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M. vanbaalenii PYR-1 Mvan_0983 (ubiE)

annotation: ubiquinone/menaquinone biosynthesis methyltransferase
coordinates: 1012128 - 1012814
length: 228

VNRASLEKDPHEVASMFDGVARRYDLTNTVLSLGQDRFWRRATREALQLSPSDKVLDLAAGTAVSTVELA
GSGAWCVAADFSVGMLAAGAARDVPKVAGDATRLPFADGVFDAVTISFGLRNVVDHSAGLREMARVTRPG
GRLVVCEFSTPTNKLFATVYKEYLMRALPAMASAVSSNPDAYVYLAESIRAWPDQAELAARIEAAGWSDV
RWRNLTGGIVALHAATKA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_0983ubiE-100% (228)ubiquinone/menaquinone biosynthesis methyltransferase
M. vanbaalenii PYR-1Mvan_4690-4e-1428.16% (174) methyltransferase type 11
M. vanbaalenii PYR-1Mvan_1928-5e-1236.29% (124) methyltransferase type 11

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0573ubiE1e-10582.38% (227) ubiquinone/menaquinone biosynthesis methyltransferase
M. gilvum PYR-GCKMflv_5258ubiE1e-11993.83% (227) ubiquinone/menaquinone biosynthesis methyltransferase
M. tuberculosis H37RvRv0558ubiE1e-10582.38% (227) ubiquinone/menaquinone biosynthesis methyltransferase
M. leprae Br4923MLBr_02273ubiE1e-9976.65% (227) ubiquinone/menaquinone biosynthesis methyltransferase
M. abscessus ATCC 19977MAB_3930c-1e-10582.30% (226) ubiquinone/menaquinone biosynthesis methlytransferase UbiE
M. marinum MMMAR_0907ubiE1e-10684.58% (227) ubiquinone/menaquinone methlytransferase, MenH
M. avium 104MAV_4584ubiE1e-10685.33% (225) ubiquinone/menaquinone biosynthesis methyltransferase
M. smegmatis MC2 155MSMEG_1115ubiE1e-11387.67% (227) ubiquinone/menaquinone biosynthesis methyltransferase
M. thermoresistible (build 8)TH_3050-5e-1230.81% (172) PUTATIVE Methyltransferase type 12
M. ulcerans Agy99MUL_0660ubiE1e-10684.14% (227) ubiquinone/menaquinone biosynthesis methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_0983|M.vanbaalenii_PYR-1       -----------------MNRASLEKDPHEVASMFDGVARRYDLTNTVLSL
Mflv_5258|M.gilvum_PYR-GCK          -----------------MNRASLEKNPHEVASMFDGVARRYDLTNTVLSL
MSMEG_1115|M.smegmatis_MC2_155      -----------------MSRASLEKNPHDVASMFDAVAKRYDLTNTVLSL
MAB_3930c|M.abscessus_ATCC_199      -----------------MNRATLEKDPHEVASMFDAVARRYDITNTVLSF
Mb0573|M.bovis_AF2122/97            -----------------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSL
Rv0558|M.tuberculosis_H37Rv         -----------------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSL
MMAR_0907|M.marinum_M               -----------------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSL
MUL_0660|M.ulcerans_Agy99           -----------------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSL
MAV_4584|M.avium_104                MQRWRRRGIPAPGSVKRVSRAELDKNPRDVASMFDGVARRYDLTNTVLSL
MLBr_02273|M.leprae_Br4923          ---------MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSL
TH_3050|M.thermoresistible__bu      -----------------VTGRRRHLDRAAVPAAFDAGAASYDRLVAANPG
                                                     :.    . :   * : **  *  **   :. . 

