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SDVDASQRATAIEAALAELQQWGVDRFSIEGVAQRSRLDAEYLHEQWTSERQLIIDALLSYSDTIISVPD TGSLQGDLTELAMAIAAYVNQPMGRRIARMMVVDTKSHTADYGTRSQFWTMRTEAIEVIFSRAAERGELR DDVRPSIALQLLTCPLHTFALYTDRSVDPGYCREIAELVTRAVQR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1545 | - | - | 100% (186) | hypothetical protein Mvan_1545 |
| M. vanbaalenii PYR-1 | Mvan_1163 | - | 8e-29 | 38.64% (176) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5902 | - | 8e-10 | 27.01% (174) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 3e-09 | 28.15% (135) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_4883 | - | 2e-63 | 61.62% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 3e-09 | 28.15% (135) | regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0300c | - | 4e-18 | 30.06% (173) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1695 | - | 8e-11 | 26.87% (134) | regulatory protein |
| M. avium 104 | MAV_4754 | - | 1e-09 | 24.34% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5340 | - | 5e-14 | 30.05% (183) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3283 | - | 4e-06 | 24.16% (178) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1934 | - | 5e-11 | 26.87% (134) | regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1581|M.bovis_AF2122/97 MVGAVTQIADRPTDPSPWS------PRETELLAVTLRLLQEHGYDRLTVD
Rv1556|M.tuberculosis_H37Rv MVGAVTQIADRPTDPSPWS------PRETELLAVTLRLLQEHGYDRLTVD
MMAR_1695|M.marinum_M ----MTQTADRSAQVSPWS------PREAELLAVTLQLLQEHGYDRLTID
MUL_1934|M.ulcerans_Agy99 -MGAMTQTADRSAQVSPWS------PREAELLAVTLQLLQEHGYDRLTID
Mvan_1545|M.vanbaalenii_PYR-1 -------MSDVDA------------SQRATAIEAALAELQQWGVDRFSIE
Mflv_4883|M.gilvum_PYR-GCK -------MSDNDE------------SRRAAAIEAALDEVQQWGVDRFRLE
MAB_0300c|M.abscessus_ATCC_199 -------MSTEKKPQIRGV------NLERAVLAATLAQIEAVGIEQTRIA
MAV_4754|M.avium_104 MGQPQSQMEPESKLRQRTEG-RLDRSRDPAILDAALAALAEHGYDATNMN
MSMEG_5340|M.smegmatis_MC2_155 -------MAEKSAPRRTSGGPVLLDDVTTAIEKAFFEELAAVGYGRLSVD
TH_3283|M.thermoresistible__bu ----MPGSGARSPGRPRDP------ALDDAIRAAARDVVVEHGYDATTLA
. : * :
Mb1581|M.bovis_AF2122/97 AVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA--VPPNTGNLRDDL
Rv1556|M.tuberculosis_H37Rv AVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA--VPPNTGNLRDDL
MMAR_1695|M.marinum_M AVANTARASKATVYRRWPSKAELVLAAFIEGVRQVA--VAPNTGSLRDDL
MUL_1934|M.ulcerans_Agy99 AVANTARASKATVYRRWPSKAELVLAAFIEGVRQVA--VAPNTGSLRDDL
Mvan_1545|M.vanbaalenii_PYR-1 GVAQRSRLDAEYLHEQWTSERQLIIDALLSYSDTII--SVPDTGSLQGDL
