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MTMFARPTTPVEAAPGAPVASGAESAPPKRPPAWSLGNWPVGWKVVAIAVVPLLLAMVLGGLRIHGGMAN SSGLRLADARADVIPAITKYMSALDVALLASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNS VLNGGQALLDQTLANTISLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRAVGARGQMTLQEI LVTRGAEAPEAQLRNSMITLAGTEPSTLFGMTEVLGVGSPDAKTLHQQMVTRMAIISDPDSVLAGNPQLL QSIQITRGIAEQVINDATESVTKAVQARASARRDAAIRDTVFVLGAILVAVVVVLLVARALVRPLRQLRD GALKVAHTDLEGEIAKVRAGAEPIPEPLPVYTTEEIGQVAHAVDELHAQVLVLAGDEARLRSLVNDMFET MSRRSRSLVDQQLSLIDGLERNEEDPERLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTV ISAAVSEVEDYRRVETGGVADCTVIGAAAGAVIHLLAELIDNALNYSPPTAPVRVSAVRGSEGGVLLRIA DSGLGMTESDRRMANMRLHAGVEVTPANARHMGLFVVGRLAARHGIRVGLRGPSTGEAGGGTTAEVYLPR TVLVDGQRPGPAAGQPPQRRAVVVRPPSSEPAPAPDAAGSAPTGDSTAVPPLPPVSLLPRRNPGSSGIAD VPGQQPEQQQPPRRRRELKTPWWETAQPAGQPEQAAPQQSDTAAFFARRSPAAGAGPDEPAPSVKPGPPS ALADPARDDSIYQKMLSEMTSDPHELANSADLDWRSVWDRGWSAAAEAQDTPVQSRTDHGLPVRTPGARL VPGAADSDEPNQDEADRPPASDRGLPPDQPAQHTAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQ Q
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1165 | - | - | 100% (911) | putative regultory protein |
| M. marinum M | MMAR_4528 | mprB | 2e-14 | 22.44% (468) | two-component sensor kinase MprB |
| M. marinum M | MMAR_5451 | - | 8e-09 | 23.92% (301) | hypothetical protein MMAR_5451 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3400c | - | 0.0 | 69.04% (914) | hypothetical protein Mb3400c |
| M. gilvum PYR-GCK | Mflv_4889 | - | 0.0 | 48.52% (880) | integral membrane sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv3365c | - | 0.0 | 69.04% (914) | hypothetical protein Rv3365c |
| M. leprae Br4923 | MLBr_00175 | - | 3e-13 | 23.01% (365) | putative two-component system sensor kinase |
| M. abscessus ATCC 19977 | MAB_1077 | - | 4e-11 | 22.97% (418) | two component sensor kinase MprB |
| M. avium 104 | MAV_4331 | - | 0.0 | 64.78% (954) | hypothetical protein MAV_4331 |
| M. smegmatis MC2 155 | MSMEG_1637 | - | 0.0 | 51.35% (925) | periplasmic sensor signal transduction histidine kinase |
| M. thermoresistible (build 8) | TH_3044 | - | 1e-169 | 52.13% (633) | PUTATIVE integral membrane sensor signal transduction histidine |
| M. ulcerans Agy99 | MUL_2850 | - | 0.0 | 98.02% (911) | putative regultory protein |
| M. vanbaalenii PYR-1 | Mvan_1536 | - | 0.0 | 49.72% (889) | integral membrane sensor signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1165|M.marinum_M MTMFARPTTPVEAAPG--APVASGAESAPPKRPPAWSLGNWPVGWKVVAI
MUL_2850|M.ulcerans_Agy99 MTMFARLTTPVEAAPG--APVASGAESAPPKRPPAWSLGNWPVGWKVVAI
Mb3400c|M.bovis_AF2122/97 MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTI
Rv3365c|M.tuberculosis_H37Rv MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTI
MAV_4331|M.avium_104 MTMFSRPAEPAAAEAP--GPAPLGGGAVPAKRPPAWSLSNWPVRWKVLAI
Mflv_4889|M.gilvum_PYR-GCK ----------------------MARSLRPDQRPSRWAPPNWPVRVKVLAL
