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VESFDFRGMRIAYEHTGQGEPVIMLHNGGSSHAIWQDVANRLAGKYELFAFDLLGFGNSAKPGAGYTLDN YVAMLEEFVSSRGLEKVAVVGNCMGSAIALAFTDRHRDQVKALVLCNPLTESTFLGGWLGPFLWLRERMP GINRQVYRLLGRLKLTNGIGSVATLFQLGPRGRALKLHRNAELCGCYAATGQVESLLGVLDDLENYSVVD NLAPQQGFPPICTIWGLKNKIVSPEAGRRLNSTLHPARQEWLPDCGHLLMLERPDEVASIIDGFLQAPAE TQA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1079 | - | - | 100% (283) | alpha/beta hydrolase fold |
| M. vanbaalenii PYR-1 | Mvan_2912 | - | 3e-25 | 29.02% (286) | alpha/beta hydrolase fold |
| M. vanbaalenii PYR-1 | Mvan_4279 | - | 2e-24 | 29.41% (289) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1864c | - | 1e-14 | 25.91% (274) | haloalkane dehalogenase |
| M. gilvum PYR-GCK | Mflv_2367 | - | 4e-23 | 30.25% (281) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv1833c | - | 1e-14 | 25.91% (274) | haloalkane dehalogenase |
| M. leprae Br4923 | MLBr_02269 | - | 5e-09 | 26.10% (272) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_0139c | - | 2e-53 | 39.78% (279) | alpha/beta fold family hydrolase |
| M. marinum M | MMAR_2710 | - | 1e-12 | 24.45% (274) | haloalkane dehalogenase |
| M. avium 104 | MAV_4567 | - | 3e-26 | 28.37% (282) | dihydrolipoyllysine-residue acetyltransferase component of |
| M. smegmatis MC2 155 | MSMEG_2913 | - | 6e-14 | 26.30% (270) | hydrolase |
| M. thermoresistible (build 8) | TH_1972 | - | 4e-11 | 24.10% (278) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3358 | - | 1e-12 | 29.31% (116) | hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1079|M.vanbaalenii_PYR-1 --------MES------------------FDFRGMRIAYEHTG---QGE-
MAB_0139c|M.abscessus_ATCC_199 --------MTSA----------------RFTFRGDTLAYSRTG---TGP-
Mflv_2367|M.gilvum_PYR-GCK --------MTD---------------LRYLDLHGDRCAYRDEG---DGEE
MAV_4567|M.avium_104 --------MSE---------------LKFLELHGDRVAFRDQG---EGE-
MUL_3358|M.ulcerans_Agy99 --------MTERKRNLRPVREVTAPSLQFRTIHGYKRAFRIAG---SGP-
Mb1864c|M.bovis_AF2122/97 ----MSIDFTPDPQ-------LYPFESRWFDSSRGRIHYVDEG---TGP-
Rv1833c|M.tuberculosis_H37Rv ----MSIDFTPDPQ-------LYPFESRWFDSSRGRIHYVDEG---TGP-
MMAR_2710|M.marinum_M MGRQFTPDFTPDPK-------LYPFASRWFDSSRGRLHYIDEG---DGP-
MLBr_02269|M.leprae_Br4923 ---------------------------------MINLAYEDRG---TGE-
TH_1972|M.thermoresistible__bu ---------------------------------MSERAPIHLG---SGE-
MSMEG_2913|M.smegmatis_MC2_155 --------MRPDVDWN---------LTETFDTAEGVIRWQRLGSDSSGDE
* *
Mvan_1079|M.vanbaalenii_PYR-1 PVIMLHNGGSSHAIWQ--DVANRLAGKYELFAFDLLGFGNSAKPG-AGYT
MAB_0139c|M.abscessus_ATCC_199 PILFLHNGGSAKEIWT--RQVEVLRQRYEVICLDHLGYGESDMPE-RGYT
Mflv_2367|M.gilvum_PYR-GCK TLLLLHGMAGSSETWR--AVIPHLAKRYRVIAPDLLGHGSSAKPR-GDYS
MAV_4567|M.avium_104 VLLLIHGMAGSSETWR--SVIPPLAKKFRVIAPDLLGHGESAKPR-TDYS
MUL_3358|M.ulcerans_Agy99 AILLIHGIGDNSTTWT--GIHAKLAQRFTVIAPDLLGHGRSDKPR-ADYS
Mb1864c|M.bovis_AF2122/97 PILLCHGNPTWSFLYR--DIIVALRDRFRCVAPDYLGFGLSERPSGFGYQ
Rv1833c|M.tuberculosis_H37Rv PILLCHGNPTWSFLYR--DIIVALRDRFRCVAPDYLGFGLSERPSGFGYQ
MMAR_2710|M.marinum_M PILLCHGNPTWSFLYR--HIIVALRDHFRCIAPDYLGFGLSEHPGTFGYK
MLBr_02269|M.leprae_Br4923 PVVFIAGRGGAGRTWQPHQVPAFLAAGYRVITFDNRGIGATENTE--GFT
TH_1972|M.thermoresistible__bu PVLLLHPFMMSQSVWKDVAPRIAGTGRYEVYAPTMPGHNGGVKGR-FFLD
MSMEG_2913|M.smegmatis_MC2_155 PVVLVHGTPYSSYLWR--DIAPALAQHRSVYVFDLLGYGQSEQREGQDLT
::: : * .
Mvan_1079|M.vanbaalenii_PYR-1 LDNYVAMLEEFVSSRGLEKVAVVGNCMGSAIALAFTDRHRDQVKALVLCN
MAB_0139c|M.abscessus_ATCC_199 IDQHVERLSAFIEHLGHERISVVGNCMGSAMALLLADRRPELFDSLVLIN
Mflv_2367|M.gilvum_PYR-GCK LGAFAAWLRDLLDELGIRSVTVVGQSLGGGVAMQFVYQHPDYCRRLVLIS
MAV_4567|M.avium_104 LGAFAVWLRDFLDELGVSRATVVGHSLGGGVAMQFVYQHPDYAQRLILIS
MUL_3358|M.ulcerans_Agy99 IAAYANGMRDLLSVLDIERVTIIGHSLGGGVAMQFAYQFPQLVDRLILVG
Mb1864c|M.bovis_AF2122/97 IDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVRGVVLGN
Rv1833c|M.tuberculosis_H37Rv IDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVRGVVLGN
MMAR_2710|M.marinum_M VDEHAQVVGEFVDHLGLDNYLTMGQDWGGPISMAVAVERAERVRGIVLGN
MLBr_02269|M.leprae_Br4923 TQTMVADTAVLIESLGAVPARIVGVSMGSFIAQELMVARPELVRAAVLMA
TH_1972|M.thermoresistible__bu TAELADDMERRLDELGWDTAHIVGNSLGGWVAFELERRGRARTLTGIAPA
MSMEG_2913|M.smegmatis_MC2_155 IAAQARRLADLLEHWGLKRPSMIANDIGAAIALHASLVNGAAYRDLVIFD
. :. . :. *. :: :
Mvan_1079|M.vanbaalenii_PYR-1 PLTESTFLGGWLGPFLWLRERMPGINRQVYRLLGRLKLTNGIGSVATLFQ
MAB_0139c|M.abscessus_ATCC_199 PLSKNTARRGVLGWLLPLVSRFPTLSMAISR---RVRIPQALTNIVITVQ
Mflv_2367|M.gilvum_PYR-GCK ----SGGLGQDVGWTLRLLSAP-GSELLLPLIAPS--PVVRAGDRVRAWF
MAV_4567|M.avium_104 ----SGGLGPDVGWVLRLLSAP-GAELVLPVIAPT--PVLSVGNKLRSWL
MUL_3358|M.ulcerans_Agy99 ----AGGVTKDVNVVFRLASLPMGAEALALLRLPMVLPTVQLAGKVLGMA
Mb1864c|M.bovis_AF2122/97 ------------TWFWPADTLAMKAFSRVMSSPPVQYAILRRNFFVERLI
Rv1833c|M.tuberculosis_H37Rv ------------TWFWPADTLAMKAFSRVMSSPPVQYAILRRNFFVERLI
MMAR_2710|M.marinum_M ------------TWFWPADTLTMKAFSTVMSSLPMQYAILHHNFFVERLI
MLBr_02269|M.leprae_Br4923 TR----------GRLDRTRQFFHAAEAEFHDSG--IQLPSGYNAKVRLLE
TH_1972|M.thermoresistible__bu ------------GGWHRWSPAKYEIVGKFVLGFPVWAVAKLLGRRAARLP
MSMEG_2913|M.smegmatis_MC2_155 --------------AVTGSDWEMGLFHLVRRNAGVFEALPGYAHRALITS
Mvan_1079|M.vanbaalenii_PYR-1 LGPRG--RALKLHR--NAELCGCYAATGQVESLLGVLDDLENYSVVDNLA
MAB_0139c|M.abscessus_ATCC_199 FGPRNWLRGIRAPRPGTAQAGKGWSVRGRLAALAEMFCDQTSLGAVDEIR
Mflv_2367|M.gilvum_PYR-GCK SARNIQSPRGAEMWSAYASLSDAHTRHAFLRTLRSVVDYRGQAVSALNKL
MAV_4567|M.avium_104 RGAGIQSPRGAELWNAYSSLSDGETRQSFLKTLRSVVDYRGQAVSALNRL
MUL_3358|M.ulcerans_Agy99 LGSTALGQDLPNVLRILDDLPEPTASSAFTRTLRAVVDWRGQIVTMLDRC
Mb1864c|M.bovis_AF2122/97 PAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQILAARPLLARLAREV
Rv1833c|M.tuberculosis_H37Rv PAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQILAARPLLARLAREV
MMAR_2710|M.marinum_M PAGTTHRPSSAVMEHYRGVQPTASARVGVAEMPKQILAARPLLARLASEV
MLBr_02269|M.leprae_Br4923 NLSRKTLNDDVAVADWIAMFN------MWPIKSTPGLRCQTDVAPQNNRL
TH_1972|M.thermoresistible__bu IARQLAFVAVSAYPDGISDDD-LVQIIDDVTHCAAYYQLLVKALLLPGLM
MSMEG_2913|M.smegmatis_MC2_155 HLQRATHSGFRPGVLERYLQPWLGADGQAAFYRQYQQLSVDDTRVFEDKL
Mvan_1079|M.vanbaalenii_PYR-1 PQQG-FPPICTIWGLKNKIVSPE-AGRRLNSTLHPA-RQEWLPDCGHLLM
MAB_0139c|M.abscessus_ATCC_199 PGPD-FPPFAVIWGDSNLGLSPR-AGRALNRTLQPD-REEFLTRCGHLPM
Mflv_2367|M.gilvum_PYR-GCK HLTT-ELPLMVIWGDQDRIIPVD-HGFALDQHRPGC-RLEILDGVGHFPH
MAV_4567|M.avium_104 RLRE-ELPVMAIWGERDGIIPVD-HAYAAHEARTDA-RLEVLPDVGHFAQ
MUL_3358|M.ulcerans_Agy99 YLTQ-AIPVQIIWGSRDAVVPVR-HAEMAHAAMPGS-KLEVFEGSGHFPF
Mb1864c|M.bovis_AF2122/97 PATLGTKPTLLIWGMKDVAFRPKTIIPRLSATFPDH-VLVELPNAKHFIQ
Rv1833c|M.tuberculosis_H37Rv PATLGTKPTLLIWGMKDVAFRPKTIIPRLSATFPDH-VLVELPNAKHFIQ
MMAR_2710|M.marinum_M PAQLGTKPALLVWGMKDFAFRPEPMLARMRAVFADH-VLVELPEAKHFIQ
MLBr_02269|M.leprae_Br4923 PAYRSIAAPVLVIGFAEDVVTPPSLGREVADVLPNG-RYLQIPDAGHLGF
TH_1972|M.thermoresistible__bu ELAETSVPTHLVVCEKDRVLPNPRFVDHFHKNLREITRYTELDGVGHIPM
MSMEG_2913|M.smegmatis_MC2_155 AGID--IPVKILWGRDDLIMAPK-YGEWIRDQIPHA-EFHWIDDAGHVLQ
. : : . : *.
Mvan_1079|M.vanbaalenii_PYR-1 LERPDEVASIIDGFLQAPAETQA---------------------------
MAB_0139c|M.abscessus_ATCC_199 MESPEEVTAIITEFIARPPARRLG--------------DLATSPGSA---
Mflv_2367|M.gilvum_PYR-GCK VEKPDAVVDLLDDFIATTHAS----------------VRPADVPER----
MAV_4567|M.avium_104 VEAPMRVVELIEDFIATGER------------------RDATSPQPG---
MUL_3358|M.ulcerans_Agy99 HDDPARFIDIVLRFIDSTQPPEYDQAALRELLRTGGGERTVSDPADTRVA
Mb1864c|M.bovis_AF2122/97 EDAPDRIAAAIIERFG----------------------------------
Rv1833c|M.tuberculosis_H37Rv EDAPDRIAAAIIERFG----------------------------------
MMAR_2710|M.marinum_M EDAPDEIAAAIIARFG----------------------------------
MLBr_02269|M.leprae_Br4923 FERPEAVNAAALQFFAGVKGEWP---------------------------
TH_1972|M.thermoresistible__bu FEAPQRVADLIVDFLDDHTGK-----------------RRQASPGAVG--
MSMEG_2913|M.smegmatis_MC2_155 EDVPVQLLTHLTAPFAQSVNRSVG--------------------------
: * . :
Mvan_1079|M.vanbaalenii_PYR-1 -------------
MAB_0139c|M.abscessus_ATCC_199 -------------
Mflv_2367|M.gilvum_PYR-GCK -------------
MAV_4567|M.avium_104 -------------
MUL_3358|M.ulcerans_Agy99 VLSAMGSDERSAT
Mb1864c|M.bovis_AF2122/97 -------------
Rv1833c|M.tuberculosis_H37Rv -------------
MMAR_2710|M.marinum_M -------------
MLBr_02269|M.leprae_Br4923 -------------
TH_1972|M.thermoresistible__bu -------------
MSMEG_2913|M.smegmatis_MC2_155 -------------