For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VVNPEVPESDSDVAARVTVEIRLRAVTEVNDGAPVGEVAERYGVTRQTVTAWRKRYEAGGLEALADQSRR PHSSPGRISPDVEALICEMRRHHRRWGARRIAYELKLEIGKQAPSRSTTHRVLVRNGLVNSQEQQHKRVY KRWAREAPMHLWQLDIVGGVFLVNGREHKMLTAIDDHSRFVVAAAVLPVPSGPAVCDAFLAAIARWGAPF EVLTDNGKQFTGKFTRPLPAEVLFERICRDNGITARLTKRRSPTTTGKVERFHKTLRRELLDETGAFESI EAAQAAIDEWVHAYNTVRPHQSLDMATPASLFRSRVTDPELHPPDLGHRRQIFGVLIR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0458 | - | - | 100% (338) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_0573 | - | e-109 | 62.18% (312) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_2928 | - | 3e-17 | 27.34% (267) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2835 | - | 3e-10 | 28.12% (160) | transposase |
| M. gilvum PYR-GCK | Mflv_4763 | - | 2e-12 | 26.98% (278) | integrase catalytic subunit |
| M. tuberculosis H37Rv | Rv2812 | - | 3e-16 | 26.59% (252) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4106 | - | 8e-80 | 52.53% (297) | transposase for ISMyma05 |
| M. avium 104 | MAV_3347 | - | 2e-19 | 29.31% (348) | transposase |
| M. smegmatis MC2 155 | MSMEG_6600 | - | 1e-18 | 30.65% (323) | transposase |
| M. thermoresistible (build 8) | TH_3163 | - | 2e-29 | 32.34% (337) | PUTATIVE putative Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0458|M.vanbaalenii_PYR-1 -----------------MVNPEVPESDSDVAARVTVEIRLRAVTEVNDGA
MMAR_4106|M.marinum_M ------------------MLQELRMS----------EMRYRAVLEVLDGA
MAV_3347|M.avium_104 -MKCELLKNAQLTPEVFVSHRNAPLSETG-------RLRL-ARCVVEDGW
MSMEG_6600|M.smegmatis_MC2_155 -----------------MVHRNAPLSETG-------RLRL-ARCVVDDGW
Mb2835|M.bovis_AF2122/97 MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASRE
Rv2812|M.tuberculosis_H37Rv MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASRE
TH_3163|M.thermoresistible__bu -----------------MAQKVTAMDIR------------MAAAVAGEID
Mflv_4763|M.gilvum_PYR-GCK MPASGDHRVDVAPLDCPVRRHESQRGQTAQGTRSRERPAQEAGRQPGPRH
Mvan_0458|M.vanbaalenii_PYR-1 PVGE-------VAERYGVTRQTVTAWRKRY-EAGGLEALADQSRRPHSSP
MMAR_4106|M.marinum_M PVTA-------VARRFGVSRQTVHAWLRRYAEEGAALNLEDRSSRPHRCP
MAV_3347|M.avium_104 SLRR-------AAERFQVAVTTAQRWASRYRELGPAG-MADRSSRPLRSP
MSMEG_6600|M.smegmatis_MC2_155 SRRR-------AAERFQVSVTTVCRWVNRYLELGEAG-MADRSSRPHHSP
Mb2835|M.bovis_AF2122/97 HTDP-------FGRRVRISRQTIDRWIRGWRAGGFDALVPN----PRQCT
Rv2812|M.tuberculosis_H37Rv HTDP-------FGRRVRISRQTIDRWIRGWRAGGFDALVPN----PRQCT
TH_3163|M.thermoresistible__bu NVAE-------FCRRRKISRQTFYKFRRRFRDSGIEG-LQELSRRPLTSP
Mflv_4763|M.gilvum_PYR-GCK RHAQGDFGGKLLTPNRKRSAVIALRERFGVSERRACTVVGLHRSTMRLTP
. : : .
