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LMSIDTAYMREAMARRLLRRGVSSGKITLPAVPGLVDEYVSVCNKIFGALGRKFSGDELDHLRSLLAKEL ANAYAGSNRSNIVITYDAPVGTVLNYFIQPQVSTLEESYDSWVASRKPPLFGINPDARVTALSTEITSPE TARVLDIGAGTGRNALALARRGHPVDAVELTPKFAEILRTEAFKHLLNIRVIDRDVFETMDDLQKDYQLI VLSEVVSDFRNVAQLRAIFELAAGCLAPGGRLVFNTFMPRPGYLSDDAVRELADAARELGQQVYTTIFTG EEIDIASAGLSLRLMTNDSVYEYEKENLPAGHWPPTGWYAEWVSGQDIFDVPREQSPVDMRWLVYQKTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1267 | - | - | 100% (350) | methyltransferase type 12 |
| M. vanbaalenii PYR-1 | Mvan_4027 | - | 4e-05 | 29.37% (143) | methyltransferase type 12 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2446 | - | 1e-113 | 57.31% (342) | hypothetical protein Mb2446 |
| M. gilvum PYR-GCK | Mflv_5088 | - | 1e-163 | 78.74% (348) | methyltransferase type 12 |
| M. tuberculosis H37Rv | Rv2423 | - | 1e-113 | 57.31% (342) | hypothetical protein Rv2423 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3750 | - | 1e-118 | 59.31% (349) | hypothetical protein MMAR_3750 |
| M. avium 104 | MAV_2748 | - | 1e-100 | 51.16% (346) | hypothetical protein MAV_2748 |
| M. smegmatis MC2 155 | MSMEG_2067 | - | 1e-05 | 26.35% (167) | methyltransferase type 12 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1436 | - | 2e-05 | 33.88% (121) | methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1267|M.vanbaalenii_PYR-1 ----MLMSIDTA-YMREAMARRLLRRGVSSGKITLPAVPGLVDEYVSVCN
Mflv_5088|M.gilvum_PYR-GCK ------MSIDTA-YMRDALTRRLLRRGVSGGTITLPAVPAMVDEYVSMCN
Mb2446|M.bovis_AF2122/97 MDNLPIESAESTRLAKAAMTRRFYTRSVVKGEITLPAVPSMIDEYVTMCA
Rv2423|M.tuberculosis_H37Rv MDNLPIESAESTRLAKAAMTRRFYTRSVVKGEITLPAVPSMIDEYVTMCA
MMAR_3750|M.marinum_M ---MPLSSVDSQQSLKNSMTRRFYSRSEVTGKITLPAVPAMIDEYVKMCD
MAV_2748|M.avium_104 MQDPPNRSFDPS-LLREAVIRRIYRRTSAEGTIRVPAVPAMIDEYLQLCG
MSMEG_2067|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1436|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1267|M.vanbaalenii_PYR-1 KIFGALGRKFSGDELDHLRSLLAKELANAYAGSNRSNIVITYDAPVGTVL
Mflv_5088|M.gilvum_PYR-GCK KIFAALGRRFNADELSHLRSLLAKELANAFDGSNRSNIVISYDAPIGNVL
Mb2446|M.bovis_AF2122/97 GLFAGVGRKFSDEELAHLRAVLQGQLAEAYAASQRSTIVISYNAPMGPTL
Rv2423|M.tuberculosis_H37Rv GLFAGVGRKFSDEELAHLRAVLQGQLAEAYAASQRSTIVISYNAPMGPTL
MMAR_3750|M.marinum_M GMFADVGRKFSEEELAHLRSVLEGQLAQAYSASPRSSIIISFNAPVGPTL
MAV_2748|M.avium_104 NVCATLSVWYAPEQFAQLRSALEVELAKAFKASPRSDVLISYHAPFGTGV
MSMEG_2067|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1436|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1267|M.vanbaalenii_PYR-1 NYFIQPQVSTLEESYDSWVASRKPPLFGINPDARVTALSTEITSPETARV
Mflv_5088|M.gilvum_PYR-GCK NYHIQPQWTSLADTYDNWVATRKPPLFGTHPDARVTTLAAEIADPTTARV
Mb2446|M.bovis_AF2122/97 HYQVRAQWRTVAQEYENWIATREPPLFGTEPDARVWALANEAADPTTHRV
Rv2423|M.tuberculosis_H37Rv HYQVRAQWRTVAQEYENWIATREPPLFGTEPDARVWALANEAADPTTHRV
MMAR_3750|M.marinum_M NYEVNARWWTVEAAYENWIDTRKPPLFGTEPDARVWALANEAADPSTHRV
MAV_2748|M.avium_104 NFHVQADWRTIEADYEQWVAVRPPPLFGTEPDARVLTLAAEADDPATYRV
MSMEG_2067|M.smegmatis_MC2_155 -----MDTTPTRELFDEAYESRTAPWVIGEPQP--AVVELERAGLIRSRV
MUL_1436|M.ulcerans_Agy99 --MVSGSAQDPSLSFGSAAAAYERGRPSYPPEAIDWLLPAGARD-----V
: . *:. : . *
Mvan_1267|M.vanbaalenii_PYR-1 LDIGAGTGRNALALARRGHPVDAVELTPKFAEILRTEAFKHLLNIRVIDR
Mflv_5088|M.gilvum_PYR-GCK LDIGAGTGRNALALAKKGHPVDAVELTPKFADILREEAYKHLLGVRVIDR
Mb2446|M.bovis_AF2122/97 LEIGAGTGRNALALARRGHPVDVVEMTPKFADIIRSDAERDSLDVRVIMR
Rv2423|M.tuberculosis_H37Rv LEIGAGTGRNALALARRGHPVDVVEMTPKFADIIRSDAERDSLDVRVIMR
MMAR_3750|M.marinum_M LEIGAGTGRNALALARRGHPVDVVELTPKFAEMIRADAEKEGLDVRVIVR
MAV_2748|M.avium_104 LDVGAGTGRNALALARRGHPVDAVEMTAKFAEAMRADAERESLGVNVIQS
MSMEG_2067|M.smegmatis_MC2_155 LDVGCGAGEHTILLTRLGYDVLGIDFSPQAIEMARENARGRGVDARFAVG
MUL_1436|M.ulcerans_Agy99 LDLGAGTGKLTTRLVERGLDVVAVDPIPEMLEVLRASLPR--------TL
*::*.*:*. : *.. * * :: .: : * .
