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TSARFTFRGDTLAYSRTGTGPPILFLHNGGSAKEIWTRQVEVLRQRYEVICLDHLGYGESDMPERGYTID QHVERLSAFIEHLGHERISVVGNCMGSAMALLLADRRPELFDSLVLINPLSKNTARRGVLGWLLPLVSRF PTLSMAISRRVRIPQALTNIVITVQFGPRNWLRGIRAPRPGTAQAGKGWSVRGRLAALAEMFCDQTSLGA VDEIRPGPDFPPFAVIWGDSNLGLSPRAGRALNRTLQPDREEFLTRCGHLPMMESPEEVTAIITEFIARP PARRLGDLATSPGSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0139c | - | - | 100% (296) | alpha/beta fold family hydrolase |
| M. abscessus ATCC 19977 | MAB_3034 | - | 1e-16 | 24.91% (293) | hydrolase |
| M. abscessus ATCC 19977 | MAB_0349c | - | 1e-12 | 25.37% (272) | putative hydrolase, alpha/beta fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2734 | - | 7e-17 | 25.32% (316) | hydrolase |
| M. gilvum PYR-GCK | Mflv_2367 | - | 1e-18 | 27.30% (293) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv2715 | - | 7e-17 | 25.32% (316) | hydrolase |
| M. leprae Br4923 | MLBr_02269 | - | 1e-10 | 25.74% (272) | putative hydrolase |
| M. marinum M | MMAR_1997 | - | 4e-15 | 25.00% (300) | hydrolase |
| M. avium 104 | MAV_4567 | - | 2e-20 | 26.71% (292) | dihydrolipoyllysine-residue acetyltransferase component of |
| M. smegmatis MC2 155 | MSMEG_1897 | pcaD | 3e-13 | 34.69% (98) | 3-oxoadipate enol-lactonase |
| M. thermoresistible (build 8) | TH_2963 | - | 7e-15 | 27.80% (295) | PUTATIVE putative 3-oxoadipate enol-lactonase |
| M. ulcerans Agy99 | MUL_3358 | - | 2e-15 | 25.00% (300) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_1079 | - | 3e-53 | 39.78% (279) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0139c|M.abscessus_ATCC_199 MTSAR----------------FTFRGDTLAYSRTGTGP----PILFLHNG
Mvan_1079|M.vanbaalenii_PYR-1 MES------------------FDFRGMRIAYEHTGQGE----PVIMLHNG
Mb2734|M.bovis_AF2122/97 MTERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGP----AILLIHGI
Rv2715|M.tuberculosis_H37Rv MTERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGP----AILLIHGI
MMAR_1997|M.marinum_M MTERKRNLRPVREVTAPSLQFRTIHGYKRAFRIAGSGP----AILLIHGI
MUL_3358|M.ulcerans_Agy99 MTERKRNLRPVREVTAPSLQFRTIHGYKRAFRIAGSGP----AILLIHGI
Mflv_2367|M.gilvum_PYR-GCK MTD---------------LRYLDLHGDRCAYRDEGDGEE---TLLLLHGM
MAV_4567|M.avium_104 MSE---------------LKFLELHGDRVAFRDQGEGE----VLLLIHGM
MLBr_02269|M.leprae_Br4923 -------------------------MINLAYEDRGTGE----PVVFIAGR
TH_2963|M.thermoresistible__bu ------------------MPRFSRAGTTIDYTDTGAPAGRLEAPTILFGH
MSMEG_1897|M.smegmatis_MC2_155 ---------------------MSSVAVHHVVTGRSDGP----AVVFSNSL
. : .
MAB_0139c|M.abscessus_ATCC_199 GSAKEIWT--RQVEVLRQRYEVICLDHLGYGESDMPERGYTIDQHVERLS
Mvan_1079|M.vanbaalenii_PYR-1 GSSHAIWQ--DVANRLAGKYELFAFDLLGFGNSAKPGAGYTLDNYVAMLE
Mb2734|M.bovis_AF2122/97 GDNSTTWN--GVHAKLAQRFTVIAPDLLGHGQSDKPRADYSVAAYANGMR
Rv2715|M.tuberculosis_H37Rv GDNSTTWN--GVHAKLAQRFTVIAPDLLGHGQSDKPRADYSVAAYANGMR
MMAR_1997|M.marinum_M GDNSTTWT--GIHAKLAQRFTVIAPDLLGHGRSDKPRADYSIAAYANGMR
MUL_3358|M.ulcerans_Agy99 GDNSTTWT--GIHAKLAQRFTVIAPDLLGHGRSDKPRADYSIAAYANGMR
Mflv_2367|M.gilvum_PYR-GCK AGSSETWR--AVIPHLAKRYRVIAPDLLGHGSSAKPRGDYSLGAFAAWLR
MAV_4567|M.avium_104 AGSSETWR--SVIPPLAKKFRVIAPDLLGHGESAKPRTDYSLGAFAVWLR
MLBr_02269|M.leprae_Br4923 GGAGRTWQPHQVPAFLAAGYRVITFDNRGIGATEN-TEGFTTQTMVADTA
TH_2963|M.thermoresistible__bu GLLFSGWQFNLQIYALRRYYRCLAIDWRGQGASSGAARPYDMDTLTEDAA
MSMEG_1897|M.smegmatis_MC2_155 GSTHRMWD--PQLAAFEERFRVVRYDTRGHGQSPVPEGPYTIDDLADDVV
. * : : . * * * : : .
MAB_0139c|M.abscessus_ATCC_199 AFIEHLGHERISVVGNCMGSAMALLLADRRPELFDSLVLINPLSKNTARR
Mvan_1079|M.vanbaalenii_PYR-1 EFVSSRGLEKVAVVGNCMGSAIALAFTDRHRDQVKALVLCNPLTESTFLG
Mb2734|M.bovis_AF2122/97 DLLSVLDIERVTIVGHSLGGGVAMQFAYQFPQLVDRLILVS----AGGVT
Rv2715|M.tuberculosis_H37Rv DLLSVLDIERVTIVGHSLGGGVAMQFAYQFPQLVDRLILVS----AGGVT
MMAR_1997|M.marinum_M DLLSVLDIERVTIIGHSLGGGVAMQFAYQFPQLVDRLILVG----AGGVT
MUL_3358|M.ulcerans_Agy99 DLLSVLDIERVTIIGHSLGGGVAMQFAYQFPQLVDRLILVG----AGGVT
Mflv_2367|M.gilvum_PYR-GCK DLLDELGIRSVTVVGQSLGGGVAMQFVYQHPDYCRRLVLIS----SGGLG
MAV_4567|M.avium_104 DFLDELGVSRATVVGHSLGGGVAMQFVYQHPDYAQRLILIS----SGGLG
MLBr_02269|M.leprae_Br4923 VLIESLGAVPARIVGVSMGSFIAQELMVARPELVRAAVLMA---------
TH_2963|M.thermoresistible__bu HLVRSLGVAPAHYVGLSMGGFVGIRLAARHPELVRSLVLMN---------
MSMEG_1897|M.smegmatis_MC2_155 ALLDTLGIERAHVVGLSLGGMTAMRLSARNPQRVDRIALLC---------
:: . :* .:*. . : : *
MAB_0139c|M.abscessus_ATCC_199 GVLGWLLPLVSRFPTLSMAISR---RVRIPQALTNIVITVQFGPRNWLRG
Mvan_1079|M.vanbaalenii_PYR-1 GWLGPFLWLRERMPGINRQVYRLLGRLKLTNGIGSVATLFQLGPRG--RA
Mb2734|M.bovis_AF2122/97 KDVNIVFRLASLPMGSEAMALLRLPLVLPAVQIAGRIVGKAIGTTSLGHD
Rv2715|M.tuberculosis_H37Rv KDVNIVFRLASLPMGSEAMALLRLPLVLPAVQIAGRIVGKAIGTTSLGHD
MMAR_1997|M.marinum_M KDVNVVFRLASLPMGAEALALLRLPMVLPTVQLAGKVLGMALGSTALGQD
MUL_3358|M.ulcerans_Agy99 KDVNVVFRLASLPMGAEALALLRLPMVLPTVQLAGKVLGMALGSTALGQD
Mflv_2367|M.gilvum_PYR-GCK QDVGWTLRLLSAPG---SELLLPLIAPSPVVRAGDRVRAWFSARNIQSPR
MAV_4567|M.avium_104 PDVGWVLRLLSAPG---AELVLPVIAPTPVLSVGNKLRSWLRGAGIQSPR
MLBr_02269|M.leprae_Br4923 -TRGRLDRTRQFFHAAEAEFHDSGIQLPSGYNAKVRLLENLSRKTLNDDV
TH_2963|M.thermoresistible__bu TSAGPEDPAKADRYRTMARIYRFTGIGPLRRAVLPLMFGPAFLADPDSED
MSMEG_1897|M.smegmatis_MC2_155 --TATHLPPSSAWTERAAAVRTHGSAAVAESVVGRWFTPGFLAADPGRKA
MAB_0139c|M.abscessus_ATCC_199 IRAPRPGTAQAGKGWSVRGRLAALAEMFCDQTSLGAVDEIRPGPDFPPFA
Mvan_1079|M.vanbaalenii_PYR-1 LKLHR--NAELCGCYAATGQVESLLGVLDDLENYSVVDNLAPQQGFPPIC
Mb2734|M.bovis_AF2122/97 LPNVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQ
Rv2715|M.tuberculosis_H37Rv LPNVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQ
MMAR_1997|M.marinum_M LPNVLRILDDLPEPTASSAFTRTLRAVVDWRGQIVTMLDRCYLTQAIPVQ
MUL_3358|M.ulcerans_Agy99 LPNVLRILDDLPEPTASSAFTRTLRAVVDWRGQIVTMLDRCYLTQAIPVQ
Mflv_2367|M.gilvum_PYR-GCK GAEMWSAYASLSDAHTRHAFLRTLRSVVDYRGQAVSALNKLHLTTELPLM
MAV_4567|M.avium_104 GAELWNAYSSLSDGETRQSFLKTLRSVVDYRGQAVSALNRLRLREELPVM
