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MEVLMSLLRPEAVLSKVITGGGRWSVRKPRYGDPAFCLMLEGLCVLDADGLDPLELRQGDFLLLPQTPEF TLGAGGDVAPTFAGLDHSRHTRHGGESEPVTMRMLGGYFRFDAANAPLLVALLPPLILVRADQPGAQRLH RLVELITGEADADGACRDIILQRLVEVLLIEAMRVHTAADLGGAQRGLIAGLADPVLAPALMELHADVTH GWTVEQLARVASVSRAVFAQRFTRTMGMPPMQYLLEWRVALAKELLRTERPAIAQLAQRVGYQSATAFTT AFTRVAGCSPTEFARTSGYVGDTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1013 | - | - | 100% (304) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0946 | - | 4e-29 | 32.27% (251) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4276 | - | 2e-10 | 27.72% (184) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5242 | - | 1e-131 | 79.05% (296) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0767c | - | 7e-27 | 33.64% (220) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 2e-05 | 28.92% (83) | transcriptional regulatory protein |
| M. avium 104 | MAV_0221 | - | 8e-05 | 31.31% (99) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_4655 | - | 1e-08 | 35.80% (81) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 2e-10 | 31.48% (162) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1013|M.vanbaalenii_PYR-1 ------------MEVLMSLLRPEAVLSKVITGGGRWSVRKPRYGDPAFCL
Mflv_5242|M.gilvum_PYR-GCK ------------MDVLMSLLRPQAVLSKVITGAGSWGVRKPRYGDPAFCL
MMAR_2855|M.marinum_M MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVAT
TH_3120|M.thermoresistible__bu -VAALVLDGLAIFEFGVICEVFGVDRTDDGVPPVDFTVCGPRAG-QPVRT
MAB_0767c|M.abscessus_ATCC_199 ----MIHNPDYFADQPKSLSWPTGSPSIDAFSGILSAIGLRGESALRCSA
MSMEG_4655|M.smegmatis_MC2_155 -----------------------MQTERELLTEICERIDRHARGDMHTRI
MAV_0221|M.avium_104 --------------------------MYRPSPPLAEHIEYFGYWRGDEAL
:
Mvan_1013|M.vanbaalenii_PYR-1 MLEGLCVLDADGLDPLELRQGDFLLLP----QTPEFTLGAGGDVAPTFAG
Mflv_5242|M.gilvum_PYR-GCK MLEGSCVLDADGLDSIALSQGDFLLLP----ETPEFTLSAGPEATPSFSA
MMAR_2855|M.marinum_M GIG-LEFMTTRLPDPSAP--VDTVVLPGGGGVDAARDNVALMDWVKAAAG
TH_3120|M.thermoresistible__bu SFG-ATLTPDSGLDGLAG--ADLVAIP---AIRQDDYLPEALDAVRAAAD
MAB_0767c|M.abscessus_ATCC_199 ELPFDVSVPANERVLHIAETAGLRVYVD----GNPVCVLAAGDMVLMARG
MSMEG_4655|M.smegmatis_MC2_155 DGLLLSKAAGSSRPDYTVTEPLLVVMAR---GGKRIMVGDEVYEYRTGEM
MAV_0221|M.avium_104 GVHTSRALPRGAVTAIID-------------VGGRTDLGFYASDARTPLT
Mvan_1013|M.vanbaalenii_PYR-1 LDHSRHTRHGGESEPVTMRMLGGYFRFDAANAPLLVALLPPLILVRADQP
Mflv_5242|M.gilvum_PYR-GCK LDHSPHTRHGDASAPVTMRMLGGYFRFDPANAALLVALLPPVIHVRGGDP
MMAR_2855|M.marinum_M TARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPI
TH_3120|M.thermoresistible__bu AGAIILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELARRYPTARVDRNVL
MAB_0767c|M.abscessus_ATCC_199 TAHRLSGAQPHGEPAGTLHWVSGRFTAERKAADPLLSVLPPAIIIQAARP
MSMEG_4655|M.smegmatis_MC2_155 LIVTASLPVTGHYLETDQPSLGMGLELRPAALAELALRAPARPALRTGSA
MAV_0221|M.avium_104 VPPAFAAGAGATAYVVRVAPAHTVMTIHFRPAGALAFLGSPLSDLEDALV
. :
Mvan_1013|M.vanbaalenii_PYR-1 GAQRLHRLVELITGEADADGACRDIILQRLVEVLLIEAMRVHTAADLGGA
Mflv_5242|M.gilvum_PYR-GCK DAPRLTRLVELIAEEADADGACRDAILQRLVEVLLIEAARVQSAPDLAGP
MMAR_2855|M.marinum_M FIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPGG
TH_3120|M.thermoresistible__bu YVDDG-DLITSAGTAAGIDACLHLVRRELGSEVTNTIARHMVVPPQRDGG
MAB_0767c|M.abscessus_ATCC_199 GHEWLPLSLQLILAEILTPSPGSWVMISRILDLLFIHAVREWSSS--SHA
MSMEG_4655|M.smegmatis_MC2_155 GSAIAVGNADAEMLDAAAR-LLRLLDRPDDAPVLAPLVEQEILWRLLTGP
MAV_0221|M.avium_104 GLEDLWGRDAALLREQLIDAGSPPRRVALLQAFLVRRMRRNAVWP-----
.
