv_4889|M.gilvum_PYR-GCK ------------------------------------------HADTENGH
MSMEG_1637|M.smegmatis_MC2_155 GVAAAAGRTNGANGHHHSDLNGGVNGEIHGNDNGAEAVASANEADNGMFA
TH_3044|M.thermoresistible__bu --------------------------------------------------
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 AAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
Rv3365c|M.tuberculosis_H37Rv AAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
MMAR_1165|M.marinum_M TAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
MUL_2850|M.ulcerans_Agy99 TAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
MAV_4331|M.avium_104 AAVARDPEAVRASFSSHFGGVRTGRSHARESSEGPDQQ
Mvan_1536|M.vanbaalenii_PYR-1 ASAGRDPEAVRNSIGSHFGGVHAGRLRAQETGGADFP-
Mflv_4889|M.gilvum_PYR-GCK PLPVRDPDAVRASLGGHFGGVHAGRRHAREAAGDDR--
MSMEG_1637|M.smegmatis_MC2_155 AFKPRDPEAVRASISSHFGGVHAGRSHARETRGTDNE-
TH_3044|M.thermoresistible__bu ------VPAVDQPLP-------AGT-------------
MAB_1721|M.abscessus_ATCC_1997 --------------------------------------
MLBr_00175|M.leprae_Br4923 --------------------------------------