Mvan_1536|M.vanbaalenii_PYR-1 -----------------------MNDTRSVKRPAPLALSNWPVRVKVLAI
MSMEG_1637|M.smegmatis_MC2_155 ------------------------------------------MSRKVLAI
TH_3044|M.thermoresistible__bu MTVFSQLRKSDGTNRD-----VEPPAPDPIKKPSRWALTNWPVRWKVFAI
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1165|M.marinum_M AVVPLLLAMVLGGLRIHGGMANSSGLRLADARADVIPAITKYMSALDVAL
MUL_2850|M.ulcerans_Agy99 AVVPLLLAMVLGGLRIHGGMANSSGLRLADARADVIPAITKYMSALDVAL
Mb3400c|M.bovis_AF2122/97 ALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAV
Rv3365c|M.tuberculosis_H37Rv ALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAV
MAV_4331|M.avium_104 VLVPLMLATVFGVLRIHGAMANAAGLRLAAARADVVPAITKYMSALDVAL
Mflv_4889|M.gilvum_PYR-GCK VTVPLVLACVFGGLRISASTVEARELAHAADRAQMVPAVVDYMAALQNAM
Mvan_1536|M.vanbaalenii_PYR-1 VVVPLLLACVFGGLRIYSSATEAAELRHAAQRADMVPAVVDYMAALEAAM
MSMEG_1637|M.smegmatis_MC2_155 VLVPLILAATFGGLRIYASVTEAADLRLAADRAELIPDINNYMAALEGVL
TH_3044|M.thermoresistible__bu VLVPLLLIATFAGLRVYSGVAENAELRRAVDRAEVIPPVVDYMAALEEAM
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1165|M.marinum_M LASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSVLNGGQAL
MUL_2850|M.ulcerans_Agy99 LASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSVLNGGQAL
Mb3400c|M.bovis_AF2122/97 LASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQAL
Rv3365c|M.tuberculosis_H37Rv LASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQAL
MAV_4331|M.avium_104 LAGSAGRDAEGAKKNYEARKNELQTRLGDTDVTDDVRAGVNNLLDTGQML
Mflv_4889|M.gilvum_PYR-GCK VTAGGGGNPAAALGEFDFRKAELSRVLEGADVDDSVRLATNTLLEYGQNL
Mvan_1536|M.vanbaalenii_PYR-1 VTATEGGDARQALTVFESRRTGLQHLLDVTPVDDGVRLATNTLIDFGQNL
MSMEG_1637|M.smegmatis_MC2_155 VASSGAGDGQAALATFDSRKSELQQRVDSTDVLGDVREAVGTMLDKGQTL
TH_3044|M.thermoresistible__bu VAATTGRETQPALARFDERKTELRERAEQGEIVPDVRAAVDTLLDGGQDL
MLBr_00175|M.leprae_Br4923 -----------------MVRFAWRRRAS-------LRATSS-LSLRWR--
MAB_1077|M.abscessus_ATCC_1997 ---------------MSTLRMPRRMRDSSTAIFTPLRATSSSVSLRWR--
: :* . : :
MMAR_1165|M.marinum_M LDQTLANTISLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRA
MUL_2850|M.ulcerans_Agy99 LDQTLANTSSLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRA
Mb3400c|M.bovis_AF2122/97 LDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRA
Rv3365c|M.tuberculosis_H37Rv LDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRA
MAV_4331|M.avium_104 VNKVAEGSLGLRERVTFYAPILLTAENVINASVRVDDERIRAQAQGLSRA
Mflv_4889|M.gilvum_PYR-GCK LDRIGAAEMNLRTQVMTFGPLLITAQTALTGSVGSDEDSVRTEADVLSRA
Mvan_1536|M.vanbaalenii_PYR-1 IDKISADAIDLRTRVMTYAPLLITSETAITGLVGADDERVRSDADTLSRA
MSMEG_1637|M.smegmatis_MC2_155 VDASMANTVGLRQRILDYAPLLLTAEAAVTGSTHSADQRVQTEAEALGRA
TH_3044|M.thermoresistible__bu INKVMSNVVDLRQRVTAYAPLLLTAETAITGSARDDAPGVQRKAEALSRA
MLBr_00175|M.leprae_Br4923 VMLLAMSMVAMVVVLMAFAVYVVISAALYS--------DIDNQLQSRAQL
MAB_1077|M.abscessus_ATCC_1997 VMLLAMSMVAMVVVLMAVASYLLVSTALYR--------DVDKQLNDRANL
: : : :: : : . : ..