Mvan_0983|M.vanbaalenii_PYR-1       GQDRFWRRATREALQLSPSD----KVLDLAAGTAVSTVELAGSG--AWCV
Mflv_5258|M.gilvum_PYR-GCK          GQDRFWRRATREALQLSPAD----KVLDLAAGTAVSTVELASSG--AWCV
MSMEG_1115|M.smegmatis_MC2_155      GQDRFWRRETKSALRIGPAD----KVLDLAAGTAVSTVELAKSG--AWCV
MAB_3930c|M.abscessus_ATCC_199      GRDRFWRRATREALRLKPGD----KVLDIAAGTAVSTAELTQSG--AWCV
Mb0573|M.bovis_AF2122/97            GQDRYWRRATRSALRIGPGQ----KVLDLAAGTAVSTVELTKSG--AWCV
Rv0558|M.tuberculosis_H37Rv         GQDRYWRRATRSALRIGPGQ----KVLDLAAGTAVSTVELTKSG--AWCV
MMAR_0907|M.marinum_M               GQDRYWRRATRSALRIGPGD----KVLDLAAGTAVSTVELAKSG--AWCV
MUL_0660|M.ulcerans_Agy99           GQDRYWRRATRSALRIGPGD----KVLDLAAGTAVSSVELAKSG--AWCV
MAV_4584|M.avium_104                GQDRYWRKATRSALGIGPGQ----KVLDLAAGTAVSTVELNKSG--AWCV
MLBr_02273|M.leprae_Br4923          GQDRYWRRATRSALRIGPGQ----KVLDLAAGTAVSTAELSKSG--AWCV
TH_3050|M.thermoresistible__bu      YHEHLRLSAHRMGLPGCAARXRGLRILDAGCGTGASTAALLTYAPDAEIV
                                     :::      : .*   ..     ::** ..**..*:. *   .  *  *

Mvan_0983|M.vanbaalenii_PYR-1       AADFSVGMLAAGAAR----DVPKVAGDATRLPFA--DGVFDAVTISFGLR
Mflv_5258|M.gilvum_PYR-GCK          AADFSVGMLAAGASR----RVPKVAGDATRLPFD--DGVFDAVTISFGLR
MSMEG_1115|M.smegmatis_MC2_155      AADFSVGMLAAGASR----QVPKVAGDATRLPFA--DEVFDAVTISFGLR
MAB_3930c|M.abscessus_ATCC_199      AADFSVGMLKAGARR----DVPKVAGDATRLPFA--DHSFDAVTISFGLR
Mb0573|M.bovis_AF2122/97            AADFSVGMLAAGAAR----KVPKVAGDATRLPFG--DDVFDAVTISFGLR
Rv0558|M.tuberculosis_H37Rv         AADFSVGMLAAGAAR----KVPKVAGDATRLPFG--DDVFDAVTISFGLR
MMAR_0907|M.marinum_M               AADFSVGMLAAGHER----KVCKVAGDATRLPFA--DDVFDAVTISFGLR
MUL_0660|M.ulcerans_Agy99           AADFSVGMLAAGHER----RVCKVAGDATRLPFA--DDVFDAVTISFGLR
MAV_4584|M.avium_104                AADFSVGMLAAGAAR----RVPKVAGDATRLPFA--DDVFDAVTISFGLR
MLBr_02273|M.leprae_Br4923          AADFSVRMLATGGAR----KVPKVAADATQLPFS--DGVFDAVTISFGLR
TH_3050|M.thermoresistible__bu      AVDASAGMLAAAAAKPWPATVRFVHSRVEDLAGAGVGGPFDAVFAAYLLR
                                    *.* *. ** :.  :     *  * . .  *.    .  ****  :: **

