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M. ulcerans Agy99 MUL_2850 (-)

annotation: putative regultory protein
coordinates: 3176458 - 3179193
length: 911

TMFARLTTPVEAAPGAPVASGAESAPPKRPPAWSLGNWPVGWKVVAIAVVPLLLAMVLGGLRIHGGMANS
SGLRLADARADVIPAITKYMSALDVALLASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSV
LNGGQALLDQTLANTSSLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRAVGARGQMTLQEIL
VTRGVEAPEAQLRNSMITLAGTGPSTLFGMTEVLGVGSPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQ
SIQITRGIAEQVINDATESVTKAVQARASARRDAAIRDTVLVLGAILVAVVVVLLVARALVRPLRQLRDG
ALKVAHTDLEGEIAKVREGAEPIPEPLPVYTTEEIGQVAHAVDELHAQVLVLAGDEARLRSLVNDMFETM
SRRSRSLVDQQLSLIDGLERNEEDPDRLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVI
SAAVSEVEDYRRVETGGVADCTVIGAAAGAVIHLLAELIDNALNYSPPTAPVRVSAVRGSEGGVLLRIAD
SGLGMTESDRRMANMRLHSGGEVTPANARHMGLFVVGRLAARHGIRVGLRGPSTGEAGGGTTAEVYLPRT
VLVDGQRPGSAAGQPPQRSAFVVRPPSSEPAPAPDAAGSAPTGDSTAVPPLPPVSLLPRRNPGSSGIADV
PGQQPEQQQPPRRRRELKTPWWETAQPAGRPEQAAPQQSDTAAFFARRSPAAGAGPDEPAPSVKPGPPSV
PADPVRDDSIYQKMLSEMTSDPHELANSADLDWRSVWDRGWSAAAEAQETPVQSRTDHGLPVRTPGARLV
PGAADSDEPTQDEADRPPASDRGLPPDQPAQHTAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2850--100% (911)putative regultory protein
M. ulcerans Agy99MUL_4700mprB9e-1522.38% (478) two component sensor kinase MprB
M. ulcerans Agy99MUL_4559senX34e-0826.09% (368) two component sensor histidine kinase SenX3

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3400c-0.068.71% (914) hypothetical protein Mb3400c
M. gilvum PYR-GCKMflv_4889-0.048.98% (880) integral membrane sensor signal transduction histidine kinase
M. tuberculosis H37RvRv3365c-0.068.71% (914) hypothetical protein Rv3365c
M. leprae Br4923MLBr_00175-2e-1323.29% (365) putative two-component system sensor kinase
M. abscessus ATCC 19977MAB_1077-2e-1023.01% (365) two component sensor kinase MprB
M. marinum MMMAR_1165-0.098.02% (911) putative regultory protein
M. avium 104MAV_4331-0.064.05% (954) hypothetical protein MAV_4331
M. smegmatis MC2 155MSMEG_1637-0.051.03% (923) periplasmic sensor signal transduction histidine kinase
M. thermoresistible (build 8)TH_3044-1e-16955.04% (585) PUTATIVE integral membrane sensor signal transduction histidine
M. vanbaalenii PYR-1Mvan_1536-0.049.89% (890) integral membrane sensor signal transduction histidine kinase

CLUSTAL 2.0.9 multiple sequence alignment


MUL_2850|M.ulcerans_Agy99           MTMFARLTTPVEAAPG--APVASGAESAPPKRPPAWSLGNWPVGWKVVAI
MMAR_1165|M.marinum_M               MTMFARPTTPVEAAPG--APVASGAESAPPKRPPAWSLGNWPVGWKVVAI
Mb3400c|M.bovis_AF2122/97           MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTI
Rv3365c|M.tuberculosis_H37Rv        MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTI
MAV_4331|M.avium_104                MTMFSRPAEPAAAEAP--GPAPLGGGAVPAKRPPAWSLSNWPVRWKVLAI
Mflv_4889|M.gilvum_PYR-GCK          ----------------------MARSLRPDQRPSRWAPPNWPVRVKVLAL
Mvan_1536|M.vanbaalenii_PYR-1       -----------------------MNDTRSVKRPAPLALSNWPVRVKVLAI
MSMEG_1637|M.smegmatis_MC2_155      ------------------------------------------MSRKVLAI
TH_3044|M.thermoresistible__bu      MTVFSQLRKSDGTNRD-----VEPPAPDPIKKPSRWALTNWPVRWKVFAI
MLBr_00175|M.leprae_Br4923          --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MUL_2850|M.ulcerans_Agy99           AVVPLLLAMVLGGLRIHGGMANSSGLRLADARADVIPAITKYMSALDVAL
MMAR_1165|M.marinum_M               AVVPLLLAMVLGGLRIHGGMANSSGLRLADARADVIPAITKYMSALDVAL
Mb3400c|M.bovis_AF2122/97           ALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAV
Rv3365c|M.tuberculosis_H37Rv        ALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAV
MAV_4331|M.avium_104                VLVPLMLATVFGVLRIHGAMANAAGLRLAAARADVVPAITKYMSALDVAL
Mflv_4889|M.gilvum_PYR-GCK          VTVPLVLACVFGGLRISASTVEARELAHAADRAQMVPAVVDYMAALQNAM
Mvan_1536|M.vanbaalenii_PYR-1       VVVPLLLACVFGGLRIYSSATEAAELRHAAQRADMVPAVVDYMAALEAAM
MSMEG_1637|M.smegmatis_MC2_155      VLVPLILAATFGGLRIYASVTEAADLRLAADRAELIPDINNYMAALEGVL
TH_3044|M.thermoresistible__bu      VLVPLLLIATFAGLRVYSGVAENAELRRAVDRAEVIPPVVDYMAALEEAM
MLBr_00175|M.leprae_Br4923          --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MUL_2850|M.ulcerans_Agy99           LASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSVLNGGQAL
MMAR_1165|M.marinum_M               LASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSVLNGGQAL
Mb3400c|M.bovis_AF2122/97           LASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQAL
Rv3365c|M.tuberculosis_H37Rv        LASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQAL
MAV_4331|M.avium_104                LAGSAGRDAEGAKKNYEARKNELQTRLGDTDVTDDVRAGVNNLLDTGQML
Mflv_4889|M.gilvum_PYR-GCK          VTAGGGGNPAAALGEFDFRKAELSRVLEGADVDDSVRLATNTLLEYGQNL
Mvan_1536|M.vanbaalenii_PYR-1       VTATEGGDARQALTVFESRRTGLQHLLDVTPVDDGVRLATNTLIDFGQNL
MSMEG_1637|M.smegmatis_MC2_155      VASSGAGDGQAALATFDSRKSELQQRVDSTDVLGDVREAVGTMLDKGQTL
TH_3044|M.thermoresistible__bu      VAATTGRETQPALARFDERKTELRERAEQGEIVPDVRAAVDTLLDGGQDL
MLBr_00175|M.leprae_Br4923          -----------------MVRFAWRRRAS-------LRATSS-LSLRWR--
MAB_1077|M.abscessus_ATCC_1997      ---------------MSTLRMPRRMRDSSTAIFTPLRATSSSVSLRWR--
                                                       :               :*   . :    :  

MUL_2850|M.ulcerans_Agy99           LDQTLANTSSLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRA
MMAR_1165|M.marinum_M               LDQTLANTISLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRA
Mb3400c|M.bovis_AF2122/97           LDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRA
Rv3365c|M.tuberculosis_H37Rv        LDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRA
MAV_4331|M.avium_104                VNKVAEGSLGLRERVTFYAPILLTAENVINASVRVDDERIRAQAQGLSRA
Mflv_4889|M.gilvum_PYR-GCK          LDRIGAAEMNLRTQVMTFGPLLITAQTALTGSVGSDEDSVRTEADVLSRA
Mvan_1536|M.vanbaalenii_PYR-1       IDKISADAIDLRTRVMTYAPLLITSETAITGLVGADDERVRSDADTLSRA
MSMEG_1637|M.smegmatis_MC2_155      VDASMANTVGLRQRILDYAPLLLTAEAAVTGSTHSADQRVQTEAEALGRA
TH_3044|M.thermoresistible__bu      INKVMSNVVDLRQRVTAYAPLLLTAETAITGSARDDAPGVQRKAEALSRA
MLBr_00175|M.leprae_Br4923          VMLLAMSMVAMVVVLMAFAVYVVISAALYS--------DIDNQLQSRAQL
MAB_1077|M.abscessus_ATCC_1997      VMLLAMSMVAMVVVLMAVASYLLVSTALYR--------DVDKQLNDRANL
                                    :         :   :      :: :              :  . :  .. 

