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MPLSSVDSQQSLKNSMTRRFYSRSEVTGKITLPAVPAMIDEYVKMCDGMFADVGRKFSEEELAHLRSVLE GQLAQAYSASPRSSIIISFNAPVGPTLNYEVNARWWTVEAAYENWIDTRKPPLFGTEPDARVWALANEAA DPSTHRVLEIGAGTGRNALALARRGHPVDVVELTPKFAEMIRADAEKEGLDVRVIVRDVFTTIADLRRDY QLIVLSEVVSDFRTTQQLRELFELAAQCLAPGARLVFNAFLACGGYTPDQAAREFGQQAYTTIFTRHELS VAAAGLPVELIADDSVYDYEKAHLPADAWPPTSWYADWVSGLDVFPVAREMSPIELRWLVFRKTH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3750 | - | - | 100% (345) | hypothetical protein MMAR_3750 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2446 | - | 1e-155 | 76.09% (343) | hypothetical protein Mb2446 |
| M. gilvum PYR-GCK | Mflv_5088 | - | 1e-115 | 57.35% (340) | methyltransferase type 12 |
| M. tuberculosis H37Rv | Rv2423 | - | 1e-155 | 76.09% (343) | hypothetical protein Rv2423 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_2748 | - | 1e-116 | 60.06% (333) | hypothetical protein MAV_2748 |
| M. smegmatis MC2 155 | MSMEG_2067 | - | 1e-06 | 26.77% (198) | methyltransferase type 12 |
| M. thermoresistible (build 8) | TH_3761 | - | 3e-06 | 30.47% (128) | PUTATIVE methyltransferase type 12 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1267 | - | 1e-118 | 59.31% (349) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2446|M.bovis_AF2122/97 MDNLPIESAESTRLAKAAMTRRFYTRSVVKGEITLPAVPSMIDEYVTMCA
Rv2423|M.tuberculosis_H37Rv MDNLPIESAESTRLAKAAMTRRFYTRSVVKGEITLPAVPSMIDEYVTMCA
MMAR_3750|M.marinum_M ---MPLSSVDSQQSLKNSMTRRFYSRSEVTGKITLPAVPAMIDEYVKMCD
Mflv_5088|M.gilvum_PYR-GCK ------MSID-TAYMRDALTRRLLRRGVSGGTITLPAVPAMVDEYVSMCN
Mvan_1267|M.vanbaalenii_PYR-1 ----MLMSID-TAYMREAMARRLLRRGVSSGKITLPAVPGLVDEYVSVCN
MAV_2748|M.avium_104 MQDPPNRSFD-PSLLREAVIRRIYRRTSAEGTIRVPAVPAMIDEYLQLCG
MSMEG_2067|M.smegmatis_MC2_155 --------------------------------------------------
TH_3761|M.thermoresistible__bu --------------------------------------------------
Mb2446|M.bovis_AF2122/97 GLFAGVGRKFSDEELAHLRAVLQGQLAEAYAASQRSTIVISYNAPMGPTL
Rv2423|M.tuberculosis_H37Rv GLFAGVGRKFSDEELAHLRAVLQGQLAEAYAASQRSTIVISYNAPMGPTL
MMAR_3750|M.marinum_M GMFADVGRKFSEEELAHLRSVLEGQLAQAYSASPRSSIIISFNAPVGPTL
Mflv_5088|M.gilvum_PYR-GCK KIFAALGRRFNADELSHLRSLLAKELANAFDGSNRSNIVISYDAPIGNVL
Mvan_1267|M.vanbaalenii_PYR-1 KIFGALGRKFSGDELDHLRSLLAKELANAYAGSNRSNIVITYDAPVGTVL
MAV_2748|M.avium_104 NVCATLSVWYAPEQFAQLRSALEVELAKAFKASPRSDVLISYHAPFGTGV
MSMEG_2067|M.smegmatis_MC2_155 --------------------------------------------------
TH_3761|M.thermoresistible__bu --------------------------------------------------
Mb2446|M.bovis_AF2122/97 HYQVRAQWRTVAQEYENWIATREPPLFGTEPDARVWALANEAADPTTHRV
Rv2423|M.tuberculosis_H37Rv HYQVRAQWRTVAQEYENWIATREPPLFGTEPDARVWALANEAADPTTHRV
MMAR_3750|M.marinum_M NYEVNARWWTVEAAYENWIDTRKPPLFGTEPDARVWALANEAADPSTHRV
Mflv_5088|M.gilvum_PYR-GCK NYHIQPQWTSLADTYDNWVATRKPPLFGTHPDARVTTLAAEIADPTTARV
Mvan_1267|M.vanbaalenii_PYR-1 NYFIQPQVSTLEESYDSWVASRKPPLFGINPDARVTALSTEITSPETARV
MAV_2748|M.avium_104 NFHVQADWRTIEADYEQWVAVRPPPLFGTEPDARVLTLAAEADDPATYRV
MSMEG_2067|M.smegmatis_MC2_155 -----MDTTPTRELFDEAYESRTAPWVIGEPQP--AVVELERAGLIRSRV
TH_3761|M.thermoresistible__bu ---MSSRRLLFRTLYRLGMTPWDGHPLAASLRGLVEGGVEGFEPLPPGAA
: . .
