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MSRKDGARRAVRIAIIDDHDVVHAGIRAWCEEADPPIELVGSFLRPSEYFSKYPTATDQVDVVLFDVQIE GNRPDFDTLSKLAERDQPVVVYSHITTDEVILTSLDLGAITYLVKSEGRRHLIEAIHAAHTDTPYVGPRM GNAMLNDSTVGRIKLTDREKQVLVAWFQTESKDLVAKRLFIAPSTVRTHLQRARAKYAGVGRPAPTKSAL LARAIEDGILSLNDLY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1515 | - | - | 100% (226) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5967 | - | 9e-15 | 50.77% (65) | response regulator receiver protein |
| M. vanbaalenii PYR-1 | Mvan_1358 | - | 8e-14 | 28.30% (212) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 8e-12 | 26.51% (215) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_4904 | - | 1e-106 | 82.74% (226) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 8e-12 | 26.51% (215) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1522 | - | 9e-10 | 25.13% (195) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_3480 | - | 2e-11 | 27.19% (217) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_4109 | - | 9e-10 | 26.39% (216) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_1197 | - | 8e-24 | 62.65% (83) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_2159 | - | 1e-10 | 25.23% (218) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_2423 | devR | 2e-11 | 26.61% (218) | two component transcriptional regulatory protein DevR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3157c|M.bovis_AF2122/97 ---------MVKVFLVDDHEVVRRGLVDLLGA-DPELDVVGEAGSVAEAM
Rv3133c|M.tuberculosis_H37Rv ---------MVKVFLVDDHEVVRRGLVDLLGA-DPELDVVGEAGSVAEAM
MUL_2423|M.ulcerans_Agy99 ---------MVTVFLVDDHEVVRRGLIDLLDA-DPQLDVVGEAGSVSEAM
TH_2159|M.thermoresistible__bu ---------MVSVFLVDDHEVVRRGLIDLLDS-DPDLEVVGEAGTVAQAM
MMAR_3480|M.marinum_M ---------MVKVFLVDDHEVVRRGLVDLLGS-DPDLEIIGEAGSVSEAM
MAV_4109|M.avium_104 ---------MVKVFLVDDHEVVRRGLCDLLSS-DPDLRIVGEAGTVAEAK
MAB_1522|M.abscessus_ATCC_1997 -----MTDTEVGVLLVDDQELVRTGLRRILRR-KDGFAIVGECADGSEVA
Mvan_1515|M.vanbaalenii_PYR-1 MSRKDGARRAVRIAIIDDHDVVHAGIRAWCEEADPPIELVGSFLRPSEYF
Mflv_4904|M.gilvum_PYR-GCK MSREDDTRRPVRIAIIDDHDVVHAGIQAWCAEADPPIDLADSFQRPDEYF
MSMEG_1197|M.smegmatis_MC2_155 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 ARVPAARPDVAVLDVRLP-DGNGIELCRDLLSRMPDLRCLILTSYTSDEA
Rv3133c|M.tuberculosis_H37Rv ARVPAARPDVAVLDVRLP-DGNGIELCRDLLSRMPDLRCLILTSYTSDEA
MUL_2423|M.ulcerans_Agy99 ARIPAANPDVAVLDVRLP-DGDGIELCRDLLSRMPNLRCLILTSYTSDEA
TH_2159|M.thermoresistible__bu ARIPAAQPDVAVLDVRLP-DGNGVELCRDLLARMPDLRCLMLTSYTSDQA
MMAR_3480|M.marinum_M ARIPALQPDVAVLDVRLP-DGNGIELCRDLLSDLPELRCLMLTSFTSDEA
MAV_4109|M.avium_104 ARIPAARPDVAVLDVRLP-DGNGIELCRDLLSEHPDLRCLMLTSFTSDEA
MAB_1522|M.abscessus_ATCC_1997 AAVSRARPDVVIMDLRMK-QMSGIEAIR-LLHAAQGPPALALTTFDDDEL
Mvan_1515|M.vanbaalenii_PYR-1 SKYPTATDQVDVVLFDVQIEGNRPDFDTLSKLAERDQPVVVYSHITTDEV
Mflv_4904|M.gilvum_PYR-GCK AKYPDAADDVDVVLLDLQIEGNRPDFDALSKLAASGRRVIVYSHITADEV
MSMEG_1197|M.smegmatis_MC2_155 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 MLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLR-
Rv3133c|M.tuberculosis_H37Rv MLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLR-
MUL_2423|M.ulcerans_Agy99 MLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALMSRLR-
TH_2159|M.thermoresistible__bu MLDAILAGASGYVVKDIKGMELAQAIKDVGAGRSLLDNRAAEALMAKLR-
MMAR_3480|M.marinum_M MLEAILAGASGYVVKDIKGMELARAIKDVGAGKSLLDNRAAAALMAKLR-
MAV_4109|M.avium_104 MLEAILAGASGFVIKDIKGMELARAIKDVGAGKSLLDNRAAAALMAKLR-
MAB_1522|M.abscessus_ATCC_1997 LSGALRAGAAGFILKDSPAEELVRAVHAVARGEAYLDPAVTSRVLNAYRR
Mvan_1515|M.vanbaalenii_PYR-1 ILTSLDLGAITYLVKSEGRRHLIEAIHAAHTDTPYVGPRMGNAMLNDST-
Mflv_4904|M.gilvum_PYR-GCK ILTCLELGAVTYLVKSEGKRHLIEAVHSAHTSTPYVGPRMGKAMLNDST-
MSMEG_1197|M.smegmatis_MC2_155 ----------------------------------------MTAMPVDRP-
:
Mb3157c|M.bovis_AF2122/97 -GAAEKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSR
Rv3133c|M.tuberculosis_H37Rv -GAAEKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSR
MUL_2423|M.ulcerans_Agy99 -GVVERPDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSR
TH_2159|M.thermoresistible__bu -GADHQPDPLAGLSDQERVLLSLIGEGLTNKQIAARMFLAEKTVKNYVSR
MMAR_3480|M.marinum_M -GGAEQKDPLSGLTEQERTLLGHLSEGLTNRQIAARMFLAEKTVKNYVSR
MAV_4109|M.avium_104 -GSAAQADPLSGLTEQERTLLGLLSEGLTNRQIAARMFLAEKTVKNYVSR
MAB_1522|M.abscessus_ATCC_1997 APAAVSGDAQDKLTARELDVLALIASGATNSEIAEQLVISEVTVKSHIGR
Mvan_1515|M.vanbaalenii_PYR-1 -------VGRIKLTDREKQVLVAWFQTESKDLVAKRLFIAPSTVRTHLQR
Mflv_4904|M.gilvum_PYR-GCK -------MGRIKLTDREKQVLIAWFQTESKDLVAERLFIAPTTVRTHLQR
MSMEG_1197|M.smegmatis_MC2_155 -------LPRPELAPREKEVLLAWIRTDSKDGVARQLHIAPTTVRTHLQR
*: :* :* :: :* :: :: **:.:: *
Mb3157c|M.bovis_AF2122/97 LLAKLGMERRTQAAVFATELKR--SRPPGDGP---
Rv3133c|M.tuberculosis_H37Rv LLAKLGMERRTQAAVFATELKR--SRPPGDGP---
MUL_2423|M.ulcerans_Agy99 LLAKLGMERRTQAAVFAAELKR--ARSAGHR----
TH_2159|M.thermoresistible__bu LLAKLGMERRTQAAVFVSKLDR--PIDPRG-----
MMAR_3480|M.marinum_M LLAKLGMERRTQAAVFASRLGQ--GTRPVQGD---
MAV_4109|M.avium_104 LLAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
MAB_1522|M.abscessus_ATCC_1997 IFVKLDLRDRAAAIVYAYDHGIVTPK---------
Mvan_1515|M.vanbaalenii_PYR-1 ARAKYAGVGRPAPTKSALLARAIEDGILSLNDLY-
Mflv_4904|M.gilvum_PYR-GCK ARAKYAGVGRPASTKSALLARAIEDGILSLKDLY-
MSMEG_1197|M.smegmatis_MC2_155 IRAKYAAVGRPATTKAALVARAIQDGLIDVDDL--
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