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VGTMVEAITPQQEQSVLAALRSPRRLRTEVLGGLVVALALIPEAISFSIIAGVDPRVGLFASFTMAVTIA IVGGRPAMISAATGAVALVIAPLAHSHGLDYLIAAVILAGVLQLLLGGLGVAKLMRFVPRSVMVGFVNAL AILIFMSQVPHLLGVPWLVYPMVAVGILVIVALPKLTAAIPGPLVAIVLLTAAAIGFGWSVPDVGDEGQL PSSLPSLLIPDVPLTFDTLRIIAPYALAMALVGLLESLMTAKLVDDITDTHSDKSREAVGQGVANVVTGF FGGMGGCAMIGQTMINVKVSGARTRISTFLAGAFLLGLVVGLGDLVAQIPMAALVAVMIMVSVATLDWHS INPKTLRRMPKSETLVMVSTVAVTVATHNLAYGVAVGTLAAMVLFARRVAHFTEVVPVDSGAADTRVYVV TGELFFASSNDMVYQFDYAGDPDNIVIDMSAAHIWDASTVATLDAVTTKYAAKGKTVTIVGMNDSSAQRH AQLSGQLTGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1159 | - | - | 100% (500) | sulphate transporter |
| M. vanbaalenii PYR-1 | Mvan_5693 | - | 3e-57 | 31.71% (492) | sulphate transporter |
| M. vanbaalenii PYR-1 | Mvan_1430 | - | 1e-33 | 27.27% (506) | sulfate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1734 | - | 5e-51 | 30.57% (422) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1119 | - | 9e-56 | 31.98% (494) | sulphate transporter |
| M. tuberculosis H37Rv | Rv1707 | - | 5e-51 | 30.57% (422) | transmembrane protein |
| M. leprae Br4923 | MLBr_02279 | - | 2e-36 | 29.65% (398) | putative transmembrane transport protein |
| M. abscessus ATCC 19977 | MAB_4448 | - | 1e-43 | 26.94% (464) | putative sulfate transporter |
| M. marinum M | MMAR_4750 | - | 0.0 | 79.18% (485) | integral membrane transporter |
| M. avium 104 | MAV_4578 | - | 6e-37 | 28.89% (398) | carbonate dehydratase |
| M. smegmatis MC2 155 | MSMEG_1448 | - | 0.0 | 86.99% (492) | integral membrane transporter |
| M. thermoresistible (build 8) | TH_2104 | - | 1e-55 | 30.77% (494) | sulfate permease |
| M. ulcerans Agy99 | MUL_0321 | - | 0.0 | 78.19% (486) | integral membrane transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1734|M.bovis_AF2122/97 ---------------------------MLQRIARELLSGVAVAIVALPLA
Rv1707|M.tuberculosis_H37Rv ---------------------------MLQRIARELLSGVAVAIVALPLA
Mflv_1119|M.gilvum_PYR-GCK --------MITIGRLGRLLPQRSDYTDLRRSWRADLLAGVTVGVVALPLA
TH_2104|M.thermoresistible__bu ------VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLA
Mvan_1159|M.vanbaalenii_PYR-1 ----MGTMVEAITPQQEQS--VLAALRSPRRLRTEVLGGLVVALALIPEA
MSMEG_1448|M.smegmatis_MC2_155 ------MTSATITPREEQS--VWAALRSPRRLRTEVLAGLVVALALIPEA
MMAR_4750|M.marinum_M ---------------------MLAALRSPTRLRTEVLAGLVVALALIPEA
MUL_0321|M.ulcerans_Agy99 MSSQQVSAVPTIRKAGDPSTAVLAALRSPTRLRTEVLAGLVVALALIPEA
MLBr_02279|M.leprae_Br4923 ---------------------------MRSAIRYDLPASLVVFLVALPLS
MAV_4578|M.avium_104 --------MQDIQRADDALPTASRAERLRGVIRHDLPSSLVVFLVALPLS
MAB_4448|M.abscessus_ATCC_1997 ----------------MPSAPGLFESYDAIKARRDVIAGLTVAAISLPQA
:: ..:.* :* :
Mb1734|M.bovis_AF2122/97 IAFGITATGTSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTGPITVVAT
Rv1707|M.tuberculosis_H37Rv IAFGITATGTSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTGPITVVAT
Mflv_1119|M.gilvum_PYR-GCK LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSSVQVSGPTGAMAVVLA
TH_2104|M.thermoresistible__bu LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSHIQVSGPTGAMAVILA
Mvan_1159|M.vanbaalenii_PYR-1 ISFSIIAG---VDPRVGLFASFTMAVTIAIVGGRPAMISAATGAVALVIA
MSMEG_1448|M.smegmatis_MC2_155 ISFSIIAG---VDPRVGLFASFTMAVTIAIVGGRPAMISAATGAVALVVA
MMAR_4750|M.marinum_M ISFSIIAG---VDPRVGLFASFTMAVTIAVVGGRPAMISAATGAIALVIA
MUL_0321|M.ulcerans_Agy99 ISFSIIAG---VDPRVGLFASFTMAVTIAVVGGRLAMISAATGAIALVIA
MLBr_02279|M.leprae_Br4923 LGIAIASD---TPVLAGLIAAIVGGIVAGALGGSPLQVSGPAAGLTVVIA
MAV_4578|M.avium_104 LGIAIASN---APVLAGLIAAIVGGIVVGALGGSPLQVSGPAAGLTVVVA
MAB_4448|M.abscessus_ATCC_1997 MAYALIAG---VDPKYGVYSAIVVTAIASIFGSSSHLINGPTSAISLLVF
:. .: : *: :. . .*. :...:. ::::
Mb1734|M.bovis_AF2122/97 ATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRYVPHPVIS
Rv1707|M.tuberculosis_H37Rv ATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRYVPHPVIS
Mflv_1119|M.gilvum_PYR-GCK PIVAMHG-------LGSIALVTVLAGLLVLLAGVTGLGRAVTFIPWPVIE
TH_2104|M.thermoresistible__bu PIVAQHG-------LTSIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIE
Mvan_1159|M.vanbaalenii_PYR-1 PLAHSHG-------LDYLIAAVILAGVLQLLLGGLGVAKLMRFVPRSVMV
MSMEG_1448|M.smegmatis_MC2_155 PLVRSHG-------LDYLIATVILAGLLQLVLGGLGVARLMRFVPRSVMV
MMAR_4750|M.marinum_M PLAREHG-------ADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMV
MUL_0321|M.ulcerans_Agy99 PLAREQG-------ADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMV
MLBr_02279|M.leprae_Br4923 DLISDFG-------WGVTCFITVAAGVLQVLLGLSRVARAALAISPVVVH
MAV_4578|M.avium_104 GLVSDFG-------WGVTCFITVAAGAVQVLLGLSRVARAALAISPVVVH
MAB_4448|M.abscessus_ATCC_1997 SSLAFLDPENRTGLFEALFLLGVLVGTIQILIAVFKLGDLTRYISESVVI
. : .* . : . :. :. *:
Mb1734|M.bovis_AF2122/97 GFMGGIAILIIMTQLDQVRSS-------SLLVLVTVVLLLA-----SGRF
Rv1707|M.tuberculosis_H37Rv GFMGGIAILIIMTQLDQVRSS-------SLLVLVTVVLLLA-----SGRF
Mflv_1119|M.gilvum_PYR-GCK GFTLGIAAIIFLQQIPAAFAAGGPPGERTLPAAWHVVTHAD-----WSEA
TH_2104|M.thermoresistible__bu GFTLGIAAIIFLQQVPAAFATEAPAGQRTLVAAWHVVTHAD-----WTAA
Mvan_1159|M.vanbaalenii_PYR-1 GFVNALAILIFMSQVPHLLGVP----------------------------
MSMEG_1448|M.smegmatis_MC2_155 GFVNALAILIFLAQIPHLLGVP----------------------------
MMAR_4750|M.marinum_M GFVNALAILIFLSQLPHLLGVP----------------------------
MUL_0321|M.ulcerans_Agy99 GFVNALAILIFLSQVPHLLGVP----------------------------
MLBr_02279|M.leprae_Br4923 AMLAGVGITIALQQAHVLLGGKSKSTAWHNAIGLPSQILGA-----HRPG
MAV_4578|M.avium_104 AMLAGIGITIALQQTHVLLGGKSKSTAWHNLIGLPGQIIGA-----HRPG
MAB_4448|M.abscessus_ATCC_1997 GFMASAALLLAIGQLANAIGVRDKGDGHMQVLQRAWLTLFHGDAVNYRAL
.: . . : : * .
