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VPSTNDGAIRIDSVSHHYGSGGAEVTALGPVDLTVDPGSFLVLVGASGCGKSTLLRLLAGFEEPSQGSVQ VAGARPTPGVTAGVVFQQPRLFPWRTVGGNVDMALRYAKVPRDKRIERREELLGRVGLEGTADRRIWEIS GGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSAESGRTTVFVTHSADEAAFLGSRIV VLTRRPGQVALDIPVDLPRTGVDPDELRRSPEYGQLRAEVGRAVKAAAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0123 | - | - | 100% (259) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3141 | - | 7e-40 | 38.06% (247) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_5731 | - | 4e-38 | 41.71% (211) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1270 | sugC | 2e-33 | 37.98% (208) | sugar-transport ATP-binding protein ABC transporter SugC |
| M. gilvum PYR-GCK | Mflv_0722 | - | 1e-125 | 87.60% (258) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1238 | sugC | 2e-33 | 37.98% (208) | sugar-transport ATP-binding protein ABC transporter SugC |
| M. leprae Br4923 | MLBr_01089 | - | 6e-33 | 37.02% (208) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2178 | - | 1e-124 | 84.17% (259) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0034 | proV_1 | 2e-35 | 38.96% (231) | osmoprotectant (glycine |
| M. avium 104 | MAV_0140 | - | 3e-38 | 41.13% (231) | ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit |
| M. smegmatis MC2 155 | MSMEG_0116 | - | 1e-119 | 83.07% (254) | taurine import ATP-binding protein TauB |
| M. thermoresistible (build 8) | TH_3667 | - | 3e-36 | 44.28% (201) | PUTATIVE ferric cations import ATP-binding protein FbpC |
| M. ulcerans Agy99 | MUL_0033 | proV_1 | 4e-34 | 38.10% (231) | osmoprotectant (glycine |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0123|M.vanbaalenii_PYR-1 ----------------MPSTND----------GAIRIDSVSHHYGSGGAE
Mflv_0722|M.gilvum_PYR-GCK ----------------MSSQSDTEPVAPQRRSGAIQIRSVSHRYGQGRDE
MAB_2178|M.abscessus_ATCC_1997 ----------------MPLVDEAETAVQERDTGSIRISGVTHSYGSGAGK
MSMEG_0116|M.smegmatis_MC2_155 ----------------MPSASEAGPG----AEGELRIRNVAHRYGRGPNE
MMAR_0034|M.marinum_M --------------MPEAASADQPTTSDAPQSSGLRILLDGVTKRYGVRS
MUL_0033|M.ulcerans_Agy99 --------------MPEAASADQPTTSDAPQSSGLRILLDGVTKRYGVRS