MMAR_1165|M.marinum_M VGARGQMTLQEILVTRGAEAPEAQLRNSMITLAGTEPSTLFGMTEVLGVG
MUL_2850|M.ulcerans_Agy99 VGARGQMTLQEILVTRGVEAPEAQLRNSMITLAGTGPSTLFGMTEVLGVG
Mb3400c|M.bovis_AF2122/97 VGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAG
Rv3365c|M.tuberculosis_H37Rv VGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAG
MAV_4331|M.avium_104 VGARGQMTMQKILVTRGAELPEPQLRTSMATLAGTEPSTLFGMSEVLGAG
Mflv_4889|M.gilvum_PYR-GCK VGARGQMAMQDMLVTRGGELPEPLLRSAMVTLAGTEPATVTAMGTFLGGA
Mvan_1536|M.vanbaalenii_PYR-1 VGARGQMAMQRMLVNSGAELPEPLLRSAMVTIAGTEPATVTAMGGYLGGA
MSMEG_1637|M.smegmatis_MC2_155 IGARGQMTIQEMMVNRGAEEPEPVLRKSMITMAGTEPSTVAALTKVLGSA
TH_3044|M.thermoresistible__bu VGARGQMTMQEMSVTSGGYLPEPELRTSLITLAGTEPSTINGMIAYLGND
MLBr_00175|M.leprae_Br4923 LIASGSLAADPGKAIEGTAYS---DVNAMLVNPGHSIYTANQPGQTLPVG
MAB_1077|M.abscessus_ATCC_1997 LIGSGLLSVDPRRAIEGTAYSA--DVNAKLIFPGLITFSATQQGQTIPYG
: . * :: : . * . .: .* : :
MMAR_1165|M.marinum_M SPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQSIQITRGIAEQVINDAT
MUL_2850|M.ulcerans_Agy99 SPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQSIQITRGIAEQVINDAT
Mb3400c|M.bovis_AF2122/97 SPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTT
Rv3365c|M.tuberculosis_H37Rv SPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTT
MAV_4331|M.avium_104 SPEAKTLQQQMVSRMAIMSDPASVLVDNPDLLRSIQTTDDIADQVIKNTT
Mflv_4889|M.gilvum_PYR-GCK SDRADALRSQMVRRMSLLSDPAVVLVGNPELLMSQKITADIAQSLINRIA
Mvan_1536|M.vanbaalenii_PYR-1 TEQASTLRSEMVKRMALLSEPTTALVGNPELLASQKITGDIAAGLIAQTT
MSMEG_1637|M.smegmatis_MC2_155 SDDATTLRDEMVKRMAIMANPGIPLVGNPVLLESLENTRKIAEQIITDNT
TH_3044|M.thermoresistible__bu SQQAATLRTEMVRRMSMMSDPAVPLAANPELLGSQQVTRSVADAMIAELA
MLBr_00175|M.leprae_Br4923 TAEKAVIRGELFMSQRTASD-----------------QRILAIHLPNDSS
MAB_1077|M.abscessus_ATCC_1997 TPEQAVTRGDLQQSLRTVNH-----------------QRVLALRLDNGST
: : :: . :* : :
MMAR_1165|M.marinum_M ESVTKAVQARASARRDAAIRDTVFVLGAILVAVVVVLLVARALVRPLRQL
MUL_2850|M.ulcerans_Agy99 ESVTKAVQARASARRDAAIRDTVLVLGAILVAVVVVLLVARALVRPLRQL
Mb3400c|M.bovis_AF2122/97 EAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVL
Rv3365c|M.tuberculosis_H37Rv EAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVL
MAV_4331|M.avium_104 ASVTKSVHAQAAERRNSAILDTALVLAAIVIALAVVLLVARALVRPLRTL