Mvan_0458|M.vanbaalenii_PYR-1 GRISPDVEALICEMRR----HHRRWGARRIAYELKLEIG--KQAPSRST-
MMAR_4106|M.marinum_M HQMPVEVEARVLTLRD----AHPRWGPTRIVYELQRDVV--PVVPGRSS-
MAV_3347|M.avium_104 NQTPTRTERRIIKVR-----VLRRWGPARIAYLLGLNVSTVHRVLTRYK-
MSMEG_6600|M.smegmatis_MC2_155 NRTPTRTERRIIGVR-----VTRRWGPARIAYLLRLNVSTVHNVLRRYR-
Mb2835|M.bovis_AF2122/97 PRTPAEVLELAVALRR----ENPQRTAAAIRRILRTQLG---WAPDERT-
Rv2812|M.tuberculosis_H37Rv PRTPAEVLELAVALRR----ENPQRTAAAIRRILRTQLG---WAPDERT-
TH_3163|M.thermoresistible__bu GQTPVEVEDLIVLRRKQLIEQGRDHGAQSIVWSFERDGVTVPSVSTVWQR
Mflv_4763|M.gilvum_PYR-GCK APVTTEEAELRAWLRR-FSTDRPRWGWRRAAKMARRAGWKANNKRIRRLW
. *
Mvan_0458|M.vanbaalenii_PYR-1 THRVLVRNGLVNSQEQQHKR-VYKRWAREAPMHLWQLDIVGGVFLVNGRE
MMAR_4106|M.marinum_M VYRALVRNGRIDPAKRRRRRSDYKRWERGRPMELWQMDVVGGLHLRDGIE
MAV_3347|M.avium_104 LAKLRWLDRATGQVVRRMEAACCGDLVHVDVKKLGKIPAGGGWRMLGRTV
MSMEG_6600|M.smegmatis_MC2_155 IARLRWLDRATGRVVRRMESAACGDLVHADVKKLGKIPAGGGWRMLGRTA
Mb2835|M.bovis_AF2122/97 LQRNFHRLGLTG-ATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLR-K
Rv2812|M.tuberculosis_H37Rv LQRNFHRLGLTG-ATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLR-K
TH_3163|M.thermoresistible__bu GWQILSRRGAITPQPQKRPKSATKRFVFSCPNECWQSDWTG-WVLADGSP
Mflv_4763|M.gilvum_PYR-GCK REEGLRVPQRRRKKRLTGIGVAVGAMSPIRPNVIWAMDFQFDTTADGR-T
.
Mvan_0458|M.vanbaalenii_PYR-1 HKMLTAIDDHSRFVVAAAVLPV----------PSGPAVCDAFLAAIAR--
MMAR_4106|M.marinum_M VKVVTGIDDNSRFVVSAKVVAR----------ATARPVCAALLEALRR--
MAV_3347|M.avium_104 GNRNAQADKTSGERSKHRHPLRGYHFLHTAIDAHSRLAYSELLTDERKET
MSMEG_6600|M.smegmatis_MC2_155 GRKNSLADKSSGVKTRNGDPARGYHFLHSALDAHSRLVYSEMLADERKDT
Mb2835|M.bovis_AF2122/97 TYLFAFLDDHSRLVPGYRG-------------------------------
Rv2812|M.tuberculosis_H37Rv TYLFAFLDDHSRLVPGYRWGHA---------------EDTVRLAAALR--
TH_3163|M.thermoresistible__bu AGIAGSLDDHSRYVPALRACAG---------DADAQLVWETMLAGIAECG
Mflv_4763|M.gilvum_PYR-GCK LKMLNVIDEFTREALAIEVDRA--------------INADGVVDVLDR--
*. :
Mvan_0458|M.vanbaalenii_PYR-1 ----WGAPFEVLTDNGKQFTGKFTR-PLPAEVLFERICRDNGITARLTKR
MMAR_4106|M.marinum_M ----HGVPEQILTDNGKVFTGRFGPGGSSAEVLFDRVCVENGIGHLLTAP
MAV_3347|M.avium_104 AAAFWLRAQAWFTTCGFTVRKVLTDNGSCYRSHAFRDALG-DIEHRRTRP
MSMEG_6600|M.smegmatis_MC2_155 ASEFWKRANSWFFEQGVIVRTVLTDNGSCYRSHSFREALGDDIEHRRTRP
Mb2835|M.bovis_AF2122/97 ------------PCRG------------------------------HGAA
Rv2812|M.tuberculosis_H37Rv ---------PALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTP
TH_3163|M.thermoresistible__bu ------IPSMSLTDNGIVYTGRFHAHQSAFETN----LRALGVQTINATP
Mflv_4763|M.gilvum_PYR-GCK ----------LALTYGAPHYVRFDNGPEFVANAVADWCRFNSAGSLFIDP
*
Mvan_0458|M.vanbaalenii_PYR-1 RSPTTTGKVERFHKTLRRELLDET---------GAFESIEAAQAAIDEWV
MMAR_4106|M.marinum_M RSPTTTGKVERLHKTMRAEIFAEVD--------GVFDAIAELQAAIDRWV
MAV_3347|M.avium_104 YRPQTNGKVERFHRTLADEWAYAR----------LYRSDAERCAEFPRWL
MSMEG_6600|M.smegmatis_MC2_155 YRPQTNGKVERFHRTLADEWAYAR----------LYTSDEQRCQEYPRWL
Mb2835|M.bovis_AF2122/97 GRRTAPG-------------------------------------------
Rv2812|M.tuberculosis_H37Rv GRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWV
TH_3163|M.thermoresistible__bu FHPQTCGKIERFWQTLKKWLTARDP----------ATTIAELNALLEQFR
Mflv_4763|M.gilvum_PYR-GCK GSPWQNAWIESFNGRLRDELLNLWR----------FDSLLEARVIIEDWR
.