MUL_2850|M.ulcerans_Agy99           VGARGQMTLQEILVTRGVEAPEAQLRNSMITLAGTGPSTLFGMTEVLGVG
MMAR_1165|M.marinum_M               VGARGQMTLQEILVTRGAEAPEAQLRNSMITLAGTEPSTLFGMTEVLGVG
Mb3400c|M.bovis_AF2122/97           VGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAG
Rv3365c|M.tuberculosis_H37Rv        VGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAG
MAV_4331|M.avium_104                VGARGQMTMQKILVTRGAELPEPQLRTSMATLAGTEPSTLFGMSEVLGAG
Mflv_4889|M.gilvum_PYR-GCK          VGARGQMAMQDMLVTRGGELPEPLLRSAMVTLAGTEPATVTAMGTFLGGA
Mvan_1536|M.vanbaalenii_PYR-1       VGARGQMAMQRMLVNSGAELPEPLLRSAMVTIAGTEPATVTAMGGYLGGA
MSMEG_1637|M.smegmatis_MC2_155      IGARGQMTIQEMMVNRGAEEPEPVLRKSMITMAGTEPSTVAALTKVLGSA
TH_3044|M.thermoresistible__bu      VGARGQMTMQEMSVTSGGYLPEPELRTSLITLAGTEPSTINGMIAYLGND
MLBr_00175|M.leprae_Br4923          LIASGSLAADPGKAIEGTAYS---DVNAMLVNPGHSIYTANQPGQTLPVG
MAB_1077|M.abscessus_ATCC_1997      LIGSGLLSVDPRRAIEGTAYSA--DVNAKLIFPGLITFSATQQGQTIPYG
                                    : . * :: :   .  *   .     .:    .*    :       :   

MUL_2850|M.ulcerans_Agy99           SPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQSIQITRGIAEQVINDAT
MMAR_1165|M.marinum_M               SPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQSIQITRGIAEQVINDAT
Mb3400c|M.bovis_AF2122/97           SPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTT
Rv3365c|M.tuberculosis_H37Rv        SPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTT
MAV_4331|M.avium_104                SPEAKTLQQQMVSRMAIMSDPASVLVDNPDLLRSIQTTDDIADQVIKNTT
Mflv_4889|M.gilvum_PYR-GCK          SDRADALRSQMVRRMSLLSDPAVVLVGNPELLMSQKITADIAQSLINRIA
Mvan_1536|M.vanbaalenii_PYR-1       TEQASTLRSEMVKRMALLSEPTTALVGNPELLASQKITGDIAAGLIAQTT
MSMEG_1637|M.smegmatis_MC2_155      SDDATTLRDEMVKRMAIMANPGIPLVGNPVLLESLENTRKIAEQIITDNT
TH_3044|M.thermoresistible__bu      SQQAATLRTEMVRRMSMMSDPAVPLAANPELLGSQQVTRSVADAMIAELA
MLBr_00175|M.leprae_Br4923          TAEKAVIRGELFMSQRTASD-----------------QRILAIHLPNDSS
MAB_1077|M.abscessus_ATCC_1997      TPEQAVTRGDLQQSLRTVNH-----------------QRVLALRLDNGST
                                    :      : ::        .                    :*  :    :

