For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TMFSRPAEPAAAEAPGPAPLGGGAVPAKRPPAWSLSNWPVRWKVLAIVLVPLMLATVFGVLRIHGAMANA AGLRLAAARADVVPAITKYMSALDVALLAGSAGRDAEGAKKNYEARKNELQTRLGDTDVTDDVRAGVNNL LDTGQMLVNKVAEGSLGLRERVTFYAPILLTAENVINASVRVDDERIRAQAQGLSRAVGARGQMTMQKIL VTRGAELPEPQLRTSMATLAGTEPSTLFGMSEVLGAGSPEAKTLQQQMVSRMAIMSDPASVLVDNPDLLR SIQTTDDIADQVIKNTTASVTKSVHAQAAERRNSAILDTALVLAAIVIALAVVLLVARALVRPLRTLRDG ALKVAHTDLEEEIAHVKAGGAEPIPAPLPVYTTEEIGQVAHAVDELHTQALLLAGDEARLRLLVNDMFET MSRRSRSLVDQQLALIDRLERNEDNPERLDNLFRLDHLAARLRRNSANLLVLAGAKLARDQRDPVPLATV INAAVSEVEDYRRVEIAGLPECSLLGAAAGGAIHLFAELIDNALRYSPPTTSARVSASRGGDGGVVVRIA DSGLGMNDADRRIANMRLQAGGDANPDPHPENARHLGLFVVGRIAAWHGMRVGLRGPAANESGSGTTAEV YLPPTVLAGRVVAEPSGPRHIRAVSSPSAKLASAIAAPAEEGGRHDGTQQPAARGTRNTGDASTPPVTLL PRRNPGSSGIADVAAVPAPPAEPQPRRQRRELATPWWEASPAPRPAPEPQQPAPEPQQPAPRPARAASDT SAFFAARPRTETPPETPPEAPPKPAPKPKPEASIPPAASTGPADDDVIYRRMLSEMLGDPHDLVNSPDLD WQSVWDRGWTLAAAAEDKPVESHTTDHGLPVRTPGARLVPGGAHGAAAEPDDEPGLNGRSPAPRRPQHAA VARDPEAVRASFSSHFGGVRTGRSHARESSEGPDQQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4331 | - | - | 100% (947) | hypothetical protein MAV_4331 |
| M. avium 104 | MAV_1095 | - | 5e-10 | 23.06% (412) | sensor histidine kinase |
| M. avium 104 | MAV_3693 | infB | 3e-09 | 28.66% (164) | translation initiation factor IF-2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3400c | - | 0.0 | 64.64% (956) | hypothetical protein Mb3400c |
| M. gilvum PYR-GCK | Mflv_4889 | - | 0.0 | 46.95% (918) | integral membrane sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv3365c | - | 0.0 | 64.64% (956) | hypothetical protein Rv3365c |
| M. leprae Br4923 | MLBr_00175 | - | 1e-08 | 23.58% (335) | putative two-component system sensor kinase |
| M. abscessus ATCC 19977 | MAB_0869c | - | 7e-11 | 28.52% (263) | resuscitation-promoting factor RpfA |
| M. marinum M | MMAR_1165 | - | 0.0 | 64.78% (954) | putative regultory protein |
| M. smegmatis MC2 155 | MSMEG_1637 | - | 0.0 | 49.10% (945) | periplasmic sensor signal transduction histidine kinase |
| M. thermoresistible (build 8) | TH_3044 | - | 1e-175 | 54.34% (587) | PUTATIVE integral membrane sensor signal transduction histidine |
| M. ulcerans Agy99 | MUL_2850 | - | 0.0 | 64.05% (954) | putative regultory protein |
| M. vanbaalenii PYR-1 | Mvan_1536 | - | 0.0 | 50.38% (913) | integral membrane sensor signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3400c|M.bovis_AF2122/97 MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTI
Rv3365c|M.tuberculosis_H37Rv MTMFARPTIPVAAAASDISAPAQPARGKPQQRPPSWSPRNWPVRWKVFTI
MMAR_1165|M.marinum_M MTMFARPTTPVEAAPG--APVASGAESAPPKRPPAWSLGNWPVGWKVVAI
MUL_2850|M.ulcerans_Agy99 MTMFARLTTPVEAAPG--APVASGAESAPPKRPPAWSLGNWPVGWKVVAI
MAV_4331|M.avium_104 MTMFSRPAEPAAAEAP--GPAPLGGGAVPAKRPPAWSLSNWPVRWKVLAI
MSMEG_1637|M.smegmatis_MC2_155 ------------------------------------------MSRKVLAI
TH_3044|M.thermoresistible__bu MTVFSQLRKSDGTNRD-----VEPPAPDPIKKPSRWALTNWPVRWKVFAI
Mflv_4889|M.gilvum_PYR-GCK ----------------------MARSLRPDQRPSRWAPPNWPVRVKVLAL
Mvan_1536|M.vanbaalenii_PYR-1 -----------------------MNDTRSVKRPAPLALSNWPVRVKVLAI
MLBr_00175|M.leprae_Br4923 -----------------------MVRFAWRRRASLRATSSLSLRWRVMLL
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 ALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAV
Rv3365c|M.tuberculosis_H37Rv ALLPLVVAMVLAGLRVEAAMASTSGLRLVAARAEMIPAITKYMSALDVAV
MMAR_1165|M.marinum_M AVVPLLLAMVLGGLRIHGGMANSSGLRLADARADVIPAITKYMSALDVAL
MUL_2850|M.ulcerans_Agy99 AVVPLLLAMVLGGLRIHGGMANSSGLRLADARADVIPAITKYMSALDVAL
MAV_4331|M.avium_104 VLVPLMLATVFGVLRIHGAMANAAGLRLAAARADVVPAITKYMSALDVAL
MSMEG_1637|M.smegmatis_MC2_155 VLVPLILAATFGGLRIYASVTEAADLRLAADRAELIPDINNYMAALEGVL
TH_3044|M.thermoresistible__bu VLVPLLLIATFAGLRVYSGVAENAELRRAVDRAEVIPPVVDYMAALEEAM
Mflv_4889|M.gilvum_PYR-GCK VTVPLVLACVFGGLRISASTVEARELAHAADRAQMVPAVVDYMAALQNAM
Mvan_1536|M.vanbaalenii_PYR-1 VVVPLLLACVFGGLRIYSSATEAAELRHAAQRADMVPAVVDYMAALEAAM
MLBr_00175|M.leprae_Br4923 AMSMVAMVVVLMAFAVYVVIS-----------AALYSDIDNQLQSRAQLL
MAB_0869c|M.abscessus_ATCC_199 -------------------------MSGRHSKPSKASAKAAKVAVAGAGL
. . : :
Mb3400c|M.bovis_AF2122/97 LASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQAL
Rv3365c|M.tuberculosis_H37Rv LASSTGHDVEGAQKNFTARKYELQTRLADTDVIADVRSGVNTLLNGGQAL
MMAR_1165|M.marinum_M LASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSVLNGGQAL
MUL_2850|M.ulcerans_Agy99 LASSTGRDVEGPKKNFAARKNELQTRLANTNVLSDVRSGVNSVLNGGQAL
MAV_4331|M.avium_104 LAGSAGRDAEGAKKNYEARKNELQTRLGDTDVTDDVRAGVNNLLDTGQML
MSMEG_1637|M.smegmatis_MC2_155 VASSGAGDGQAALATFDSRKSELQQRVDSTDVLGDVREAVGTMLDKGQTL
TH_3044|M.thermoresistible__bu VAATTGRETQPALARFDERKTELRERAEQGEIVPDVRAAVDTLLDGGQDL
Mflv_4889|M.gilvum_PYR-GCK VTAGGGGNPAAALGEFDFRKAELSRVLEGADVDDSVRLATNTLLEYGQNL
Mvan_1536|M.vanbaalenii_PYR-1 VTATEGGDARQALTVFESRRTGLQHLLDVTPVDDGVRLATNTLIDFGQNL
MLBr_00175|M.leprae_Br4923 IASG----------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 VGGG----------------------------------------------
: .