Mvan_0458|M.vanbaalenii_PYR-1 HAYNTVRPHQSLDMATPASLFR-------------SRVTDPELHP-----
MMAR_4106|M.marinum_M QYYNTARPHQSLGMVAPAARFALAAGPDLSVVEPVAAVPAEGQHPGALVD
MAV_3347|M.avium_104 HTYNHHRGHTALGGQPPATRVP----------------NLSGQYI-----
MSMEG_6600|M.smegmatis_MC2_155 HTYNHHRGHTALGGQPPASRVP----------------NLSGQYT-----
Mb2835|M.bovis_AF2122/97 ---------------------AG------------------LPR------
Rv2812|M.tuberculosis_H37Rv ETVYHRSVHSETGQTPLARWSAGG--------------PIPLPAPETLTE
TH_3163|M.thermoresistible__bu TFYNHQRPHRAHRGALPAEVFAAG--------------DKARPADRPVPA
Mflv_4763|M.gilvum_PYR-GCK RDYNANRPHSAHGELTPAEFALQWT-------------TTHQPQVA----
Mvan_0458|M.vanbaalenii_PYR-1 -PDLGHRRQI-------------------------------------FGV
MMAR_4106|M.marinum_M LRDAGVRRWVNRHGSISVAGFRYRVPIVLAGEPVSVVVADNLVSIYHHDV
MAV_3347|M.avium_104 --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155 --------------------------------------------------
Mb2835|M.bovis_AF2122/97 ----RAQRGVCR--------------------------------------
Rv2812|M.tuberculosis_H37Rv AFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRL
TH_3163|M.thermoresistible__bu PVIVSRHTVGPTSGYVFVAPYKVNVGLRWAGHECDIIRDGQHITILSGTT
Mflv_4763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0458|M.vanbaalenii_PYR-1 LIR-----------------------------------------------
MMAR_4106|M.marinum_M LVASHVQHRKTDN---TTGVVRQGRRTARPVTSGIVVTRVVDSNGDVSFA
MAV_3347|M.avium_104 --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155 --------------------------------------------------
Mb2835|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv AGAPMRRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELA
TH_3163|M.thermoresistible__bu LVRSFTADPTRNYQRGDKTTRTYRTREPKPPS------------------
Mflv_4763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0458|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4106|M.marinum_M GTMYRAGRVWRGKQVEVSIVAESVQIACAGAIVRTHAIRHDRAKEHGAFA
MAV_3347|M.avium_104 --------------------------------------------------
MSMEG_6600|M.smegmatis_MC2_155 --------------------------------------------------
Mb2835|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv RGVNYTALTGAADQIPGQLDLLTGQEAQPK--------------------
TH_3163|M.thermoresistible__bu --------------------------------------------------
Mflv_4763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0458|M.vanbaalenii_PYR-1 -------------------------------------
MMAR_4106|M.marinum_M TPHGRPRKPRQDAPDGPGAKATPLRGRPEGRALTPAP
MAV_3347|M.avium_104 -------------------------------------
MSMEG_6600|M.smegmatis_MC2_155 -------------------------------------
Mb2835|M.bovis_AF2122/97 -------------------------------------
Rv2812|M.tuberculosis_H37Rv -------------------------------------
TH_3163|M.thermoresistible__bu -------------------------------------
Mflv_4763|M.gilvum_PYR-GCK -------------------------------------