MAV_0140|M.avium_104 --------------------------------------------------
TH_3667|M.thermoresistible__bu VIKTMKTKPADTSGAGPAVSNPAVSNPDVSAPQLRGADVEVQGLHKSFGA
Mb1270|M.bovis_AF2122/97 ----------------------------------MAEIVLDHVNKSYPDG
Rv1238|M.tuberculosis_H37Rv ----------------------------------MAEIVLDHVNKSYPDG
MLBr_01089|M.leprae_Br4923 ----------------------------------MAEIVLEHVNKNYPNG
Mvan_0123|M.vanbaalenii_PYR-1 VTALGPVDLTVDPGSFLVLVGASGCGKSTLLRLLAGFEEPSQGSVQVAGA
Mflv_0722|M.gilvum_PYR-GCK VTALGPVDLTVEPGSFLVLVGASGCGKSTLLRLLAGFESPTDGSVDVEGV
MAB_2178|M.abscessus_ATCC_1997 TTALGPVDLTVEPGTFLVLVGASGCGKSTLLRLLAGFESPSEGAVRVAGG
MSMEG_0116|M.smegmatis_MC2_155 VTALGPVDLDVEPGAFVVLVGASGCGKSTLLRLIAGFETPTEGEVVVAGS
MMAR_0034|M.marinum_M TPAVDNVTLEIGAGEIVMLVGPSGCGKTTTMKMINRLIEPTSGRIFIGDD
MUL_0033|M.ulcerans_Agy99 TPAVDNVTLEIGAGEIVMLVGPSGCGKTTTMKVINRLIEPTSGRIFIGDD
MAV_0140|M.avium_104 --MLRDVDVEIEPGAVVALLGASGSGKSTLLRLVAGLDRPSGGRIEIDGK
TH_3667|M.thermoresistible__bu KAVLRGVDLTVSAGTLTAVLGPSGCGKTTLLRILAGFDDPDAGTVRIGGH
Mb1270|M.bovis_AF2122/97 HTAVRDLNLTIADGEFLILVGPSGCGKTTTLNMIAGLEDISSGELRIAGE
Rv1238|M.tuberculosis_H37Rv HTAVRDLNLTIADGEFLILVGPSGCGKTTTLNMIAGLEDISSGELRIAGE
MLBr_01089|M.leprae_Br4923 ATAVHDLSITVADGEFLILIGPSGCGKTTTLNMIAGLEDISSGELRIDGD
: : : : * . ::*.**.**:* :.:: : * : : .
Mvan_0123|M.vanbaalenii_PYR-1 RPTPG--------VTAGVVFQQPRLFPWRTVGGNVDMALRYAKVPRDKRI
Mflv_0722|M.gilvum_PYR-GCK PPTPG--------VTAGVVFQQPRLFPWRTVGGNVELALKYAKVPRDKRS
MAB_2178|M.abscessus_ATCC_1997 VPTPG--------ITSGVVFQQPRLFPWRTVGGNIELALKYAKVPRERWA
MSMEG_0116|M.smegmatis_MC2_155 RPTPG--------VTSGVVFQQPRLFPWRTVGGNIDLALKYAKVPRERRA
MMAR_0034|M.marinum_M DVTRRNPD--ELRRHIGYVVQGAGLFPHLTVGDNIGIVPRLLKWDKNRVA
MUL_0033|M.ulcerans_Agy99 DVTRRNPD--ELRRHIGYVVQGAGVFLHLTVGDNIGIVPRLLKWDKNRVA
MAV_0140|M.avium_104 AVRG-------IDPRCAVVFQEPRLLPWRSLAANVAFGLPRGTERPER-T
TH_3667|M.thermoresistible__bu TLAGGGAPVPAHRRRVGLMPQEGALFPHLSVAENIAFGLRR-TRRAGR-A
Mb1270|M.bovis_AF2122/97 RVNEKAPK----DRDIAMVFQSYALYPHMTVRQNIAFPLTLAKMRKADIA
Rv1238|M.tuberculosis_H37Rv RVNEKAPK----DRDIAMVFQSYALYPHMTVRQNIAFPLTLAKMRKADIA
MLBr_01089|M.leprae_Br4923 RVNEKAPK----DRDIAMVFQSYALYPHMTVRQNIAFPLMLAKVKKAEIA
. : * : :: *: : .