Mb3400c|M.bovis_AF2122/97 LDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRA
Rv3365c|M.tuberculosis_H37Rv LDKVLADSIGLRDRVTAYAPLLLTAQNVIDASVRVDSEQIRTQVQGLSRA
MMAR_1165|M.marinum_M LDQTLANTISLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRA
MUL_2850|M.ulcerans_Agy99 LDQTLANTSSLRDRVTAYVPLLLTAEDAINASVRVDNEQIRAEVQGLSRA
MAV_4331|M.avium_104 VNKVAEGSLGLRERVTFYAPILLTAENVINASVRVDDERIRAQAQGLSRA
MSMEG_1637|M.smegmatis_MC2_155 VDASMANTVGLRQRILDYAPLLLTAEAAVTGSTHSADQRVQTEAEALGRA
TH_3044|M.thermoresistible__bu INKVMSNVVDLRQRVTAYAPLLLTAETAITGSARDDAPGVQRKAEALSRA
Mflv_4889|M.gilvum_PYR-GCK LDRIGAAEMNLRTQVMTFGPLLITAQTALTGSVGSDEDSVRTEADVLSRA
Mvan_1536|M.vanbaalenii_PYR-1 IDKISADAIDLRTRVMTYAPLLITSETAITGLVGADDERVRSDADTLSRA
MLBr_00175|M.leprae_Br4923 -------------------SLAADPGKAIEGTAYSDVN------------
MAB_0869c|M.abscessus_ATCC_199 ---------------------LMMAATANAATDGEWDQVARCESGG----
. . .
Mb3400c|M.bovis_AF2122/97 VGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAG
Rv3365c|M.tuberculosis_H37Rv VGARGQMTMQEILVTRGADLAEPQLRSAMVTLAGTEPSTLFGMSAALGAG
MMAR_1165|M.marinum_M VGARGQMTLQEILVTRGAEAPEAQLRNSMITLAGTEPSTLFGMTEVLGVG
MUL_2850|M.ulcerans_Agy99 VGARGQMTLQEILVTRGVEAPEAQLRNSMITLAGTGPSTLFGMTEVLGVG
MAV_4331|M.avium_104 VGARGQMTMQKILVTRGAELPEPQLRTSMATLAGTEPSTLFGMSEVLGAG
MSMEG_1637|M.smegmatis_MC2_155 IGARGQMTIQEMMVNRGAEEPEPVLRKSMITMAGTEPSTVAALTKVLGSA
TH_3044|M.thermoresistible__bu VGARGQMTMQEMSVTSGGYLPEPELRTSLITLAGTEPSTINGMIAYLGND
Mflv_4889|M.gilvum_PYR-GCK VGARGQMAMQDMLVTRGGELPEPLLRSAMVTLAGTEPATVTAMGTFLGGA
Mvan_1536|M.vanbaalenii_PYR-1 VGARGQMAMQRMLVNSGAELPEPLLRSAMVTIAGTEPATVTAMGGYLGGA
MLBr_00175|M.leprae_Br4923 ---------------------------AMLVNPGHSIYTANQPGQTLPVG
MAB_0869c|M.abscessus_ATCC_199 -------------------------NWAINTGNGYQGGLQFSPSTWINSG
:: . * :
Mb3400c|M.bovis_AF2122/97 SPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTT
Rv3365c|M.tuberculosis_H37Rv SPDTKNLQQQMVTRMAIMSDPAVALVNNPELLHSIQITRDIAEQVITDTT
MMAR_1165|M.marinum_M SPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQSIQITRGIAEQVINDAT
MUL_2850|M.ulcerans_Agy99 SPDAKTLHQQMVTRMAIISDPDSVLAGNPQLLQSIQITRGIAEQVINDAT
MAV_4331|M.avium_104 SPEAKTLQQQMVSRMAIMSDPASVLVDNPDLLRSIQTTDDIADQVIKNTT
MSMEG_1637|M.smegmatis_MC2_155 SDDATTLRDEMVKRMAIMANPGIPLVGNPVLLESLENTRKIAEQIITDNT
TH_3044|M.thermoresistible__bu SQQAATLRTEMVRRMSMMSDPAVPLAANPELLGSQQVTRSVADAMIAELA
Mflv_4889|M.gilvum_PYR-GCK SDRADALRSQMVRRMSLLSDPAVVLVGNPELLMSQKITADIAQSLINRIA
Mvan_1536|M.vanbaalenii_PYR-1 TEQASTLRSEMVKRMALLSEPTTALVGNPELLASQKITGDIAAGLIAQTT
MLBr_00175|M.leprae_Br4923 TAEKAVIRGELFMSQRTASDQRILAIHLP-----------------NDSS
MAB_0869c|M.abscessus_ATCC_199 GGQYAPSAHLATKEQQIAVAEKVLAGQGRGAWPVCGRGLSGSTPRTAPAA
:
Mb3400c|M.bovis_AF2122/97 EAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVL
Rv3365c|M.tuberculosis_H37Rv EAVTKSVQSQATDRRDAAIRDAVLVLAAIATAIVVVLVVARTLVGPMRVL
MMAR_1165|M.marinum_M ESVTKAVQARASARRDAAIRDTVFVLGAILVAVVVVLLVARALVRPLRQL
MUL_2850|M.ulcerans_Agy99 ESVTKAVQARASARRDAAIRDTVLVLGAILVAVVVVLLVARALVRPLRQL
MAV_4331|M.avium_104 ASVTKSVHAQAAERRNSAILDTALVLAAIVIALAVVLLVARALVRPLRTL
MSMEG_1637|M.smegmatis_MC2_155 SAIPAAVEAEAADARNDAIRDSVLVALAVISALVVVLLVARSLVRPLRTL
TH_3044|M.thermoresistible__bu TTIPDEVRQAADDQRTAAIRDTVLVLLAIAVAAVVVLLVARSLVRPLRTL
Mflv_4889|M.gilvum_PYR-GCK DEIPARVSRQADDARTAAIRDSVLVGAAILVALILVLWVARSLVRPLRTL
Mvan_1536|M.vanbaalenii_PYR-1 EDIPAAVARQADDARTAAIRDAALVGAAILVALILVTLVARSMVRPLRTL
MLBr_00175|M.leprae_Br4923 LLISKSLRPTEAVMTKLRWVLLIVGSLGVAVAAVAGGMVTRAGLRPVGRL
MAB_0869c|M.abscessus_ATCC_199 NITPAAHHEEQAAAEPAPAPEPPAEGDEQFVAEAPEAPAIDEAPAPEEAP
. * . *
Mb3400c|M.bovis_AF2122/97 RDGALKVAHTDLDGEIAAVRAG-DEPIPEPLAVYTTEEIGQVAHAVDELH
Rv3365c|M.tuberculosis_H37Rv RDGALKVAHTDLDGEIAAVRAG-DEPIPEPLAVYTTEEIGQVAHAVDELH
MMAR_1165|M.marinum_M RDGALKVAHTDLEGEIAKVRAG-AEPIPEPLPVYTTEEIGQVAHAVDELH
MUL_2850|M.ulcerans_Agy99 RDGALKVAHTDLEGEIAKVREG-AEPIPEPLPVYTTEEIGQVAHAVDELH
MAV_4331|M.avium_104 RDGALKVAHTDLEEEIAHVKAGGAEPIPAPLPVYTTEEIGQVAHAVDELH
MSMEG_1637|M.smegmatis_MC2_155 RDGALKVAHEDLAKEIERVRAGGEPGPITPLPVYTSEEVGQVAHAVDELH
TH_3044|M.thermoresistible__bu RDSALKVAHGDLARELDQVRETGELPEVEPIAVHTTEEIGQVAHAVDELH
Mflv_4889|M.gilvum_PYR-GCK RDSALRVAHDDLGREVERVRDDGKEFAVDPIPVHTTEEVGQVAHAVDELH
Mvan_1536|M.vanbaalenii_PYR-1 RDSALKVAHEDLPREVEHVRSDGKEFPVQPIPVHTTEEVGQVAHAVDELH
MLBr_00175|M.leprae_Br4923 TEAAERVARTD---------------DLRPIPVFGSDELARLTEAFNLML
MAB_0869c|M.abscessus_ATCC_199 APEAQDVDFQS------------GPAPEEPAPAPEPAPVDEAQAPAPELI
* * . * .. . : . . :
Mb3400c|M.bovis_AF2122/97 TRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPA
Rv3365c|M.tuberculosis_H37Rv TRALLLAGEETRLRLLVNEMFETMSRRSRSLVDQQLSVIDQLERNEEDPA
MMAR_1165|M.marinum_M AQVLVLAGDEARLRSLVNDMFETMSRRSRSLVDQQLSLIDGLERNEEDPE
MUL_2850|M.ulcerans_Agy99 AQVLVLAGDEARLRSLVNDMFETMSRRSRSLVDQQLSLIDGLERNEEDPD
MAV_4331|M.avium_104 TQALLLAGDEARLRLLVNDMFETMSRRSRSLVDQQLALIDRLERNEDNPE
MSMEG_1637|M.smegmatis_MC2_155 EQAVFLAGEQAQLQLQVADMFETLSRRSRSLVDQQLSLIDELERNEDDPQ
TH_3044|M.thermoresistible__bu EQAVFLAGEQTRLQMQISDMFETLSRRSRSLVDQQLALIDQLERNEEDPQ
Mflv_4889|M.gilvum_PYR-GCK QQALVLAGAQARLQLQVTDMFETLSRRNRSLVEQQLSLIDGLERDEEDPD
Mvan_1536|M.vanbaalenii_PYR-1 QQAVMLAGEQARLQLQVTDMFETLSRRNRSLVDQQLSLIDRLERDEEDPD
MLBr_00175|M.leprae_Br4923 RALAESRERQARLVTDAGHELRTPLTSLRTNVELLIASMAPEAPRLPDQE
MAB_0869c|M.abscessus_ATCC_199 AAPAP-----------------------------EAPVVDEAPAPEEAPA
. :
Mb3400c|M.bovis_AF2122/97 RLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSE
Rv3365c|M.tuberculosis_H37Rv RLDSLFRLDHLAARLRRNSANLLVLAGAQITRDHREPVPLSTVISAAVSE
MMAR_1165|M.marinum_M RLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVISAAVSE
MUL_2850|M.ulcerans_Agy99 RLDTLFRLDHLAARLRRNSANLLVLAGAQISRDHREPVPLLTVISAAVSE
MAV_4331|M.avium_104 RLDNLFRLDHLAARLRRNSANLLVLAGAKLARDQRDPVPLATVINAAVSE
MSMEG_1637|M.smegmatis_MC2_155 RLNSLFRLDHLAARMRRNGANLLVLSGAKVTREKSEPVAVATVINAAASE
TH_3044|M.thermoresistible__bu RLQNLFRLDHLAARMRRNGANLLVLAGAKVPREQAAPMPVASLIHAAASE
Mflv_4889|M.gilvum_PYR-GCK RLQSLFQLDHLAARMRRNGANLLVLAGARISHDRAEPVAVAAIVNAAASE
Mvan_1536|M.vanbaalenii_PYR-1 RLESLFRLDHLAARMRRNGSNLMVLAGAQISRERAESVPVTALVNAAASE
MLBr_00175|M.leprae_Br4923 MADLRADVLAQIEELSTLVGDLVDLTRDDAGQVVHEPIDMSEVLYRSLER
MAB_0869c|M.abscessus_ATCC_199 PEAPAADDQVLPYELQSGP-----------APAEPAPAPEPAPAPAAAPE
.: . : .
Mb3400c|M.bovis_AF2122/97 VEDYRRVDIARVPDC--AVVGAAAGGVIHLLAELIDNALRYSSPTTPVRV
Rv3365c|M.tuberculosis_H37Rv VEDYRRVDIARVPDC--AVVGAAAGGVIHLLAELIDNALRYSSPTTPVRV
MMAR_1165|M.marinum_M VEDYRRVETGGVADC--TVIGAAAGAVIHLLAELIDNALNYSPPTAPVRV
MUL_2850|M.ulcerans_Agy99 VEDYRRVETGGVADC--TVIGAAAGAVIHLLAELIDNALNYSPPTAPVRV
MAV_4331|M.avium_104 VEDYRRVEIAGLPEC--SLLGAAAGGAIHLFAELIDNALRYSPPTTSARV
MSMEG_1637|M.smegmatis_MC2_155 VEDYTRVVTSDVADA--DVVGSAAGDLIHLLAELLDNALRYSPPTSQVRV
TH_3044|M.thermoresistible__bu VEDYTRIVMTTVPDS--EVHGSVAGDLVHILAELLDNALRYSPPTAQVRV
Mflv_4889|M.gilvum_PYR-GCK VEEYPRIVTGDLPDS--EVAASAAGDLVHLLAELLDNGLRYSPPHTQVRV
Mvan_1536|M.vanbaalenii_PYR-1 VEDYTRIVTTGLPDG--EVDGVVAGDLVHLLAELLDNALRYSPPTTEVRV
MLBr_00175|M.leprae_Br4923 VRRRRNDIHFDVQAIGWQIYGDAAG-LSRAVLNLMDNAAKWSPSGGRVVV
MAB_0869c|M.abscessus_ATCC_199 IP-----LPAGVPDA--ADIGFAAGKAAFDAGPVASNGIPTSPEAVAGVV
: : . .** : .*. *. *
