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VDNLPIESAESTRLAKAAMTRRFYTRSVVKGEITLPAVPSMIDEYVTMCAGLFAGVGRKFSDEELAHLRA VLQGQLAEAYAASQRSTIVISYNAPMGPTLHYQVRAQWRTVAQEYENWIATREPPLFGTEPDARVWALAN EAADPTTHRVLEIGAGTGRNALALARRGHPVDVVEMTPKFADIIRSDAERDSLDVRVIMRDVFSTMDDLR QDYQLMVLSEVVPDFRTTQQLRNLFELAAQCLAPGARLVFNAFLANGDYAPDQAAREFGQQMYTGMCTRA EMSAAAAGLPLELVADDSVYDYEKTHLPPGAWPPTSWYADWIRGLDVFTTNVESCPIEMRWLVFQRRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2423 | - | - | 100% (348) | hypothetical protein Rv2423 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2446 | - | 0.0 | 100.00% (348) | hypothetical protein Mb2446 |
| M. gilvum PYR-GCK | Mflv_5088 | - | 1e-116 | 57.31% (342) | methyltransferase type 12 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3750 | - | 1e-155 | 76.09% (343) | hypothetical protein MMAR_3750 |
| M. avium 104 | MAV_2748 | - | 1e-113 | 57.91% (335) | hypothetical protein MAV_2748 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1267 | - | 1e-113 | 57.31% (342) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2423|M.tuberculosis_H37Rv MDNLPIESAESTRLAKAAMTRRFYTRSVVKGEITLPAVPSMIDEYVTMCA
Mb2446|M.bovis_AF2122/97 MDNLPIESAESTRLAKAAMTRRFYTRSVVKGEITLPAVPSMIDEYVTMCA
MMAR_3750|M.marinum_M ---MPLSSVDSQQSLKNSMTRRFYSRSEVTGKITLPAVPAMIDEYVKMCD
MAV_2748|M.avium_104 MQDPPNRSFDPS-LLREAVIRRIYRRTSAEGTIRVPAVPAMIDEYLQLCG
Mflv_5088|M.gilvum_PYR-GCK ------MSIDTA-YMRDALTRRLLRRGVSGGTITLPAVPAMVDEYVSMCN
Mvan_1267|M.vanbaalenii_PYR-1 ----MLMSIDTA-YMREAMARRLLRRGVSSGKITLPAVPGLVDEYVSVCN
* :. : :: **: * * * :****.::***: :*
Rv2423|M.tuberculosis_H37Rv GLFAGVGRKFSDEELAHLRAVLQGQLAEAYAASQRSTIVISYNAPMGPTL
Mb2446|M.bovis_AF2122/97 GLFAGVGRKFSDEELAHLRAVLQGQLAEAYAASQRSTIVISYNAPMGPTL
MMAR_3750|M.marinum_M GMFADVGRKFSEEELAHLRSVLEGQLAQAYSASPRSSIIISFNAPVGPTL
MAV_2748|M.avium_104 NVCATLSVWYAPEQFAQLRSALEVELAKAFKASPRSDVLISYHAPFGTGV
Mflv_5088|M.gilvum_PYR-GCK KIFAALGRRFNADELSHLRSLLAKELANAFDGSNRSNIVISYDAPIGNVL
Mvan_1267|M.vanbaalenii_PYR-1 KIFGALGRKFSGDELDHLRSLLAKELANAYAGSNRSNIVITYDAPVGTVL
: . :. : ::: :**: * :**:*: .* ** ::*::.**.* :
Rv2423|M.tuberculosis_H37Rv HYQVRAQWRTVAQEYENWIATREPPLFGTEPDARVWALANEAADPTTHRV
Mb2446|M.bovis_AF2122/97 HYQVRAQWRTVAQEYENWIATREPPLFGTEPDARVWALANEAADPTTHRV
MMAR_3750|M.marinum_M NYEVNARWWTVEAAYENWIDTRKPPLFGTEPDARVWALANEAADPSTHRV
MAV_2748|M.avium_104 NFHVQADWRTIEADYEQWVAVRPPPLFGTEPDARVLTLAAEADDPATYRV
Mflv_5088|M.gilvum_PYR-GCK NYHIQPQWTSLADTYDNWVATRKPPLFGTHPDARVTTLAAEIADPTTARV
Mvan_1267|M.vanbaalenii_PYR-1 NYFIQPQVSTLEESYDSWVASRKPPLFGINPDARVTALSTEITSPETARV
:: :.. :: *:.*: * ***** .***** :*: * .* * **
Rv2423|M.tuberculosis_H37Rv LEIGAGTGRNALALARRGHPVDVVEMTPKFADIIRSDAERDSLDVRVIMR
Mb2446|M.bovis_AF2122/97 LEIGAGTGRNALALARRGHPVDVVEMTPKFADIIRSDAERDSLDVRVIMR
MMAR_3750|M.marinum_M LEIGAGTGRNALALARRGHPVDVVELTPKFAEMIRADAEKEGLDVRVIVR
MAV_2748|M.avium_104 LDVGAGTGRNALALARRGHPVDAVEMTAKFAEAMRADAERESLGVNVIQS
Mflv_5088|M.gilvum_PYR-GCK LDIGAGTGRNALALAKKGHPVDAVELTPKFADILREEAYKHLLGVRVIDR
Mvan_1267|M.vanbaalenii_PYR-1 LDIGAGTGRNALALARRGHPVDAVELTPKFAEILRTEAFKHLLNIRVIDR
*::************::*****.**:*.***: :* :* :. *.:.**
Rv2423|M.tuberculosis_H37Rv DVFSTMDDLRQDYQLMVLSEVVPDFRTTQQLRNLFELAAQCLAPGARLVF
Mb2446|M.bovis_AF2122/97 DVFSTMDDLRQDYQLMVLSEVVPDFRTTQQLRNLFELAAQCLAPGARLVF
MMAR_3750|M.marinum_M DVFTTIADLRRDYQLIVLSEVVSDFRTTQQLRELFELAAQCLAPGARLVF
MAV_2748|M.avium_104 DVFTAMENTRDRYQLMVLSEVVPDFRTAHELRGMFELAAECLAPGGRLVF
Mflv_5088|M.gilvum_PYR-GCK DIFETLDDLQKDYSLIILSEVTPDFRSPEQIRAVFELAAQCLAPGGRLVF
Mvan_1267|M.vanbaalenii_PYR-1 DVFETMDDLQKDYQLIVLSEVVSDFRNVAQLRAIFELAAGCLAPGGRLVF
*:* :: : : *.*::****..***. ::* :***** *****.****
Rv2423|M.tuberculosis_H37Rv NAFLANGDYAPD-------QAAREFGQQMYTGMCTRAEMSAAAAGLPLEL
Mb2446|M.bovis_AF2122/97 NAFLANGDYAPD-------QAAREFGQQMYTGMCTRAEMSAAAAGLPLEL
MMAR_3750|M.marinum_M NAFLACGGYTPD-------QAAREFGQQAYTTIFTRHELSVAAAGLPVEL
MAV_2748|M.avium_104 NTFLARDGYVPD-------AAAVQFSQQCNSMVFTRDEVMGAAGGLPLAL
Mflv_5088|M.gilvum_PYR-GCK NVFMPRPGFMSDDAVNELADSARQLAQQVYSAIFFGDEIDTAGAGLPLRL
Mvan_1267|M.vanbaalenii_PYR-1 NTFMPRPGYLSDDAVRELADAARELGQQVYTTIFTGEEIDIASAGLSLRL
*.*:. .: .* :* ::.** : : *: *..**.: *
Rv2423|M.tuberculosis_H37Rv VADDSVYDYEKTHLPPGAWPPTSWYADWIRGLDVFTTNVESCPIEMRWLV
Mb2446|M.bovis_AF2122/97 VADDSVYDYEKTHLPPGAWPPTSWYADWIRGLDVFTTNVESCPIEMRWLV
MMAR_3750|M.marinum_M IADDSVYDYEKAHLPADAWPPTSWYADWVSGLDVFPVAREMSPIELRWLV
MAV_2748|M.avium_104 VADDSAYEYEKTHSPAESWPPTGWFEGWAGGLDVFDVERDDSPIELRWIV
Mflv_5088|M.gilvum_PYR-GCK MSNDSVYEFEKENLPPGAWPHTGWYAEWVSGQDIFDVPREQSPVEMRWLV
Mvan_1267|M.vanbaalenii_PYR-1 MTNDSVYEYEKENLPAGHWPPTGWYAEWVSGQDIFDVPREQSPVDMRWLV
:::**.*::** : *. ** *.*: * * *:* . : .*:::**:*
Rv2423|M.tuberculosis_H37Rv FQRRR--
Mb2446|M.bovis_AF2122/97 FQRRR--
MMAR_3750|M.marinum_M FRKTH--
MAV_2748|M.avium_104 FAKTRAG
Mflv_5088|M.gilvum_PYR-GCK YQKTG--
Mvan_1267|M.vanbaalenii_PYR-1 YQKTG--
: :