Mflv_4889|M.gilvum_PYR-GCK DEIPARVSRQADDARTAAIRDSVLVGAAILVALILVLWVARSLVRPLRTL
Mvan_1536|M.vanbaalenii_PYR-1 EDIPAAVARQADDARTAAIRDAALVGAAILVALILVTLVARSMVRPLRTL
MSMEG_1637|M.smegmatis_MC2_155 SAIPAAVEAEAADARNDAIRDSVLVALAVISALVVVLLVARSLVRPLRTL
TH_3044|M.thermoresistible__bu TTIPDEVRQAADDQRTAAIRDTVLVLLAIAVAAVVVLLVARSLVRPLRTL
MLBr_00175|M.leprae_Br4923 LLISKSLRPTEAVMTKLRWVLLIVGSLGVAVAAVAGGMVTRAGLRPVGRL
MAB_1077|M.abscessus_ATCC_1997 LIMAKSLDPTDTVLRRLGWVLLIVGGVGVAVAAAAGAMVAGTGLRPVARL
:. : . .: * *: : : *: *
MMAR_1165|M.marinum_M RDGALKVAHTDLEGEIAKVRAG-AEPIPEPLPVYTTEEIGQVAHAVDELH
MUL_2850|M.ulcerans_Agy99 RDGALKVAHTDLEGEIAKVREG-AEPIPEPLPVYTTEEIGQVAHAVDELH
Mb3400c|M.bovis_AF2122/97 RDGALKVAHTDLDGEIAAVRAG-DEPIPEPLAVYTTEEIGQVAHAVDELH
Rv3365c|M.tuberculosis_H37Rv RDGALKVAHTDLDGEIAAVRAG-DEPIPEPLAVYTTEEIGQVAHAVDELH
MAV_4331|M.avium_104 RDGALKVAHTDLEEEIAHVKAGGAEPIPAPLPVYTTEEIGQVAHAVDELH
Mflv_4889|M.gilvum_PYR-GCK RDSALRVAHDDLGREVERVRDDGKEFAVDPIPVHTTEEVGQVAHAVDELH
Mvan_1536|M.vanbaalenii_PYR-1 RDSALKVAHEDLPREVEHVRSDGKEFPVQPIPVHTTEEVGQVAHAVDELH
MSMEG_1637|M.smegmatis_MC2_155 RDGALKVAHEDLAKEIERVRAGGEPGPITPLPVYTSEEVGQVAHAVDELH
TH_3044|M.thermoresistible__bu RDSALKVAHGDLARELDQVRETGELPEVEPIAVHTTEEIGQVAHAVDELH
MLBr_00175|M.leprae_Br4923 TEAAERVARTD---------------DLRPIPVFGSDELARLTEAFNLML
MAB_1077|M.abscessus_ATCC_1997 TDAAERVARTD---------------DLRPIAVTGSDELARLTISFNTML
:.* :**: * *:.* ::*:.::: :.: :
MMAR_1165|M.marinum_M AQVLVLAGDEARLRSLVNDMFETMSRRSRSLVDQQLSLIDGLERNEEDPE
MUL_2850|M.ulcerans_Agy99 AQVLVLAGDEARLRSLVNDMFETMSRRSRSLVDQQLSLIDGLERNEEDPD
Mb3400c|M.bovis_AF2122/97 TRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPA
Rv3365c|M.tuberculosis_H37Rv TRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPA
MAV_4331|M.avium_104 TQALLLAGDEARLRLLVNDMFETMSRRSRSLVDQQLALIDRLERNEDNPE
Mflv_4889|M.gilvum_PYR-GCK QQALVLAGAQARLQLQVTDMFETLSRRNRSLVEQQLSLIDGLERDEEDPD
Mvan_1536|M.vanbaalenii_PYR-1 QQAVMLAGEQARLQLQVTDMFETLSRRNRSLVDQQLSLIDRLERDEEDPD
MSMEG_1637|M.smegmatis_MC2_155 EQAVFLAGEQAQLQLQVADMFETLSRRSRSLVDQQLSLIDELERNEDDPQ
TH_3044|M.thermoresistible__bu EQAVFLAGEQTRLQMQISDMFETLSRRSRSLVDQQLALIDQLERNEEDPQ
MLBr_00175|M.leprae_Br4923 RALAESRERQARLVTDAGHELRTPLTSLRTNVELLIASMAPEAPRLPDQE
MAB_1077|M.abscessus_ATCC_1997 RALAESRDRQARLVTDAGHELRTPLTSLRTNTELLMAAMQPGAPRLPDEE