MUL_2850|M.ulcerans_Agy99           ESVTKAVQARASARRDAAIRDTVLVLGAILVAVVVVLLVARALVRPLRQL
MMAR_1165|M.marinum_M               ESVTKAVQARASARRDAAIRDTVFVLGAILVAVVVVLLVARALVRPLRQL
Mb3400c|M.bovis_AF2122/97           EAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVL
Rv3365c|M.tuberculosis_H37Rv        EAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVL
MAV_4331|M.avium_104                ASVTKSVHAQAAERRNSAILDTALVLAAIVIALAVVLLVARALVRPLRTL
Mflv_4889|M.gilvum_PYR-GCK          DEIPARVSRQADDARTAAIRDSVLVGAAILVALILVLWVARSLVRPLRTL
Mvan_1536|M.vanbaalenii_PYR-1       EDIPAAVARQADDARTAAIRDAALVGAAILVALILVTLVARSMVRPLRTL
MSMEG_1637|M.smegmatis_MC2_155      SAIPAAVEAEAADARNDAIRDSVLVALAVISALVVVLLVARSLVRPLRTL
TH_3044|M.thermoresistible__bu      TTIPDEVRQAADDQRTAAIRDTVLVLLAIAVAAVVVLLVARSLVRPLRTL
MLBr_00175|M.leprae_Br4923          LLISKSLRPTEAVMTKLRWVLLIVGSLGVAVAAVAGGMVTRAGLRPVGRL
MAB_1077|M.abscessus_ATCC_1997      LIMAKSLDPTDTVLRRLGWVLLIVGGVGVAVAAAAGAMVAGTGLRPVARL
                                      :.  :                .   .:  *      *: : : *:  *

MUL_2850|M.ulcerans_Agy99           RDGALKVAHTDLEGEIAKVREG-AEPIPEPLPVYTTEEIGQVAHAVDELH
MMAR_1165|M.marinum_M               RDGALKVAHTDLEGEIAKVRAG-AEPIPEPLPVYTTEEIGQVAHAVDELH
Mb3400c|M.bovis_AF2122/97           RDGALKVAHTDLDGEIAAVRAG-DEPIPEPLAVYTTEEIGQVAHAVDELH
Rv3365c|M.tuberculosis_H37Rv        RDGALKVAHTDLDGEIAAVRAG-DEPIPEPLAVYTTEEIGQVAHAVDELH
MAV_4331|M.avium_104                RDGALKVAHTDLEEEIAHVKAGGAEPIPAPLPVYTTEEIGQVAHAVDELH
Mflv_4889|M.gilvum_PYR-GCK          RDSALRVAHDDLGREVERVRDDGKEFAVDPIPVHTTEEVGQVAHAVDELH
Mvan_1536|M.vanbaalenii_PYR-1       RDSALKVAHEDLPREVEHVRSDGKEFPVQPIPVHTTEEVGQVAHAVDELH
MSMEG_1637|M.smegmatis_MC2_155      RDGALKVAHEDLAKEIERVRAGGEPGPITPLPVYTSEEVGQVAHAVDELH
TH_3044|M.thermoresistible__bu      RDSALKVAHGDLARELDQVRETGELPEVEPIAVHTTEEIGQVAHAVDELH
MLBr_00175|M.leprae_Br4923          TEAAERVARTD---------------DLRPIPVFGSDELARLTEAFNLML
MAB_1077|M.abscessus_ATCC_1997      TDAAERVARTD---------------DLRPIAVTGSDELARLTISFNTML
                                     :.* :**: *                  *:.*  ::*:.::: :.: : 

MUL_2850|M.ulcerans_Agy99           AQVLVLAGDEARLRSLVNDMFETMSRRSRSLVDQQLSLIDGLERNEEDPD
MMAR_1165|M.marinum_M               AQVLVLAGDEARLRSLVNDMFETMSRRSRSLVDQQLSLIDGLERNEEDPE
Mb3400c|M.bovis_AF2122/97           TRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPA
Rv3365c|M.tuberculosis_H37Rv        TRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPA
MAV_4331|M.avium_104                TQALLLAGDEARLRLLVNDMFETMSRRSRSLVDQQLALIDRLERNEDNPE
Mflv_4889|M.gilvum_PYR-GCK          QQALVLAGAQARLQLQVTDMFETLSRRNRSLVEQQLSLIDGLERDEEDPD
Mvan_1536|M.vanbaalenii_PYR-1       QQAVMLAGEQARLQLQVTDMFETLSRRNRSLVDQQLSLIDRLERDEEDPD
MSMEG_1637|M.smegmatis_MC2_155      EQAVFLAGEQAQLQLQVADMFETLSRRSRSLVDQQLSLIDELERNEDDPQ
TH_3044|M.thermoresistible__bu      EQAVFLAGEQTRLQMQISDMFETLSRRSRSLVDQQLALIDQLERNEEDPQ
MLBr_00175|M.leprae_Br4923          RALAESRERQARLVTDAGHELRTPLTSLRTNVELLIASMAPEAPRLPDQE
MAB_1077|M.abscessus_ATCC_1997      RALAESRDRQARLVTDAGHELRTPLTSLRTNTELLMAAMQPGAPRLPDEE
                                             :::*     . :.*     *: .:  :: :        :  

