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VLTATVEARNRRVPERTGEFSPRLAALGRFTLRHKALVIGAWLGVAVILAVVFPQLETVVRQQSVQLLPN DVASFIAVEEMAAAFDEHGAKTSIVVAMEDPAGLTPQTRQRYDALVAALRADATNVLLVQDFLSDPTTRS QVVSEDGKAWFLPVGIVGTLGDPQAAASVEAVRASADSAFAGSSSTVHVTGPAATFHDQIATAEHDALLV KVASAALIAIILLLVYRSVVTALLPLLVVGVSVAVARGVLSGLGEAGMPVSQFTVIFLVGILLGAGTDYS VFFISRYHEQRRLGTDPEEAIIYACGSIGRVILASAATVALALASMVFARLSVFQGVGPACAIAVLIGFL ATVTLLPPVMALAAKRGIAEPRADLSRRYWNRIAVTVVRRPKPLLAGSLVVLLALTGVAATMTISYDDRQ GQPAATDSNQGYKLLDRHFAKDSVITQFLLVQSDTDMRTAKALADLDQLASRIAQMPGITRVSGVTRPTG DRLEQAQLSWQNGQIGDKMAGAVAEGRAREHDLTKLTDGADQLAAGLAQLDTTLRRALTPLSGLLSQVQD TGRQLQNARPVIEQLNTTAPTVDQALRSGPGLRPLATQASAAIAAVEPLIAGLNASPWCATTPQCAQLRD QTGILVTLRRGGFFDQVADLGDHLGPDTTLSGTLASLQTAVTTMQQALGVTGDPADLAGNMRRLQDGVSQ LASGGRALASGVHALADSNIQMLGGMSQIAAQLQNSARDTAGSDAAAGFYLPPDSFENRQFSDVARQFVS ADGRTARFAITSSHDPFSAEAMELNGRIIDTANAATPNTSLAGTSISIVGFPALNSDLQQLLSTDFARLG AATLLVVGIVLVLLLRAIVAPLYLLGTVVLNYAAALGIGVLVFQYGFGQAIAWPVPLLAFILLVAVGADY NMLLISRLREESGRSVRVGVLRTVASTGSVITSAGIIFAVSMFGLMTGSVHIMVQAGFIIGCGLLLDTFV VRTLTVPAIATLLREKSWWPQR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2900 | - | - | 100% (1003) | MMPL domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0312 | - | 0.0 | 69.63% (991) | MMPL domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0271 | - | 0.0 | 41.75% (982) | transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3853c | mmpL8 | 0.0 | 40.18% (1018) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_4632 | - | 0.0 | 68.02% (566) | MMPL domain-containing protein |
| M. tuberculosis H37Rv | Rv3823c | mmpL8 | 0.0 | 39.98% (1018) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_01231 | mmpL10 | 0.0 | 39.39% (980) | hypothetical protein MLBr_01231 |
| M. abscessus ATCC 19977 | MAB_0855 | - | 0.0 | 40.46% (996) | MmpL family protein |
| M. marinum M | MMAR_4836 | - | 0.0 | 68.36% (1002) | MmpL family transport protein |
| M. avium 104 | MAV_1761 | - | 0.0 | 40.87% (986) | MmpL10 protein |
| M. smegmatis MC2 155 | MSMEG_4741 | - | 0.0 | 40.18% (988) | MmpL protein |
| M. thermoresistible (build 8) | TH_3450 | - | 0.0 | 70.94% (967) | PUTATIVE MMPL domain protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 1e-120 | 30.63% (973) | transmembrane transport protein, MmpL5 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4836|M.marinum_M MADYGWVSSGVATLSRPVRERLQKVAAGEGAYSDRLARLAGFSIR-HKVL
TH_3450|M.thermoresistible__bu ------------------------------------------------VL
Mflv_4632|M.gilvum_PYR-GCK -MTDGSADAPSQAKRPGRRANGSTDPADTREYSERLATLARFTLR-HKAL
Mvan_2900|M.vanbaalenii_PYR-1 -----------MVLTATVEARNRRVPERTGEFSPRLAALGRFTLR-HKAL
MLBr_01231|M.leprae_Br4923 -------------------------------------------------M
MAV_1761|M.avium_104 -----------------------MSPTAPAGDEVEMRRIADFVVR-WPWL
Mb3853c|M.bovis_AF2122/97 ----MCDVLMQPVRTPRPSTNLRSKPLRPTGDGGVFPRLGRLIVR-RPWV
