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SSQSDTEPVAPQRRSGAIQIRSVSHRYGQGRDEVTALGPVDLTVEPGSFLVLVGASGCGKSTLLRLLAGF ESPTDGSVDVEGVPPTPGVTAGVVFQQPRLFPWRTVGGNVELALKYAKVPRDKRSERRDELLERVGLGGT AGRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSAESGRTTVFVTHSADE AAFLGSRIVVLTRRPGQIALDIPVDLPRTGVDPEELRRSPEYGELRAEVGAAVRRAAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0722 | - | - | 100% (269) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_1083 | - | 1e-38 | 42.98% (228) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_3158 | - | 2e-38 | 41.60% (250) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 5e-35 | 43.60% (211) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 5e-35 | 43.60% (211) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 2e-31 | 35.71% (210) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2178 | - | 1e-122 | 81.44% (264) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_3715 | cysA1 | 3e-36 | 42.67% (225) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_0140 | - | 3e-39 | 42.06% (214) | ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit |
| M. smegmatis MC2 155 | MSMEG_0116 | - | 1e-119 | 79.93% (269) | taurine import ATP-binding protein TauB |
| M. thermoresistible (build 8) | TH_2424 | - | 1e-36 | 44.55% (211) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 8e-36 | 44.55% (211) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_0123 | - | 1e-125 | 87.60% (258) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0722|M.gilvum_PYR-GCK MSSQSDTEPVAPQRRSGAIQIRSVSHRYGQGRDEVTALGPVDLTVEPGSF
Mvan_0123|M.vanbaalenii_PYR-1 MPSTND----------GAIRIDSVSHHYGSGGAEVTALGPVDLTVDPGSF
MAB_2178|M.abscessus_ATCC_1997 MPLVDEAETAVQERDTGSIRISGVTHSYGSGAGKTTALGPVDLTVEPGTF
MSMEG_0116|M.smegmatis_MC2_155 MPSASEAGPG----AEGELRIRNVAHRYGRGPNEVTALGPVDLDVEPGAF
MAV_0140|M.avium_104 ------------------------------------MLRDVDVEIEPGAV
Mb2419c|M.bovis_AF2122/97 --------MT------YAIVVADATKRYG----DFVALDHVDFVVPTGSL
Rv2397c|M.tuberculosis_H37Rv --------MT------YAIVVADATKRYG----DFVALDHVDFVVPTGSL
MMAR_3715|M.marinum_M --MKKETSLTGPGTGGHAIVVRDAFKQYG----DFVALDHVDFVVPAGSL
MUL_3658|M.ulcerans_Agy99 --------MTGPGTGGHAIVVRDAFKQYG----DFVALDHVDFVVPAGSL
TH_2424|M.thermoresistible__bu --------MT------DAITVRGANKRYG----DFAALDNVDFAVPAGSL
MLBr_01089|M.leprae_Br4923 ---------------MAEIVLEHVNKNYPN---GATAVHDLSITVADGEF
: :.. : * .
Mflv_0722|M.gilvum_PYR-GCK LVLVGASGCGKSTLLRLLAGFESPTDGSVDVEGVPPTPGVT----AGVVF
Mvan_0123|M.vanbaalenii_PYR-1 LVLVGASGCGKSTLLRLLAGFEEPSQGSVQVAGARPTPGVT----AGVVF
MAB_2178|M.abscessus_ATCC_1997 LVLVGASGCGKSTLLRLLAGFESPSEGAVRVAGGVPTPGIT----SGVVF
MSMEG_0116|M.smegmatis_MC2_155 VVLVGASGCGKSTLLRLIAGFETPTEGEVVVAGSRPTPGVT----SGVVF
MAV_0140|M.avium_104 VALLGASGSGKSTLLRLVAGLDRPSGGRIEIDG-KAVRGIDPR--CAVVF
Mb2419c|M.bovis_AF2122/97 TALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVF
Rv2397c|M.tuberculosis_H37Rv TALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVF
MMAR_3715|M.marinum_M TALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVF
MUL_3658|M.ulcerans_Agy99 TALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVF
TH_2424|M.thermoresistible__bu TALLGPSGSGKSTLLRAIAGLDRPDTGTITINGRDVTDVPPQRRGIGFVF
MLBr_01089|M.leprae_Br4923 LILIGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKDRDIAMVF
*:*.**.**:* *. :**:: * : : * ..**
Mflv_0722|M.gilvum_PYR-GCK QQPRLFPWRTVGGNVELALKYAKVPRDKRSERRDELLERVGLGGTAGRRI
Mvan_0123|M.vanbaalenii_PYR-1 QQPRLFPWRTVGGNVDMALRYAKVPRDKRIERREELLGRVGLEGTADRRI
MAB_2178|M.abscessus_ATCC_1997 QQPRLFPWRTVGGNIELALKYAKVPRERWAQRRDQLLARVGLEGTAGRRI
MSMEG_0116|M.smegmatis_MC2_155 QQPRLFPWRTVGGNIDLALKYAKVPRERRAERRTQLLERVGLEGTEKRKI
MAV_0140|M.avium_104 QEPRLLPWRSLAANVAFGLPRGTE-RPERTAAVQRWLDVVGLREFAGHYP
Mb2419c|M.bovis_AF2122/97 QHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYP
Rv2397c|M.tuberculosis_H37Rv QHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYP
MMAR_3715|M.marinum_M QHYAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYP
MUL_3658|M.ulcerans_Agy99 QHYAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYP
TH_2424|M.thermoresistible__bu QHYAAFKHLTVRDNVAFGLKIRRRPKREIAEKVDNLLEVVGLAGFQNRYP
MLBr_01089|M.leprae_Br4923 QSYALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTDLLDRKP
* :: *: * : . . :.* :
Mflv_0722|M.gilvum_PYR-GCK WEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSA
Mvan_0123|M.vanbaalenii_PYR-1 WEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSA
MAB_2178|M.abscessus_ATCC_1997 WEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSA
MSMEG_0116|M.smegmatis_MC2_155 WEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSA
MAV_0140|M.avium_104 RQVSGGMAQRAGLARALARQPSVLLLDEPLAALDALTRLRMQDLLDAVQQ
Mb2419c|M.bovis_AF2122/97 NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHD
Rv2397c|M.tuberculosis_H37Rv NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHD
MMAR_3715|M.marinum_M NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHD
MUL_3658|M.ulcerans_Agy99 DQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHD
TH_2424|M.thermoresistible__bu NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRTWLRRLHE
MLBr_01089|M.leprae_Br4923 SQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQR
::*** ** .:.**:. .. :*:***:. *** * : : :
Mflv_0722|M.gilvum_PYR-GCK ESGRTTVFVTHSADEAAFLGSRIVVLTRRPG-------------------
Mvan_0123|M.vanbaalenii_PYR-1 ESGRTTVFVTHSADEAAFLGSRIVVLTRRPG-------------------
MAB_2178|M.abscessus_ATCC_1997 ESGRTTVFVTHSADEAAFLGSRIVVLTRRPG-------------------
MSMEG_0116|M.smegmatis_MC2_155 DSGRTTVFVTHSADEAAFLGSRIVVLTRRPG-------------------
MAV_0140|M.avium_104 RAGTTTILVTHDVEEAVLLADRVLILRGEEGGAA----------------
Mb2419c|M.bovis_AF2122/97 EVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVM
Rv2397c|M.tuberculosis_H37Rv EVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVM
MMAR_3715|M.marinum_M EVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAFVM
MUL_3658|M.ulcerans_Agy99 EVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVM
TH_2424|M.thermoresistible__bu EVHVTTVLVTHDQSEALDVADRIAVLNNGRIEQVGSPAEVYDSPANEFVM
MLBr_01089|M.leprae_Br4923 RLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLFVA
**: ***. ** :..*: ::
Mflv_0722|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0123|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2178|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0116|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0140|M.avium_104 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 SFLGAVST------------------LNGSLVRPHDIRVGRTPNMAVAAA
Rv2397c|M.tuberculosis_H37Rv SFLGAVST------------------LNGSLVRPHDIRVGRTPNMAVAAA
MMAR_3715|M.marinum_M SFLGAVSA------------------LNGALVRPHDIRVGRTPEMAVAAA
MUL_3658|M.ulcerans_Agy99 SFLGAVSA------------------LNGALVRPHDIRVGRTPEMAVAAA
TH_2424|M.thermoresistible__bu SFLGAVSS------------------LNGTLVRPHDIWVGRHPELPTS--
MLBr_01089|M.leprae_Br4923 GFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIVGV
Mflv_0722|M.gilvum_PYR-GCK ----------------------QIALDIPVDL--------PRTGVDPEEL
Mvan_0123|M.vanbaalenii_PYR-1 ----------------------QVALDIPVDL--------PRTGVDPDEL
MAB_2178|M.abscessus_ATCC_1997 ----------------------QVALDIPVDL--------PRTGIDPDDL
MSMEG_0116|M.smegmatis_MC2_155 ----------------------KVALDLPVDL--------PRTGVDPQEL
MAV_0140|M.avium_104 ----------------------TVAATHDVAI--------PKP-RDRGDP
Mb2419c|M.bovis_AF2122/97 DGTAGSTGVLRAVVDRVVVLGFEVRVELTSAA--------TGGAFTAQIT
Rv2397c|M.tuberculosis_H37Rv DGTAGSTGVLRAVVDRVVVLGFEVRVELTSAA--------TGGAFTAQIT
MMAR_3715|M.marinum_M DGTGESTGVTRAVVDRIVVLGFEVRVELTSAA--------TGGAFTAQIT
MUL_3658|M.ulcerans_Agy99 DGTGESTGVTRAVVDRIVVLGFEVRVELTSAA--------TGGAFTAQIT
TH_2424|M.thermoresistible__bu DSTLQATGVVRARIDRVVMLGFEVRLELTSAT--------NNAPFTAQIT
MLBr_01089|M.leprae_Br4923 RPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVYSA
:
Mflv_0722|M.gilvum_PYR-GCK RRSPEYGELRAEVGAAVRRAAA----------------------------
Mvan_0123|M.vanbaalenii_PYR-1 RRSPEYGQLRAEVGRAVKAAAA----------------------------
MAB_2178|M.abscessus_ATCC_1997 RRSPEYAQLRTEVGRAVKAAAA----------------------------
MSMEG_0116|M.smegmatis_MC2_155 RRSPEFHRLRTEVGEAVKAAAA----------------------------
MAV_0140|M.avium_104 RIAALREQLLEEVGVPRRGYAIEQEAKTS---------------------
Mb2419c|M.bovis_AF2122/97 RGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST-----
Rv2397c|M.tuberculosis_H37Rv RGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST-----
MMAR_3715|M.marinum_M RGDAEALALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPSAAQIGVGG
MUL_3658|M.ulcerans_Agy99 RGDAEALALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGG
TH_2424|M.thermoresistible__bu RGDAEALGLRSGDTVYVRATRVPALP--TGDVDERVAAR-----------
MLBr_01089|M.leprae_Br4923 QLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGV
: *
Mflv_0722|M.gilvum_PYR-GCK ----------
Mvan_0123|M.vanbaalenii_PYR-1 ----------
MAB_2178|M.abscessus_ATCC_1997 ----------
MSMEG_0116|M.smegmatis_MC2_155 ----------
MAV_0140|M.avium_104 ----------
Mb2419c|M.bovis_AF2122/97 ----------
Rv2397c|M.tuberculosis_H37Rv ----------
MMAR_3715|M.marinum_M Q---------
MUL_3658|M.ulcerans_Agy99 Q---------
TH_2424|M.thermoresistible__bu ----------
MLBr_01089|M.leprae_Br4923 NLTVSAPTDA