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VSEAVIVDADNIGEAEAALSAAYTAMRLVSDRDVPSGRTRIFRTRVGPLTVDDAEFDFHVIADMDPSEDV LLCRVRGGMLGGHLPGRSPERHGAGTVLAFGGRRGERIYGDIDHARYDTIVLDRNLLAQVASGGLDAAGE PVDLTSLAPVSEEANRHLADVMSHLRRDVASNAHAASQPLVTGPLLRYLAGCVLAAFPNTAAAPPRVQDS SPRLLERALAFIDDNADKDISLGDIAAAARVTPQSVAAMFRRHLSCTPKEYLRKVRLDHAHRDLIANNPA TATVADIAARWGFGVVEAFAVYYRGRYGVHPETTLAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0336 | - | - | 100% (317) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0118 | - | 3e-45 | 37.58% (314) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2363 | - | 4e-14 | 35.04% (117) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 2e-05 | 29.63% (81) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3472 | - | 4e-62 | 41.48% (311) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv1931c | - | 2e-05 | 29.63% (81) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2899c | - | 3e-06 | 32.99% (97) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 1e-05 | 29.82% (114) | transcriptional regulatory protein |
| M. avium 104 | MAV_4063 | - | 4e-34 | 32.98% (282) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_2260 | - | 9e-12 | 26.73% (217) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3937 | - | 1e-39 | 38.05% (318) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | MUL_2902 | - | 4e-05 | 29.82% (114) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0336|M.vanbaalenii_PYR-1 ------------------------------------------------MS
Mflv_3472|M.gilvum_PYR-GCK --------------------------------MRHCSARRGRKRLPDATA
TH_3937|M.thermoresistible__bu -------------------------------VSDDTMVATAERQGPITRS
Mb1966c|M.bovis_AF2122/97 -----------------------------------MVIVGFPG-------
Rv1931c|M.tuberculosis_H37Rv -----------------------------------MVIVGFPG-------
MMAR_2855|M.marinum_M -------------------------------MARKVVIVGFPGVQPLDVV
MUL_2902|M.ulcerans_Agy99 -------------------------------MARKVVTVGFPGVQPLDVV
MAV_4063|M.avium_104 -----MGLTTMTVRDDGAPVGAPAEAARSDYGPVDPVLAVNGERRARPVA
MAB_2899c|M.abscessus_ATCC_199 MRSARGPHSGEPGRSGEPHSGRLGRSGEPHSGRLGRSGEPHSGRLGRSGE
MSMEG_2260|M.smegmatis_MC2_155 --------------MSRLTRLGFIDIRRTSDPVRRKVRSRGVPPALADHE
Mvan_0336|M.vanbaalenii_PYR-1 EAVIVDADNIGEAEAALSAAYTAMRLVSDRDVPSGRTRIFRTRVGPLTVD
Mflv_3472|M.gilvum_PYR-GCK GTLLIDARDIDDAEAQISAAFTTFRIRAAAPARSTRIQVWRNYAGSMGVD
TH_3937|M.thermoresistible__bu RTELTDPSEVGDFLEAVYGVR-VSRVRPPRSHDGPLLTHVRADAGSFIVD
Mb1966c|M.bovis_AF2122/97 ----------------------------------------------DPVD
Rv1931c|M.tuberculosis_H37Rv ----------------------------------------------DPVD
MMAR_2855|M.marinum_M GPFEVFAGASLLSEGGYDVALASIDERPVATGIGLEFMTTRLPDPSAPVD
MUL_2902|M.ulcerans_Agy99 GPFEVFAGASLLSEGGYDVALASIDERPVATGIGLEFMTTRLPDPSAPVD
MAV_4063|M.avium_104 VEYKQFRGADAQSARRFFATAYDPGWRIAGVTNHCVVSHRRSDTGSMTVD
MAB_2899c|M.abscessus_ATCC_199 PHSVVVLALPGTIGFDLATAVEVFRRVYLADGSRPYLVRVCGTEPVVSAG
MSMEG_2260|M.smegmatis_MC2_155 IFYTEDVREAARLVGRTLSPLTLTVDAADAGGFAATMHGVRLRNVSLLYL
Mvan_0336|M.vanbaalenii_PYR-1 DAEFDFHVIADMDPSEDVLLCRVRGGMLGGHLPGRSPER-----HGAGTV
Mflv_3472|M.gilvum_PYR-GCK DVEYTYDLTYDMEAPEQILLCRMLSGVFEETHHGQPTRR-----HGIGTA
TH_3937|M.thermoresistible__bu RLHIAGELHTTADPIHKVVTLWPTSGRVVGRCAGLEG-R-----AGAGEI
Mb1966c|M.bovis_AF2122/97 TVILPGGAGVDAARSEPALIDWVKAVSGTARR----------------VV
Rv1931c|M.tuberculosis_H37Rv TVILPGGAGVDAARSEPALIDWVKAVSGTARR----------------VV
MMAR_2855|M.marinum_M TVVLPGGGGVDAARDNVALMDWVKAAAGTARR----------------VV
MUL_2902|M.ulcerans_Agy99 TVVLPGGGGVDAARDNVALMDWVKAAAGTARR----------------VV
MAV_4063|M.avium_104 EVAIQGRMTLEIPAGDTVVVIQPRAGALNVAGG-----------PLATPD
MAB_2899c|M.abscessus_ATCC_199 PFGIATDLGLEAVSEAETIVVPARDNPTAPLPEGVLDALRGAYERGTRIA
MSMEG_2260|M.smegmatis_MC2_155 DLHVAATLDIPESGRYFAVHMPLNGSATVTHPAAEFDAG--------TTR
:
Mvan_0336|M.vanbaalenii_PYR-1 LAFGGRRGERIYGDIDHARYDTIVLDRNLLAQVASGGLDAAG-EPVDLTS
Mflv_3472|M.gilvum_PYR-GCK IAFGAIQSP-SSGRLEKTRYHMISVPREALGQVAG---DHPGSDAVRLTS
TH_3937|M.thermoresistible__bu ILSG-QPDLVRQTHCDDLAATVILLDPALVAHVASGSAGDDAAAAIRFAS
Mb1966c|M.bovis_AF2122/97 TVCTGAFLAAEAGLLG--RTPSDDALG--LCRTFRPR-ISGRSGRCRPDL
Rv1931c|M.tuberculosis_H37Rv TVCTGAFLAAEAGLLG--RTPSDDALG--LCRTFRPR-ISGRSGRCRPDL
MMAR_2855|M.marinum_M TVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIRSSP
MUL_2902|M.ulcerans_Agy99 TVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIRSSP
MAV_4063|M.avium_104 FPLLVAHGMACVLHCHGARFDVVTIAAEVLQKVAAEW-HTALSQQTQFLN
MAB_2899c|M.abscessus_ATCC_199 SICAGAFTLAEAGILDGKRATTHWLAADLFRERYPAVHLDADVLYVD-EG
MSMEG_2260|M.smegmatis_MC2_155 SLVTSPGDPVRMSFAHDSPQMLVRIEEEAMNAHLTRLLGRNLVGPLKFEP
.
Mvan_0336|M.vanbaalenii_PYR-1 LAPVSEEANRHLADVMSHLRRDVASNAHAASQPLVTGPLLRYLAGCVLAA
Mflv_3472|M.gilvum_PYR-GCK TAPFSDVANQLVVDVADHIRHGLMSNPRAVVEPLVVGNATRYLAASMLAA
TH_3937|M.thermoresistible__bu LRPAVGAT-RLWQDTVRYVRDHVLVD-DTRATPLVVGQAARLLAAVTASA
Mb1966c|M.bovis_AF2122/97 HAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPDGCPLARPVSAPTRWA
Rv1931c|M.tuberculosis_H37Rv HAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPDGCPLARPVSAPTRWA
MMAR_2855|M.marinum_M KVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPGGQ-TQFA
MUL_2902|M.ulcerans_Agy99 KVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPCGQ-TQFA
MAV_4063|M.avium_104 WRPRSRAAVRAWHRALDYAMLTLASP-DTARQPLIAAGMAGLLAGALLEC
MAB_2899c|M.abscessus_ATCC_199 QVLTSAGAAAGLDLCLHIVARDHGAAVAAEAARVAVAPLHRDGGQAQYVI
MSMEG_2260|M.smegmatis_MC2_155 EFDLTTEAATRWHAAVQLIHTEVYHAGSLVQRGCAIGPVEELAMSSLLYL
.