MUL_2850|M.ulcerans_Agy99           RLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVISAAVSE
MMAR_1165|M.marinum_M               RLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVISAAVSE
Mb3400c|M.bovis_AF2122/97           RLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSE
Rv3365c|M.tuberculosis_H37Rv        RLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSE
MAV_4331|M.avium_104                RLDNLFRLDHLAARLRRNSANLLVLAGAKLARDQRDPVPLATVINAAVSE
Mflv_4889|M.gilvum_PYR-GCK          RLQSLFQLDHLAARMRRNGANLLVLAGARISHDRAEPVAVAAIVNAAASE
Mvan_1536|M.vanbaalenii_PYR-1       RLESLFRLDHLAARMRRNGSNLMVLAGAQISRERAESVPVTALVNAAASE
MSMEG_1637|M.smegmatis_MC2_155      RLNSLFRLDHLAARMRRNGANLLVLSGAKVTREKSEPVAVATVINAAASE
TH_3044|M.thermoresistible__bu      RLQNLFRLDHLAARMRRNGANLLVLAGAKVPREQAAPMPVASLIHAAASE
MLBr_00175|M.leprae_Br4923          MADLRADVLAQIEELSTLVGDLVDLTRDDAGQVVHEPIDMSEVLYRSLER
MAB_1077|M.abscessus_ATCC_1997      MQALQQDVIAQIEELSTLVGDLVDLARGDGADIVHEPVDMVEVVEGTLER
                                           :     .:    .:*: *:          .: :  ::  : ..

MUL_2850|M.ulcerans_Agy99           VEDYRRVETGGVADC--TVIGAAAGAVIHLLAELIDNALNYSPPTAPVRV
MMAR_1165|M.marinum_M               VEDYRRVETGGVADC--TVIGAAAGAVIHLLAELIDNALNYSPPTAPVRV
Mb3400c|M.bovis_AF2122/97           VEDYRRVDIARVPDC--AVVGAAAGGVIHLLAELIDNALRYSSPTTPVRV
Rv3365c|M.tuberculosis_H37Rv        VEDYRRVDIARVPDC--AVVGAAAGGVIHLLAELIDNALRYSSPTTPVRV
MAV_4331|M.avium_104                VEDYRRVEIAGLPEC--SLLGAAAGGAIHLFAELIDNALRYSPPTTSARV
Mflv_4889|M.gilvum_PYR-GCK          VEEYPRIVTGDLPDS--EVAASAAGDLVHLLAELLDNGLRYSPPHTQVRV
Mvan_1536|M.vanbaalenii_PYR-1       VEDYTRIVTTGLPDG--EVDGVVAGDLVHLLAELLDNALRYSPPTTEVRV
MSMEG_1637|M.smegmatis_MC2_155      VEDYTRVVTSDVADA--DVVGSAAGDLIHLLAELLDNALRYSPPTSQVRV
TH_3044|M.thermoresistible__bu      VEDYTRIVMTTVPDS--EVHGSVAGDLVHILAELLDNALRYSPPTAQVRV
MLBr_00175|M.leprae_Br4923          VRRRRNDIHFDVQAIGWQIYGDAAG-LSRAVLNLMDNAAKWSPSGGRVVV
MAB_1077|M.abscessus_ATCC_1997      VRRRRNDIEFDVVMQPWQVYGDAAG-LSRAVLNLLDNAAKWSPSGTAVSV
                                    *.   .     :      : . .**   : . :*:**. .:*..   . *

MUL_2850|M.ulcerans_Agy99           SAVRGSEGGVLLRIADSGLGMTESDRRMANMRLHSGGEVTP----ANARH
MMAR_1165|M.marinum_M               SAVRGSEGGVLLRIADSGLGMTESDRRMANMRLHAGVEVTP----ANARH
Mb3400c|M.bovis_AF2122/97           AAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTP----DSARH
Rv3365c|M.tuberculosis_H37Rv        AAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTP----DSARH
MAV_4331|M.avium_104                SASRGGDGGVVVRIADSGLGMNDADRRIANMRLQAGGDANPDPHPENARH
Mflv_4889|M.gilvum_PYR-GCK          SAVPTDNNGLVIEVSDTGLGMTEADLRVANMRLESGGEVNP----YTARH
Mvan_1536|M.vanbaalenii_PYR-1       SAVPTGNNGLVIEVSDTGLGMTESDLRVANTRLESGGEVNP----YTARH
MSMEG_1637|M.smegmatis_MC2_155      SAVFAGNGALVIEVADVGLGMTESDLRVANIRLKSGGEVNP----YTARH
TH_3044|M.thermoresistible__bu      SAGHADTGALVIEVSDAGLGMSESDLRMANARLESXX-------------
MLBr_00175|M.leprae_Br4923          TMRQFDPSHVELVVSDYGPGIPPQERRLVFERFYRSTTARS----LPGSG
MAB_1077|M.abscessus_ATCC_1997      RLAQVDAAHAELVISDHGPGIPPAERDLVFERFYRATPARG----MPGSG
                                         .     : ::* * *:   :  :.  *:                 

MUL_2850|M.ulcerans_Agy99           MGLFVVGRLAARHGIRVGLRGPST-----GEAGGGTTAEVYLPRTVLVDG
MMAR_1165|M.marinum_M               MGLFVVGRLAARHGIRVGLRGPST-----GEAGGGTTAEVYLPRTVLVDG
Mb3400c|M.bovis_AF2122/97           MGLFVVGRLAGRHGIRVGLRGPVT-----GEQGTGTTAEVYLPLAVLEG-
Rv3365c|M.tuberculosis_H37Rv        MGLFVVGRLAGRHGIRVGLRGPVT-----GEQGTGTTAEVYLPLAVLEG-
MAV_4331|M.avium_104                LGLFVVGRIAAWHGMRVGLRGPAA-----NESGSGTTAEVYLPPTVLAG-
Mflv_4889|M.gilvum_PYR-GCK          MGLFVVSRLAAQHGLVARLRSTVA-----GQPDSGTTAGVYIPARLLVR-
Mvan_1536|M.vanbaalenii_PYR-1       MGLFVVGRLAASHGLVVRLRSTVA-----GEPDSGTTAGVYIPARLLIH-
MSMEG_1637|M.smegmatis_MC2_155      MGLFVVGRLADQHGLVVRLRSTIP-----DEPGSGTTAGVYVPAQLLVT-
TH_3044|M.thermoresistible__bu      ----XAGRRCPGRAPTPRVGCRAH-----TCPHCGSRA---PPAQ-----
MLBr_00175|M.leprae_Br4923          LGLAIVKQVVINHGGLLRVEDTAP-----GVQPPGTSIYVLLPG------
MAB_1077|M.abscessus_ATCC_1997      LGLAIVKQVVLKHGGAIKVEETDPGAVIDGEPAPGTSMHVLLPG------
                                         . :    :.    :               *:      *       

MUL_2850|M.ulcerans_Agy99           QRPGSAAGQPPQRSAFV---VRPPSSEPAPAPDAAGSAPTGDSTAVPP--
MMAR_1165|M.marinum_M               QRPGPAAGQPPQRRAVV---VRPPSSEPAPAPDAAGSAPTGDSTAVPP--
Mb3400c|M.bovis_AF2122/97           ----TAPAQPPKPRVFA---IKPPCPEPAAA------DPTDVPAAIGP--
Rv3365c|M.tuberculosis_H37Rv        ----TAPAQPPKPRVFA---IKPPCPEPAAA------DPTDVPAAIGP--
MAV_4331|M.avium_104                -RVVAEPSGPRHIRAVSSPSAKLASAIAAPAEEGGRHDGTQQPAARGTRN
Mflv_4889|M.gilvum_PYR-GCK          ---RA----APPVQARD---VRPAAPAPAP-------TPAPAPAP-PPPP
Mvan_1536|M.vanbaalenii_PYR-1       ---TA----PAQYGGRD---DEPVPADAHAGIATALALEVPAGVPREAPA
MSMEG_1637|M.smegmatis_MC2_155      ---EAGTAGTPAFDQFD---AQPEDAATAPGHPTGYPNVVSLDTRFVTTG
TH_3044|M.thermoresistible__bu      ---------PPGSEQQG---GEPPVEHLTVG-------------------
MLBr_00175|M.leprae_Br4923          ---------------------RPMPVSAYS--------------------
MAB_1077|M.abscessus_ATCC_1997      ---------------------RPGPIVR----------------------
                                                         .                            

MUL_2850|M.ulcerans_Agy99           -----LPPVSLLPRRNPGSSGIADVPG--QQPEQQQPPRRRRELKTPWWE
MMAR_1165|M.marinum_M               -----LPPVSLLPRRNPGSSGIADVPG--QQPEQQQPPRRRRELKTPWWE
Mb3400c|M.bovis_AF2122/97           -----LPPVTLLPRRTPGSSGIADVP---AQPMQQ----RRRELKTPWWE
Rv3365c|M.tuberculosis_H37Rv        -----LPPVTLLPRRTPGSSGIADVP---AQPMQQ----RRRELKTPWWE
MAV_4331|M.avium_104                TGDASTPPVTLLPRRNPGSSGIADVAAVPAPPAEPQPRRQRRELATPWWE
Mflv_4889|M.gilvum_PYR-GCK          APVVP--PADVLPQRRP---------------EPPPPVEPP---------
Mvan_1536|M.vanbaalenii_PYR-1       AAAGP--ATDLLPQRRPGASGIVETP----AETPVAPIETPVATSVAVVT
MSMEG_1637|M.smegmatis_MC2_155      SEHDDDLAAGLLPQRNPGASGISEMPGVFAEPEPAAEVSGDAQGEWPQQW
TH_3044|M.thermoresistible__bu      ------IADGVHQRAQP---------------QHPAPVTGER--------
MLBr_00175|M.leprae_Br4923          --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MUL_2850|M.ulcerans_Agy99           TA----------QPAGRPEQAAPQ----QSDTAAFFARRSPAAGAGPDEP
MMAR_1165|M.marinum_M               TA----------QPAGQPEQAAPQ----QSDTAAFFARRSPAAGAGPDEP
Mb3400c|M.bovis_AF2122/97           DR----------FQQEPKQPPAP-------------------------EP
Rv3365c|M.tuberculosis_H37Rv        DR----------FQQEPKQPPAP-------------------------EP
MAV_4331|M.avium_104                ASPAPRPAPEPQQPAPEPQQPAPRPARAASDTSAFFAARPRTETPPETPP
Mflv_4889|M.gilvum_PYR-GCK          -------------PPVETPP------------------------PVETP-
Mvan_1536|M.vanbaalenii_PYR-1       PAATPVAAVTPVAPPVETPPARSEVAAFFSPRPQ----------PTETNG
MSMEG_1637|M.smegmatis_MC2_155      PAPQEAAAPEEVAPQANGRPTDTSSFFASRAQAAGGTQNGAQVNGVHLDG
TH_3044|M.thermoresistible__bu      --------------------------------------------------
MLBr_00175|M.leprae_Br4923          --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MUL_2850|M.ulcerans_Agy99           APSVKPGP-----------------PSVPADPVRDDSIYQKMLSEMTSDP
MMAR_1165|M.marinum_M               APSVKPGP-----------------PSALADPARDDSIYQKMLSEMTSDP
Mb3400c|M.bovis_AF2122/97           RPAPPPAK-----------------PAPPAGPVDDDVIYRRMLSEMVGDP
Rv3365c|M.tuberculosis_H37Rv        RPAPPPAK-----------------PAPPAGPVDDDVIYRRMLSEMVGDP
MAV_4331|M.avium_104                EAPPKPAPKPK--------PEASIPPAASTGPADDDVIYRRMLSEMLGDP
Mflv_4889|M.gilvum_PYR-GCK          --RPGHAD-----------------------IDHDDTIYQKMLSEWLVDP
Mvan_1536|M.vanbaalenii_PYR-1       HARHAAAD-----------------------SDPDDAIYQKMLSEWLVDP
MSMEG_1637|M.smegmatis_MC2_155      AHTNGAANGTADSFTGFFGSSDDQLDQREPAGDPGDSIYQSMVSEFAIDP
TH_3044|M.thermoresistible__bu      --------------------------------------FGGLDVQFAVEG
MLBr_00175|M.leprae_Br4923          -----------------------------------TLADQDMGEANFQDK
MAB_1077|M.abscessus_ATCC_1997      ---------------------------------------PNMGDTAGRRN
                                                                             :        