Mb3400c|M.bovis_AF2122/97 AAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTP----DSARH
Rv3365c|M.tuberculosis_H37Rv AAAIGSEGSVLLRISDSGLGMTDADRRMANMRLRAGGEVTP----DSARH
MMAR_1165|M.marinum_M SAVRGSEGGVLLRIADSGLGMTESDRRMANMRLHAGVEVTP----ANARH
MUL_2850|M.ulcerans_Agy99 SAVRGSEGGVLLRIADSGLGMTESDRRMANMRLHSGGEVTP----ANARH
MAV_4331|M.avium_104 SASRGGDGGVVVRIADSGLGMNDADRRIANMRLQAGGDANPDPHPENARH
MSMEG_1637|M.smegmatis_MC2_155 SAVFAGNGALVIEVADVGLGMTESDLRVANIRLKSGGEVNP----YTARH
TH_3044|M.thermoresistible__bu SAGHADTGALVIEVSDAGLGMSESDLRMANARLESXX-------------
Mflv_4889|M.gilvum_PYR-GCK SAVPTDNNGLVIEVSDTGLGMTEADLRVANMRLESGGEVNP----YTARH
Mvan_1536|M.vanbaalenii_PYR-1 SAVPTGNNGLVIEVSDTGLGMTESDLRVANTRLESGGEVNP----YTARH
MLBr_00175|M.leprae_Br4923 TMRQFDPSHVELVVSDYGPGIPPQERRLVFERFYRSTTARS----LPGSG
MAB_0869c|M.abscessus_ATCC_199 RHLP-DPNNLPPGTTDVAPGDSRGVSYLKDIVFAMQTQDVK---------
. . : :* . * : :
Mb3400c|M.bovis_AF2122/97 MGLFVVGRLAGRHGIRVGLRGPVTGEQGTGTTAEVYLPLAVLEG-----T
Rv3365c|M.tuberculosis_H37Rv MGLFVVGRLAGRHGIRVGLRGPVTGEQGTGTTAEVYLPLAVLEG-----T
MMAR_1165|M.marinum_M MGLFVVGRLAARHGIRVGLRGPSTGEAGGGTTAEVYLPRTVLVDGQRPGP
MUL_2850|M.ulcerans_Agy99 MGLFVVGRLAARHGIRVGLRGPSTGEAGGGTTAEVYLPRTVLVDGQRPGS
MAV_4331|M.avium_104 LGLFVVGRIAAWHGMRVGLRGPAANESGSGTTAEVYLPPTVLAG--RVVA
MSMEG_1637|M.smegmatis_MC2_155 MGLFVVGRLADQHGLVVRLRSTIPDEPGSGTTAGVYVPAQLLVT------
TH_3044|M.thermoresistible__bu ----XAGRRCPGRAPTPRVGCRAHTCPHCGSRAPP---------------
Mflv_4889|M.gilvum_PYR-GCK MGLFVVSRLAAQHGLVARLRSTVAGQPDSGTTAGVYIPARLLVR------
Mvan_1536|M.vanbaalenii_PYR-1 MGLFVVGRLAASHGLVVRLRSTVAGEPDSGTTAGVYIPARLLIH------
MLBr_00175|M.leprae_Br4923 LGLAIVKQVVINHGGLLRVEDTAPGVQPPGTSIYVLLPGRPMPVS-----
MAB_0869c|M.abscessus_ATCC_199 ---------ASDAILALAQR------------------------------
Mb3400c|M.bovis_AF2122/97 APAQPPKPRVFA---IKPPCPEPAAA------DPTDVPAAIGP-------
Rv3365c|M.tuberculosis_H37Rv APAQPPKPRVFA---IKPPCPEPAAA------DPTDVPAAIGP-------
MMAR_1165|M.marinum_M AAGQPPQRRAVV---VRPPSSEPAPAPDAAGSAPTGDSTAVPP-------
MUL_2850|M.ulcerans_Agy99 AAGQPPQRSAFV---VRPPSSEPAPAPDAAGSAPTGDSTAVPP-------
MAV_4331|M.avium_104 EPSGPRHIRAVSSPSAKLASAIAAPAEEGGRHDGTQQPAARGTRNTGDAS
MSMEG_1637|M.smegmatis_MC2_155 -EAGTAGTPAFDQFDAQPEDAATAPGHPTGYPNVVSLDTRFVTTGSEHDD
TH_3044|M.thermoresistible__bu ---------------AQPPGSEQQGGEPP---------VEHLTVG-----
Mflv_4889|M.gilvum_PYR-GCK -RAAPPVQAR----DVRPAAPAPAP-------TPAPAPAP-PPPPAPVV-
Mvan_1536|M.vanbaalenii_PYR-1 -TAPAQYGGR----DDEPVPADAHAGIATALALEVPAGVPREAPAAAAG-
MLBr_00175|M.leprae_Br4923 ---------------AYSTLADQDMG------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 LPPVTLLPRRTPGSSGIADVP---AQPMQQ----RRRELKTPWWEDR---
Rv3365c|M.tuberculosis_H37Rv LPPVTLLPRRTPGSSGIADVP---AQPMQQ----RRRELKTPWWEDR---
MMAR_1165|M.marinum_M LPPVSLLPRRNPGSSGIADVPG--QQPEQQQPPRRRRELKTPWWETA---
MUL_2850|M.ulcerans_Agy99 LPPVSLLPRRNPGSSGIADVPG--QQPEQQQPPRRRRELKTPWWETA---
MAV_4331|M.avium_104 TPPVTLLPRRNPGSSGIADVAAVPAPPAEPQPRRQRRELATPWWEASPAP
MSMEG_1637|M.smegmatis_MC2_155 DLAAGLLPQRNPGASGISEMPGVFAEPEPAAEVSGDAQGEWPQQWPAP--
TH_3044|M.thermoresistible__bu -IADGVHQR---------------AQPQHPAPVTGERFGGLDVQFAV---
Mflv_4889|M.gilvum_PYR-GCK -PPADVLPQRRP---------------EPPPPVEPP--------------
Mvan_1536|M.vanbaalenii_PYR-1 -PATDLLPQRRPGASGIVET----PAETPVAPIETPVATSVAVVTPAA--
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 -------FQQEPKQPPAP-------------------------EPRPAPP
Rv3365c|M.tuberculosis_H37Rv -------FQQEPKQPPAP-------------------------EPRPAPP
MMAR_1165|M.marinum_M -------QPAGQPEQAAPQ----QSDTAAFFARRSPAAGAGPDEPAPSVK
MUL_2850|M.ulcerans_Agy99 -------QPAGRPEQAAPQ----QSDTAAFFARRSPAAGAGPDEPAPSVK
MAV_4331|M.avium_104 RPAPEPQQPAPEPQQPAPRPARAASDTSAFFAARPRTETPPETPPEAPPK
MSMEG_1637|M.smegmatis_MC2_155 -------QEAAAPEEVAPQANGRPTDTSSFFASRAQAAGGTQNGAQVNGV
TH_3044|M.thermoresistible__bu --------EGVALVHRAGVVAGLP------------AEHGDQVGQQAGG-
Mflv_4889|M.gilvum_PYR-GCK -----------------PPVETPP-------------------PVETP--
Mvan_1536|M.vanbaalenii_PYR-1 -------TPVAAVTPVAPPVETPPARSEV-----AAFFSPRPQPTETNG-
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 PAK--------------------------PAPPAGPVDDDVIYRRMLSEM
Rv3365c|M.tuberculosis_H37Rv PAK--------------------------PAPPAGPVDDDVIYRRMLSEM
MMAR_1165|M.marinum_M PGP--------------------------PSALADPARDDSIYQKMLSEM
MUL_2850|M.ulcerans_Agy99 PGP--------------------------PSVPADPVRDDSIYQKMLSEM
MAV_4331|M.avium_104 PAPKPKPEAS-----------------IPPAASTGPADDDVIYRRMLSEM
MSMEG_1637|M.smegmatis_MC2_155 HLDGAHTNGAANGTADSFTGFFGSSDDQLDQREPAGDPGDSIYQSMVSEF
TH_3044|M.thermoresistible__bu ----------------------------LRQRQPDGVP------------
Mflv_4889|M.gilvum_PYR-GCK -----------------------------RPGHADIDHDDTIYQKMLSEW
Mvan_1536|M.vanbaalenii_PYR-1 ---------------------------HARHAAADSDPDDAIYQKMLSEW
MLBr_00175|M.leprae_Br4923 ---------------------------------EANFQDKIGPAVQVSGK
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 VGDPHELAHSPDLDWKSVWDHGWSAAAEAADKPVQSR-TDYGLPVREPGA
Rv3365c|M.tuberculosis_H37Rv VGDPHELAHSPDLDWKSVWDHGWSAAAEAADKPVQSR-TDYGLPVREPGA
MMAR_1165|M.marinum_M TSDPHELANSADLDWRSVWDRGWSAAAEAQDTPVQSR-TDHGLPVRTPGA
MUL_2850|M.ulcerans_Agy99 TSDPHELANSADLDWRSVWDRGWSAAAEAQETPVQSR-TDHGLPVRTPGA
MAV_4331|M.avium_104 LGDPHDLVNSPDLDWQSVWDRGWTLAAAAEDKPVESHTTDHGLPVRTPGA
MSMEG_1637|M.smegmatis_MC2_155 AIDPTTHARSADLDWQTVWEKGWSVAAAAQDAPVDRH-TEEGLPMRTPGA
TH_3044|M.thermoresistible__bu AVDQPLPAGT----------------------------------------
Mflv_4889|M.gilvum_PYR-GCK LVDPHELSHSSDLNWKSVWDNGWSAAEAADAAPVRHR-TPEGLPVRRPGA
Mvan_1536|M.vanbaalenii_PYR-1 LVDPHELSHSTDLNWKSVWDHGWSAAEAAEAAPVLDH-TAEGLPVRRPGA
MLBr_00175|M.leprae_Br4923 SANFRDSAHVISVDYQSARAR-----------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 RLVPGAAVPEGPDREHPGAALASN--------------------GGLHPG
Rv3365c|M.tuberculosis_H37Rv RLVPGAAVPEGPDREHPGAALASN--------------------GGLHPG
MMAR_1165|M.marinum_M RLVPGAADSDEPNQDEADRPPASD--------------------RGLPPD
MUL_2850|M.ulcerans_Agy99 RLVPGAADSDEPTQDEADRPPASD--------------------RGLPPD
MAV_4331|M.avium_104 RLVPGGAHG---AAAEPDDEPGLN--------------------GRSPAP
MSMEG_1637|M.smegmatis_MC2_155 RLVPGGVAAAAGRTNGANGHHHSDLNGGVNGEIHGNDNGAEAVASANEAD
TH_3044|M.thermoresistible__bu --------------------------------------------------
Mflv_4889|M.gilvum_PYR-GCK RLIPG------------------------------------------HAD
Mvan_1536|M.vanbaalenii_PYR-1 RLVPG------------------------------------------HAN
MLBr_00175|M.leprae_Br4923 --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3400c|M.bovis_AF2122/97 RAPRHAAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
Rv3365c|M.tuberculosis_H37Rv RAPRHAAAVRDPDAVRASISSHFGGVRTGRSHARESSQGPNQQ
MMAR_1165|M.marinum_M QPAQHTAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
MUL_2850|M.ulcerans_Agy99 QPAQHTAAMRDPNAVRASMSSHFGGVHTGRAHAHRASQEPDQQ
MAV_4331|M.avium_104 RRPQHAAVARDPEAVRASFSSHFGGVRTGRSHARESSEGPDQQ
MSMEG_1637|M.smegmatis_MC2_155 NGMFAAFKPRDPEAVRASISSHFGGVHAGRSHARETRGTDNE-
TH_3044|M.thermoresistible__bu -------------------------------------------
Mflv_4889|M.gilvum_PYR-GCK TENGHPLPVRDPDAVRASLGGHFGGVHAGRRHAREAAGDDR--
Mvan_1536|M.vanbaalenii_PYR-1 GEP-VASAGRDPEAVRNSIGSHFGGVHAGRLRAQETGGADFP-
MLBr_00175|M.leprae_Br4923 -------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------