Mvan_0983|M.vanbaalenii_PYR-1       NVVDHSAGLREMARVTRPGGRLVVCEFSTPTNKLFATVYKEYLMRALPAM
Mflv_5258|M.gilvum_PYR-GCK          NVVDFSAGLREMARVTRPGGRLVVCEFSTPTNGLFSTVYKEYLMKALPAM
MSMEG_1115|M.smegmatis_MC2_155      NVVDHKAGLREMARVTKPGGRLVVCEFSTPTNRLFSTVYKEYLMKALPAM
MAB_3930c|M.abscessus_ATCC_199      NVVDHVEGLREMARVTKPGGRLAVCEFSTPVNRPFRTLYMEYLMKTLPEV
Mb0573|M.bovis_AF2122/97            NVANQQAALREMARVTRPGGRLLVCEFSTPTNALFATAYKEYLMRALPRV
Rv0558|M.tuberculosis_H37Rv         NVANQQAALREMARVTRPGGRLLVCEFSTPTNALFATAYKEYLMRALPRV
MMAR_0907|M.marinum_M               NVVDFSAALREMARVTRPGGRLVVCEFSTPVSALFATVYKEYLMRALPRV
MUL_0660|M.ulcerans_Agy99           NVVDFSAALREMARVTRPGGRLVVCEFSTPVSALFATVYKEYLMRALPRV
MAV_4584|M.avium_104                NVVDTQAALREMARVTRPGGRLVVCEFSTPSNALFATVYKEYLMRALPRV
MLBr_02273|M.leprae_Br4923          NIADYQAALREMARVTRPGGQLVVCEFSTPTNALVANVYTEYLMRALPQV
TH_3050|M.thermoresistible__bu      NLPDPDTQLTAFRDLLRPGGILAVHEYSVRDSAVATAVWNVVCGAVVIPL
                                    *: :    *  :  : :*** * * *:*.  .      :      .:  :

Mvan_0983|M.vanbaalenii_PYR-1       ASAVSSNPDAYVYLAESIRAWPDQAELAARIEAAGWSDVRWRNLTG---G
Mflv_5258|M.gilvum_PYR-GCK          ATAVSSNPDAYVYLAESIRAWPDQRALARRIEAAGWSDVRWRNLTG---G
MSMEG_1115|M.smegmatis_MC2_155      ATAVSSNPEAYVYLAESIRAWPTQAELARQIGEAGWSDVRWRNLTG---G
MAB_3930c|M.abscessus_ATCC_199      ARAVSSNPDAYVYLAESIRAWPDQEALAHQIASAGWSNVRWRNLTG---G
Mb0573|M.bovis_AF2122/97            ARAVSSNPEAYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTG---G
Rv0558|M.tuberculosis_H37Rv         ARAVSSNPEAYEYLAESIRAWPDQAVLAHQISRAGWSGVRWRNLTG---G
MMAR_0907|M.marinum_M               ARAVSSNPEAYVYLAESIRAWPDQAALAQQMSRAGWSAVRWRNLTG---G
MUL_0660|M.ulcerans_Agy99           ARAVSSNPEAYVYLAESIRAWPDQAALAQQMSRAGWSAVRWRNLTG---G
MAV_4584|M.avium_104                ARAVSSNPDAYVYLAESIRAWPDQAALADQIAGAGWAGVRWRNLTG---G
MLBr_02273|M.leprae_Br4923          ARLVSSNPDAYIYLAESIRAWPDQVTLACQLSRTGWASPRWRNLTG---G
TH_3050|M.thermoresistible__bu      GRLRTGDAALYRYLRRSVNTFDGAERFRNRLRACGFTDVRSATMPGWQRD
                                    .   :.:.  * ** .*:.::     :  ::   *::  *  .:.*   .

Mvan_0983|M.vanbaalenii_PYR-1       IVALHAATKA------
Mflv_5258|M.gilvum_PYR-GCK          IVALHAATKP------
MSMEG_1115|M.smegmatis_MC2_155      IVALHAATKPA-----
MAB_3930c|M.abscessus_ATCC_199      IVALHIATL-------
Mb0573|M.bovis_AF2122/97            IVALHAGYKPGKQTPQ
Rv0558|M.tuberculosis_H37Rv         IVALHAGYKPGKQTPQ
MMAR_0907|M.marinum_M               IVALHAGYKP---QPV
MUL_0660|M.ulcerans_Agy99           IVALHAGYKP---QPV
MAV_4584|M.avium_104                IVALHAAHRP----PR
MLBr_02273|M.leprae_Br4923          IVALHAADKP----VR
TH_3050|M.thermoresistible__bu      IVHTFLARRPG-----
                                    **  . .