Mvan_1267|M.vanbaalenii_PYR-1 DVFETMDDLQKDYQLIVLSEVVSDFRNVAQLRAIFELAAGCLAPGGR-LV
Mflv_5088|M.gilvum_PYR-GCK DIFETLDDLQKDYSLIILSEVTPDFRSPEQIRAVFELAAQCLAPGGR-LV
Mb2446|M.bovis_AF2122/97 DVFSTMDDLRQDYQLMVLSEVVPDFRTTQQLRNLFELAAQCLAPGAR-LV
Rv2423|M.tuberculosis_H37Rv DVFSTMDDLRQDYQLMVLSEVVPDFRTTQQLRNLFELAAQCLAPGAR-LV
MMAR_3750|M.marinum_M DVFTTIADLRRDYQLIVLSEVVSDFRTTQQLRELFELAAQCLAPGAR-LV
MAV_2748|M.avium_104 DVFTAMENTRDRYQLMVLSEVVPDFRTAHELRGMFELAAECLAPGGR-LV
MSMEG_2067|M.smegmatis_MC2_155 DAMALGDLGDGAYDTILDSALFHIFDDADRQTYVASLHAGCRPGGTV-HI
MUL_1436|M.ulcerans_Agy99 ALLGTAEEIPLEDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLV
: . : : : : .: . * :
Mvan_1267|M.vanbaalenii_PYR-1 FNTFMPRPGYLSDDAVRELADAARELGQQVYTTIFTGEEIDIASAGLSLR
Mflv_5088|M.gilvum_PYR-GCK FNVFMPRPGFMSDDAVNELADSARQLAQQVYSAIFFGDEIDTAGAGLPLR
Mb2446|M.bovis_AF2122/97 FNAFLANGDYAPD-------QAAREFGQQMYTGMCTRAEMSAAAAGLPLE
Rv2423|M.tuberculosis_H37Rv FNAFLANGDYAPD-------QAAREFGQQMYTGMCTRAEMSAAAAGLPLE
MMAR_3750|M.marinum_M FNAFLACGGYTPD-------QAAREFGQQAYTTIFTRHELSVAAAGLPVE
MAV_2748|M.avium_104 FNTFLARDGYVPD-------AAAVQFSQQCNSMVFTRDEVMGAAGGLPLA
MSMEG_2067|M.smegmatis_MC2_155 LALSDAGRGFGPE--------VSEEQIRKAFGDGWDLEALETTTYRGVVG
MUL_1436|M.ulcerans_Agy99 WNTRDERLGWVRELGRIIGRDSDPVRDKVTLPEPFTGVARHHVEWTNYLT
.: : : . :
Mvan_1267|M.vanbaalenii_PYR-1 LMTNDSVYEYEKENLPAGHWPPTGWYAEWVSGQDIFDVPREQSPVDMRWL
Mflv_5088|M.gilvum_PYR-GCK LMSNDSVYEFEKENLPPGAWPHTGWYAEWVSGQDIFDVPREQSPVEMRWL
Mb2446|M.bovis_AF2122/97 LVADDSVYDYEKTHLPPGAWPPTSWYADWIRGLDVFTTNVESCPIEMRWL
Rv2423|M.tuberculosis_H37Rv LVADDSVYDYEKTHLPPGAWPPTSWYADWIRGLDVFTTNVESCPIEMRWL
MMAR_3750|M.marinum_M LIADDSVYDYEKAHLPADAWPPTSWYADWVSGLDVFPVAREMSPIELRWL
MAV_2748|M.avium_104 LVADDSAYEYEKTHSPAESWPPTGWFEGWAGGLDVFDVERDDSPIELRWI
MSMEG_2067|M.smegmatis_MC2_155 PVHAEAIGLPVGTQVDEPAWLARARRL-----------------------
MUL_1436|M.ulcerans_Agy99 PQALIDLVASRSYCITSPAEVRTKTLDQVRELLATHPALANSAGLALPYV
Mvan_1267|M.vanbaalenii_PYR-1 VYQKTG----
Mflv_5088|M.gilvum_PYR-GCK VYQKTG----
Mb2446|M.bovis_AF2122/97 VFQRRR----
Rv2423|M.tuberculosis_H37Rv VFQRRR----
MMAR_3750|M.marinum_M VFRKTH----
MAV_2748|M.avium_104 VFAKTRAG--
MSMEG_2067|M.smegmatis_MC2_155 ----------
MUL_1436|M.ulcerans_Agy99 TVCVSATLAA