MLBr_02269|M.leprae_Br4923 AVADWIAMFNMWPIKSTPG-LRCQTDVAPQNNRLPAYRSIA-----APVL
TH_2963|M.thermoresistible__bu VIDEWERRLRRYPRSSVRDAVLAVANRAGVEDELAAI--------DVPTL
MSMEG_1897|M.smegmatis_MC2_155 AYQQMIAATPAEGYAGCCEAIAALDLRADLAR------------ITAPTL
*
MAB_0139c|M.abscessus_ATCC_199 VIWGDSNLGLSPRAGRALNRTLQPDREEFLTRCGHLPMMESPEEVTAIIT
Mvan_1079|M.vanbaalenii_PYR-1 TIWGLKNKIVSPEAGRRLNSTLHPARQEWLPDCGHLLMLERPDEVASIID
Mb2734|M.bovis_AF2122/97 IIWGTKDVVLPVRHAHMAHAAMPGSQLEIFEGSGHFPFHDDPARFIDIVE
Rv2715|M.tuberculosis_H37Rv IIWGTKDVVLPVRHAHMAHAAMPGSQLEIFEGSGHFPFHDDPARFIDIVE
MMAR_1997|M.marinum_M IIWGSRDAVVPVRHAEMAHAAMPGSKLEVFEGSGHFPFHDDPARFIDIVL
MUL_3358|M.ulcerans_Agy99 IIWGSRDAVVPVRHAEMAHAAMPGSKLEVFEGSGHFPFHDDPARFIDIVL
Mflv_2367|M.gilvum_PYR-GCK VIWGDQDRIIPVDHGFALDQHRPGCRLEILDGVGHFPHVEKPDAVVDLLD
MAV_4567|M.avium_104 AIWGERDGIIPVDHAYAAHEARTDARLEVLPDVGHFAQVEAPMRVVELIE
MLBr_02269|M.leprae_Br4923 VIGFAEDVVTPPSLGREVADVLPNGRYLQIPDAGHLGFFERPEAVNAAAL
TH_2963|M.thermoresistible__bu VIGGAQDAATPPAHAQALAAGIRGARLEIIDDCGHSSPLERPDVVTELLR
MSMEG_1897|M.smegmatis_MC2_155 AIAGTDDPATPPDRLAEITAAVRGARLVQVTPGAHLANVEQADAITPTLL
* : . : . .* : . .
MAB_0139c|M.abscessus_ATCC_199 EFIARPPARRLGDLATSPGSA-----------------------------
Mvan_1079|M.vanbaalenii_PYR-1 GFLQAPAETQA---------------------------------------
Mb2734|M.bovis_AF2122/97 RFMDTTEPAEYDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNERSA
Rv2715|M.tuberculosis_H37Rv RFMDTTEPAEYDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNERSA
MMAR_1997|M.marinum_M RFIDSTQPPEYDQAALRELLRTGGGERTVSGPADTRVAVLSAMGSDERSA
MUL_3358|M.ulcerans_Agy99 RFIDSTQPPEYDQAALRELLRTGGGERTVSDPADTRVAVLSAMGSDERSA
Mflv_2367|M.gilvum_PYR-GCK DFIATTHASVRPADVPER--------------------------------
MAV_4567|M.avium_104 DFIATGER--RDATSPQPG-------------------------------
MLBr_02269|M.leprae_Br4923 QFFAGVKGEWP---------------------------------------
TH_2963|M.thermoresistible__bu GFLLEHT-------------------------------------------
MSMEG_1897|M.smegmatis_MC2_155 EHLGTEQS------------------------------------------
.:
MAB_0139c|M.abscessus_ATCC_199 -
Mvan_1079|M.vanbaalenii_PYR-1 -
Mb2734|M.bovis_AF2122/97 T
Rv2715|M.tuberculosis_H37Rv T
MMAR_1997|M.marinum_M T
MUL_3358|M.ulcerans_Agy99 T
Mflv_2367|M.gilvum_PYR-GCK -
MAV_4567|M.avium_104 -
MLBr_02269|M.leprae_Br4923 -
TH_2963|M.thermoresistible__bu -
MSMEG_1897|M.smegmatis_MC2_155 -