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VSIGDQLEFIAPMPRLLDDGSAWVEELRRLEEFGFDTVSVSHHVTSGWQLAPVAAMAFAAASTSRLKVLT LVAQNPLQHPALLAKDIATIDRLSGGRAELGLGAGWLAADYAALGVPFESHRTRVDQCAEALTIIRDFFT EDTVDFVGHHYHVTGLEALPRCCRQPSPPILLGAAGPRMLDLGGRSADIVGVLPRMVNGRIDHETVADVA APSLHAKIARVRDSAARAGRQMPRIQFSVLHLDVTDVESPPRPVTQWEEALATERNWPLHGTPACLVGTA AECAEQVAEFSHRFGIGYWHLGQDSRAAAAVIAHLH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0205 | - | - | 100% (316) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_0757 | - | 9e-35 | 33.81% (281) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4930 | - | 1e-23 | 29.09% (275) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2917 | - | 2e-29 | 31.83% (289) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0268 | - | 4e-24 | 28.62% (297) | luciferase family protein |
| M. tuberculosis H37Rv | Rv2893 | - | 2e-29 | 31.83% (289) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 3e-09 | 29.72% (212) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4277 | - | 7e-23 | 28.94% (273) | luciferase-like monooxygenase superfamily protein |
| M. marinum M | MMAR_2775 | - | 7e-25 | 28.90% (301) | oxidoreductase |
| M. avium 104 | MAV_5129 | - | 6e-22 | 40.58% (138) | hypothetical protein MAV_5129 |
| M. smegmatis MC2 155 | MSMEG_2516 | - | 1e-36 | 34.98% (283) | putative oxidoreductase |
| M. thermoresistible (build 8) | TH_2824 | - | 4e-23 | 28.42% (278) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2972 | - | 2e-24 | 28.57% (301) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0268|M.gilvum_PYR-GCK -------------------MSSVDFRVFVEPQQGASYADQLAVARTAEQA
TH_2824|M.thermoresistible__bu ----------------------MDFRVFVEPQQGGTYADQLAVARAAEDL
MAB_4277|M.abscessus_ATCC_1997 ----------------------MDFRVFVEPQQGATYSDQLRVAQAAEEL
Mb2917|M.bovis_AF2122/97 ------------MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAA
Rv2893|M.tuberculosis_H37Rv ------------MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAA
MSMEG_2516|M.smegmatis_MC2_155 ------------------------MRFGLHTALPR-GTDFAEFARGVEDS
MMAR_2775|M.marinum_M MTLRLPRTRWLARLPAGSVTPVPEFRFSFNVFRIDPVHTFIETCRRAEQW
MUL_2972|M.ulcerans_Agy99 ---------------------MPEFRFSFNVFRIDPVHTFIETCRRAEQW
Mvan_0205|M.vanbaalenii_PYR-1 -----------------MSIGDQLEFIAPMPRLLDDGSAWVEELRRLEEF
MAV_5129|M.avium_104 ----------------MRFTITHPMHSHPYNRELVSGDAIAKVAAATEAA
MLBr_00348|M.leprae_Br4923 ---------------MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGA
*
Mflv_0268|M.gilvum_PYR-GCK GYSAFFRSDHYLAMA--G-DGLPGPTDSWVTLAGLARETSSIRLGTMVTS
TH_2824|M.thermoresistible__bu GYSAFFRSDHYLAMS--G-DGLPGPTDSWVTLAGIARETTSIRLGTLVTS
MAB_4277|M.abscessus_ATCC_1997 GFSAFFRSDHYLAMG--GADGLPGPTDAWVTLGAIARETTAIRLGTLVTS
Mb2917|M.bovis_AF2122/97 GFDVLAFP-----------DHLVPSVSPFAGATAAAMATQRLHTGTLVLN
Rv2893|M.tuberculosis_H37Rv GFDVLAFP-----------DHLVPSVSPFAGATAAAMATQRLHTGTLVLN
MSMEG_2516|M.smegmatis_MC2_155 GFDVLTVP-----------DHIAPILSPFAGCAAAGAVTSRLHTGTLVLN
MMAR_2775|M.marinum_M GYDAVFAA-----------DHLG-IAAPFMTLVAAAAATDRMRVGTLVLN