Mvan_0336|M.vanbaalenii_PYR-1 FP-NTAAAPP--RVQDSSPRLLERALAFIDDNADKDISLGDIAAAARVTP
Mflv_3472|M.gilvum_PYR-GCK FP-HTGADRP--PGETDNYDALRRGTAFIDDNAHRDISPADVAHAARVSG
TH_3937|M.thermoresistible__bu FP-NSAAEPAGQTVNGQRPPLLRRALDYIDANAAADISLADIAAAVHVTP
Mb1966c|M.bovis_AF2122/97 DP-VRGSGVDATRQTDLDP----PGAGGHRGRAGGAHRIGELAQRAAMSP
Rv1931c|M.tuberculosis_H37Rv DP-VRGSGVDATRQTDLDP----PGAGGHRGRAGGAHRIGELAQRAAMSP
MMAR_2855|M.marinum_M AP-VWMP--RAKRPSIRDV----QEA--IEAQPGGPHSIEELAHRAAMSP
MUL_2902|M.ulcerans_Agy99 AP-VWMP--RAKRPSIRDV----QEA--IEAQPGGPHSIEELAHRAAMSP
MAV_4063|M.avium_104 YP-SNLTEQD-PVSDLALPETLKEAVSFIHRHAAEDIGINDVAAAVHLTP
MAB_2899c|M.abscessus_ATCC_199 RN-RRRAEVS-----------LGEILAWIEHNAHRELSLEDLATEASTSV
MSMEG_2260|M.smegmatis_MC2_155 QPSTYYSDITRPTPATPRRAVIQQAVDYIEDHLAEKITMESLAEALHMSV
. . .:* :
Mvan_0336|M.vanbaalenii_PYR-1 QSVAAMFRRHLSCTPKEYLRKVRLDHAHRDLIANNPA-TATVADIAARWG
Mflv_3472|M.gilvum_PYR-GCK PTLKELFVRHRNCTPLQRLQRVRLEHVHRELAMADPQ-TSTVADIARKWG
TH_3937|M.thermoresistible__bu RALQYMFRRHLQTTPLQYLRRIRLHRAHHDLLAQTPA-SDTVGAIAARWG
Mb1966c|M.bovis_AF2122/97 RHFTRVFSDEVGEAPGRYVERIRTEAARRQLEET----HDTVVAIAARCG
Rv1931c|M.tuberculosis_H37Rv RHFTRVFSDEVGEAPGRYVERIRTEAARRQLEET----HDTVVAIAARCG
MMAR_2855|M.marinum_M RHFTRVFTGEVGEAPRQYVERVRTEAARRQLEET----EDTVVAIAARCG
MUL_2902|M.ulcerans_Agy99 RHFTRVFTGEVGEAPGRYVERVRTEAARRQLEET----EDTVVAIAARCG
MAV_4063|M.avium_104 RAVQYLFRRQLDTTPTEYMRRVRLSRAHQELVAATTA-SSTVTEIAQRWG
MAB_2899c|M.abscessus_ATCC_199 RSLNRRFRAETGQTPMQWLTGVRVRHAQQLLERS----ADSVEWIGREVG
MSMEG_2260|M.smegmatis_MC2_155 RSIQQGFRTELGMSPTTFIRERRLERVREELTDAIPSDGVTVTAVAERWG
. * . :* : * .:. * :* :. . *
Mvan_0336|M.vanbaalenii_PYR-1 FGVVEAFAVYYRGRYGVHPETTLAS------
Mflv_3472|M.gilvum_PYR-GCK FWRLGPFTTVYRETYGQVPDRTLDQ------
TH_3937|M.thermoresistible__bu FAHAGRFAMQYRQTYGRSPHQTLRG------
Mb1966c|M.bovis_AF2122/97 FGTAETMRRSFIRRVGISPDQYRKAFA----
Rv1931c|M.tuberculosis_H37Rv FGTAETMRRSFIRRVGISPDQYRKAFA----
MMAR_2855|M.marinum_M FGTAETMRRNFIRRVGISPDQYRKAFA----
MUL_2902|M.ulcerans_Agy99 FGTAETMRRNFIRRVGISPDQYRKAFA----
MAV_4063|M.avium_104 FAHTGRFAVLYRQTYGQSPHTTLRQQTAV--
MAB_2899c|M.abscessus_ATCC_199 FGSPANFREQFRRLTGVSPLAYRNTFRAQSA
MSMEG_2260|M.smegmatis_MC2_155 FHHLGSFAVEYRKRWGETPSETLRR------
* : : * *