Mb2446|M.bovis_AF2122/97 LEIGAGTGRNALALARRGHPVDVVEMTPKFADIIRSDAERDSLDVRVIMR
Rv2423|M.tuberculosis_H37Rv LEIGAGTGRNALALARRGHPVDVVEMTPKFADIIRSDAERDSLDVRVIMR
MMAR_3750|M.marinum_M LEIGAGTGRNALALARRGHPVDVVELTPKFAEMIRADAEKEGLDVRVIVR
Mflv_5088|M.gilvum_PYR-GCK LDIGAGTGRNALALAKKGHPVDAVELTPKFADILREEAYKHLLGVRVIDR
Mvan_1267|M.vanbaalenii_PYR-1 LDIGAGTGRNALALARRGHPVDAVELTPKFAEILRTEAFKHLLNIRVIDR
MAV_2748|M.avium_104 LDVGAGTGRNALALARRGHPVDAVEMTAKFAEAMRADAERESLGVNVIQS
MSMEG_2067|M.smegmatis_MC2_155 LDVGCGAGEHTILLTRLGYDVLGIDFSPQAIEMARENARGRGVDARFAVG
TH_3761|M.thermoresistible__bu LDLGCGTGDSSIYLARHGWMVTGVDYIEKPLHKARAKAEAQGVDVHFLQA
*::*.*:* :: *:: * * :: : . * .* :. ..
Mb2446|M.bovis_AF2122/97 DVFSTMDDLR-----QDYQLMVLSEVVPDFRTTQQLRNLFELAAQCLAPG
Rv2423|M.tuberculosis_H37Rv DVFSTMDDLR-----QDYQLMVLSEVVPDFRTTQQLRNLFELAAQCLAPG
MMAR_3750|M.marinum_M DVFTTIADLR-----RDYQLIVLSEVVSDFRTTQQLRELFELAAQCLAPG
Mflv_5088|M.gilvum_PYR-GCK DIFETLDDLQ-----KDYSLIILSEVTPDFRSPEQIRAVFELAAQCLAPG
Mvan_1267|M.vanbaalenii_PYR-1 DVFETMDDLQ-----KDYQLIVLSEVVSDFRNVAQLRAIFELAAGCLAPG
MAV_2748|M.avium_104 DVFTAMENTR-----DRYQLMVLSEVVPDFRTAHELRGMFELAAECLAPG
MSMEG_2067|M.smegmatis_MC2_155 DAMALGDLGD-----GAYDTILDSALFHIFDDADRQTYVASLHAGCRPGG
TH_3761|M.thermoresistible__bu DVTRLRQDVSPDVVGAGFDLIIDNGCLHGMSAEDRDAYVREVTAVA-APD
* :. :: . : . : .: * . . .
Mb2446|M.bovis_AF2122/97 ARLVFNAFLANGDYAPD-------QAAREFGQQMYTGMCTRAEMSAAAAG
Rv2423|M.tuberculosis_H37Rv ARLVFNAFLANGDYAPD-------QAAREFGQQMYTGMCTRAEMSAAAAG
MMAR_3750|M.marinum_M ARLVFNAFLACGGYTPD-------QAAREFGQQAYTTIFTRHELSVAAAG
Mflv_5088|M.gilvum_PYR-GCK GRLVFNVFMPRPGFMSDDAVNELADSARQLAQQVYSAIFFGDEIDTAGAG
Mvan_1267|M.vanbaalenii_PYR-1 GRLVFNTFMPRPGYLSDDAVRELADAARELGQQVYTTIFTGEEIDIASAG
MAV_2748|M.avium_104 GRLVFNTFLARDGYVPD-------AAAVQFSQQCNSMVFTRDEVMGAAGG
MSMEG_2067|M.smegmatis_MC2_155 TVHILALSDAGRGFGPE--------VSEEQIRKAFGDGWDLEALETTTYR
TH_3761|M.thermoresistible__bu ARLHIVAFTPGGLFGVP-------GITPEEVEQRFSADWTLLSSGVEAES
: . : : : .:
Mb2446|M.bovis_AF2122/97 LPLELVADDSVYDYEKTHLPPGAWPPTSWYADWIRGLDVFTTNVESCPIE
Rv2423|M.tuberculosis_H37Rv LPLELVADDSVYDYEKTHLPPGAWPPTSWYADWIRGLDVFTTNVESCPIE
MMAR_3750|M.marinum_M LPVELIADDSVYDYEKAHLPADAWPPTSWYADWVSGLDVFPVAREMSPIE
Mflv_5088|M.gilvum_PYR-GCK LPLRLMSNDSVYEFEKENLPPGAWPHTGWYAEWVSGQDIFDVPREQSPVE
Mvan_1267|M.vanbaalenii_PYR-1 LSLRLMTNDSVYEYEKENLPAGHWPPTGWYAEWVSGQDIFDVPREQSPVD
MAV_2748|M.avium_104 LPLALVADDSAYEYEKTHSPAESWPPTGWFEGWAGGLDVFDVERDDSPIE
MSMEG_2067|M.smegmatis_MC2_155 GVVGPVHAEAIGLPVGTQVDEPAWLARARRL-------------------
TH_3761|M.thermoresistible__bu ARGNQASRYYLFAASRRRTA------------------------------
.
Mb2446|M.bovis_AF2122/97 MRWLVFQRRR--
Rv2423|M.tuberculosis_H37Rv MRWLVFQRRR--
MMAR_3750|M.marinum_M LRWLVFRKTH--
Mflv_5088|M.gilvum_PYR-GCK MRWLVYQKTG--
Mvan_1267|M.vanbaalenii_PYR-1 MRWLVYQKTG--
MAV_2748|M.avium_104 LRWIVFAKTRAG
MSMEG_2067|M.smegmatis_MC2_155 ------------
TH_3761|M.thermoresistible__bu ------------