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SRLTRLGFIDIRRTSDPVRRKVRSRGVPPALADHEIFYTEDVREAARLVGRTLSPLTLTVDAADAGGFAA TMHGVRLRNVSLLYLDLHVAATLDIPESGRYFAVHMPLNGSATVTHPAAEFDAGTTRSLVTSPGDPVRMS FAHDSPQMLVRIEEEAMNAHLTRLLGRNLVGPLKFEPEFDLTTEAATRWHAAVQLIHTEVYHAGSLVQRG CAIGPVEELAMSSLLYLQPSTYYSDITRPTPATPRRAVIQQAVDYIEDHLAEKITMESLAEALHMSVRSI QQGFRTELGMSPTTFIRERRLERVREELTDAIPSDGVTVTAVAERWGFHHLGSFAVEYRKRWGETPSETL RR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2260 | - | - | 100% (353) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6546 | - | 8e-09 | 32.48% (117) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_5193 | - | 2e-08 | 28.81% (177) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 3e-05 | 29.20% (113) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0534 | - | 9e-36 | 30.91% (317) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv3833 | - | 3e-05 | 29.20% (113) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1313 | - | 2e-08 | 26.71% (146) | AraC family transcriptional regulator |
| M. marinum M | MMAR_4426 | - | 9e-13 | 25.96% (312) | transcriptional regulatory protein |
| M. avium 104 | MAV_4063 | - | 2e-20 | 34.50% (171) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_1032 | - | 1e-152 | 74.58% (354) | putative transcriptional regulator |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2363 | - | 1e-149 | 76.69% (326) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2260|M.smegmatis_MC2_155 -------MSRLTRLGFIDIRRTSDPVRRKVRSRGVPPAL----------A
Mvan_2363|M.vanbaalenii_PYR-1 ----------------------------------MPPAL----------T
TH_1032|M.thermoresistible__bu -------MSRLTRLGFIDVRRTSNPVRRKVRSRGVPPSL----------V
Mb3863|M.bovis_AF2122/97 --------------------------------------------------
Rv3833|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0534|M.gilvum_PYR-GCK MTQDPESEARPSALVFDGATDSVGELRLPQRESELLPMANGPKMAGSYFS
MAV_4063|M.avium_104 ----MGLTTMTVRDDGAPVGAPAEAARSDYGPVDPVLAVNGERRARPVAV
MAB_1313|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4426|M.marinum_M ------------MTSAEQVAAKPGMARRRVGGIMVNPSRPGQRCAATSAR
MSMEG_2260|M.smegmatis_MC2_155 DHEIFYTEDVREAARLVGRTLSPLTLTVDAADAGGFAATMHGVRLRNVSL
Mvan_2363|M.vanbaalenii_PYR-1 EHEIFYTEDISKATRLIGRALSPLTLTVDPADADGFAATMHGIRLRNVSM
TH_1032|M.thermoresistible__bu DNEIFYTEDVAEAARLTGQVLAPLTLTVGAPDSAGFAATAHGVRLRNVSM
Mb3863|M.bovis_AF2122/97 ---------------------------------------MSENSHHRLAT
Rv3833|M.tuberculosis_H37Rv ---------------------------------------MSENSHHRLAT
Mflv_0534|M.gilvum_PYR-GCK RRETVCTEQLSAAEHLASEIFTPHRLRYSRRGQR-LNARLSAARIGAVTV
MAV_4063|M.avium_104 EYKQFRGADAQSARRFFATAYDPGWRIAGVTNHCVVSHRRSD--TGSMTV
MAB_1313|M.abscessus_ATCC_1997 ----------------------------------MVFGGFGGVALGELQI
MMAR_4426|M.marinum_M RNERFEAFQHAISQTFVP--LALCVDDVGTFRGQVRSASLGTVQLSDVRV
:
MSMEG_2260|M.smegmatis_MC2_155 L-YLDLHVAATLDIPESGRYFAVHMPLNGSATVTHPAAEFDAGTTRSLVT
Mvan_2363|M.vanbaalenii_PYR-1 L-YLDLHVPASIDIPESGRYYAVHMPMNGVAMVHHPSSTFQASTLRSLVS
TH_1032|M.thermoresistible__bu L-YLDLHVPCALDIPRLGAYFAVHMPLNGSAEVHHRGRQFQITPVRSLVT
Mb3863|M.bovis_AF2122/97 T-SLTLPPGARIERHR-HPSHQIVYPSAGAVSVTTHAGTWITPVNRAIWI
Rv3833|M.tuberculosis_H37Rv T-SLTLPPGARIERHR-HPSHQIVYPSAGAVSVTTHAGTWITPVNRAIWI
Mflv_0534|M.gilvum_PYR-GCK G-YLRYGADVELVNSTALDDYHINVPLTSHADSWCGPATAQATPTQAAVF
MAV_4063|M.avium_104 D-EVAIQGRMTLEIPA-GDTVVVIQPRAGALNVAGGP---LATPDFPLLV
MAB_1313|M.abscessus_ATCC_1997 T-FVSEPIVEPTEWYFDEPHHVVAVYQGG--RILSKEIDFVDGLSRRYLP
MMAR_4426|M.marinum_M GNDVLVRRTAKLINHSAPDYLKVAMPLNGKCVVTQDGHEETLAPRDFAVY
: : .
