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TRDHSGADDDRDRVIAAVHDELARWGIDRFDVGAMAHRHGLDVEAIRRRWPDPESLVLDALAERPGDDGA VPDTGSLRTDLFHLAGRMAAIVTSEAGRKLHGGHLIGDVHVASVEIRRSAWRSRAADLGVVFERARQRGE MAEDIDHFTVLELLFAPINMRALYTGEPIDDRYCRTIADLVYRAVSPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1163 | - | - | 100% (189) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1545 | - | 8e-29 | 38.64% (176) | hypothetical protein Mvan_1545 |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 8e-11 | 28.57% (168) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 3e-05 | 24.84% (157) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_5169 | - | 6e-77 | 73.89% (180) | hypothetical protein Mflv_5169 |
| M. tuberculosis H37Rv | Rv1556 | - | 3e-05 | 24.84% (157) | regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0300c | - | 2e-16 | 31.21% (173) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 3e-06 | 38.14% (97) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5165 | - | 5e-09 | 33.33% (159) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3410 | - | 6e-14 | 31.05% (190) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3283 | - | 2e-09 | 28.09% (178) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 8e-07 | 38.14% (97) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1163|M.vanbaalenii_PYR-1 ------MTRDHSGADD----DRDRVIAAVHDELARWGIDRFDVGAMAHRH
Mflv_5169|M.gilvum_PYR-GCK ------MQAERPLAAD----DHDRIVAAVHDEVARWGIDRFDVGAMAHRH
MSMEG_3410|M.smegmatis_MC2_155 --------MARPRDDS----ITEAVVDATRQLCGEIGYRNLTMEALAARA
MMAR_0340|M.marinum_M ----MVADFGRPRDPR----IDGAVLRATVELLAETGYAGLLVSAIAKRA
MUL_4780|M.ulcerans_Agy99 ----MVADFGRPRDPR----IDGAVLRATVELLAETGYAGLLVSAIAKRA
MAV_5165|M.avium_104 ------MDFGRPRDPR----IDAAVLRATVELLAETGYPGLLVSAIAQRA
TH_3283|M.thermoresistible__bu MPGSGARSPGRPRDPA----LDDAIRAAARDVVVEHGYDATTLALIADRA
Mb1581|M.bovis_AF2122/97 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASA
Rv1556|M.tuberculosis_H37Rv MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASA
MAB_0300c|M.abscessus_ATCC_199 -----MSTEKKPQIRG--VNLERAVLAATLAQIEAVGIEQTRIAEIAARA
:. : .. * : :*
Mvan_1163|M.vanbaalenii_PYR-1 GLDVEAIRRRWPDPESLVLDALAERPGDDGAVPDTGSLRTDLFHLAGRMA
Mflv_5169|M.gilvum_PYR-GCK GLDEPSIRRHWPEPESLLLHALALRPGDDGSLPDTGSLRTDLIALAQRMV
MSMEG_3410|M.smegmatis_MC2_155 GTTKPAIRRRWPSLRHVVVDAMT-RDNVSMAVPDTGSTRSDLIVLVEELR
MMAR_0340|M.marinum_M GTSKPAIYRRWPSKAHLVHEAVFPIDAAT-AVPDTGSPVDDLREMVRRTT
MUL_4780|M.ulcerans_Agy99 GTSKPAIYRRWPSKAHLVHEAVFPIDAAT-AVPDTGSPVDDLREMVRRTT
MAV_5165|M.avium_104 GTSKPAIYRRWPSKAHLVHEAVFPVGADT-AIPDTGSTADDLREMVRRTM
TH_3283|M.thermoresistible__bu GVSVPTIYRRWQHKHELIEEAVLHLDTFE-LPEPTGDLEADLGTWVRLFL
Mb1581|M.bovis_AF2122/97 RASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELIC
Rv1556|M.tuberculosis_H37Rv RASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELIC
MAB_0300c|M.abscessus_ATCC_199 GVHETSIYRRWKTLPRLLADALIIHIDADIPIPDTGSLREDLMSLARGLA
:: *:* :: *. **. **
Mvan_1163|M.vanbaalenii_PYR-1 AIVTSEAGRKLHGGHLIGDVHVASVEIR--RSAWRSRAADLGVVFERARQ
Mflv_5169|M.gilvum_PYR-GCK ALITSDEGRKLHGGHLIADTFVASMDVR--RSAWRARAASLAGVFERARE
MSMEG_3410|M.smegmatis_MC2_155 VSMGDVMLGRILPALVVDLSDDGDLRRRFLDSVWRPRRERADRILRRGVE
MMAR_0340|M.marinum_M AVLSTPAAKAALPGLIGEMAADPTLHSALLVRFGEIFGHGLTTWLDNAAA
MUL_4780|M.ulcerans_Agy99 AVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEIFGHGLTTWLDNAAA
MAV_5165|M.avium_104 VFLTTPAAKAALPGLIGEMAADPSLHSALLERFAGAIGGGLADWLAAAAA
TH_3283|M.thermoresistible__bu TVAMEPAARAAVPGLMSAYSRNPDDYRRLMTRGELPVRAAIAAMLERAKA
Mb1581|M.bovis_AF2122/97 REVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAVD
Rv1556|M.tuberculosis_H37Rv REVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAVD
MAB_0300c|M.abscessus_ATCC_199 QFLETPHGDALMRGTVQVSDDPEVAEAR--REFWNRRLTAVEAIVQRALV
. : . .
Mvan_1163|M.vanbaalenii_PYR-1 RGEMAEDIDHFTVLELLFAPINMRALYTGEPID----DRYCRTIADLVYR
Mflv_5169|M.gilvum_PYR-GCK RGELRAGVDHITALEMLFAPINMRALYTGEDID----DAYCEQIADMVYR
MSMEG_3410|M.smegmatis_MC2_155 RGELRADLDFELAQDLLAATVIYRFLFAHADLD----PALSEHIVDYVLR
MMAR_0340|M.marinum_M RGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAWIDRTTTLLLK
MUL_4780|M.ulcerans_Agy99 RGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAWIDRTTTLLLK
MAV_5165|M.avium_104 RGEARPDVTAAELAETIAGVTLVALLTRPTELD----DAWVDRTTRLLLK
TH_3283|M.thermoresistible__bu AGQAAPDCDPDAVFELIRGATFLRALTHSDEDA----EAFCTRITEAVLR
Mb1581|M.bovis_AF2122/97 RGEISSAAISDELWDLLPGYLIFRSIIPNRPPT---QDTVQALVDDVILP
Rv1556|M.tuberculosis_H37Rv RGEISSAAISDELWDLLPGYLIFRSIIPNRPPT---QDTVQALVDDVILP
MAB_0300c|M.abscessus_ATCC_199 RGEVRPGVDARTVVLTLGGYVHLWAAHLGQTAD----DLALDELVDLIID
*: : . :
Mvan_1163|M.vanbaalenii_PYR-1 AVSPA-----
Mflv_5169|M.gilvum_PYR-GCK AVSA------
MSMEG_3410|M.smegmatis_MC2_155 GIAAGPTESS
MMAR_0340|M.marinum_M GIRKGTPQ--
MUL_4780|M.ulcerans_Agy99 GIRKGTPQ--
MAV_5165|M.avium_104 GISA------
TH_3283|M.thermoresistible__bu AVRS------
Mb1581|M.bovis_AF2122/97 SLTRSTG---
Rv1556|M.tuberculosis_H37Rv SLTRSTG---
MAB_0300c|M.abscessus_ATCC_199 GVSAGR----
.: