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MPTTRSFDALLRSALDLIADGGIDGLTLSQVAEHAHVSRATAYREFGDKDGLVGAVAQHEIGLMLVAVHA DIDTTADATALVASIVVSALRYLRSHRAFTYVRTHEPHWLLHAALAVGDSRTDLVQTVAAAVTPAIAVDT RRLRLSAVQAAEVMVRTVLSHTLIEYSTLTDAQVGEAVAHALITD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0202 | - | - | 100% (186) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4249 | - | 2e-08 | 30.07% (143) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3780 | - | 2e-07 | 27.45% (153) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 2e-09 | 30.17% (179) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5008 | - | 1e-07 | 33.65% (104) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2250c | - | 5e-09 | 30.17% (179) | transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 6e-10 | 27.37% (179) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4449c | - | 3e-08 | 27.78% (126) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3158 | - | 3e-09 | 27.27% (176) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4919 | - | 1e-08 | 24.00% (150) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5307 | - | 2e-08 | 35.90% (78) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 7e-08 | 30.19% (106) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_1163 | - | 2e-08 | 27.50% (120) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4919|M.avium_104 -MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAQAQISKPML
MUL_1163|M.ulcerans_Agy99 -MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAAQISKPML
MLBr_02568|M.leprae_Br4923 -MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPML
MAB_4449c|M.abscessus_ATCC_199 -MAGGTKRLPRAVREQQMLDAAVQEFALNGFRDTSMDAIAAAAKISKPML
Mb2274c|M.bovis_AF2122/97 -MLSMSN--DRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTV
Rv2250c|M.tuberculosis_H37Rv -MLSMSN--DRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTV
Mvan_0202|M.vanbaalenii_PYR-1 -------MMPTTRSFDALLRSALDLIADGGIDGLTLSQVAEHAHVSRATA
MMAR_3158|M.marinum_M MPTDSARMSFRRHIREQVLRATRELTIEKGWEQVRVSEVAELVGVSRPTL
TH_2255|M.thermoresistible__bu ------MPERPDPARQAILDAAVVEFEQHGFRKVALEDVARRAGVSRTTI
MSMEG_5307|M.smegmatis_MC2_155 ---MAKATSSVLPPAERILAAAADLLRAGGIDAVSTRAVATEAGVQPPTI
Mflv_5008|M.gilvum_PYR-GCK MTAPVRGRPRDPDADRAILQAALDLFIERGVEGSSIEQIAKRAGVGKPTV
:* :: * :* . : .
MAV_4919|M.avium_104 YLYYGSKEDLFGACLNRELGRFIDAVRADIDFQQ-SPNDMLRNTIASFMR
MUL_1163|M.ulcerans_Agy99 YLYYGSKEDLFGACLNREMSRFIDAVRADIDLSQ-SPKDLLRNAIVSFLR
MLBr_02568|M.leprae_Br4923 YLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQ-SPKDLLRNTIVSFLR
MAB_4449c|M.abscessus_ATCC_199 YLYYGSKEDLFVACLRRELGRFVEAVRGDIDLTQ-SPRDVLSTTVVSFLN
Mb2274c|M.bovis_AF2122/97 YRRWPDTRSIMASMLT----SHIAAVLREVPLDG-DDREALVKQIVAVAD
Rv2250c|M.tuberculosis_H37Rv YRRWPDTRSIMASMLT----SHIADVLREVPLDG-DDREALVKQIVAVAD
Mvan_0202|M.vanbaalenii_PYR-1 YREFGDKDGLVGAVAQHEIGLMLVAVHADIDTTA-DATALVASIVVSALR
MMAR_3158|M.marinum_M YKEFGDKQGLGDALVVAEGQRFLEGIHAILAEHTGDVQGGITAAVRFTLR
TH_2255|M.thermoresistible__bu YRRFTNRDELVAAVVDRENAALFADIAAELKHSG-PQGDYYVEAFTLAIL
MSMEG_5307|M.smegmatis_MC2_155 YRQFGDKDGLLDAVTRHVLESYIDRKRLLTDPDA-DPALILRELWDLHVE
Mflv_5008|M.gilvum_PYR-GCK YRRWGTKEELIAAAMETLVAEEVGWTSPEAIETR-SPHVLVEAAIDSAAA
* : : : .
MAV_4919|M.avium_104 YIDANRASWIVMYTQATSSQAFAHMVR-------------------EGRE
MUL_1163|M.ulcerans_Agy99 YIDQNQASWIVMYTQAVSSQAFAQTVR-------------------EGRE
MLBr_02568|M.leprae_Br4923 YIDANRASWIVMYIQAMSLPAFAQTVR-------------------EARD
MAB_4449c|M.abscessus_ATCC_199 YVDTHRASWIVIYGQATSTQLFAKQVR-------------------EGRD
Mb2274c|M.bovis_AF2122/97 RLRGDDLIMSVMHSELARVYITERLGT-------------------SQQV
Rv2250c|M.tuberculosis_H37Rv RLRGDDLIMSVMHSELARVYITERLGT-------------------SQQV
Mvan_0202|M.vanbaalenii_PYR-1 YLRSHRAFTYVRTHEPHWLLHAALAVG-------------------DSRT
MMAR_3158|M.marinum_M EAEASPLLKSVLTSSHSGDDRAGAPTTGVLPLL-------------PTSA
TH_2255|M.thermoresistible__bu KFRRHRVLHRMITDEPGFILHLAQQHWG---------------------A
MSMEG_5307|M.smegmatis_MC2_155 FGMQQPHCYLLTYGQGRRTSAADETVSILGEVIGRLGAAGRLTMSVRRAT
Mflv_5008|M.gilvum_PYR-GCK ATAAPYYRALVARVYGSAVSHPELMTVY-----------------WDRYI
:
MAV_4919|M.avium_104 QIIELVAGLMRAGSRTPRTDRE-HEMMAVALVGAGEAVANRLSTGDIDVD
MUL_1163|M.ulcerans_Agy99 QIVELVAGMLRAGTRSPRSDAE-IDMMAAALVGAGEAVANRLSAGDTDVD
MLBr_02568|M.leprae_Br4923 QITELVAGLMRVGTRSSRPDHE-YEIMAGALVGAGEAMATRLTTGDIAVD
MAB_4449c|M.abscessus_ATCC_199 RIIELVARLIKAASPEIDPETD-YDAMAVALVGGGEAVASRVATGDIKVE
Mb2274c|M.bovis_AF2122/97 LIEGLAARLTVAQRSGSVRSGD-ARRLATMVLLIAQSTIQSADIVDSILD
Rv2250c|M.tuberculosis_H37Rv LIEGLAARLTVAQRSGSVRSGD-ARRLATMVLLIAQSTIQSADIVDSILD
Mvan_0202|M.vanbaalenii_PYR-1 DLVQTVAAAVTPAIAVDTRRLR-LSAVQAAEVMVRTVLSHTLIEYSTLTD
MMAR_3158|M.marinum_M SLLQLSSAALVAWFHDHFADLDSEDVEEVADVLVRLTVSHVVLPSADIAT
TH_2255|M.thermoresistible__bu AVERMAEALRVIFPAGFAERIGEAAVIEFADTILRYAAMALLLPSVQPLD
MSMEG_5307|M.smegmatis_MC2_155 DYFRASGTGFVMSQLSLASEERDAELSGIIFEATLAAVSTDGRRGRGRKA
Mflv_5008|M.gilvum_PYR-GCK LPRRVQATRLLERARELGTVAADTDLDVAIDMMVGAITYRVLRPNPPDVD
MAV_4919|M.avium_104 EAAALMIDLFWYGLKGSPEEREAAAAQPEADRSGAGG----
MUL_1163|M.ulcerans_Agy99 EAAEMMIDLLWRGLKGAPSDREIGSNFAAG-----------
MLBr_02568|M.leprae_Br4923 EAAELMINLFWHGLKGAPADRDFGPSIVAG-----------
MAB_4449c|M.abscessus_ATCC_199 SAKDTLLNLGWRGLRGRPRDEPVAKRA--------------
Mb2274c|M.bovis_AF2122/97 SAA--LATELTHALNGYLC----------------------
Rv2250c|M.tuberculosis_H37Rv SAA--LATELTHALNGYLC----------------------
Mvan_0202|M.vanbaalenii_PYR-1 AQVG---EAVAHALITD------------------------
MMAR_3158|M.marinum_M TGARISRVALRYLGVGYR-----------------------
TH_2255|M.thermoresistible__bu TADDIRAFATRHFLPSLPAALHTGSA---------------
MSMEG_5307|M.smegmatis_MC2_155 NDVRARAVALREALPESRTPALSAAEQGLLAEWLDRLADQA
Mflv_5008|M.gilvum_PYR-GCK EMRRYLREVYRQAGLLPPG----------------------