MSMEG_2260|M.smegmatis_MC2_155 SPGDPVRMSFAHDSPQMLVRIEEEAMNAHLTRLLGRNLVGPLKFEPEFDL
Mvan_2363|M.vanbaalenii_PYR-1 SPGVPLRIDLGVDTPQLLIRIEQQAMTAHVTRLIGRNLARPLVFEPEFDL
TH_1032|M.thermoresistible__bu SPRGPLRIAFEHDSPQLVIRIEEAAMAAHLTRLLGRRLRRPLEFDPEFDM
Mb3863|M.bovis_AF2122/97 PAG-----------------------CWHQHKFHGHTQFHGVALDPQR-Y
Rv3833|M.tuberculosis_H37Rv PAG-----------------------CWHQHKFHGHTQFHGVALDPQR-Y
Mflv_0534|M.gilvum_PYR-GCK LPGRPAGIKWAADCGQLCVKFSRTDLEYELEGLLGRPAVRPLNITHSMDL
MAV_4063|M.avium_104 AHG--MACVLHCHGARFDVVTIAAEVLQKVAAEWHTALSQQTQFLNWRPR
MAB_1313|M.abscessus_ATCC_1997 KVG--------------DVLVVPMGSRAAITTQGERASFCRFDIPTRLLD
MMAR_4426|M.marinum_M DTTR-------------PYSLAFSGAYRALVIMFPRDQVRLSSAELTRLT
MSMEG_2260|M.smegmatis_MC2_155 TTEAATRWHAAVQLIHTEVYHAGSLVQRGCAIGPVEELAMSSLLYLQPST
Mvan_2363|M.vanbaalenii_PYR-1 ATEAAMRWNAAVQLVHTEVYHAGSLIQKGRAIGPVEELVMSSLLHLQPSN
TH_1032|M.thermoresistible__bu TTEAAMRWHTAVQLIHTEVFHPGSLVQRGQGIGPVEELVMSSLLQLQPST
Mb3863|M.bovis_AF2122/97 RGGPATPTVLAVNPLMRELIIACSQADR---TDTDEHHRMLAVLQDQLP-
Rv3833|M.tuberculosis_H37Rv RGGPATPTVLAVNPLMRELVIACSQADR---TDTDEHHRMLAVLQDQLP-
Mflv_0534|M.gilvum_PYR-GCK TADSSRAWLALLSVLYREVSRPESIVQHPMTGRHFEQLVMHGFLHAQPH-
MAV_4063|M.avium_104 SRAAVRAWHRALDYAMLTLASP-DTARQPLIAAGMAGLLAGALLECYPS-
MAB_1313|M.abscessus_ATCC_1997 QRDLQPRVAYSDPLILQLASRMYSVADRTDVIARLLRESLADVVRLHLSD
MMAR_4426|M.marinum_M ARRLNGRDGLGAPVSAFLAEMGNRLDDANTAGTLYLADAVLDMLAASFAA
.:
MSMEG_2260|M.smegmatis_MC2_155 YYSDITRPTP-ATPRRAVIQQ-AVDYIEDHLAEK-ITMESLAEALHMSVR
Mvan_2363|M.vanbaalenii_PYR-1 YHADITQPSP-PDPRRTVIQQ-AMDFIDDHLAER-ITMDSLAAAVHMSVR
TH_1032|M.thermoresistible__bu YYDELLRPPPQPGQRRAVVRA-AMNYIEEHLAER-ITVESVAKAVHVSVR
Mb3863|M.bovis_AF2122/97 -TTSIREPLWVPSPTDRRLRH-ACALIADNLTQP-LTLQQIGGRIGVSQR
Rv3833|M.tuberculosis_H37Rv -TTSIREPLWVPSPTDRRLRH-ACALIADNLTQP-LTLQQIGGRIGVSQR
Mflv_0534|M.gilvum_PYR-GCK YQAMALAADQHAAPPPKVLRT-ALDLIEEHPERS-WTTTDLAREVGISAR
MAV_4063|M.avium_104 --NLTEQDPVSDLALPETLKE-AVSFIHRHAAED-IGINDVAAAVHLTPR
MAB_1313|M.abscessus_ATCC_1997 HYAALRPRPERRRLLDSAMQARVTEYIEDGLDAD-ISLSALAGHAQMSTS
MMAR_4426|M.marinum_M QLSDETGGNAARGTRGLALRI--RAFIESRLGDPGLDVSTIAAAHHVSVR
:: * :. ::
MSMEG_2260|M.smegmatis_MC2_155 SIQQGFRTELGMSPTTFIRERRLERVREELTDAIPSDGVTVTAVAERWGF
Mvan_2363|M.vanbaalenii_PYR-1 SIQQGFRSELGMSPMAFVRERRLERVHEELADAIPSDGVTVTAVAERWGF
TH_1032|M.thermoresistible__bu SIQQNFRDELGLTPMEFVRERRLQRVHEELTDAIPSDGVTVTAVAQRWGF
Mb3863|M.bovis_AF2122/97 TLSRLFSDELGMTFPQWRTQLRLQHALVLLAERH-----DVTSVASECGW
Rv3833|M.tuberculosis_H37Rv TLSRLFSDELGMTFPQWRTQLRLQHALVLLAERH-----DVTSVASECGW
Mflv_0534|M.gilvum_PYR-GCK ALQESFKRHVGLPPLTYLREVRLIRAHAELAASSES-AVTVARVAMKWGF
MAV_4063|M.avium_104 AVQYLFRRQLDTTPTEYMRRVRLSRAHQELVAATTASS-TVTEIAQRWGF
MAB_1313|M.abscessus_ATCC_1997 EFRKAFTEVFGHTPYQFVLDRRMSRAKQLLATTDLS----VTDISVAVGF
MMAR_4426|M.marinum_M YLQKLFESQ-GQTVTGWIRDRRIEHCRRDLEDHRLA-EVPVSSIAARWGL
. * . . : *: : * *: :: *
MSMEG_2260|M.smegmatis_MC2_155 HHLGSFAVEYRKRWGETPSETLRR----------------
Mvan_2363|M.vanbaalenii_PYR-1 HHLGSFAVEYRKRWGEAPSETLRR----------------
TH_1032|M.thermoresistible__bu QHLGSFAVEYRKRWGETPSETLRR----------------
Mb3863|M.bovis_AF2122/97 ATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Rv3833|M.tuberculosis_H37Rv ATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Mflv_0534|M.gilvum_PYR-GCK GHLGRFSAEYRRKFGVTPQHTLRAA---------------
MAV_4063|M.avium_104 AHTGRFAVLYRQTYGQSPHTTLRQQTAV------------
MAB_1313|M.abscessus_ATCC_1997 SSPSHFATTFKTRIGVTPTAYRSGV---------------
MMAR_4426|M.marinum_M VNASHFSRLFKAVHGSSPAEYRAQVSLRSPSASTDRG---
. * :: * :*