Mvan_0123|M.vanbaalenii_PYR-1 ERREELLGRVGLEGTADRR--IWEISGGQQQRVAIARALAAETPLFLLDE
Mflv_0722|M.gilvum_PYR-GCK ERRDELLERVGLGGTAGRR--IWEISGGQQQRVAIARALAAETPLFLLDE
MAB_2178|M.abscessus_ATCC_1997 QRRDQLLARVGLEGTAGRR--IWEISGGQQQRVAIARALAAETPLFLLDE
MSMEG_0116|M.smegmatis_MC2_155 ERRTQLLERVGLEGTEKRK--IWEISGGQQQRVAIARALAAETPLFLLDE
MMAR_0034|M.marinum_M ARIDELLDLVNLDPAQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDE
MUL_0033|M.ulcerans_Agy99 ARIDELLDLVNLDPAQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDE
MAV_0140|M.avium_104 AAVQRWLDVVGLREFAGHY--PRQVSGGMAQRAGLARALARQPSVLLLDE
TH_3667|M.thermoresistible__bu DTVRYWLEVVGLEGAAEAR--PHELSGGQQQRVALARALAAEPRVLLLDE
Mb1270|M.bovis_AF2122/97 QKVSETAKILDLTNLLDRK--PSQLSGGQRQRVAMGRAIVRHPKAFLMDE
Rv1238|M.tuberculosis_H37Rv QKVSETAKILDLTNLLDRK--PSQLSGGQRQRVAMGRAIVRHPKAFLMDE
MLBr_01089|M.leprae_Br4923 QKVSETAQILDLTDLLDRK--PSQLSGGQRQRVAMGRAIVRHPKAFLMDE
:.* ::*** **..:.**:. .. :*:**
Mvan_0123|M.vanbaalenii_PYR-1 PFAALDALTRERLQEDVRQVSAESGRTTVFVTHSADEAAFLGSRIVVLTR
Mflv_0722|M.gilvum_PYR-GCK PFAALDALTRERLQEDVRQVSAESGRTTVFVTHSADEAAFLGSRIVVLTR
MAB_2178|M.abscessus_ATCC_1997 PFAALDALTRERLQEDVRQVSAESGRTTVFVTHSADEAAFLGSRIVVLTR
MSMEG_0116|M.smegmatis_MC2_155 PFAALDALTRERLQEDVRQVSADSGRTTVFVTHSADEAAFLGSRIVVLTR
MMAR_0034|M.marinum_M PFGAVDPITRQRLQDELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTT
MUL_0033|M.ulcerans_Agy99 PFGAVDPITRQRLQDELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTT
MAV_0140|M.avium_104 PLAALDALTRLRMQDLLDAVQQRAGTTTILVTHDVEEAVLLADRVLILRG
TH_3667|M.thermoresistible__bu PFVALDAGLRVRVREEIAAILRAAGTTAVLVTHDQSEALSLADSVALLMD
Mb1270|M.bovis_AF2122/97 PLSNLDAKLRVQMRGEIAQLQRRLGTTTVYVTHDQTEAMTLGDRVVVMYG
Rv1238|M.tuberculosis_H37Rv PLSNLDAKLRVQMRGEIAQLQRRLGTTTVYVTHDQTEAMTLGDRVVVMYG
MLBr_01089|M.leprae_Br4923 PLSNLDAKLRVRTRGEIARLQRRLGATTVYVTHDQTEAMTLGDRVVVMRS
*: :*. * : : : : * : ***. ** *.. : ::
Mvan_0123|M.vanbaalenii_PYR-1 --------RPGQVALDIPVDLPRTGVDPDELRRSPEYGQLR---------
Mflv_0722|M.gilvum_PYR-GCK --------RPGQIALDIPVDLPRTGVDPEELRRSPEYGELR---------
MAB_2178|M.abscessus_ATCC_1997 --------RPGQVALDIPVDLPRTGIDPDDLRRSPEYAQLR---------
MSMEG_0116|M.smegmatis_MC2_155 --------RPGKVALDLPVDLPRTGVDPQELRRSPEFHRLR---------
MMAR_0034|M.marinum_M GSKVVQYDTPERILAEPANDFVRGFVGAGATLMQLSLTRVRD--------
MUL_0033|M.ulcerans_Agy99 GSKVVQYDTPERVLAEPANDFVRGFVGAGATLMQLSLTRVRD--------
MAV_0140|M.avium_104 -----------------------------------EEGGAAT--------
TH_3667|M.thermoresistible__bu GRLAQVGAPADIYERPATPAAARFVGATVELPGQARDGVVHT--------
Mb1270|M.bovis_AF2122/97 GIAQQIGTPEELYERPANLFVAGFIGSPAMNFFPARLTAIGLTLPFGEVT
Rv1238|M.tuberculosis_H37Rv GIAQQIGTPEELYERPANLFVAGFIGSPAMNFFPARLTAIGLTLPFGEVT
MLBr_01089|M.leprae_Br4923 GVVQQIGTPDELYERPVNLFVAGFIGSPVMNFFPAKLTPNGLTLPLGELN
Mvan_0123|M.vanbaalenii_PYR-1 --AEVGRAVKAAAA------------------------------------
Mflv_0722|M.gilvum_PYR-GCK --AEVGAAVRRAAA------------------------------------
MAB_2178|M.abscessus_ATCC_1997 --TEVGRAVKAAAA------------------------------------
MSMEG_0116|M.smegmatis_MC2_155 --TEVGEAVKAAAA------------------------------------
MMAR_0034|M.marinum_M --IDLHEAVVAQAGGDPAEAVELAGSLDREHAIVLDRQNRPLRWLPLEEL
MUL_0033|M.ulcerans_Agy99 --IDLHEAVVAQAGGDPAEAVELAGSLDRAHAIVLDRQNRPLRWLPLEEL
MAV_0140|M.avium_104 --VAATHDVAIPKP--------------------RDRGDPRIAALR----
TH_3667|M.thermoresistible__bu --ALGSHPARLPVPDGPVVVVLRPEELR----LERSRDGVPAAAVQSVRF
Mb1270|M.bovis_AF2122/97 LAPEVQGVIAAHPKPENVIVGVRPEHIQDAALIDAYQRIRALTFQVKVNL
Rv1238|M.tuberculosis_H37Rv LAPEVQGVIAAHPKPENVIVGVRPEHIQDAALIDAYQRIRALTFQVKVNL
MLBr_01089|M.leprae_Br4923 LSRDVQAMIGQHPVPDRVIVGVRPEHLTDAKLIDAHQHGTVLTFKVKVDL
Mvan_0123|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0722|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2178|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0116|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0034|M.marinum_M AKPQALAQVTRDDDLECVNLASTLNDALDEMLTSSHGVVVVTGRRNTYQG
MUL_0033|M.ulcerans_Agy99 AKPQALAQVTRDDDLECVNLASTLNDALDEMLTSAHGVVVVTGRRNTYQG
MAV_0140|M.avium_104 ------------------------------------------EQLLEEVG
TH_3667|M.thermoresistible__bu YGPQSAVQVRLADDTVVTVLTAGD----------------AGVSVGEPVG
Mb1270|M.bovis_AF2122/97 VESLGADKYLYFTTESPAVHSVQLDELAEVEGESALHENQFVARVPAESK
Rv1238|M.tuberculosis_H37Rv VESLGADKYLYFTTESPAVHSVQLDELAEVEGESALHENQFVARVPAESK
MLBr_01089|M.leprae_Br4923 VESLGADKYIYFTTTGCDVYSAQLDELAS---ELEVRENQFVARVSAESK
Mvan_0123|M.vanbaalenii_PYR-1 -----------------------------------
Mflv_0722|M.gilvum_PYR-GCK -----------------------------------
MAB_2178|M.abscessus_ATCC_1997 -----------------------------------
MSMEG_0116|M.smegmatis_MC2_155 -----------------------------------
MMAR_0034|M.marinum_M VIRVETIMEAIADIRGAANSEEPDT----------
MUL_0033|M.ulcerans_Agy99 VIRVETIMEAIADIRGAANSEEPDT----------
MAV_0140|M.avium_104 VPRRGYAIEQEAKTS--------------------
TH_3667|M.thermoresistible__bu VRVDGSVLAYPAPGRPPARS---------------
Mb1270|M.bovis_AF2122/97 VAIGQSVELAFDTARLAVFDADSGANLTIPHRA--
Rv1238|M.tuberculosis_H37Rv VAIGQSVELAFDTARLAVFDADSGANLTIPHRA--
MLBr_01089|M.leprae_Br4923 MAIGESIELAFGTAKIAVFDADSGVNLTVSAPTDA