MUL_2972|M.ulcerans_Agy99 GYDAVFAA-----------DHLG-IAAPFMTLVAAAAATDRMRVGILLLN
Mvan_0205|M.vanbaalenii_PYR-1 GFDTVSVS---------HHVTSGWQLAPVAAMAFAAASTSRLKVLTLVAQ
MAV_5129|M.avium_104 GIHGFGFTDHPAPSQRWLEAGGHDALDPFVALGFAAATTSTLRLIPNIVV
MLBr_00348|M.leprae_Br4923 GFDAVFTG-------------EAWGSDAYTPLAWWGSSTQRVRLGTSVVQ
* . . . * :: :
Mflv_0268|M.gilvum_PYR-GCK ATFRHPGPLAISVAQVDEMSGGRVELGLGAGWFEAEHKAYAIPFPPLGER
TH_2824|M.thermoresistible__bu ATFRYPGPLAISVAQVDEMSGGRVEFGLGSGWFEPEHQAYAIPFPPLGER
MAB_4277|M.abscessus_ATCC_1997 ATFRHPGPLAVTVAQVDEMSSGRVDFGLGAGWFSEEHEAYAIPFPSLGER
Mb2917|M.bovis_AF2122/97 NDFRHPVDTAREAAGVATLAEGRFELGLGAGHRRSEYDAAGITFDSGATR
Rv2893|M.tuberculosis_H37Rv NDFRHPVDTAREAAGVATLAEGRFELGLGAGHRRSEYDAAGITFDSGATR
MSMEG_2516|M.smegmatis_MC2_155 NDLRHPVDVARESGTLAAMSGGRFELGLGAGHMKSEYDAVGVKFDRGGVR
MMAR_2775|M.marinum_M APWWNPALLARDIATTDVLTGGRLEVGLGAGHMKWEYDQADIPFPSFTTR
MUL_2972|M.ulcerans_Agy99 APWWNPALLARDIATTDVLTGGRLEVGLGAGHMKWEYDQADIPFPSFTTR
Mvan_0205|M.vanbaalenii_PYR-1 NPLQHPALLAKDIATIDRLSGGRAELGLGAGWLAADYAALGVPFESHRTR
MAV_5129|M.avium_104 LPYRNPFVVAKSGATLDLLSGGRFTLAVGVGYLKREFAALGVSYD---ER
MLBr_00348|M.leprae_Br4923 LSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFP---KP
* * :: ** ..:* . :
Mflv_0268|M.gilvum_PYR-GCK FDRLTEQLEILTGLWTTPTGETFDYSGTHY----SIADSPALPKPAQ---
TH_2824|M.thermoresistible__bu FDRLTEQLEIITGLWTTPSGEKYDFTGKHY----TVVDSPGLPKPVQ---
MAB_4277|M.abscessus_ATCC_1997 FDRLEEQLEILTGLWTTPTGDTYSYAGKHY----TVTDSPALPKPVQ---
Mb2917|M.bovis_AF2122/97 VARLIESAHLIRALLDAEP---VDFDGQHY----RVHAEAGSLVAPP---
Rv2893|M.tuberculosis_H37Rv VARLIESAHLIRALLDAEP---VDFDGQHY----RVHAEAGSLVAPP---
MSMEG_2516|M.smegmatis_MC2_155 VDRLVEAVSVIAPLLAGEA---VDVDGSHY----CVRGAAGELVAPP---
MMAR_2775|M.marinum_M TARLRQTIEELASRFAEEG---FAQQAELR----EAHNIAVLRPTQRRGF
MUL_2972|M.ulcerans_Agy99 TARLRQTIEELASRFAEDG---FAQQAELR----EAHNIAVLRPTQRRGF
Mvan_0205|M.vanbaalenii_PYR-1 VDQCAEALTIIRDFFTEDT---VDFVGHHY----HVTGLEALPRCCR---
MAV_5129|M.avium_104 AELFEEALQVIRAVWTGDD---ISFEGRHF----SARGITAHPRPVS---
MLBr_00348|M.leprae_Br4923 LSRTREYIDIVRQVWAREAP--VVSDGQHYPLPLTGAGATGLGKALKPIT
: : .
Mflv_0268|M.gilvum_PYR-GCK ---SPRPPIVIGGRGAKRTPALTARFADEFNIP-----------FVPLDE
TH_2824|M.thermoresistible__bu ---DPYPPIIIGGQGPKRTPALAARFANEFNIP-----------FVRLDA
MAB_4277|M.abscessus_ATCC_1997 ---EPHPPIVIGGLGVKRTPALAARFATEFNLP-----------FQPVDV
Mb2917|M.bovis_AF2122/97 ---KVRVPLLVGGNG-TEVLRLGGRIADIVGLAGISHNRDATQVRFTHFD
Rv2893|M.tuberculosis_H37Rv ---KVRVPLLVGGNG-TEVLRLGGRIADIVGLAGISHNRDATQVRFTHFD
MSMEG_2516|M.smegmatis_MC2_155 ---GVPVPLLIGGNG-TRVLQLAGRVADIAGLAGFSHNHDATEIRLTHFG
MMAR_2775|M.marinum_M G--GYGPPLLVGGTG-DQVLRLAAQYADTVSIACLYQVKGRPPGTMRLAT
MUL_2972|M.ulcerans_Agy99 G--GYGPPLLVGGTG-DQVLRLAAQYADTVSIACLYQVKGRPPGTMRLAI
Mvan_0205|M.vanbaalenii_PYR-1 ---QPSPPILLGAAG-PRMLDLGGRSADIVGVLPRMVNGRIDHETVADVA
MAV_5129|M.avium_104 ---SPHPPIWIGGNTAAARQRVADYGDGWCPFP-----------APPQLA
MLBr_00348|M.leprae_Br4923 HPLRADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGF
*: :*. .
Mflv_0268|M.gilvum_PYR-GCK LTTQYAR---------VAAAVEDAGRAKDSLTYSAAFVVCVG--RDD---
TH_2824|M.thermoresistible__bu LKAQFER---------VAAAVAEAGREPDSMIYSAAFVLCAG--RDD---
MAB_4277|M.abscessus_ATCC_1997 ITDQYAR---------VAHAVEAAGRPADSMTYSAAFALCIG--DTD---
Mb2917|M.bovis_AF2122/97 ADGLADR---------IAVVRHAAGDRFEAIELNALIQAVVC--TNDRNA
Rv2893|M.tuberculosis_H37Rv ADGLADR---------IAVVRHAAGDRFEAIELNALIQAVVC--TNDRNA
MSMEG_2516|M.smegmatis_MC2_155 PAGLLDR---------IGVVRDAAGARFEQIELNALIQFVAH--TEDPAA
MMAR_2775|M.marinum_M VAEIEQR---------VAYVRRCAG-AARHPELHTLIQEVVL--TDDRRK
MUL_2972|M.ulcerans_Agy99 VAEIEQR---------VAYVRRCAG-AARHPELHTLIQEVVL--TDDRRE
Mvan_0205|M.vanbaalenii_PYR-1 APSLHAK---------IARVRDSAARAGRQMPRIQFSVLHLD--VTDVES
MAV_5129|M.avium_104 RTAGTAV---------IDSVAKLADGIADLRRRCDAAQRDWS--TIDITF
MLBr_00348|M.leprae_Br4923 ARTGARRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTN
:
Mflv_0268|M.gilvum_PYR-GCK --AEIARRAAAIGREVDEMRS--NSPTVGTPAEVVDKLGPFLEAGVERVY
TH_2824|M.thermoresistible__bu --AEIARRAAAINREVDELRS--NSPVVGTPAEIVDRLGPFIEAGVQRVY
MAB_4277|M.abscessus_ATCC_1997 --ADIARRAANIGREVEEITE--NSPLAGTPDAVAEKLSIYVDAGVQRVY
Mb2917|M.bovis_AF2122/97 AAAELAATLGG-ITPEQVLES--PFLLLGTHEQMAEALAARQRRFGVSYW
Rv2893|M.tuberculosis_H37Rv AAAELAATLGG-ITPEQVLES--PFLLLGTHEQMAEALAARQRRFGVSYW
MSMEG_2516|M.smegmatis_MC2_155 AAAELAGTLG--TEPSVLLES--PFVLIGTYEQMAEALAERQRLYGVSYW
MMAR_2775|M.marinum_M VAGMLAAKYGNLLTANEILQS--PTLLIGTVEQIARQLRANRERYGFTHY
MUL_2972|M.ulcerans_Agy99 VAGMLAAKYGNLLTANEILQS--PTLLIGTVEQIARQLRANRERYGFTHY
Mvan_0205|M.vanbaalenii_PYR-1 PPRPVTQWEEALATERNWPLHGTPACLVGTAAECAEQVAEFSHRFGIGYW
MAV_5129|M.avium_104 TNFEGGSPADDEFNADAYLDG------LDKLAKLGVTWVS-VHLPGDSMA
MLBr_00348|M.leprae_Br4923 FHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDY
Mflv_0268|M.gilvum_PYR-GCK LQVLDMSDLEH---VEFFAEQVIPQIH------
TH_2824|M.thermoresistible__bu LQLLDMSDLDH---LELIATQVVPQLR------
MAB_4277|M.abscessus_ATCC_1997 VQLLDIRDLDH---LEFFASTVIPQFS------
Mb2917|M.bovis_AF2122/97 TVFDEWAGRAS---AMRDIAEVIALLRYG----
Rv2893|M.tuberculosis_H37Rv TVFDEWAGRAS---AMRDIAEVIALLRYG----
MSMEG_2516|M.smegmatis_MC2_155 TVIDAWAGRES---AMPHLAEVIKLLR------
MMAR_2775|M.marinum_M TIPQPHVAAFA---PVITVLGDLN---------
MUL_2972|M.ulcerans_Agy99 TIPQPHVAAFA---PVITVLGDLN---------
Mvan_0205|M.vanbaalenii_PYR-1 HLGQDSRAAAA---VIAHLH-------------
MAV_5129|M.avium_104 HALETLDRFRT---LVVDAA-------------
MLBr_00348|M.leprae_Br4923 VCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF