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M. thermoresistible (build 8) TH_1972 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 3824891 - 3825733
length: 281

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1972-100% (281)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_4292-5e-0724.83% (286) PUTATIVE putative epoxide hydrolase
M. thermoresistible (build 8)TH_4528-2e-0625.10% (239) PUTATIVE alpha/beta hydrolase fold

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3370-1e-10063.91% (266) hypothetical protein Mb3370
M. gilvum PYR-GCKMflv_4874-1e-8959.11% (269) alpha/beta hydrolase fold
M. tuberculosis H37RvRv3338-5e-7663.11% (206) hypothetical protein Rv3338
M. leprae Br4923MLBr_00685-7e-9357.55% (278) putative hydrolase
M. abscessus ATCC 19977MAB_3685-7e-6847.16% (282) hypothetical protein MAB_3685
M. marinum MMMAR_1187-5e-9663.77% (265) hypothetical protein MMAR_1187
M. avium 104MAV_4312-7e-9359.09% (264) hydrolase, alpha/beta fold family protein, putative
M. smegmatis MC2 155MSMEG_1655-1e-10565.11% (278) hydrolase, alpha/beta fold family protein, putative
M. ulcerans Agy99MUL_1440-4e-7961.64% (232) hypothetical protein MUL_1440
M. vanbaalenii PYR-1Mvan_1555-1e-12777.66% (282) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


TH_1972|M.thermoresistible__bu      ------------------------MSERAPIHLGSG----EPVLLLHPFM
Mvan_1555|M.vanbaalenii_PYR-1       ------------------------MNLREPIHLGSG----EPVLLLHPFM
MSMEG_1655|M.smegmatis_MC2_155      ------------------------MVERAPIHLGSRDGNTEPILLLHPFL
Mb3370|M.bovis_AF2122/97            --MPSPSTTGHHAACGTGGTGFSVGSMRSPIRVGSG----EPVLLLHPFL
Rv3338|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1187|M.marinum_M               ------------------------------------------MLLLHPFL
MUL_1440|M.ulcerans_Agy99           --------------------------------------------------
MAV_4312|M.avium_104                -------------------------------------------MLLHGFL
MLBr_00685|M.leprae_Br4923          MPACQHQRHRPVVACGTRGTTFRVGSMRQPIHLGSG----EPVLLLHPFM
Mflv_4874|M.gilvum_PYR-GCK          ------------------------MAPREPIHRGTG----EPIVLLHPFL
MAB_3685|M.abscessus_ATCC_1997      ---------------MLEAILSKPSNRRAPIEMGEG----EPVLLLHPFM
                                                                                      

TH_1972|M.thermoresistible__bu      MSQSVWKDVAPRIAG----------TGRYEVYAPTMPGHNGGV-KGRFF-
Mvan_1555|M.vanbaalenii_PYR-1       MSQNVWKDVAPQLAGVDVANPSAPATGRYEVLAPTMPGHNGGV-KGRFF-
MSMEG_1655|M.smegmatis_MC2_155      LSQSVWKYVAPQLAD----------TGRYEVFAPTMADHNGGP-RGPFL-
Mb3370|M.bovis_AF2122/97            MSQTVWEKVAQQLAD----------TGRFEVFAPTMAGHNGGPASGTRF-
Rv3338|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1187|M.marinum_M               LSQAVWEQVAQRLAD----------TGRYEVFAPTMASHNGGPRAGTWF-
MUL_1440|M.ulcerans_Agy99           -----------------------------------MASHNGRPRAGTWF-
MAV_4312|M.avium_104                MSQTVWDPVAPRLAD----------TGRYEVFAPTMAGHNGGPYAGTWL-
MLBr_00685|M.leprae_Br4923          MSQTVWEIVAPQLAN----------TERYEVFAPTMAAHHGGPSASSWM-
Mflv_4874|M.gilvum_PYR-GCK          CSQNVWRTVADQLAD----------TERFEVFAPTMVGHHGGPKSPTWL-
MAB_3685|M.abscessus_ATCC_1997      LSQSVWETVAEQLAD-----------AGYEVFAPTYPGHNGGGPMPKLPP
                                                                                      

TH_1972|M.thermoresistible__bu      ---LDTAELADDMERRLDELGWDTAHIVGNSLGGWVAFELERRGRARTLT
Mvan_1555|M.vanbaalenii_PYR-1       ---LDTAELADDMERRMDALGWDTAHVVGNSLGGWVAFELERRGRVRSLT
MSMEG_1655|M.smegmatis_MC2_155      ---LDVAHLADDIERRMDEVGWTTAHIVGNSLGGWVAFELERRGRARTLT
Mb3370|M.bovis_AF2122/97            ---LSSAVLADHVERQLDELGWETSHIVGNSLGGWVAFELERRGRARSVT
Rv3338|M.tuberculosis_H37Rv         ---MSSAVLADHVERQLDELGWETSHIVGNSLGGWVAFELERRGRARSVT
MMAR_1187|M.marinum_M               ---LSSAVLADHVERQMDELGWDSAHIVGNSLGGWVAFELERRGRARSVT
MUL_1440|M.ulcerans_Agy99           ---LSSAVLADHVERQMDELGWDSAHIVGNSLGGWVAFELERRGRARSVT
MAV_4312|M.avium_104                ---LSSSVLADHVERQLDRLGWDSAHLVGNSLGGWVAFELERRGRARSVT
MLBr_00685|M.leprae_Br4923          ---MSVSTLADHVEQQLDELGWDTAHLVGNSLGGWVVFELERRGRARSVT
Mflv_4874|M.gilvum_PYR-GCK          ---LHTEVLVDDIEHRMDQLGWDTAHIVGNSLGGWVAFELERRGRARTLT
MAB_3685|M.abscessus_ATCC_1997      FSQRSVDVYLDQIEQIMDQKGWETAHLVGNSLGGWIALGLALRGRARSVT
                                              *.:*: :*  ** ::*:********:.: *  ***.*::*

TH_1972|M.thermoresistible__bu      GIAPAGGWHRWSPAKYEIVGKFVLGFPVWAVAKLLGRRAARLPIARQLAF
Mvan_1555|M.vanbaalenii_PYR-1       AIAPAGGWHRWSLPKYEIVFKFVMGFPVWLTAKALGPRAARLPGARAAAS
MSMEG_1655|M.smegmatis_MC2_155      GIAPAGGWTRFTPAKYEIVAKFVGGLPIVLATKLLGQRVHRLPFTRHISY
Mb3370|M.bovis_AF2122/97            GIAPAGGWTRWSPVKFEVIAKFIAGAPILAVAHILGQRALRLPFSRLLAT
Rv3338|M.tuberculosis_H37Rv         GIAPAGGWTRWSPVKFEVIAKFIAGAPILAVAHILGQRALRLPFSRLLAT
MMAR_1187|M.marinum_M               GIAPAGGWTRWSPAKFEVIIKFVMGIPLLALAWLLGPRVMRLPFSRRLAT
MUL_1440|M.ulcerans_Agy99           GIAPAGGWTRWSPAKFEVIIKFVMGIPLLALAWLFGPRVMRLPFSRRLAT
MAV_4312|M.avium_104                GIGAAGGWTRWSPVKFEVIGKFIGGMPLLLLARLLGQRILQLPLSRRLAT
MLBr_00685|M.leprae_Br4923          GIAPAGGWTRWSLAKFEVIAKFVAGMPLVAVARGLGSRALSLPFSHRLAS
Mflv_4874|M.gilvum_PYR-GCK          AIAPAGGWPHHSLSKYETVLKFIMGGPALIAARLLGPRILNVPGARRLAT
MAB_3685|M.abscessus_ATCC_1997      AIAPAGGWTKYSPLKAEIVVKFAAMLPWLAFSRLLGRRAAGLPFAKFATA
                                    .*..**** : :  * * : **    *    :  :* *   :* ::  : 

TH_1972|M.thermoresistible__bu      VAVSAYPDGISDDDLVQIIDDVTHCAAYYQLLVKALLLPGLMELAETSVP
Mvan_1555|M.vanbaalenii_PYR-1       VPVSATPDGISDADMLDIIDDVTHCAAYYQLLVKALLLPGLMELADTRIP
MSMEG_1655|M.smegmatis_MC2_155      VAVAATADSLTDDDRRDLIDDLAHCPAYHKLLLKSLTTAGLMELPNSCTP
Mb3370|M.bovis_AF2122/97            LPISATPDGVSERELSGIIDDAAHCPAYFQLLVKALVLPGLQELEHTAVP
Rv3338|M.tuberculosis_H37Rv         LPISATPDGVSERELSGIIDDAAHCPAYFQLLVKALVLPGLQELEHTAVP
MMAR_1187|M.marinum_M               YAISASPDGVSDAELLGCIDDVAHCPAYLQLLVKALLLHGLRELAENAVP
MUL_1440|M.ulcerans_Agy99           YAISASPDGVSDAELLGCIDDVAHCPAYLQLLVKALLLRGLRELAENAVP
MAV_4312|M.avium_104                LPLSATPSGVSERQLSGVVEDAAHCPAYFQLLVKSLLQPGLLELAQTAVP
MLBr_00685|M.leprae_Br4923          LPLTGSPAGLSEHQLRNIVEDAGHCPAYFLLLIKTLLQPGLRELADITVP
Mflv_4874|M.gilvum_PYR-GCK          LPVSGPADGPSQSDLAALVEDATHCSAYLQLLVKTLRMPGLLELASLGAP
MAB_3685|M.abscessus_ATCC_1997      RMLCGETEALSLPDFHSIFEDITHCPAYFASLTSILPAPGLENLDTISVP
                                      : . . . :  :    .:*  **.**   * . *   ** :*     *

TH_1972|M.thermoresistible__bu      THLVVCEKDRVLPNPRFVDHFHKNLREITRYTELDGVGHIPMFEAPQRVA
Mvan_1555|M.vanbaalenii_PYR-1       THMVICEKDRVLPHPRFVNHFRKHLPESTRFTALDGVGHIPMFEAPGRIA
MSMEG_1655|M.smegmatis_MC2_155      THLVICEKDRVLPHPRFTRHFTRHLPANAEVTHLDGVGHVPMFEAPGRVT
Mb3370|M.bovis_AF2122/97            SHVVLCEQDRVVPPSRFSRHFTDSLPAGHRLTVLDGVGHVPMFEAPGRIT
Rv3338|M.tuberculosis_H37Rv         SHVVLCEQDRVVPPSRFSRHFTDSLPAGHRLTVLDGVGHVPMFEAPGRIT
MMAR_1187|M.marinum_M               AHLVICGKDRIIPAPRYSRHFTTHLPDDHRVTVLDNVGHVPMFEAPARVT
MUL_1440|M.ulcerans_Agy99           AHLVICGKDRIIPAPRYSRHFTTHLPDDHRVTVLDNVGHVPMFEAPARVT
MAV_4312|M.avium_104                VQLVLCEKDRVVPPSRFSRHFTDHLPPETRITRLDGVGHVPMFEAPERVT
MLBr_00685|M.leprae_Br4923          VLLVLCEKDRVLPPPKYSRHFTDHLPERTQVTKFDGMGHVPMFEAPEVIT
Mflv_4874|M.gilvum_PYR-GCK          TQLVLCEKDRVFPTPRGNRYFLTHLPDEARVVRLDGVGHIPMLEAPGAIT
MAB_3685|M.abscessus_ATCC_1997      AQLVLCEKDEIVPPGRFGKLIGEGLPGNARRITLAGMGHVPMLEAPGQVT
                                      :*:* :*.:.*  :    :   *    .   : .:**:**:***  ::

TH_1972|M.thermoresistible__bu      DLIVDFLDDHTGKRRQASPGAVG
Mvan_1555|M.vanbaalenii_PYR-1       DLIRDFLDEQIDGQRTTG-----
MSMEG_1655|M.smegmatis_MC2_155      ELITEFVDRHTERGRAAG-----
Mb3370|M.bovis_AF2122/97            ELITSFIEECCPHVRAS------
Rv3338|M.tuberculosis_H37Rv         ELITSFIEECCPHVRAS------
MMAR_1187|M.marinum_M               ALISGFIEECCPHLRSAEPPAS-
MUL_1440|M.ulcerans_Agy99           ALISGFIEECCPHLRSAEPPAS-
MAV_4312|M.avium_104                TVLTDFIDDCVARSQRQQPPAS-
MLBr_00685|M.leprae_Br4923          KLITNFINQCSKPAEAASPAS--
Mflv_4874|M.gilvum_PYR-GCK          ELIADFVDDHSTPSGKAIG----
MAB_3685|M.abscessus_ATCC_1997      EVITDLIDPLVSAKRSAASDAG-
                                     ::  :::