Rv3823c|M.tuberculosis_H37Rv ----MCDVLMQPVRTPRPSTNLRSKPLRPTGDGGVFPRLGRLIVR-RPWV
MAB_0855|M.abscessus_ATCC_1997 ----------------------------MAENTGGIYGLIAQIVRRAPVI
MSMEG_4741|M.smegmatis_MC2_155 ------------------------------MSRVGFSGLGRFIVR-HPLV
MUL_0757|M.ulcerans_Agy99 ----------------MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVP
MMAR_4836|M.marinum_M IIGMWVVTAAALAVLFPQLETVVRQQSVNLIPRDAPSLQTVDRMGAAFGE
TH_3450|M.thermoresistible__bu VIGTWLAVAVVLALLFPQLETVVRQQSVDLIPRDVPSFQTLDRMSAAFGE
Mflv_4632|M.gilvum_PYR-GCK VIGVWLGAAVVLALLFPQLETVVRQQSVDLIPRDAPSLQTVDRMSAAFGE
Mvan_2900|M.vanbaalenii_PYR-1 VIGAWLGVAVILAVVFPQLETVVRQQSVQLLPNDVASFIAVEEMAAAFDE
MLBr_01231|M.leprae_Br4923 VIGCWTLLALMLPMTVPSLTELTQRHPVVILPVDAPSSVAAKKISQAFHE
MAV_1761|M.avium_104 VIGFWAALAVALPLAFPSLAEMAQKHPLAILPGNAPSNVAARQMTEAFHE
Mb3853c|M.bovis_AF2122/97 VIAFWVALAGLLAPTVPSLDAISQRHPVAILPSDAPVLVSTRQMTAAFRE
Rv3823c|M.tuberculosis_H37Rv VIAFWVALAGLLAPTVPSLDAISQRHPVAILPSDAPVLVSTRQMTAAFRE
MAB_0855|M.abscessus_ATCC_1997 VIGLWIGLAAVLALTAPSLQKAIEDHPVDLLPKDAPVMETTRQMVESFQE
MSMEG_4741|M.smegmatis_MC2_155 VIASWLAVAGVLLAAVPSLPAVAERNPPGFLPADSEVFAAGNAMQEAFNE
MUL_0757|M.ulcerans_Agy99 LILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFRE
:* * * *.* . :. : * : : * *
MMAR_4836|M.marinum_M QGSKTTIFVAMEDPAGLTAPVRQRYNTMISRLRADSEHVRLVQDLLADPV
TH_3450|M.thermoresistible__bu QGSKTTVFVAMEDPAGLTPAARDRYEAMVSRLRADTDHVLLVQDLLADPV
Mflv_4632|M.gilvum_PYR-GCK EGSKTMVFVAMEDPTGLTPTARQRYGELVRRLQAEGDHVLLVQDLLADPI
Mvan_2900|M.vanbaalenii_PYR-1 HGAKTSIVVAMEDPAGLTPQTRQRYDALVAALRADATNVLLVQDFLSDPT
MLBr_01231|M.leprae_Br4923 VDSENVLIVLLTDDKGLGPADETVYRTLVDRLRNDTKDVVVLQDFLSTPP
MAV_1761|M.avium_104 SGSDDLLLVALTDEKGLGPADEAVYRRLVDALRRDTRDVVMVQDFISAPP
Mb3853c|M.bovis_AF2122/97 AGLQSVAVVVLSDAKGLGAADERSYKELVDALRRDTRDVVMLQDFVTTPP
Rv3823c|M.tuberculosis_H37Rv AGLQSVAVVVLSDAKGLGAADERSYKELVDALRRDTRDVVMLQDFVTTPP
MAB_0855|M.abscessus_ATCC_1997 SGAQNILLIVLTNENGLTPADEQTYRILAARMREDTRDVSMVQDFITKPP
MSMEG_4741|M.smegmatis_MC2_155 TGGGNVAIAILSNENGLTPADEETYRALVDKLRADTEYVLSTQDFVTIPE
MUL_0757|M.ulcerans_Agy99 GDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPL
. . : . * . . * : :: : * **: *
MMAR_4836|M.marinum_M TASQAVSQDGKAWYVPVGVAGTLGDVKAAESVQAVRTIAAQAFSGS----
TH_3450|M.thermoresistible__bu TATQAVSQDGKAWYLPVGVAGTLGDPTAAESVQAVRALAAEAFADS----
Mflv_4632|M.gilvum_PYR-GCK TEAQAVSADRKAWYLPVGVTGTLGDPTAAESLNAVRDIAAEVFTGS----
Mvan_2900|M.vanbaalenii_PYR-1 TRSQVVSEDGKAWFLPVGIVGTLGDPQAAASVEAVRASADSAFAGS----
MLBr_01231|M.leprae_Br4923 LHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAGIVKQTLEST----
MAV_1761|M.avium_104 LRSAVTSKDRKAWVLPVGIAGELGTPQSYAAFNRIAGIVKQTLEKHENGP
Mb3853c|M.bovis_AF2122/97 LRELMTSKDNQAWILPVGLPGDLGSTQSKQAYARVADIVEHQVAGS----
Rv3823c|M.tuberculosis_H37Rv LRELMTSKDNQAWILPVGLPGDLGSTQSKQAYARVADIVEHQVAGS----
MAB_0855|M.abscessus_ATCC_1997 LREMMSSTDGKAWYLPVGLQGELATPESGKAYVGALKIIKDATQGT----
MSMEG_4741|M.smegmatis_MC2_155 LRQVMTSEDNKAWQLPISAAGTMGTAEGQNAYRQIVDTVKSSTANT----
MUL_0757|M.ulcerans_Agy99 TATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQAPP----
* * :* : : * . . :
MMAR_4836|M.marinum_M ---PTNVRVTGPPATFHDQIASAEEDLVVISIATAGLIAMILLVVYRSVF
TH_3450|M.thermoresistible__bu ---STTVRVTGPPATFSDQIGSAEHDLVLISIATAGLIALILLIVYRSVF
Mflv_4632|M.gilvum_PYR-GCK ---TTTVQVTGPPATFSDMIASAEHDLLLISIATAGVIALILLIVYRSVF
Mvan_2900|M.vanbaalenii_PYR-1 ---SSTVHVTGPAATFHDQIATAEHDALLVKVASAALIAIILLLVYRSVV
MLBr_01231|M.leprae_Br4923 AGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILMIIYRNPI
MAV_1761|M.avium_104 AATSLTVSLTGPAATVADLTVAGERDRLPIELAIAVLVLVVLLVVYRSAV
Mb3853c|M.bovis_AF2122/97 ---TLTANLTGPAATVADLNLTGQRDRSRIEFAITILLLVILLIIYRNPI
Rv3823c|M.tuberculosis_H37Rv ---TLTANLTGPAATVADLNLTGQRDRSRIEFAITILLLVILLIIYGNPI
MAB_0855|M.abscessus_ATCC_1997 ---SLKAFTTGPTATVGDLTVVGERDLHKVEITTAALVLLILLIVYRNPV
MSMEG_4741|M.smegmatis_MC2_155 ---SLSAEVIGPAATFEDVVKIGERDQHVIEIATVLIVLMILIIVYRNLV
MUL_0757|M.ulcerans_Agy99 ---GVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSII
.. *..: . * . .. :... :: :*:::* . .
MMAR_4836|M.marinum_M TALLPLLVIGVSLAVGRGVLSALGESGMP-VSQFTIAFMTVILLGAGTDY
TH_3450|M.thermoresistible__bu TALLPLLVIGVSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
Mflv_4632|M.gilvum_PYR-GCK TALLPLLVIGLSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
Mvan_2900|M.vanbaalenii_PYR-1 TALLPLLVVGVSVAVARGVLSGLGEAGMP-VSQFTVIFLVGILLGAGTDY
MLBr_01231|M.leprae_Br4923 TMLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMIAGAGTDY
MAV_1761|M.avium_104 TMLLPLVTILLSLVIAQAAVAGYSQLTGSGVSNQSIVFLSAIMAGAGTDY
Mb3853c|M.bovis_AF2122/97 TMVLPLITIGMSVVVAQRLVA-IAGLAGLGIANQSIIFMSGMMVGAGTDY
Rv3823c|M.tuberculosis_H37Rv TMVLPLITIGMSVVVAQRLVA-IAGLAGLGIANQSIIFMSGMMVGAGTDY
MAB_0855|M.abscessus_ATCC_1997 TMMLPLIVVGVSLGIAQAAVGGLAQMGLS-ISNQTLTFMTAMMMGAGVDY
MSMEG_4741|M.smegmatis_MC2_155 AMLLPLLMIGMALVVAEQSVAGLGAIHLIGLGPQTLMLMTAMMMGAGTDY
MUL_0757|M.ulcerans_Agy99 TAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDY
: : * : .: . :. . :. :: : .*..**
MMAR_4836|M.marinum_M SVFLISRYHEQRRQN----VPPDLSVINATATIGRVILASAATVAFAFLA
TH_3450|M.thermoresistible__bu TVFLISRYHEQRRAQ----VAPEQAAIYATASIGRVILASAATVAFAFLA
Mflv_4632|M.gilvum_PYR-GCK TVFLISRYHEQRRAQ----VPADQAIIHATASIGRVILASAATVALAFLA
Mvan_2900|M.vanbaalenii_PYR-1 SVFFISRYHEQRRLG----TDPEEAIIYACGSIGRVILASAATVALALAS
MLBr_01231|M.leprae_Br4923 AVFLISRYHDYIRMGSGSAQDAGCAVRQALISLGKVIAASAATVGITFLG
MAV_1761|M.avium_104 AVFLISRYHDFLRRG----DDFDQAVRKALISIGKVITASASTVGITFLL
Mb3853c|M.bovis_AF2122/97 AVFLISRYHDYLRQG----ADSDQAVKKALTSIGKVIAASAATVAITFLG
Rv3823c|M.tuberculosis_H37Rv AVFLISRYHDYLRQG----ADSDQAVKKALTSIGKVIAASAATVAITFLG
MAB_0855|M.abscessus_ATCC_1997 AVFLISRYHEYIKQG----LASDDAVAAALESIGKVVAASAATVAVTFLG
MSMEG_4741|M.smegmatis_MC2_155 AIFLFSRYHECVRSG----LSSDDAVVEALDSIGKVIAGSAGTVAITFMG
MUL_0757|M.ulcerans_Agy99 AIFLIGRYQEARGLG----QDRESAYYTMFGGTAHVVLGSGLTIAGATFC
::*::.**:: : .:*: .*. *:. :
MMAR_4836|M.marinum_M MVFAKLSVFAALGPACAIAVFVGFAATVTLFPPVLALAAKRG-IGEPKAD
TH_3450|M.thermoresistible__bu MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLALAAKRG-IGDPKPD
Mflv_4632|M.gilvum_PYR-GCK MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLSLAAKRG-IGEPKPD
Mvan_2900|M.vanbaalenii_PYR-1 MVFARLSVFQGVGPACAIAVLIGFLATVTLLPPVMALAAKRG-IAEPRAD
MLBr_01231|M.leprae_Br4923 MSFTKIRVFSTVGPALAIGIAVAFLAAVTLMPALLVLAGTRG-WVAPRRD
MAV_1761|M.avium_104 IGFARMGVFKTVGISSAIGIGVAFLAAVTLLPAIMVLAGPRG-WIRPRRE
Mb3853c|M.bovis_AF2122/97 MVFTQLGILKTVGPMLGISVAVVFFAAVTLLPALMVLTGRRG-WIAPRRD
Rv3823c|M.tuberculosis_H37Rv MVFTQLGILKTVGPMLGISVAVVFFAAVTLLPALMVLTGRRG-WIAPRRD
MAB_0855|M.abscessus_ATCC_1997 MGFTKLGILSTVGPALSVSILIAFVASVTFLPAVLVLVGRRG-WITPRKA
MSMEG_4741|M.smegmatis_MC2_155 LAFTDLGVFSTVGPALSVTIGFGFVASVTLLPAMVVLAGRRG-WVKPRKD
MUL_0757|M.ulcerans_Agy99 LSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRM
: *: : : :* .: : . . :::*: *.:: : . * *:
MMAR_4836|M.marinum_M RTRRYWNWIAVAVVRRPVPLLVASLALVLGLAAVALTMHISYDDRRGQPA
TH_3450|M.thermoresistible__bu RTRRYWNSVAVAVVRRPVTLLTISLAVLLALSAVAVTINISYDDRKGQPA
Mflv_4632|M.gilvum_PYR-GCK RTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAATIKISYDDRKGQPD
Mvan_2900|M.vanbaalenii_PYR-1 LSRRYWNRIAVTVVRRPKPLLAGSLVVLLALTGVAATMTISYDDRQGQPA
MLBr_01231|M.leprae_Br4923 RAGAFWRRTGVRIVRRPVAYLSASMVILIVLALCASLVRFNYDDRKQIPA
MAV_1761|M.avium_104 LTTGLWRRSGIRIVRRPRAHLVASVLVLIILASCAGLVRYNYDDRKALRP
Mb3853c|M.bovis_AF2122/97 LTRRFWRSSGVHIVRRPKTHLLASALVLVILAGCAGLARYNYDDRKTLPA
Rv3823c|M.tuberculosis_H37Rv LTRRFWRSSGVHIVRRPKTHLLASALVLVILAGCAGLARYNYDDRKTLPA
MAB_0855|M.abscessus_ATCC_1997 YANKIWHRSGINIVKRPGAHLAVSLVVLVILATCGAMVKFGYDDRKNLPP
MSMEG_4741|M.smegmatis_MC2_155 LTGRIWRRSGVHIVRKPVIHLVASLTVLLALAGCAMLVNFNYDDRKNLPD
MUL_0757|M.ulcerans_Agy99 ARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPA
*. . :*: * * : : : .*:**.
MMAR_4836|M.marinum_M TTASNEGYRLLDRHFRKDAIVTEFMVVESPTDMRTSKALADLDEMASRVS
TH_3450|M.thermoresistible__bu DTASNQGYQLLDRHFRKDVVFTEFLVVENPTDMRTGKGLADLDEMASRVA
Mflv_4632|M.gilvum_PYR-GCK TTASNQGYHLLDRHFRKDVVISEFLVVENPTDMRTGKGLADLDEMASRVS
Mvan_2900|M.vanbaalenii_PYR-1 ATDSNQGYKLLDRHFAKDSVITQFLLVQSDTDMRTAKALADLDQLASRIA
MLBr_01231|M.leprae_Br4923 SDESSVGYAALESHFPVGQAIPEYLLIQSPHDLRTPRALADMAELAQRVS
MAV_1761|M.avium_104 SAPSSVGYAALERHFPVNQSIPEYILIRSPHDLRTPQALADLEQLADRVS
Mb3853c|M.bovis_AF2122/97 SVESSIGYAALDKHFPSNLIIPEYLFIQSSTDLRTPKALADLEQMVQRVS
Rv3823c|M.tuberculosis_H37Rv SVESSIGYAALDKHFPSNLIIPEYLFIQSSTDLRTPKALADLEQMVQRVS
MAB_0855|M.abscessus_ATCC_1997 WADSNQGYAAIEKHFPVNSTLPQYLYIKSPHDLRTPRGLADLEQMAARVS