Mflv_4883|M.gilvum_PYR-GCK GVAHRAKLSPDYVRQIWGSETELIAEALLSYSQAMM--ELPDTGSLHGDL
MAB_0300c|M.abscessus_ATCC_199 EIAARAGVHETSIYRRWKTLPRLLADALIIHIDADI--PIPDTGSLREDL
MAV_4754|M.avium_104 DIAARAGVGKAAIYRRWSSKAALMTDALIYWRPELLNDDAPDTGSLAGDL
MSMEG_5340|M.smegmatis_MC2_155 AVARRAGVGKAAIYRRWRSKQALAADLVAKVAVTAI--DVPDTGSLRGDI
TH_3283|M.thermoresistible__bu LIADRAGVSVPTIYRRWQHKHELIEEAVLHLDTFEL---PEPTGDLEADL
:* : : . * * . **.* *:
Mb1581|M.bovis_AF2122/97 LRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRKALIQ
Rv1556|M.tuberculosis_H37Rv LRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRKALIQ
MMAR_1695|M.marinum_M VKIGEGICGQAHQQAS--TIRAVLVEVSRHPALSDALQRQFVDQRKALIQ
MUL_1934|M.ulcerans_Agy99 VKIGEGICGQAHQQAS--TIRAVLVEVSRHPALSDALQRQFVDQRKALIQ
Mvan_1545|M.vanbaalenii_PYR-1 TELAMAIAAYVNQPMGR-RIARMMVVDTKSHTADYGTRSQFWTMRTEAIE
Mflv_4883|M.gilvum_PYR-GCK TGLALALADYLNEPVGR-RISRMLVIDSKSQAVDRDTRARFWTVRRAIVE
MAB_0300c|M.abscessus_ATCC_199 MSLARGLAQFLETPHGD-ALMRGTVQVSDDPEVAEARR-EFWNRRLTAVE
MAV_4754|M.avium_104 DAIVKRAKRNDNALISNDLVLRVALEAAHDPELATALNDLILFKGRRVLS
MSMEG_5340|M.smegmatis_MC2_155 REYLRNGREALTHRLARKIIPDLIAEAVRDPEYGALLTDLIREPRRGRGS
TH_3283|M.thermoresistible__bu GTWVRLFLTVAMEPAARAAVPGLMSAYSRNPDDYRRLMTRGELPVRAAIA
. :
Mb1581|M.bovis_AF2122/97 YILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVD
Rv1556|M.tuberculosis_H37Rv YILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVD
MMAR_1695|M.marinum_M QVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQLLVD
MUL_1934|M.ulcerans_Agy99 QVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQLLVD
Mvan_1545|M.vanbaalenii_PYR-1 VIFSRAAERGELRDDVRPSIALQLLTCPLHTFALYTDRSVDPGYCR-EIA
Mflv_4883|M.gilvum_PYR-GCK DIFRRAAERGELRDDVRHIVALQLLTSPLHTFALYSEDPIPPEYCR-LIA
MAB_0300c|M.abscessus_ATCC_199 AIVQRALVRGEVRPGVDARTVVLTLGGYVHLWAAHLG-QTADDLALDELV
MAV_4754|M.avium_104 AVLAQAADRGEIDPNRDWSLVADVLT-AMGLLRAISGQRVDGKFVRRVID
MSMEG_5340|M.smegmatis_MC2_155 HIFERAIERGEIAPDADIDVALDVLAGALYWRQSILQTTADDDYLDRLTE
TH_3283|M.thermoresistible__bu AMLERAKAAGQAAPDCDPDAVFELIRGATFLRALTHSDEDAEAFCTRITE
:. :* *: :
Mb1581|M.bovis_AF2122/97 DVILPSLTRSTG
Rv1556|M.tuberculosis_H37Rv DVILPSLTRSTG
MMAR_1695|M.marinum_M DFIMPGLTQATG
MUL_1934|M.ulcerans_Agy99 DFIMPGLTQATG
Mvan_1545|M.vanbaalenii_PYR-1 ELVTRAVQR---
Mflv_4883|M.gilvum_PYR-GCK DLVTRAIRAD--
MAB_0300c|M.abscessus_ATCC_199 DLIIDGVSAGR-
MAV_4754|M.avium_104 TLILPAVRAAPE
MSMEG_5340|M.smegmatis_MC2_155 VVLMAVGMGK--
TH_3283|M.thermoresistible__bu AVLRAVRS----
.: