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MSAPTKSPKKRVHPVDEVLPLPKLATYGFQHVVAFYAGAVLVPILIANAIGLSGEELVMLITADLFTCGI ASIIQAVGFKNIGVRLPLLQGVTFAGVAPIIAIGLAHGGGTESLLYVYGAVIVAGVFTFLIAPMFVRLLK FFPPVVTGTLITIIGLCLVPIGALDAVTNPATHEPDPTNLRWVLYALGTIAVIVAIQRLFRGFMSTIAVL LGLVAGCTVAFTLGDMNFDRVAEASMFGFTPPFAFGMPRFDIVAIITMIIVMMIIAVESTGSTIATGEIV GKRVRPSDIGNVLRADGVATTIGGIFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIMILLGFLPKVAA IVASIPNPVLGGAALTLFATVAVVGIQTLGKVDFTDHRNVIIVTTSLALALLVTSYPDISSQLPAGLDIL FGSGISTGAITAIVLNIVFFHIVKKGPRVAGSGSITLDEVNAMTRERFTEVFGHVVQGVSWAADRAFDQR PFADTAALREAFQDAVLTGNAEQQQELLDAFHDLGAEDETGQVLAVDHVALSNLDEEDHQDVVTLAAAYR EHFGFPLIICARETERFDRVLRNGWSRMDNSPATEKAYALIEVAKIANYRFTDLVADANPIAAARFGRLN ELS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5275 | - | - | 100% (633) | uracil-xanthine permease |
| M. vanbaalenii PYR-1 | Mvan_0717 | - | 6e-34 | 26.22% (431) | uracil-xanthine permease |
| M. vanbaalenii PYR-1 | Mvan_5693 | - | 2e-08 | 22.93% (410) | sulphate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0188 | - | 4e-37 | 27.83% (442) | uracil-xanthine permease |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2932c | - | 0.0 | 63.84% (661) | xanthine/uracil permease |
| M. marinum M | MMAR_4949 | - | 0.0 | 80.85% (632) | xanthine/uracil permease |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1293 | - | 0.0 | 80.57% (633) | xanthine/uracil permeases family protein |
| M. thermoresistible (build 8) | TH_2104 | - | 6e-06 | 23.00% (400) | sulfate permease |
| M. ulcerans Agy99 | MUL_0456 | - | 7e-06 | 28.31% (166) | putative OHCU decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4949|M.marinum_M MSAPPTSPVR------RVHPVDEVLPIPKLATYGFQHVVAFYAGAVVVPI
MSMEG_1293|M.smegmatis_MC2_155 MVAPLTLQSKK-----RVHPVDEVPPVGKLATYGFQHVVAFYAGAVLVPI
Mvan_5275|M.vanbaalenii_PYR-1 MSAPTKSPKK------RVHPVDEVLPLPKLATYGFQHVVAFYAGAVLVPI
MAB_2932c|M.abscessus_ATCC_199 MSADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPL
Mflv_0188|M.gilvum_PYR-GCK MTLTWKRVDSTTDP-DFVVAPDERLSWPSTLGLGAQHVVAMFGATFLVPV
MUL_0456|M.ulcerans_Agy99 ------------------------MTKPALGLDGFNRLTDRQRMHLLFGV
TH_2104|M.thermoresistible__bu ----------------VIATAKENLIRLLPSRRDYAELPRSWRRDILAGI
. .: .: :
MMAR_4949|M.marinum_M IIANAIDLPHQDLVKLITADLFTCGVASIIQSVGFWKIGVRLPLLQGVAF
MSMEG_1293|M.smegmatis_MC2_155 LIATAIDLPTQDLVKLITADLFTCGIASIIQAVGFWKVGVRLPLLQGVTF
Mvan_5275|M.vanbaalenii_PYR-1 LIANAIGLSGEELVMLITADLFTCGIASIIQAVGFKNIGVRLPLLQGVTF
MAB_2932c|M.abscessus_ATCC_199 LIARAIDLDAEALTMLITADLFTCGVASILQAVGFWKIGVRLPLLQGVTF
Mflv_0188|M.gilvum_PYR-GCK LTG-----------FPPATTLLFSGVGTILFLL---ITGNRLPSYLGSSF
MUL_0456|M.ulcerans_Agy99 CST------------TIWARRVLAGAP-----------------------
TH_2104|M.thermoresistible__bu TVG-----------VVALPLALAFGISSG--------VGAAAGLITAVVA
. . *
MMAR_4949|M.marinum_M AGVSPVIAIGLSHGGGTPS--LLYVYGAVIVAGLFTILIAPIFTKLLRFF
MSMEG_1293|M.smegmatis_MC2_155 AGVSPIIAIGLAHGGGAPS--LLYVYGAVIVAGIFTFLIAPVFIKLLRFF
Mvan_5275|M.vanbaalenii_PYR-1 AGVAPIIAIGLAHGGGTES--LLYVYGAVIVAGVFTFLIAPMFVRLLKFF
MAB_2932c|M.abscessus_ATCC_199 ATLAPVIKIANDHGGGRVG--LLTVYGAVIAAGAFTFLIAPFFARLIRFF
Mflv_0188|M.gilvum_PYR-GCK SVIAPVTAATASHGTGSALGGIIAVGVLLIIIGAVVHVAGTRWIDIT--L
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_2104|M.thermoresistible__bu GLVAAVFGGSHIQVSGPTG-------------------------AMAVIL
MMAR_4949|M.marinum_M PPVVTGTLITIIGLCLVPVGAGDAVTNPRT--GEHDPTNIRWLLYALGTI
MSMEG_1293|M.smegmatis_MC2_155 PPVVTGTLITIIGLCLVPVGAHDAVTNPHT--GEVDPTNLRWFLYALGTI
Mvan_5275|M.vanbaalenii_PYR-1 PPVVTGTLITIIGLCLVPIGALDAVTNPAT--HEPDPTNLRWVLYALGTI
MAB_2932c|M.abscessus_ATCC_199 PPVVTGSVITIIGVSLLPVGIGDATRNPHSPVAAHDPGNGRWLMYALGTI
Mflv_0188|M.gilvum_PYR-GCK PPVVTGAIVALIGFNLAPAAKNNFEQGPLLG---------------FVTL
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_2104|M.thermoresistible__bu APIVAQHGLTSIALVTVLAGLIVLAAGITG--------------LGRAVT
MMAR_4949|M.marinum_M AIIVAIQRVFSGFMATIAVLIGLVVGCVVAYGLGDMSFAKVDEASVIGFT
MSMEG_1293|M.smegmatis_MC2_155 AVIVAIQRIFSGFLATIAVLLGLVIGCVVAYALGDMNFDDVAQANMFGFT
Mvan_5275|M.vanbaalenii_PYR-1 AVIVAIQRLFRGFMSTIAVLLGLVAGCTVAFTLGDMNFDRVAEASMFGFT
MAB_2932c|M.abscessus_ATCC_199 GAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVGEADWIGFT
Mflv_0188|M.gilvum_PYR-GCK VLLVVVLAAFRGLLGRLAIFVAVAAGYLLAVFLGEVDTSGIAAAAWIGLP
MUL_0456|M.ulcerans_Agy99 -------------FDDVGALLDRADRVLAQLPEAEIDAALDGHP------
TH_2104|M.thermoresistible__bu FIPWPVIEGFTLGIAAIIFLQQVPAAFATEAPAGQRTLVAAWHVVTHADW
: : .:
MMAR_4949|M.marinum_M EPFVFGMPKFDFVACLTMIIVLMITSV-ESTGSTLATGEIVGKRIKAAQI
MSMEG_1293|M.smegmatis_MC2_155 QPFLFGMPKFDFVACLTMIIVLMITAV-ESTGSTYATGEIVGKRIKASDI
Mvan_5275|M.vanbaalenii_PYR-1 PPFAFGMPRFDIVAIITMIIVMMIIAV-ESTGSTIATGEIVGKRVRPSDI
MAB_2932c|M.abscessus_ATCC_199 SPFAFGAPRFDVIAVVSLIVVLMVTAV-ESTGAVFATAEIVGKRVRGADI
Mflv_0188|M.gilvum_PYR-GCK D---FQAPTFTLSVLPLFLPAVVALVA-ENIGHVKSVGQMT-KRDMDPLT
MUL_0456|M.ulcerans_Agy99 -----------------------------RIGARADNASSAREQALVAGA
TH_2104|M.thermoresistible__bu TAAVKTLSVVSLVALLMVVLPRLHRSIPESLTAVVAATVIVTVFGISVAT
.
MMAR_4949|M.marinum_M GNVLRADGLATVIGGIFNSFPYTAFSENVGLVRLTRVKSRWVVAAAGVVM
MSMEG_1293|M.smegmatis_MC2_155 GNVLRADGLATTIGGVFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIM
Mvan_5275|M.vanbaalenii_PYR-1 GNVLRADGVATTIGGIFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIM
MAB_2932c|M.abscessus_ATCC_199 AATVRADGIATVIGGTFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIM
Mflv_0188|M.gilvum_PYR-GCK GRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAPYWIAALVA
MUL_0456|M.ulcerans_Agy99 GEAVRAELAEKNRK----------YEEKFGYVYLVCATGRSAEDLLETLT
TH_2104|M.thermoresistible__bu IGELPSQLPTPVLPQADMGAMQTLLGAALAIAALAAIESLLSARVAATMS
: :: .. . . :
MMAR_4949|M.marinum_M IVLGFLPK---VAAVVSAVPSPVLGGAALTLFATVAVVGIQTLGKVDFTD
MSMEG_1293|M.smegmatis_MC2_155 ILLGFLPK---VAAVVSSIPQPVLGGAALTLFATVAVVGIQTLGKVDFTD
Mvan_5275|M.vanbaalenii_PYR-1 ILLGFLPK---VAAIVASIPNPVLGGAALTLFATVAVVGIQTLGKVDFTD
MAB_2932c|M.abscessus_ATCC_199 MVLGVLPK---TAKIVESIPAPVLGGAAMTLFATVAVVGIQTLGKVDFND
Mflv_0188|M.gilvum_PYR-GCK ILLSLCPK---VGAVIAAIPAGVLGGATVVLYGLVGIIGIRIWLTNHVDF
MUL_0456|M.ulcerans_Agy99 DRLDNDPE---TERRVMRSELAKINRLRLQRLLREPA-------------
TH_2104|M.thermoresistible__bu ATGPYHPDRELVGQGMASVASGLFGGMPATGAIARTAVNVRSGARTRLAA
*. . : :.
MMAR_4949|M.marinum_M HRNLIIVTTSLALALWVTS--------------------YPDVAESMPSG
MSMEG_1293|M.smegmatis_MC2_155 HRNLIIVTTSLAAALWATS--------------------YPDVAQALPAG
Mvan_5275|M.vanbaalenii_PYR-1 HRNVIIVTTSLALALLVTS--------------------YPDISSQLPAG
MAB_2932c|M.abscessus_ATCC_199 HRNLIIASTSLAMGMYVQFSQSSGPATVLDHGRGIAVPALPGIDQAVPGL
Mflv_0188|M.gilvum_PYR-GCK SKPVNQMTAAIPLIIGIAD---------------------------FTWS
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_2104|M.thermoresistible__bu IVHSLVLLAVVYLATGPVS------------------------AIPLSAL
MMAR_4949|M.marinum_M VDLIFGSGISIGAVAAIVLNIVFFHTGSHGPRVAGGGSITLHEVNAMTRE
MSMEG_1293|M.smegmatis_MC2_155 IDLLFGSGISIGAISAILLNVVFFHLGGRGARVAGSGTITLDEVNAMTEQ
Mvan_5275|M.vanbaalenii_PYR-1 LDILFGSGISTGAITAIVLNIVFFHIVKKGPRVAGSGSITLDEVNAMTRE
MAB_2932c|M.abscessus_ATCC_199 LQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGGGAIRLAQVNEMTLE
Mflv_0188|M.gilvum_PYR-GCK AGSLTFTGIALGSIAALLIYHGMRLLGFR-PGRERPSTVYADPAGPAPEP
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_2104|M.thermoresistible__bu AGVLMVTSFRMVSLHTARRILRSTRSDALTFVLTALVTITFDLIEAVQIG
MMAR_4949|M.marinum_M RFTEVFGHVVQDVPWVIDRAYEHRPFADTAALREAFQDAVLTGSSEQQME
MSMEG_1293|M.smegmatis_MC2_155 RFKEVFGRVVQNVPWVLERVYTSRPFTDTNALRQAFQDALLAGSADQQLE
Mvan_5275|M.vanbaalenii_PYR-1 RFTEVFGHVVQGVSWAADRAFDQRPFADTAALREAFQDAVLTGNAEQQQE
MAB_2932c|M.abscessus_ATCC_199 QFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDEEQLE
Mflv_0188|M.gilvum_PYR-GCK R-------------------------------------------------
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_2104|M.thermoresistible__bu VLVAAFFALRNVARRSGVTREELPGEPQPGDERIALLRLEGSMFFGVAER
MMAR_4949|M.marinum_M LLNAFHDLGAEDETGRALAVDHVSLSNLDERDHNVVVELASAYREHFGFP
MSMEG_1293|M.smegmatis_MC2_155 LVRAFPDLGAEDETGHALAVDHVALSNLDEDDHNDVVQLATAYREHFGFP
Mvan_5275|M.vanbaalenii_PYR-1 LLDAFHDLGAEDETGQVLAVDHVALSNLDEEDHQDVVTLAAAYREHFGFP
MAB_2932c|M.abscessus_ATCC_199 LIGSFPDLGAEDEAGEMVAVDHTILQTLDEAELNNVVSLATAYREHFGFP
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_2104|M.thermoresistible__bu MSSTISEIEADDIS--VVIIRLSQLGTLDATGANSLAQIATELERRG---
MMAR_4949|M.marinum_M LIICARETERFDRVLKNGWSRMDNSPATERAYALIEAAKIANYRFSDLVA
MSMEG_1293|M.smegmatis_MC2_155 LIICARETQHFDRILQNGWSRIDNSPAAEKSFALIEIAKIVKYRFDDLVA
Mvan_5275|M.vanbaalenii_PYR-1 LIICARETERFDRVLRNGWSRMDNSPATEKAYALIEVAKIANYRFTDLVA
MAB_2932c|M.abscessus_ATCC_199 LVVCARETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFDDLVA
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_2104|M.thermoresistible__bu ----------ITVIIKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIE
MMAR_4949|M.marinum_M DANPIASARLSRLNELH---
MSMEG_1293|M.smegmatis_MC2_155 DANPIAAARFGRLTELR---
Mvan_5275|M.vanbaalenii_PYR-1 DANPIAAARFGRLNELS---
MAB_2932c|M.abscessus_ATCC_199 DANPITAARFGRFEDFHATR
Mflv_0188|M.gilvum_PYR-GCK --------------------
MUL_0456|M.ulcerans_Agy99 --------------------
TH_2104|M.thermoresistible__bu HARSHVARQQTARTTS----