MSMEG_4741|M.smegmatis_MC2_155 DAHSNMGYAALDKHFPVSSTVQQFILIQSPHDLRSPKALADMEQMAQRVS
MUL_0757|M.ulcerans_Agy99 DLPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIF
:. ** : ** : : :.. *:*. : : ::. :
MMAR_4836|M.marinum_M QLPGVTKVSGVTRPTGARLDQAQLSWQNGEIGDKMAGAVAKGDAHKDDLA
TH_3450|M.thermoresistible__bu QIPGVTKVSGVTRPTGERLDQAKLAWQNQQIGDKMADAVADGNARKADLA
Mflv_4632|M.gilvum_PYR-GCK QIPGVTKVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDLA
Mvan_2900|M.vanbaalenii_PYR-1 QMPGITRVSGVTRPTGDRLEQAQLSWQNGQIGDKMAGAVAEGRAREHDLT
MLBr_01231|M.leprae_Br4923 QIPGIALVRGVTRPTGKPLEETSATYQAGMVGKQLGSASHLIGESTGDLN
MAV_1761|M.avium_104 QLPNVSVVSGITRPTGNVPEQFRATYQAGAIGSMLAGGSTMINDQTDDLN
Mb3853c|M.bovis_AF2122/97 QVPGVAMVRGITRPAGRSLEQARTSWQAGEVGSKLDEGSKQIAAHTGDID
Rv3823c|M.tuberculosis_H37Rv QVPGVAMVRGITRPAGRSLEQARTSWQAGEVGSKLDEGSKQIAVHTGDID
MAB_0855|M.abscessus_ATCC_1997 QVPGVDKVRGITRPTGEPLEEAKLSYQAGEVGGKLGDASNLIDARTRDLD
MSMEG_4741|M.smegmatis_MC2_155 QLPDIEMVRGVTRPTGEMLQEARATWQAGEVGGKLNDASTLIDANDANLS
MUL_0757|M.ulcerans_Agy99 GVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSML
: .: * .:*** * :. .: * .:
MMAR_4836|M.marinum_M KLTHGADQLAGGLAQLDTTLRTALTPLTGLLTQAQSSGSQVQRFRPLLQQ
TH_3450|M.thermoresistible__bu KLTNGADQLAAGLAQLDTTLRTALAPLSGILSQAQSAGTQMQQFRPLLQQ
Mflv_4632|M.gilvum_PYR-GCK KLTGGADQLADGLAQLDSTVRTALTPLAGILTQAQSAGTQVNQFRPGLLR
Mvan_2900|M.vanbaalenii_PYR-1 KLTDGADQLAAGLAQLDTTLRRALTPLSGLLSQVQDTGRQLQNARPVIEQ
MLBr_01231|M.leprae_Br4923 RLASGAGLLADKLGDVRIQVGQAVAGISGLLDNLAFAQKMFGDSK-TLGE
MAV_1761|M.avium_104 RLARGAGTLADNLGDVRGQVNQLAASVRELENAFSSTKNQYSGDA-LVNQ
Mb3853c|M.bovis_AF2122/97 KLAGGANLMASKLGDVRAQVNRAISTVGGLIDALAYLQDLLGGNR-VLGE
Rv3823c|M.tuberculosis_H37Rv KLAGGANLMASKLGDVRAQVNRAISTVGGLIDALAYLQDLLGGNR-VLGE
MAB_0855|M.abscessus_ATCC_1997 KLAAGGHTLADKLGQVRDSVKNSLGTARALVEVLAQLRGS-GRTG-TLAD
MSMEG_4741|M.smegmatis_MC2_155 TLSGGAHKLADVLGQISTQVTNALVTVRPLAGALADMETKYGGEK-TLDQ
MUL_0757|M.ulcerans_Agy99 QQVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIAD
. : : : :
MMAR_4836|M.marinum_M LSATAPAVDQAIRTGPGLRQQADQAQNAIAAIDPLVGALNTSPWCATTPE
TH_3450|M.thermoresistible__bu LSATAPAVDQAIQAGPGLRPWADQAAHAIAILDPLVGALNTAPWCATTPQ
Mflv_4632|M.gilvum_PYR-GCK AFRTADFAGIMPR------------------------AVNSCIRCGLHAA
Mvan_2900|M.vanbaalenii_PYR-1 LNTTAPTVDQALRSGPGLRPLATQASAAIAAVEPLIAGLNASPWCATTPQ
MLBr_01231|M.leprae_Br4923 IDTAGKLVSSMRALGNMFGINFSTTMNDINWVGAVVIALDSSVLCDTNPI
MAV_1761|M.avium_104 VDIAARLVDHVNSLSNAMGWNFTAAKNMFAWIGPVLAALQGNPVCDADSS
Mb3853c|M.bovis_AF2122/97 LEGAEKLIGSMRALGDTIDADASFVANNTEWASPVLGALDSSPMCTADPA
Rv3823c|M.tuberculosis_H37Rv LEGAEKLIGSMRALGDTIDADASFVANNTEWASPVLGALDSSPMCTADPA
MAB_0855|M.abscessus_ATCC_1997 LDSVDKLVTSMHSLGDAIEANAQGASEVYGWIEPVARVLVGNPACDMDPG
MSMEG_4741|M.smegmatis_MC2_155 IDQSAELVANMRSLGRAMGVNLARITDVYDWSAPMVRALNVSPECNLDPA
MUL_0757|M.ulcerans_Agy99 FDDFFRPIR---------------------------SYFYWEKHCFDIPV
. * .
MMAR_4836|M.marinum_M CTQLRDQVQILVTLRHTGFFNQLANLGDLYQPGS--DTAAGTVADVQNTI
TH_3450|M.thermoresistible__bu CAQIRDQVQVLVTLRNSGFFNQVADLGDRYNPATG-ATVAETLADIRNAV
Mflv_4632|M.gilvum_PYR-GCK CGSP---------------------------------TRSEVCADYR---
Mvan_2900|M.vanbaalenii_PYR-1 CAQLRDQTGILVTLRRGGFFDQVADLGDHLGPDT---TLSGTLASLQTAV
MLBr_01231|M.leprae_Br4923 CADARAQFHKLLTASEDGTLDNIAHLWKQLGSTQSSQTIGATVSGLEKTL
MAV_1761|M.avium_104 CSATRATFEQLVGPRGQADLDAIDDLSHQLQAYPDKRALKASTDRLRNAF
Mb3853c|M.bovis_AF2122/97 CASARTELQRLVTARDDGTLAKISELARQLQATRAVQTLAATVSGLRGAL
Rv3823c|M.tuberculosis_H37Rv CASARTELQRLVTARDDGTLAKISELARQLQATRAVQTLAATVSGLRGAL
MAB_0855|M.abscessus_ATCC_1997 CRSSRDEMNKFLETKQDGTRDKIVELGRELKSVDNDKQISSTIARLRTAL
MSMEG_4741|M.smegmatis_MC2_155 CAASRSDLQRIVEAKDNGNLDKFAELGRQLESTEGDETLDEAVSGLQQSI
MUL_0757|M.ulcerans_Agy99 CWSLRSVFDTLDG-------------------------VDLMTEDINNLL
* .
MMAR_4836|M.marinum_M TSLDKTFGAL--GDPADLAGNIRRLQSGISQLASGAQALATGVHTLADSN
TH_3450|M.thermoresistible__bu TAMDKAFGAL--GDPADLAGNIGRLQDGISQLASGAQALATGVHTLVDSN
Mflv_4632|M.gilvum_PYR-GCK --------------TVRYSGQYQLLLSSASDTPCGAHVHFSGLQRMILR-
Mvan_2900|M.vanbaalenii_PYR-1 TTMQQALGVT--GDPADLAGNMRRLQDGVSQLASGGRALASGVHALADSN
MLBr_01231|M.leprae_Br4923 TAVNTSLRSLGLDNPNVMRSKMIGLQNGVNDLASAGRRIADGVAVLVDQT
MAV_1761|M.avium_104 AKLNDVLRAMGMDRPGGLQSNLTTLQNGADQFAGGSRQVADAVAQLVDKV
Mb3853c|M.bovis_AF2122/97 ATVIRAMGSLGMSSPGGVRSKINLVNKGVNDLADGSRQLAEGVQLLVDQV
Rv3823c|M.tuberculosis_H37Rv ATVIRAMGSLGMSSPGGVRSKINLVNKGVNDLADGSRQLAEGVQLLVDQV
MAB_0855|M.abscessus_ATCC_1997 NSIDTNLRRLGLSDSYGIQKRFTEVLTGVNSLADGSAQLAEGVQMLVDQT
MSMEG_4741|M.smegmatis_MC2_155 KEATAAARELGLEDASSVKRQLDQLEQGVNLLADSSHQLAQGVQLLVDQT
MUL_0757|M.ulcerans_Agy99 PLMER------------LDTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQ
: : :
MMAR_4836|M.marinum_M IEMLSGMSQIATQLQNSARTTAGSDNASGFYLPTNAFEN-----------
TH_3450|M.thermoresistible__bu LEMLSGMSQIATQLQNSARASADSDSSSGFYLPPNTFEN-----------
Mflv_4632|M.gilvum_PYR-GCK -----------ARYPNIFRSAPAR----------LSYQG-----------
Mvan_2900|M.vanbaalenii_PYR-1 IQMLGGMSQIAAQLQNSARDTAGSDAAAGFYLPPDSFEN-----------
MLBr_01231|M.leprae_Br4923 RTMGTSLARASAFLMEMGQDASQP-SMAGFNVPPQLLN------------
MAV_1761|M.avium_104 KQLGAGLSESAAFLLSLKHDAAHP-AMAGFNIPAQLLR------------
Mb3853c|M.bovis_AF2122/97 KKMGFGLGEASAFLLAMKDTATTP-AMAGFYIPPELLSYATGESVKAETM
Rv3823c|M.tuberculosis_H37Rv KKMGFGLGEASAFLLAMKDTATTP-AMAGFYIPPELLSYATGESVKAETM
MAB_0855|M.abscessus_ATCC_1997 KQMGGQLGDASTLLVAAKRDAAPG-SMSGFYIPQQVLT------------
MSMEG_4741|M.smegmatis_MC2_155 RNMGQGLDQASQFLLAMKRDASDP-QMSGFYIPPQILT------------
MUL_0757|M.ulcerans_Agy99 QGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVFNN-----------
MMAR_4836|M.marinum_M -------------RQFADVAKHFLSPDGKTARFAIESSYDPYSSDAMNLA
TH_3450|M.thermoresistible__bu -------------RQFADVAKQFLSPDGKTARFAIESSHDPYSVDAMNLA
Mflv_4632|M.gilvum_PYR-GCK -------------RRF----------------------------------
Mvan_2900|M.vanbaalenii_PYR-1 -------------RQFSDVARQFVSADGRTARFAITSSHDPFSAEAMELN
MLBr_01231|M.leprae_Br4923 ------------TEDFKKLVQAFISPDGHSVRYFIQTDLNPFSSAAMDQV
MAV_1761|M.avium_104 ------------LPQFQEAAKVFISPDGHSVRYLVQSKLSPFSTQAMDQV
Mb3853c|M.bovis_AF2122/97 PSEYRDLLGGLNVDQLKKVAAAFISPDGHSIRYLIQTDLNPFSTAAMDQI
Rv3823c|M.tuberculosis_H37Rv PSEYRDLLGGLNVDQLKKVAAAFISPDGHSIRYLIQTDLNPFSTAAMDQI
MAB_0855|M.abscessus_ATCC_1997 ------------QDSFKTAAAAFVSADGHAVRYLVQSNLNPFSPEAMDQV
MSMEG_4741|M.smegmatis_MC2_155 ------------QEEFNKAAALFVSPDGRSVRYLVQTALDPFGTAAMDQV
MUL_0757|M.ulcerans_Agy99 -------------PDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHI
:
MMAR_4836|M.marinum_M HKITEVADAARPNTSLANATVSMAGFPAVNSDIQRLLSADFHQLAFATLV
TH_3450|M.thermoresistible__bu HTITDVADAARPNTSLAHATVSVAGFPAVNSDIARLLWADFAQLAIATIV
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2900|M.vanbaalenii_PYR-1 GRIIDTANAATPNTSLAGTSISIVGFPALNSDLQQLLSTDFARLGAATLL
MLBr_01231|M.leprae_Br4923 NTILNVATGAQPNTTLSDASIYLSGYTVTLRDTRDYYDRDLQLIVIVTMI
MAV_1761|M.avium_104 DAITATARGAQPNTALADAEVSMAGYTVGLKDTRDYYQHDIKFIIAVTLL
Mb3853c|M.bovis_AF2122/97 DAITAAARGAQPNTALADAKVSVVGLPVVLKDTRDYSDHDLRLIIAMTVC
Rv3823c|M.tuberculosis_H37Rv DAITAAARGAQPNTALADAKVSVVGLPVVLKDTRDYSDHDLRLIIAMTVC
MAB_0855|M.abscessus_ATCC_1997 RAIQEAARSAQPNTTLSDASISMAGLSAMYNDIRNYYNHDLRFIIVLTVI
MSMEG_4741|M.smegmatis_MC2_155 KDIVKTAESARPNTSLTDAKISLVGFSSIQNEMRNYYDGDLRFIITVTLI
MUL_0757|M.ulcerans_Agy99 DKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALC
MMAR_4836|M.marinum_M IVGLILVVLLRALVAPLYLLGTVVLNYGAALGLGTLVFQYGLGKEIAWPV
TH_3450|M.thermoresistible__bu IVGLILVLLLRALLAPIYLLGTVVLNYLASLGIGVLVFQYLLGHEIAWPV
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2900|M.vanbaalenii_PYR-1 VVGIVLVLLLRAIVAPLYLLGTVVLNYAAALGIGVLVFQYGFGQAIAWPV
MLBr_01231|M.leprae_Br4923 VVLLILMALLRSIVAPIYLVGSVIVSYLSALGLCVLVFQVLLRQQLHWSV
MAV_1761|M.avium_104 VVLLTLMALLRAIVAPLYLVATVVISYLSAVGVGVLVFQFLLGQQLHWSV
Mb3853c|M.bovis_AF2122/97 IVLLILIVLLRAIVAPLYLIGSVIVSYLAALGIGVIVFQFLLGQEMHWSI
Rv3823c|M.tuberculosis_H37Rv IVLLILIVLLRAIVAPLYLIGSVIVSYLAALGIGVIVFQFLLGQEMHWSI
MAB_0855|M.abscessus_ATCC_1997 VVLLILVALLRAIVAPLYLIGSVIISYASAVGIGVIAFQFIGGQPLSWSV
MSMEG_4741|M.smegmatis_MC2_155 VVFLILAALLRSIIAPIYLVLSVVLSYMSALGIGVVFFQFILGKEIVWTV
MUL_0757|M.ulcerans_Agy99 LIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLV
MMAR_4836|M.marinum_M PLLAFIILVAVGADYNMLLISRLREESAHNIRVGVLRTVANTGSVITSAG
TH_3450|M.thermoresistible__bu PLLAFIILVAVGADYNMLLVSRLREESGTNIRVGVLRTVANTGSVITSAG
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2900|M.vanbaalenii_PYR-1 PLLAFILLVAVGADYNMLLISRLREESGRSVRVGVLRTVASTGSVITSAG