MUL_2850|M.ulcerans_Agy99           HELANSADLDWRSVWDRGWSAAAEAQETPVQSR-TDHGLPVRTPGARLVP
MMAR_1165|M.marinum_M               HELANSADLDWRSVWDRGWSAAAEAQDTPVQSR-TDHGLPVRTPGARLVP
Mb3400c|M.bovis_AF2122/97           HELAHSPDLDWKSVWDHGWSAAAEAADKPVQSR-TDYGLPVREPGARLVP
Rv3365c|M.tuberculosis_H37Rv        HELAHSPDLDWKSVWDHGWSAAAEAADKPVQSR-TDYGLPVREPGARLVP
MAV_4331|M.avium_104                HDLVNSPDLDWQSVWDRGWTLAAAAEDKPVESHTTDHGLPVRTPGARLVP
Mflv_4889|M.gilvum_PYR-GCK          HELSHSSDLNWKSVWDNGWSAAEAADAAPVRHR-TPEGLPVRRPGARLIP
Mvan_1536|M.vanbaalenii_PYR-1       HELSHSTDLNWKSVWDHGWSAAEAAEAAPVLDH-TAEGLPVRRPGARLVP
MSMEG_1637|M.smegmatis_MC2_155      TTHARSADLDWQTVWEKGWSVAAAAQDAPVDRH-TEEGLPMRTPGARLVP
TH_3044|M.thermoresistible__bu      VALVHR----------AGVVAGLPAEHGDQVGQ-QAGGLRQRQPDG----
MLBr_00175|M.leprae_Br4923          IGPAVQVSGKSANFRDSAHVISVDYQSARAR-------------------
MAB_1077|M.abscessus_ATCC_1997      SGP-------------NAREISVDSQSVPAAWRPS---------------
                                                     .   .                            

MUL_2850|M.ulcerans_Agy99           GAADSDEPTQDEADRPPASD--------------------RGLPPDQPAQ
MMAR_1165|M.marinum_M               GAADSDEPNQDEADRPPASD--------------------RGLPPDQPAQ
Mb3400c|M.bovis_AF2122/97           GAAVPEGPDREHPGAALASN--------------------GGLHPGRAPR
Rv3365c|M.tuberculosis_H37Rv        GAAVPEGPDREHPGAALASN--------------------GGLHPGRAPR
MAV_4331|M.avium_104                GGAHG---AAAEPDDEPGLN--------------------GRSPAPRRPQ
Mflv_4889|M.gilvum_PYR-GCK          G------------------------------------------HADTENG
Mvan_1536|M.vanbaalenii_PYR-1       G------------------------------------------HANGEP-
MSMEG_1637|M.smegmatis_MC2_155      GGVAAAAGRTNGANGHHHSDLNGGVNGEIHGNDNGAEAVASANEADNGMF
TH_3044|M.thermoresistible__bu      --------------------------------------------------
MLBr_00175|M.leprae_Br4923          --------------------------------------------------
MAB_1077|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MUL_2850|M.ulcerans_Agy99           HTAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
MMAR_1165|M.marinum_M               HTAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
Mb3400c|M.bovis_AF2122/97           HAAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
Rv3365c|M.tuberculosis_H37Rv        HAAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
MAV_4331|M.avium_104                HAAVARDPEAVRASFSSHFGGVRTGRSHARESSEGPDQQ
Mflv_4889|M.gilvum_PYR-GCK          HPLPVRDPDAVRASLGGHFGGVHAGRRHAREAAGDDR--
Mvan_1536|M.vanbaalenii_PYR-1       VASAGRDPEAVRNSIGSHFGGVHAGRLRAQETGGADFP-
MSMEG_1637|M.smegmatis_MC2_155      AAFKPRDPEAVRASISSHFGGVHAGRSHARETRGTDNE-
TH_3044|M.thermoresistible__bu      -------VPAVDQPLP-------AGT-------------
MLBr_00175|M.leprae_Br4923          ---------------------------------------
MAB_1077|M.abscessus_ATCC_1997      ---------------------------------------