Mvan_1013|M.vanbaalenii_PYR-1 QRGLIAGL-----ADPVLAPALMELHADVTHGWTVEQLARVASVSRAVFA
Mflv_5242|M.gilvum_PYR-GCK HRGLITGL-----ADPVLAPALRALHADIAHGWTVEGLARTASVSRAVFA
MMAR_2855|M.marinum_M QTQFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPRHFT
TH_3120|M.thermoresistible__bu QRQFIDQP-IPVRHSEGFAPHLDWILSNLDKTHTVASLARRANMSPRTFA
MAB_0767c|M.abscessus_ATCC_199 EPGWLTAA-----MDPRLAPVLTAIHNNLEHPWSIAELAQHARQSRSAFT
MSMEG_4655|M.smegmatis_MC2_155 HGDTVRQIALADSALTYINRAITWMRDNYASPVRIEDLARMAGMSTSVFH
MAV_0221|M.avium_104 --------------PARLAPVLRG--ADLDPSMRVSKAQELSGLSRKRFA
: : : . : * *
Mvan_1013|M.vanbaalenii_PYR-1 QRFTRTMGMPPMQYLLEWRVALAKELLRTERPAIAQLAQRVGYQSATAFT
Mflv_5242|M.gilvum_PYR-GCK QKFTRAMGLTPMQYLLEWRVAVAKDLMRSERLSIAQLAQRVGYQSATAFT
MMAR_2855|M.marinum_M RVFTGEVGEAPRQYVERVRTEAARRQLEETEDTVVAIAARCGFGTAETMR
TH_3120|M.thermoresistible__bu RRFVEETGRTPMQWVTDQRVLYARRLLEETDLDIHRIAARCGFGSTTLLR
MAB_0767c|M.abscessus_ATCC_199 QRFTELLGQPPAAYIGERRLDRAAHLLRSTTDPVRQIGRAVGYTSDAAFS
MSMEG_4655|M.smegmatis_MC2_155 RHFRAVTAMSPLQFQKRIRLQQARSLLVSQPGDVAAVAHLVGYDSASQFT
MAV_0221|M.avium_104 ALFRCEVGLSPKAYLRVLRLQAALRALDTP-ARGATIAADLGYFDQAHFV
* . .* : * * : :. *: :
Mvan_1013|M.vanbaalenii_PYR-1 TAFTRVAGCSPTEFARTSGYVGDTG-----------
Mflv_5242|M.gilvum_PYR-GCK TAFTRVAGAPPTEFARTLAPGGV-------------
MMAR_2855|M.marinum_M RNFIRRVGISPDQYRKAFA-----------------
TH_3120|M.thermoresistible__bu HHFRRVIGVTPSDYRRRFACGSTTSGSTESGAEVTD
MAB_0767c|M.abscessus_ATCC_199 RAFQRRFGEPPLRWRTHHRSG---------------
MSMEG_4655|M.smegmatis_MC2_155 REYRRMFGAPPGQDAARLRAAHAPEPALLP------
MAV_0221|M.avium_104 REFRAFTGATPTQYARRRSSMPGHVELAR-------
: * .*