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YRPSPPLAEHIEYFGYWRGDEALGVHTSRALPRGAVTAIIDVGGRTDLGFYASDARTPLTVPPAFAAGAG ATAYVVRVAPAHTVMTIHFRPAGALAFLGSPLSDLEDALVGLEDLWGRDAALLREQLIDAGSPPRRVALL QAFLVRRMRRNAVWPPARLAPVLRGADLDPSMRVSKAQELSGLSRKRFAALFRCEVGLSPKAYLRVLRLQ AALRALDTPARGATIAADLGYFDQAHFVREFRAFTGATPTQYARRRSSMPGHVELAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0221 | - | - | 100% (268) | transcriptional regulator, AraC family protein |
| M. avium 104 | MAV_2711 | - | 1e-16 | 30.95% (252) | transcriptional regulator, AraC family protein |
| M. avium 104 | MAV_0193 | - | 1e-05 | 26.67% (150) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 4e-05 | 26.53% (147) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2241 | - | 9e-13 | 30.00% (210) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv3833 | - | 6e-05 | 26.52% (132) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3701c | - | 1e-17 | 33.33% (198) | AraC family transcriptional regulator |
| M. marinum M | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5025 | - | 2e-12 | 28.24% (262) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_2588 | - | 1e-19 | 31.15% (260) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4454 | - | 1e-09 | 28.18% (220) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2241|M.gilvum_PYR-GCK ------------MAAWKNTTAGAPLRGVVGRPAGASAFDLRRWAADGRTS
Mvan_4454|M.vanbaalenii_PYR-1 ------------MGAWKNATAGEPLRGVVGRPASSSVFDLRRWAADGRTG
MSMEG_5025|M.smegmatis_MC2_155 ------------MAAWKN----APERGVVGRPGSASAFDLTRWAPSPEAG
Mb3863|M.bovis_AF2122/97 ------------------------MSENSHHRLATTSLTLP---PGARIE
Rv3833|M.tuberculosis_H37Rv ------------------------MSENSHHRLATTSLTLP---PGARIE
MAV_0221|M.avium_104 --------------MYRPSPPLAEHIEYFGYWRGDEALGVH---TSRALP
TH_2588|M.thermoresistible__bu -----------VRDPARIEIGGHPAAPLRPFVTGYTGFDLRGFEPGVHVG
MAB_3701c|M.abscessus_ATCC_199 MRSPARYEGRTTADASWRAVSAAADVTLSGIAHGYTELRERAHRPVERSE
. : .
Mflv_2241|M.gilvum_PYR-GCK R-YVEHYWSVNWDLRGNDPFDSTVITFPAMHITHEWGQDAVRHGFSLP-N
Mvan_4454|M.vanbaalenii_PYR-1 R-YVEHFWSVAWDLRGRDPFDTSVITFPAMHITREWGEDGARHGFPLP-N
MSMEG_5025|M.smegmatis_MC2_155 R-FVEHYWSVRWDRREAGPHESTVITFPAVHLTREWGDDIARHGHPLP-N
Mb3863|M.bovis_AF2122/97 R-HRHPSHQIVYPSAGAVSVTTHAGTWITPVNRAIWIPAGCWHQHKFHGH
Rv3833|M.tuberculosis_H37Rv R-HRHPSHQIVYPSAGAVSVTTHAGTWITPVNRAIWIPAGCWHQHKFHGH
MAV_0221|M.avium_104 R-GAVTAIIDVGGRTDLGFYASDARTPLTVPPAFAAGAGATAYVVRVAPA
TH_2588|M.thermoresistible__bu MPSHTLTAVLTFGEPLEIDVPSGLSGTSGRYPSMASGLLAQSISIRHRGA
MAB_3701c|M.abscessus_ATCC_199 VAGVAPVLVVELDAP-LLVADVADHASPRIWQAFVAGVSQGPSSTVHSGA
Mflv_2241|M.gilvum_PYR-GCK TLVHGVVEQVFRTTISEKGCVVGARFRPGGFTARFGGDASVRTGCVEPIG
Mvan_4454|M.vanbaalenii_PYR-1 TLVHGVVEQVFRTTISERGWVVGARFRPGGFTARFGGDASTMTGRIQPVD
MSMEG_5025|M.smegmatis_MC2_155 TLLHGVVTQVFRTTISSRGVVVGARFHPGGFTARFGRDAGELTDRVVPVD
Mb3863|M.bovis_AF2122/97 TQFHGVALDPQR----YRGGPATPTVLAVNPLMRELIIACSQADRTDTDE
Rv3833|M.tuberculosis_H37Rv TQFHGVALDPQR----YRGGPATPTVLAVNPLMRELVIACSQADRTDTDE
MAV_0221|M.avium_104 HTVMTIHFRPAGALAFLGSPLSDLEDALVGLEDLWGRDAALLREQLIDAG
TH_2588|M.thermoresistible__bu QRGVKLSFTPLGARMVFGMPAGALANSVVPLSDVLADLWPELEDRLGAAA
MAB_3701c|M.abscessus_ATCC_199 QHCIEVRLTPLGLHRVSGLAMDAVSNRVVSLEELFGKKARYLPERLAAEP
:
Mflv_2241|M.gilvum_PYR-GCK DL---FGAAVALPDDVEDAAAELDTLIGG-GGPPDAVFDALSALVDRIRD
Mvan_4454|M.vanbaalenii_PYR-1 DLSDVFGGPVLVPDDVDAAAAEFDRLIAH-GAEPDDTYRALAAVVDRIRD
MSMEG_5025|M.smegmatis_MC2_155 DD--LFGGPIDLGCDVSVVRSGFDAVIGDYSGDPDPVYARLMPLLERMRE
Mb3863|M.bovis_AF2122/97 HH-----RMLAVLQDQLPTTSIREPLWVP--SPTDRRLRHACALIADNLT
Rv3833|M.tuberculosis_H37Rv HH-----RMLAVLQDQLPTTSIREPLWVP--SPTDRRLRHACALIADNLT
MAV_0221|M.avium_104 SP----PRRVALLQAFLVRRMRRNAVWPP---------ARLAPVLRGADL
TH_2588|M.thermoresistible__bu TWP----HRFRVLDDVLARAVARTMCAGM-----FDVRPEVAAAWQRLVD
MAB_3701c|M.abscessus_ATCC_199 NWV----RRFDLLDSVFMRAAAEGPEADA----------EVEFAWHRLNR
. :
Mflv_2241|M.gilvum_PYR-GCK DSGVHRVEQVMDLSPWSVRTTQRVFRRYVGVPVKWVLCRYRLQNAALEIE
Mvan_4454|M.vanbaalenii_PYR-1 DSGIHRVEQVMSHSPWSVRTTQRVFRRYVGVPVKWVLCRYRLQNAALEIE
MSMEG_5025|M.smegmatis_MC2_155 DPTLHRVEQVMEHSPWSVRTTQRVFRRYVGVPVKWVLCRYRLQQAALEIE
Mb3863|M.bovis_AF2122/97 QP--LTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLA
Rv3833|M.tuberculosis_H37Rv QP--LTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLA
MAV_0221|M.avium_104 DPS-MRVSKAQELSGLSRKRFAALFRCEVGLSPKAYLRVLRLQAALRALD
TH_2588|M.thermoresistible__bu SRGQVRVGDLAHDLGCSRRHLTARFREEFGLTPKTLARILRLEQAVGLVA
MAB_3701c|M.abscessus_ATCC_199 TGGTAGIGEILNEIGWSRARLAQRFRSQVGLTPKAAARVLRFNRAMTLLN
: . * * .*:. *:: * :
Mflv_2241|M.gilvum_PYR-GCK TDPGVDFADLAVRLGWYDQAHFINDFRSMLGSTPGEYAAT----------
Mvan_4454|M.vanbaalenii_PYR-1 TDPAVDFADLAVRLGWYDQAHFINDFRAMLGSTPGEYAAT----------
MSMEG_5025|M.smegmatis_MC2_155 STGSVDFADLAVRLGWYDQAHFINDFRGMLGCTPGEYAMR----------
Mb3863|M.bovis_AF2122/97 ER--HDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKP----------
Rv3833|M.tuberculosis_H37Rv ER--HDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKP----------
MAV_0221|M.avium_104 TP--ARGATIAADLGYFDQAHFVREFRAFTGATPTQYARR----------
TH_2588|M.thermoresistible__bu AAGAPAWAEVSAAAGYADQAHLVRDWRSFTGRTPSSWFDG----------
MAB_3701c|M.abscessus_ATCC_199 QPGHRSLSSIALACGYFDQAHFNRDFRVLAGCSPRQWAALRHEDLMGYRI
: :: *: : : :* * :* .
Mflv_2241|M.gilvum_PYR-GCK --------YGQGR-----------
Mvan_4454|M.vanbaalenii_PYR-1 --------HGRRP-----------
MSMEG_5025|M.smegmatis_MC2_155 --------FGQKGGGS--------
Mb3863|M.bovis_AF2122/97 --------MAATRLTRLRRARDRR
Rv3833|M.tuberculosis_H37Rv --------MAATRLTRLRRARDRR
MAV_0221|M.avium_104 --------RSSMPGHVELAR----
TH_2588|M.thermoresistible__bu --------DVLVDGRPHG------
MAB_3701c|M.abscessus_ATCC_199 PADGEHLYKTGVDGGPSVGTVL--