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PTDSARMSFRRHIREQVLRATRELTIEKGWEQVRVSEVAELVGVSRPTLYKEFGDKQGLGDALVVAEGQR FLEGIHAILAEHTGDVQGGITAAVRFTLREAEASPLLKSVLTSSHSGDDRAGAPTTGVLPLLPTSASLLQ LSSAALVAWFHDHFADLDSEDVEEVADVLVRLTVSHVVLPSADIATTGARISRVALRYLGVGYR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3158 | - | - | 100% (205) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1294 | - | 3e-19 | 29.51% (183) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3519 | - | 2e-08 | 20.77% (183) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 4e-19 | 30.65% (186) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4718 | - | 8e-19 | 29.51% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3249c | - | 4e-19 | 30.65% (186) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2046 | - | 2e-91 | 82.67% (202) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4212 | - | 1e-19 | 31.18% (186) | putative transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1842 | - | 2e-17 | 29.32% (191) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0467 | - | 1e-19 | 30.60% (183) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2593 | - | 4e-19 | 29.51% (183) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1745 | - | 9e-19 | 29.51% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4718|M.gilvum_PYR-GCK -MTAQPIATSARVATRHADQRRADTRARGASLGPVRATVIVAPVGG-GND
Mvan_1745|M.vanbaalenii_PYR-1 -MRATHRAEPC----RHARSRNTASQGTAVTASAGPGTITVARVGL-SND
TH_0467|M.thermoresistible__bu ---------------------------------------VVSRR-----D
MSMEG_1842|M.smegmatis_MC2_155 MIHAVTHAVAG---------AQFGAPARVVRGPLTAESDIVARVSRPRAK
Mb3277c|M.bovis_AF2122/97 -----------------------------------MSTPSAT----VAPV
Rv3249c|M.tuberculosis_H37Rv -----------------------------------MSTPSAT----VAPV
MUL_2593|M.ulcerans_Agy99 ---------------MPRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPV
MAV_4212|M.avium_104 -------------------------------------------------M
MMAR_3158|M.marinum_M -------------------------------------------------M
MAB_2046|M.abscessus_ATCC_1997 -------------------------------------------------M
Mflv_4718|M.gilvum_PYR-GCK KRISYAEASRVLLRDSILDGMREMLLARDWSQITLSDVAKAAGISRQTIY
Mvan_1745|M.vanbaalenii_PYR-1 KRVSYAEASRVLLRDSILDGMREMLLTRDWSAITLSDVAKAAGISRQTIY
TH_0467|M.thermoresistible__bu KRVPYAEASRVLLRDSILDGMRELLQTRDWSQITLADVAKAAGISRQTIY
MSMEG_1842|M.smegmatis_MC2_155 QRMPYAEASRVLLRDSILDGMRDLLLTRDWSAITLSHVAQAAGVSRQTIY
Mb3277c|M.bovis_AF2122/97 KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
Rv3249c|M.tuberculosis_H37Rv KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
MUL_2593|M.ulcerans_Agy99 KRVPYAEASRVLLRDSVLDAMRDLLFTRDWSAITLSDVARSAGISRQTIY
MAV_4212|M.avium_104 KRMPYAEASRALLRDSVLDAMRDLLVTRDWSAITLSDVARAAGISRQTIY
MMAR_3158|M.marinum_M PTDSARMSFRRHIREQVLRATRELTIEKGWEQVRVSEVAELVGVSRPTLY
MAB_2046|M.abscessus_ATCC_1997 PTEPVRVSFRRHVREKVLRATRELAIEKGWDQVRMSEVAESVGVSRPTLY
. : * :*:.:* . *:: :.*. : ::.**. .*:** *:*
Mflv_4718|M.gilvum_PYR-GCK NEFGSRQGLAQGYAMRLADRLVDQIHAAIDNNVGDMYAAFLQGFRDFFVE
Mvan_1745|M.vanbaalenii_PYR-1 NEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRDFFVE
TH_0467|M.thermoresistible__bu NEFGSRQGLAQGYALRLADRLVDEVDEAIANNVGDIHAAFLAGFRKFFAE
MSMEG_1842|M.smegmatis_MC2_155 NEFGSRQGLAEGYAMRLADRLVDAVDDAINNNVGDVYAAFLEGFRAFFAE
Mb3277c|M.bovis_AF2122/97 NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
Rv3249c|M.tuberculosis_H37Rv NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
MUL_2593|M.ulcerans_Agy99 NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MAV_4212|M.avium_104 NEFGSRQGLAQGYALRLADRLVDTIHEALDAHVGNIYESFLDAFRRFFAD
MMAR_3158|M.marinum_M KEFGDKQGLGDALVVAEGQRFLEGIHAILAEHTGDVQGGITAAVRFTLRE
MAB_2046|M.abscessus_ATCC_1997 KEFGDKQGLGDALVVSEGQRFMEGILAVLAEHVGDVRGGITAAVQFTLCE
:***.:***.:. .: .:*::: : : :.*:. .: ..: : :
Mflv_4718|M.gilvum_PYR-GCK SAADPLVISLLT---------GSSKPDLLQLITTDSAPIINHCSSRLTES
Mvan_1745|M.vanbaalenii_PYR-1 SAADPLVISLLT---------GTSKPDLLQLITTDSAPIINHCSSRLTES
TH_0467|M.thermoresistible__bu SAADPLVISLLT---------GSAKPDLLQLITTDSAPIITRASQRLTES
MSMEG_1842|M.smegmatis_MC2_155 SAADPLVISLLT---------GAAKPDLLQIITIGSGPIITRCSERLTAT
Mb3277c|M.bovis_AF2122/97 SAADPLVISLLT---------GVAKPDLLQLITTDSAPIITRASARLAPA
Rv3249c|M.tuberculosis_H37Rv SAADPLVISLLT---------GVAKPDLLQLITTDSAPIITRASARLAPA
MUL_2593|M.ulcerans_Agy99 SAADPLVISLLT---------GVAKPDLLQLITTDSAPIITRASARLATA
MAV_4212|M.avium_104 AAADPLVTSLRT---------GVAKPDLLQLITTDSAVIITRASARLASA
MMAR_3158|M.marinum_M AEASPLLKSVLTSSHSGDDRAGAPTTGVLPLLPT-SASLLQLSSAALVAW
MAB_2046|M.abscessus_ATCC_1997 AEDSPLLKAVLTSNPSGNDRGGSSSTGVLPLLPT-SASLLQLCSAALITW
: .**: :: * * ....:* ::. *. :: .* *
Mflv_4718|M.gilvum_PYR-GCK LMGSWVRCSEEDAGVLSRAIVRLAMSYISMPPEADHDVARDLARLMTPFA
Mvan_1745|M.vanbaalenii_PYR-1 FMSSWVRVSQEDAGVLARAIVRLAMSYISMPPEADHDVARDLARLMTPFA
TH_0467|M.thermoresistible__bu FQSSWVRASEEDAGVLARAIVRLAMSYVSMPPEADHDVAHDLARLMTPFA
MSMEG_1842|M.smegmatis_MC2_155 FQSSWIKASDDDAGVLARAIVRLAMSYVSMPPEADHDVAGDLARLMSPFA
Mb3277c|M.bovis_AF2122/97 FTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFA
Rv3249c|M.tuberculosis_H37Rv FTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFA
MUL_2593|M.ulcerans_Agy99 FTQTWVATSDDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFA
MAV_4212|M.avium_104 LTHTWVSTTDEDAGVLARAIVRLALSYVSMPPEADHDVAADLARLMTPFA
MMAR_3158|M.marinum_M FHDHFADLDSEDVEEVADVLVRLTVSHVVLP---SADIATTGARISRVAL
MAB_2046|M.abscessus_ATCC_1997 FNDHFDDLDPEDVEEVADVLVRLTVSHVVLP---AADIATTGERISRVAL
: : :*. :: .:*** :*:: :* ::* *:
Mflv_4718|M.gilvum_PYR-GCK ERYGVVADPVEGGNSQVTRRP
Mvan_1745|M.vanbaalenii_PYR-1 ERYGVIDP-------------
TH_0467|M.thermoresistible__bu ERYGVIEEV------------
MSMEG_1842|M.smegmatis_MC2_155 ERYGVIDTP------------
Mb3277c|M.bovis_AF2122/97 ERHGVINVP------------
Rv3249c|M.tuberculosis_H37Rv ERHGVINVP------------
MUL_2593|M.ulcerans_Agy99 ERHGVINVP------------
MAV_4212|M.avium_104 ERHGVVNVG------------
MMAR_3158|M.marinum_M RYLGVGYR-------------
MAB_2046|M.abscessus_ATCC_1997 RYLGVVHSL------------
. **