Mb1734|M.bovis_AF2122/97 IKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVS------INRTVD----
Rv1707|M.tuberculosis_H37Rv IKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVS------INRTVD----
Mflv_1119|M.gilvum_PYR-GCK VKSLGVIAFVVALMVALPRIHRAIPESLAAVVGATVAVGVLGISVA----
TH_2104|M.thermoresistible__bu VKTLSVVSLVALLMVVLPRLHRSIPESLTAVVAATVIVTVFGISVA----
Mvan_1159|M.vanbaalenii_PYR-1 WLVYPMVAVGILVIVALPKLTAAIPGPLVAIVLLTAAAIGFGWSVP----
MSMEG_1448|M.smegmatis_MC2_155 WLVYPMVAVALVIIVALPKLTAAVPGPLVAIVLLTAATIGFGWSVP----
MMAR_4750|M.marinum_M PVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEIP----
MUL_0321|M.ulcerans_Agy99 AVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEIL----
MLBr_02279|M.leprae_Br4923 VILGVLVITILIAWRWVPARVARIPGPLVAIVVTTLVSVVFPFHVS----
MAV_4578|M.avium_104 VLLGVLVIVILVAWRWVPAKVRRVPGPLVAIVAVTVISVVFPFHVR----
MAB_4448|M.abscessus_ATCC_1997 FLSVTAVALAVLLRRLVQRYELPQIDMLLVLIVTAVIAYAYGWTVPDGTG
: * . :
Mb1734|M.bovis_AF2122/97 --YIG---EIPQAMPSFDFPQVAN--STMLQVLLSAVAIALLGSLDSLLT
Rv1707|M.tuberculosis_H37Rv --YIG---EIPQAMPSFDFPQVAN--STMLQVLLSAVAIALLGSLDSLLT
Mflv_1119|M.gilvum_PYR-GCK --TIG---ELPSHLPAPMLPQIVP--GALRDLFGAALAIAALAAIESLLS
TH_2104|M.thermoresistible__bu --TIG---ELPSQLPTPVLPQADM--GAMQTLLGAALAIAALAAIESLLS
Mvan_1159|M.vanbaalenii_PYR-1 --DVGDEGQLPSSLPSLLIPDVPLTFDTLRIIAPYALAMALVGLLESLMT
MSMEG_1448|M.smegmatis_MC2_155 --DVADEGRLPSSLPSLLIPNVPLNLDTLKIIAPYALTMAVVGLLESLMT
MMAR_4750|M.marinum_M --NVGDEGQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLT
MUL_0321|M.ulcerans_Agy99 --NVGDEGQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLT
MLBr_02279|M.leprae_Br4923 --RIQ--VDNRSSLDVLQLPKLPD--GHWGAVVLGVITVALIASVESLLS
MAV_4578|M.avium_104 --RID--LDG-SPLDALQLPDLPH--GNWSGVAVGVITVALIASVESLLS
MAB_4448|M.abscessus_ATCC_1997 HTDVKISGKIPASLPEFHIPEVQVS--TLGELSHGALAIAFIGLIEALSI
: : .*. : .:::* :. :::*
Mb1734|M.bovis_AF2122/97 SLVMDNIRGTR-HRSNKELIGQGIGNIAAGLFGGLAGAGATVRSVVNVRN
Rv1707|M.tuberculosis_H37Rv SLVMDNIRGTR-HRSNKELIGQGIGNIAAGLFGGLSGAGATVRSVVNVRN
Mflv_1119|M.gilvum_PYR-GCK ARVAATMAPTGPYDPDRELVGQGLASVASGAFGGMPATGAIARTAVNVRS
TH_2104|M.thermoresistible__bu ARVAATMSATGPYHPDRELVGQGMASVASGLFGGMPATGAIARTAVNVRS
Mvan_1159|M.vanbaalenii_PYR-1 AKLVDDITDTH-SDKSREAVGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MSMEG_1448|M.smegmatis_MC2_155 AKLVDDITDTH-SNKSREALGQGAANIVTGFFGGMGGCAMIGQTMINVKA
MMAR_4750|M.marinum_M AKLVDDITDTH-SNKTREAWGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MUL_0321|M.ulcerans_Agy99 AKLVDDITDTH-SNKTREAWGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MLBr_02279|M.leprae_Br4923 AVSLDKMHNGPRTDLNRELIGQGAANIVSGAIGGLPITGVIVRSSTNVIA
MAV_4578|M.avium_104 AVSVDRMHNGPRTDFNRELVGQGAANMISGAVGGLPVTGVIVRSSTNVNA
MAB_4448|M.abscessus_ATCC_1997 AKAIAHHTGQQ-IDYNRQILAEGLANLAGGFFQSLPGSGSLSRSAINYQS
: :: .:* ..: * . .: . :: *
Mb1734|M.bovis_AF2122/97 -GGQTALSAATHSVVLFVFVAGLGAVVQYIPLAVLSGILILVAVGMFDWH
Rv1707|M.tuberculosis_H37Rv -GGQTALSAATHSVVLFVFVAGLGAVVQYIPLAVLSGILILVAVGMFDWH
Mflv_1119|M.gilvum_PYR-GCK -GARTRLAAVVHSVVLLGVVYLATGPVAAIPLAALSGVLMVTSFRMISRS
TH_2104|M.thermoresistible__bu -GARTRLAAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMVSLH
Mvan_1159|M.vanbaalenii_PYR-1 SGARTRISTFLAGAFLLGLVVGLGDLVAQIPMAALVAVMIMVSVATLDWH
MSMEG_1448|M.smegmatis_MC2_155 CGARTRISTFSAGAFLLGLVVGLGDIVGRIPMAALVAVMVMVSVGTFDWH
MMAR_4750|M.marinum_M SGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWH
MUL_0321|M.ulcerans_Agy99 PGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWH
MLBr_02279|M.leprae_Br4923 -GAKSRASSIMHGIWILLFTIPFAGLVDQIPSAALAGLLIVVGVQLLKPA
MAV_4578|M.avium_104 -GARSRASAIMHGVWILLFTIPFAGLVDEIPTAALAGLLIVIGIQLLKPA
MAB_4448|M.abscessus_ATCC_1997 -GAATRFSGIVSAATVTIALLLFAPLLRYIPQAALAGLLLVTAVRLVDFH
*. : : . : : ** :.* .:::: .. ..
Mb1734|M.bovis_AF2122/97 AMR--KAHVSPRGDVIVMFTTMIITVVVD-LTIAVMVGIALSLLVHRLRS
Rv1707|M.tuberculosis_H37Rv AMR--KAHVSPRGDVIVMFTTMIITVVVD-LTIAVMVGIALSLLVHRLRS
Mflv_1119|M.gilvum_PYR-GCK TMR--KILTSTRSDATTFVLTAVVTVCFD-LIEAVQIGILVAAFFALRSV
TH_2104|M.thermoresistible__bu TAR--RILRSTRSDALTFVLTALVTITFD-LIEAVQIGVLVAAFFALRNV
Mvan_1159|M.vanbaalenii_PYR-1 SINPKTLRRMPKSETLVMVSTVAVTVATHNLAYGVAVGTLAAMVLFARRV
MSMEG_1448|M.smegmatis_MC2_155 SINPKTLRRMPKSETTVMLATVAVTVATGNLAYGVAVGTLTAMVLFARRV
MMAR_4750|M.marinum_M SIAPATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRV
MUL_0321|M.ulcerans_Agy99 SIAPATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRV
MLBr_02279|M.leprae_Br4923 HIET----ALRNGDLAVYLVTAVCVVFLN-LLHGVMIGLAVAIALTGWRV
MAV_4578|M.avium_104 HIET----AMKHGDLAVYVVTAVSVIFLN-LLHGVMIGLALAIALTGWRV
MAB_4448|M.abscessus_ATCC_1997 RLVY--AIKASRYDAGLVIITALVGVAVN-LDTAVLVGVVLSILLFVPRA
. : . * : * .* * : .
Mb1734|M.bovis_AF2122/97 RQRKAKVTQDDTG-------------------TYRIDGPLSFLSVDGVFG
Rv1707|M.tuberculosis_H37Rv RQRKAKVTQDDTG-------------------TYRIDGPLSFLSVDGVFG
Mflv_1119|M.gilvum_PYR-GCK ARRSSVVREELPAPHR---------PGDEEIALLRLDGAMFFGAAERISN
TH_2104|M.thermoresistible__bu ARRSGVTREELPGEPQ---------PGDERIALLRLEGSMFFGVAERMSS
Mvan_1159|M.vanbaalenii_PYR-1 AHFTEVVPVDS---------------GAADTRVYVVTGELFFASSNDMVY
MSMEG_1448|M.smegmatis_MC2_155 AHLTEVTTVGQ---------------PDPDTRVYAVRGELFFASSNDLVY
MMAR_4750|M.marinum_M AHFMTVERIVESDTG-----------SAAETVVYRVSGELFFASSNDLVY
MUL_0321|M.ulcerans_Agy99 AHFMTVERIVESDTG-----------SAAETVVYRVSCELFFASSNDLVY
MLBr_02279|M.leprae_Br4923 IRARVEAQPVGDEWH-----------------VLVAG-ACTFLALPRLTR
MAV_4578|M.avium_104 IRAKIEAAQLDGEWR-----------------VTIEGAACTFLALPRLTR
MAB_4448|M.abscessus_ATCC_1997 AKLKAAELVVTDEGVIRERTPQDRPTGAGAPVIYDLEGELFFGAAPELDR
: * :
Mb1734|M.bovis_AF2122/97 SLR----DGRED----VSLDLQHVTYLDTSGAQALLYFIDHSEKDGVAVS
Rv1707|M.tuberculosis_H37Rv SLR----DGRED----VSLDLQHVTYLDTSGARALLYFIDHSEKDGVAVS
Mflv_1119|M.gilvum_PYR-GCK AIV----DGDHPRTSVVIIRMSQLGMLDATGANTLAQICTELEARGITVI
TH_2104|M.thermoresistible__bu TIS----EIEADDISVVIIRLSQLGTLDATGANSLAQIATELERRGITVI
Mvan_1159|M.vanbaalenii_PYR-1 QFD----YAGDPDN--IVIDMSAAHIWDASTVATLDAVTTKYAAKGKTVT
MSMEG_1448|M.smegmatis_MC2_155 QFD----YVGDPDN--IVIDMSQAHIWDASTVATLDAITTKYAAKGKTVR
MMAR_4750|M.marinum_M QFN----YVDDPDN--VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVE
MUL_0321|M.ulcerans_Agy99 QFN----YVDDPDN--VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVE
MLBr_02279|M.leprae_Br4923 VLA----SVPPCTR---VTVNISVNYLDHAAHQAIHDWQRQHHATGGTVH
MAV_4578|M.avium_104 VLA----SVPRGAT---VTVAIAVHYLDHAAHQAITDWQRQQEATGGTVR
MAB_4448|M.abscessus_ATCC_1997 YLESLHTRIRDEHLKVVILRLKRVRHPDVVCIERLEHFIREQQQLGVTVL
: * : . * *
Mb1734|M.bovis_AF2122/97 IKRIPPRLESQLTALADNEQRDKLRTVLESA-------------------
Rv1707|M.tuberculosis_H37Rv IKRIPPRLESQLTALADNEQRDKLRTVLESA-------------------
Mflv_1119|M.gilvum_PYR-GCK IKGVRPEHSALLANVGVFESLRHERHLVDTLDEAIEHARTHARRQPH---
TH_2104|M.thermoresistible__bu IKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIEHARSHVARQQTART
Mvan_1159|M.vanbaalenii_PYR-1 IVGMNDSSAQRHAQLSGQLTGG----------------------------
MSMEG_1448|M.smegmatis_MC2_155 IIGMNDNSAQRHARLSGQLTGAH---------------------------
MMAR_4750|M.marinum_M IIGLNQDSAERHGRLSGQFGAEH---------------------------
MUL_0321|M.ulcerans_Agy99 IIGLNQDSAERHGRLSGQFGAEH---------------------------
MLBr_02279|M.leprae_Br4923 ING-VVETGHFSRCAMGDLIGPEQQPEAAA--------------------
MAV_4578|M.avium_104 IEGAVVATGRRD-----EPQVEAEMPGAAA--------------------
MAB_4448|M.abscessus_ATCC_1997 LAGVRPDSLALLENVGFTHWLPPEQVFPEEEKEFSATLRAVRYAQSRLEE
:
Mb1734|M.bovis_AF2122/97 ----------------
Rv1707|M.tuberculosis_H37Rv ----------------
Mflv_1119|M.gilvum_PYR-GCK ----------------
TH_2104|M.thermoresistible__bu TS--------------
Mvan_1159|M.vanbaalenii_PYR-1 ----------------
MSMEG_1448|M.smegmatis_MC2_155 ----------------
MMAR_4750|M.marinum_M ----------------
MUL_0321|M.ulcerans_Agy99 ----------------
MLBr_02279|M.leprae_Br4923 ----------------
MAV_4578|M.avium_104 ----------------
MAB_4448|M.abscessus_ATCC_1997 EPPNPAANPEKLYYLV