MLBr_01231|M.leprae_Br4923 PGLAFVVLVAVGADYNMLLASRLRDESSHGLRASVIRTVRSTGGVITAAG
MAV_1761|M.avium_104 PPLAFVVLVAVGADYNMLLVSRMRDESPHSMRYGIIRTLSSTGGVITAAG
Mb3853c|M.bovis_AF2122/97 PGLTFVILVAVGADYNMLLISRLREEAVLGVRSGVIRTVASTGGVITAAG
Rv3823c|M.tuberculosis_H37Rv PGLTFVILVAVGADYNMLLISRLREEAVLGVRSGVIRTVASTGGVITAAG
MAB_0855|M.abscessus_ATCC_1997 PGMAFIVLVAVGADYNLLFISRIRDESPDGIRSGVIKTVKSTGGVITSAG
MSMEG_4741|M.smegmatis_MC2_155 PGMAFLVLVAVGADYNLLLISRIRDEAAHGMRTAVIRTIGATGGVITSAG
MUL_0757|M.ulcerans_Agy99 LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG
MMAR_4836|M.marinum_M LIFAASMFGLIAGSIAIMIQAGFIIGCGLLLDTFVVRTLTVPAIATLLRE
TH_3450|M.thermoresistible__bu VIFAASMFGLMFGSIAIMIQAGFIVGCGLLLDTFLVRTLTVPAIATLLRE
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2900|M.vanbaalenii_PYR-1 IIFAVSMFGLMTGSVHIMVQAGFIIGCGLLLDTFVVRTLTVPAIATLLRE
MLBr_01231|M.leprae_Br4923 LIFAASMFGLLLSSIATVVQAGFVLGSGILLDTFIVRTITVPAVAALLRR
MAV_1761|M.avium_104 LIFAASMSGLLFSSIGTVVQGGVVIGVGILLDTFLVRTVTVPAIAALAGR
Mb3853c|M.bovis_AF2122/97 LIMAASMYGLVFASLGSVVQGAFVLGTGLLLDTFLVRTVTVPAIAVLVGQ
Rv3823c|M.tuberculosis_H37Rv LIMAASMYGLVFASLGSVVQGAFVLGTGLLLDTFLVRTVTVPAIAVLVGQ
MAB_0855|M.abscessus_ATCC_1997 VIFAASMFGLLIGNLQSMVEAGFIIGMGLLLDTFLVRTITIPALVVLCGQ
MSMEG_4741|M.smegmatis_MC2_155 LIFAASMFGLTFSSLLAAVQIGFIIGVGLLLDTFLVRTITVPAAAVLIGK
MUL_0757|M.ulcerans_Agy99 LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK
MMAR_4836|M.marinum_M ASWWP-------------QRKPLTHNG-----------------------
TH_3450|M.thermoresistible__bu ASWWP-------------QPNRAR--------------------------
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2900|M.vanbaalenii_PYR-1 KSWWP-------------QR------------------------------
MLBr_01231|M.leprae_Br4923 ASWWP------------ARPWGNNA-------------------------
MAV_1761|M.avium_104 ANWWP------------SRIAVRRNPVSGQP-------------------
Mb3853c|M.bovis_AF2122/97 ANWWLPSSWRPATWWPLGRRRGRAQRTKRKPLLPKEEEEQSPPDDDDLIG
Rv3823c|M.tuberculosis_H37Rv ANWWLPSSWRPATWWPLGRRRGRAQRTKRKPLLPKEEEEQSPPDDDDLIG
MAB_0855|M.abscessus_ATCC_1997 ANWWPSASVESWFRQRFSRSKPDAQEGDCAVSDDPEAASGESSPEEPLIS
MSMEG_4741|M.smegmatis_MC2_155 LSWWP--------------TKPPAP---------------EPAPTEPTVA
MUL_0757|M.ulcerans_Agy99 WFWWPQVVRQRPAPQPWPTPAPTPPPATTSV-------------------
MMAR_4836|M.marinum_M -----------
TH_3450|M.thermoresistible__bu -----------
Mflv_4632|M.gilvum_PYR-GCK -----------
Mvan_2900|M.vanbaalenii_PYR-1 -----------
MLBr_01231|M.leprae_Br4923 -----------
MAV_1761|M.avium_104 -----------
Mb3853c|M.bovis_AF2122/97 LWLHDGLRL--
Rv3823c|M.tuberculosis_H37Rv LWLHDGLRL--
MAB_0855|M.abscessus_ATCC_1997 ASREVELAGRR
MSMEG_4741|M.smegmatis_MC2_155 PAAQA------
MUL_0757|M.ulcerans_Agy99 -----------