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SREDDTRRPVRIAIIDDHDVVHAGIQAWCAEADPPIDLADSFQRPDEYFAKYPDAADDVDVVLLDLQIEG NRPDFDALSKLAASGRRVIVYSHITADEVILTCLELGAVTYLVKSEGKRHLIEAVHSAHTSTPYVGPRMG KAMLNDSTMGRIKLTDREKQVLIAWFQTESKDLVAERLFIAPTTVRTHLQRARAKYAGVGRPASTKSALL ARAIEDGILSLKDLY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4904 | - | - | 100% (226) | two component LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5014 | - | 7e-16 | 27.36% (212) | two component LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3847 | - | 9e-11 | 24.65% (215) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 2e-12 | 27.44% (215) | two component transcriptional regulatory protein DevR |
| M. tuberculosis H37Rv | Rv3133c | devR | 2e-12 | 27.44% (215) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1522 | - | 1e-09 | 24.78% (226) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_1516 | devR | 6e-12 | 26.15% (218) | two-component transcriptional regulatory protein DevR |
| M. avium 104 | MAV_4114 | - | 1e-09 | 26.64% (229) | response regulator receiver domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1197 | - | 3e-24 | 63.86% (83) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3184 | - | 2e-12 | 26.46% (223) | PUTATIVE two component transcriptional regulator, LuxR family |
| M. ulcerans Agy99 | MUL_2423 | devR | 4e-12 | 26.15% (218) | two component transcriptional regulatory protein DevR |
| M. vanbaalenii PYR-1 | Mvan_1515 | - | 1e-106 | 82.74% (226) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3157c|M.bovis_AF2122/97 ---------MVKVFLVDDHEVVRRGLVDLLGADPE-LDVVGEAGSVAEAM
Rv3133c|M.tuberculosis_H37Rv ---------MVKVFLVDDHEVVRRGLVDLLGADPE-LDVVGEAGSVAEAM
MMAR_1516|M.marinum_M ---------MVTVFLVDDHEVVRRGLIDLLDADPQ-LDVVGEAGSVSEAM
MUL_2423|M.ulcerans_Agy99 ---------MVTVFLVDDHEVVRRGLIDLLDADPQ-LDVVGEAGSVSEAM
MAV_4114|M.avium_104 ---MTDDATPTTVMVVDDHPIWRDAVARDL-AESG-FAVVATADGVATAQ
MAB_1522|M.abscessus_ATCC_1997 -----MTDTEVGVLLVDDQELVRTGLRRILRRKDG-FAIVGECADGSEVA
TH_3184|M.thermoresistible__bu -MEPVAAPSPVRIVLVDDHEMVIEGLKAMLAAFEDRVCVVGHAVGAERAV
Mflv_4904|M.gilvum_PYR-GCK MSREDDTRRPVRIAIIDDHDVVHAGIQAWCAEADPPIDLADSFQRPDEYF
Mvan_1515|M.vanbaalenii_PYR-1 MSRKDGARRAVRIAIIDDHDVVHAGIRAWCEEADPPIELVGSFLRPSEYF
MSMEG_1197|M.smegmatis_MC2_155 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 ARVPAARPDVAVLDVRLP-DGNGIELCRDLLSRMPDLRCLILTSYTSDEA
Rv3133c|M.tuberculosis_H37Rv ARVPAARPDVAVLDVRLP-DGNGIELCRDLLSRMPDLRCLILTSYTSDEA
MMAR_1516|M.marinum_M ARIPAANPDVAVLDVRLP-DGDGIELCRDLLSRMPNLRCLILTSYTSDEA
MUL_2423|M.ulcerans_Agy99 ARIPAANPDVAVLDVRLP-DGDGIELCRDLLSRMPNLRCLILTSYTSDEA
MAV_4114|M.avium_104 RRAGVVRPDVVVMDMQLP-DGDGAQATAAVLAVSPSSRVLVLSASDERDD
MAB_1522|M.abscessus_ATCC_1997 AAVSRARPDVVIMDLRMK-QMSGIEAIR-LLHAAQGPPALALTTFDDDEL
TH_3184|M.thermoresistible__bu EVVAELDPDIVLCDVRMQ-NTSGLDLCLTLREQAPHRKVVMLSVYDDEQY
Mflv_4904|M.gilvum_PYR-GCK AKYPDAADDVDVVLLDLQIEGNRPDFDALSKLAASGRRVIVYSHITADEV
Mvan_1515|M.vanbaalenii_PYR-1 SKYPTATDQVDVVLFDVQIEGNRPDFDTLSKLAERDQPVVVYSHITTDEV
MSMEG_1197|M.smegmatis_MC2_155 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 MLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLRG
Rv3133c|M.tuberculosis_H37Rv MLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLRG
MMAR_1516|M.marinum_M MLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALMSRLRG
MUL_2423|M.ulcerans_Agy99 MLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALMSRLRG
MAV_4114|M.avium_104 VLQAVKAGAAGYLVKSASKAELAQAVTDTAAGRAVFTPSLAGLVLGEYRR
MAB_1522|M.abscessus_ATCC_1997 LSGALRAGAAGFILKDSPAEELVRAVHAVARGEAYLDPAVTSRVLNAYRR
TH_3184|M.thermoresistible__bu LYQALRVGASGYLLKSISSDELVRQLEMVHRGQTALDPGMAARAVDTAAR
Mflv_4904|M.gilvum_PYR-GCK ILTCLELGAVTYLVKSEGKRHLIEAVHSAHTSTPYVGPRMGKAMLNDSTM
Mvan_1515|M.vanbaalenii_PYR-1 ILTSLDLGAITYLVKSEGRRHLIEAIHAAHTDTPYVGPRMGNAMLNDSTV
MSMEG_1197|M.smegmatis_MC2_155 ----------------------------------------MTAMPVDRPL
Mb3157c|M.bovis_AF2122/97 AAEKQD---PLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVS
Rv3133c|M.tuberculosis_H37Rv AAEKQD---PLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVS
MMAR_1516|M.marinum_M VVERPD---PLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVS
MUL_2423|M.ulcerans_Agy99 VVERPD---PLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVS
MAV_4114|M.avium_104 IAQSKDDGPTRPRLTDRETEVLRYVAKGLSAKQIAEKLSLSHRTVENHVQ
MAB_1522|M.abscessus_ATCC_1997 APAAVSG-DAQDKLTARELDVLALIASGATNSEIAEQLVISEVTVKSHIG
TH_3184|M.thermoresistible__bu LQRDEFWPGARHGLTQRESEILSYVVNGLSNRGIAAKLVIGDETVKSHLR
Mflv_4904|M.gilvum_PYR-GCK G---------RIKLTDREKQVLIAWFQTESKDLVAERLFIAPTTVRTHLQ
Mvan_1515|M.vanbaalenii_PYR-1 G---------RIKLTDREKQVLVAWFQTESKDLVAKRLFIAPSTVRTHLQ
MSMEG_1197|M.smegmatis_MC2_155 P---------RPELAPREKEVLLAWIRTDSKDGVARQLHIAPTTVRTHLQ
*: :* :* : :* :: :. **..::
Mb3157c|M.bovis_AF2122/97 RLLAKLGMERRTQAAVFATELKRSRPPGDGP----
Rv3133c|M.tuberculosis_H37Rv RLLAKLGMERRTQAAVFATELKRSRPPGDGP----
MMAR_1516|M.marinum_M RLLAKLGMERRTQAAVFAAELKRARSAGHR-----
MUL_2423|M.ulcerans_Agy99 RLLAKLGMERRTQAAVFAAELKRARSAGHR-----
MAV_4114|M.avium_104 ATFRKLQVANRVELARYAIEHGLDEEP--------
MAB_1522|M.abscessus_ATCC_1997 RIFVKLDLRDRAAAIVYAYDHGIVTPK--------
TH_3184|M.thermoresistible__bu SIYRKLGVSDRAAAVATALREGIYQ----------
Mflv_4904|M.gilvum_PYR-GCK RARAKYAGVGRPASTKSALLARAIEDGILSLKDLY
Mvan_1515|M.vanbaalenii_PYR-1 RARAKYAGVGRPAPTKSALLARAIEDGILSLNDLY
MSMEG_1197|M.smegmatis_MC2_155 RIRAKYAAVGRPATTKAALVARAIQDGLIDVDDL-
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