:::* . :.* *: .: :: : :
MMAR_1165|M.marinum_M RLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVISAAVSE
MUL_2850|M.ulcerans_Agy99 RLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVISAAVSE
Mb3400c|M.bovis_AF2122/97 RLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSE
Rv3365c|M.tuberculosis_H37Rv RLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSE
MAV_4331|M.avium_104 RLDNLFRLDHLAARLRRNSANLLVLAGAKLARDQRDPVPLATVINAAVSE
Mflv_4889|M.gilvum_PYR-GCK RLQSLFQLDHLAARMRRNGANLLVLAGARISHDRAEPVAVAAIVNAAASE
Mvan_1536|M.vanbaalenii_PYR-1 RLESLFRLDHLAARMRRNGSNLMVLAGAQISRERAESVPVTALVNAAASE
MSMEG_1637|M.smegmatis_MC2_155 RLNSLFRLDHLAARMRRNGANLLVLSGAKVTREKSEPVAVATVINAAASE
TH_3044|M.thermoresistible__bu RLQNLFRLDHLAARMRRNGANLLVLAGAKVPREQAAPMPVASLIHAAASE
MLBr_00175|M.leprae_Br4923 MADLRADVLAQIEELSTLVGDLVDLTRDDAGQVVHEPIDMSEVLYRSLER
MAB_1077|M.abscessus_ATCC_1997 MQALQQDVIAQIEELSTLVGDLVDLARGDGADIVHEPVDMVEVVEGTLER
: .: .:*: *: .: : :: : ..
MMAR_1165|M.marinum_M VEDYRRVETGGVADC--TVIGAAAGAVIHLLAELIDNALNYSPPTAPVRV
MUL_2850|M.ulcerans_Agy99 VEDYRRVETGGVADC--TVIGAAAGAVIHLLAELIDNALNYSPPTAPVRV
Mb3400c|M.bovis_AF2122/97 VEDYRRVDIARVPDC--AVVGAAAGGVIHLLAELIDNALRYSSPTTPVRV
Rv3365c|M.tuberculosis_H37Rv VEDYRRVDIARVPDC--AVVGAAAGGVIHLLAELIDNALRYSSPTTPVRV
MAV_4331|M.avium_104 VEDYRRVEIAGLPEC--SLLGAAAGGAIHLFAELIDNALRYSPPTTSARV
Mflv_4889|M.gilvum_PYR-GCK VEEYPRIVTGDLPDS--EVAASAAGDLVHLLAELLDNGLRYSPPHTQVRV
Mvan_1536|M.vanbaalenii_PYR-1 VEDYTRIVTTGLPDG--EVDGVVAGDLVHLLAELLDNALRYSPPTTEVRV
MSMEG_1637|M.smegmatis_MC2_155 VEDYTRVVTSDVADA--DVVGSAAGDLIHLLAELLDNALRYSPPTSQVRV
TH_3044|M.thermoresistible__bu VEDYTRIVMTTVPDS--EVHGSVAGDLVHILAELLDNALRYSPPTAQVRV
MLBr_00175|M.leprae_Br4923 VRRRRNDIHFDVQAIGWQIYGDAAG-LSRAVLNLMDNAAKWSPSGGRVVV
MAB_1077|M.abscessus_ATCC_1997 VRRRRNDIEFDVVMQPWQVYGDAAG-LSRAVLNLLDNAAKWSPSGTAVSV
*. . : : . .** : . :*:**. .:*.. . *
MMAR_1165|M.marinum_M SAVRGSEGGVLLRIADSGLGMTESDRRMANMRLHAGVEVTP----ANARH
MUL_2850|M.ulcerans_Agy99 SAVRGSEGGVLLRIADSGLGMTESDRRMANMRLHSGGEVTP----ANARH
Mb3400c|M.bovis_AF2122/97 AAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTP----DSARH
Rv3365c|M.tuberculosis_H37Rv AAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTP----DSARH
MAV_4331|M.avium_104 SASRGGDGGVVVRIADSGLGMNDADRRIANMRLQAGGDANPDPHPENARH
Mflv_4889|M.gilvum_PYR-GCK SAVPTDNNGLVIEVSDTGLGMTEADLRVANMRLESGGEVNP----YTARH
Mvan_1536|M.vanbaalenii_PYR-1 SAVPTGNNGLVIEVSDTGLGMTESDLRVANTRLESGGEVNP----YTARH
MSMEG_1637|M.smegmatis_MC2_155 SAVFAGNGALVIEVADVGLGMTESDLRVANIRLKSGGEVNP----YTARH
TH_3044|M.thermoresistible__bu SAGHADTGALVIEVSDAGLGMSESDLRMANARLESXX-------------
MLBr_00175|M.leprae_Br4923 TMRQFDPSHVELVVSDYGPGIPPQERRLVFERFYRSTTARS----LPGSG
MAB_1077|M.abscessus_ATCC_1997 RLAQVDAAHAELVISDHGPGIPPAERDLVFERFYRATPARG----MPGSG
. : ::* * *: : :. *:
MMAR_1165|M.marinum_M MGLFVVGRLAARHGIRVGLRGPST-----GEAGGGTTAEVYLPRTVLVDG
MUL_2850|M.ulcerans_Agy99 MGLFVVGRLAARHGIRVGLRGPST-----GEAGGGTTAEVYLPRTVLVDG
Mb3400c|M.bovis_AF2122/97 MGLFVVGRLAGRHGIRVGLRGPVT-----GEQGTGTTAEVYLPLAVLEG-
Rv3365c|M.tuberculosis_H37Rv MGLFVVGRLAGRHGIRVGLRGPVT-----GEQGTGTTAEVYLPLAVLEG-
MAV_4331|M.avium_104 LGLFVVGRIAAWHGMRVGLRGPAA-----NESGSGTTAEVYLPPTVLAG-
Mflv_4889|M.gilvum_PYR-GCK MGLFVVSRLAAQHGLVARLRSTVA-----GQPDSGTTAGVYIPARLLVR-
Mvan_1536|M.vanbaalenii_PYR-1 MGLFVVGRLAASHGLVVRLRSTVA-----GEPDSGTTAGVYIPARLLIH-
MSMEG_1637|M.smegmatis_MC2_155 MGLFVVGRLADQHGLVVRLRSTIP-----DEPGSGTTAGVYVPAQLLVT-
TH_3044|M.thermoresistible__bu ----XAGRRCPGRAPTPRVGCRAH-----TCPHCGSRA---PPAQ-----
MLBr_00175|M.leprae_Br4923 LGLAIVKQVVINHGGLLRVEDTAP-----GVQPPGTSIYVLLPG------
MAB_1077|M.abscessus_ATCC_1997 LGLAIVKQVVLKHGGAIKVEETDPGAVIDGEPAPGTSMHVLLPG------
. : :. : *: *
MMAR_1165|M.marinum_M QRPGPAAGQPPQRRAVV---VRPPSSEPAPAPDAAGSAPTGDSTAVPP--
MUL_2850|M.ulcerans_Agy99 QRPGSAAGQPPQRSAFV---VRPPSSEPAPAPDAAGSAPTGDSTAVPP--
Mb3400c|M.bovis_AF2122/97 ----TAPAQPPKPRVFA---IKPPCPEPAAA------DPTDVPAAIGP--
Rv3365c|M.tuberculosis_H37Rv ----TAPAQPPKPRVFA---IKPPCPEPAAA------DPTDVPAAIGP--
MAV_4331|M.avium_104 -RVVAEPSGPRHIRAVSSPSAKLASAIAAPAEEGGRHDGTQQPAARGTRN
Mflv_4889|M.gilvum_PYR-GCK ---RA----APPVQARD---VRPAAPAPAP-------TPAPAPAP-PPPP
Mvan_1536|M.vanbaalenii_PYR-1 ---TA----PAQYGGRD---DEPVPADAHAGIATALALEVPAGVPREAPA
MSMEG_1637|M.smegmatis_MC2_155 ---EAGTAGTPAFDQFD---AQPEDAATAPGHPTGYPNVVSLDTRFVTTG
TH_3044|M.thermoresistible__bu ---------PPGSEQQG---GEPPVEHLTVG-------------------
MLBr_00175|M.leprae_Br4923 ---------------------RPMPVSAYS--------------------
MAB_1077|M.abscessus_ATCC_1997 ---------------------RPGPIVR----------------------
.
MMAR_1165|M.marinum_M -----LPPVSLLPRRNPGSSGIADVPG--QQPEQQQPPRRRRELKTPWWE
MUL_2850|M.ulcerans_Agy99 -----LPPVSLLPRRNPGSSGIADVPG--QQPEQQQPPRRRRELKTPWWE
Mb3400c|M.bovis_AF2122/97 -----LPPVTLLPRRTPGSSGIADVP---AQPMQQ----RRRELKTPWWE
Rv3365c|M.tuberculosis_H37Rv -----LPPVTLLPRRTPGSSGIADVP---AQPMQQ----RRRELKTPWWE
MAV_4331|M.avium_104 TGDASTPPVTLLPRRNPGSSGIADVAAVPAPPAEPQPRRQRRELATPWWE
Mflv_4889|M.gilvum_PYR-GCK APVVP--PADVLPQRRP---------------EPPPPVEPP---------
Mvan_1536|M.vanbaalenii_PYR-1 AAAGP--ATDLLPQRRPGASGIVETP----AETPVAPIETPVATSVAVVT
MSMEG_1637|M.smegmatis_MC2_155 SEHDDDLAAGLLPQRNPGASGISEMPGVFAEPEPAAEVSGDAQGEWPQQW
TH_3044|M.thermoresistible__bu ------IADGVHQRAQP---------------QHPAPVTGER--------
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1165|M.marinum_M TA----------QPAGQPEQAAPQ----QSDTAAFFARRSPAAGAGPDEP
MUL_2850|M.ulcerans_Agy99 TA----------QPAGRPEQAAPQ----QSDTAAFFARRSPAAGAGPDEP
Mb3400c|M.bovis_AF2122/97 DR----------FQQEPKQPPAP-------------------------EP
Rv3365c|M.tuberculosis_H37Rv DR----------FQQEPKQPPAP-------------------------EP
MAV_4331|M.avium_104 ASPAPRPAPEPQQPAPEPQQPAPRPARAASDTSAFFAARPRTETPPETPP
Mflv_4889|M.gilvum_PYR-GCK -------------PPVETPP------------------------PVETP-
Mvan_1536|M.vanbaalenii_PYR-1 PAATPVAAVTPVAPPVETPPARSEVAAFFSPRPQ----------PTETNG
MSMEG_1637|M.smegmatis_MC2_155 PAPQEAAAPEEVAPQANGRPTDTSSFFASRAQAAGGTQNGAQVNGVHLDG
TH_3044|M.thermoresistible__bu --------------------------------------------------
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1165|M.marinum_M APSVKPGP-----------------PSALADPARDDSIYQKMLSEMTSDP
MUL_2850|M.ulcerans_Agy99 APSVKPGP-----------------PSVPADPVRDDSIYQKMLSEMTSDP
Mb3400c|M.bovis_AF2122/97 RPAPPPAK-----------------PAPPAGPVDDDVIYRRMLSEMVGDP
Rv3365c|M.tuberculosis_H37Rv RPAPPPAK-----------------PAPPAGPVDDDVIYRRMLSEMVGDP
MAV_4331|M.avium_104 EAPPKPAPKPK--------PEASIPPAASTGPADDDVIYRRMLSEMLGDP
Mflv_4889|M.gilvum_PYR-GCK --RPGHAD-----------------------IDHDDTIYQKMLSEWLVDP
Mvan_1536|M.vanbaalenii_PYR-1 HARHAAAD-----------------------SDPDDAIYQKMLSEWLVDP
MSMEG_1637|M.smegmatis_MC2_155 AHTNGAANGTADSFTGFFGSSDDQLDQREPAGDPGDSIYQSMVSEFAIDP
TH_3044|M.thermoresistible__bu --------------------------------------FGGLDVQFAVEG
MLBr_00175|M.leprae_Br4923 -----------------------------------TLADQDMGEANFQDK
MAB_1077|M.abscessus_ATCC_1997 ---------------------------------------PNMGDTAGRRN
:
MMAR_1165|M.marinum_M HELANSADLDWRSVWDRGWSAAAEAQDTPVQSR-TDHGLPVRTPGARLVP
MUL_2850|M.ulcerans_Agy99 HELANSADLDWRSVWDRGWSAAAEAQETPVQSR-TDHGLPVRTPGARLVP
Mb3400c|M.bovis_AF2122/97 HELAHSPDLDWKSVWDHGWSAAAEAADKPVQSR-TDYGLPVREPGARLVP
Rv3365c|M.tuberculosis_H37Rv HELAHSPDLDWKSVWDHGWSAAAEAADKPVQSR-TDYGLPVREPGARLVP
MAV_4331|M.avium_104 HDLVNSPDLDWQSVWDRGWTLAAAAEDKPVESHTTDHGLPVRTPGARLVP
Mflv_4889|M.gilvum_PYR-GCK HELSHSSDLNWKSVWDNGWSAAEAADAAPVRHR-TPEGLPVRRPGARLIP
Mvan_1536|M.vanbaalenii_PYR-1 HELSHSTDLNWKSVWDHGWSAAEAAEAAPVLDH-TAEGLPVRRPGARLVP
MSMEG_1637|M.smegmatis_MC2_155 TTHARSADLDWQTVWEKGWSVAAAAQDAPVDRH-TEEGLPMRTPGARLVP
TH_3044|M.thermoresistible__bu VALVHR----------AGVVAGLPAEHGDQVGQ-QAGGLRQRQPDG----
MLBr_00175|M.leprae_Br4923 IGPAVQVSGKSANFRDSAHVISVDYQSARAR-------------------
MAB_1077|M.abscessus_ATCC_1997 SGP-------------NAREISVDSQSVPAAWRPS---------------
. .
MMAR_1165|M.marinum_M GAADSDEPNQDEADRPPASD--------------------RGLPPDQPAQ
MUL_2850|M.ulcerans_Agy99 GAADSDEPTQDEADRPPASD--------------------RGLPPDQPAQ
Mb3400c|M.bovis_AF2122/97 GAAVPEGPDREHPGAALASN--------------------GGLHPGRAPR
Rv3365c|M.tuberculosis_H37Rv GAAVPEGPDREHPGAALASN--------------------GGLHPGRAPR
MAV_4331|M.avium_104 GGAHG---AAAEPDDEPGLN--------------------GRSPAPRRPQ
Mflv_4889|M.gilvum_PYR-GCK G------------------------------------------HADTENG
Mvan_1536|M.vanbaalenii_PYR-1 G------------------------------------------HANGEP-
MSMEG_1637|M.smegmatis_MC2_155 GGVAAAAGRTNGANGHHHSDLNGGVNGEIHGNDNGAEAVASANEADNGMF
TH_3044|M.thermoresistible__bu --------------------------------------------------
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1165|M.marinum_M HTAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
MUL_2850|M.ulcerans_Agy99 HTAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
Mb3400c|M.bovis_AF2122/97 HAAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
Rv3365c|M.tuberculosis_H37Rv HAAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
MAV_4331|M.avium_104 HAAVARDPEAVRASFSSHFGGVRTGRSHARESSEGPDQQ
Mflv_4889|M.gilvum_PYR-GCK HPLPVRDPDAVRASLGGHFGGVHAGRRHAREAAGDDR--
Mvan_1536|M.vanbaalenii_PYR-1 VASAGRDPEAVRNSIGSHFGGVHAGRLRAQETGGADFP-
MSMEG_1637|M.smegmatis_MC2_155 AAFKPRDPEAVRASISSHFGGVHAGRSHARETRGTDNE-
TH_3044|M.thermoresistible__bu -------VPAVDQPLP-------AGT-------------
MLBr_00175|M.leprae_Br4923 ---------------------------------------
MAB_1077|M.abscessus_ATCC_1997 ---------------------------------------