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VPSASEAGPGAEGELRIRNVAHRYGRGPNEVTALGPVDLDVEPGAFVVLVGASGCGKSTLLRLIAGFETP TEGEVVVAGSRPTPGVTSGVVFQQPRLFPWRTVGGNIDLALKYAKVPRERRAERRTQLLERVGLEGTEKR KIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSADSGRTTVFVTHSADEAAF LGSRIVVLTRRPGKVALDLPVDLPRTGVDPQELRRSPEFHRLRTEVGEAVKAAAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0116 | - | - | 100% (265) | taurine import ATP-binding protein TauB |
| M. smegmatis MC2 155 | MSMEG_1160 | - | 2e-53 | 45.12% (246) | ABC-type nitrate/sulfonate/bicarbonate transport system ATPase |
| M. smegmatis MC2 155 | MSMEG_2633 | - | 5e-45 | 43.04% (237) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 7e-32 | 41.26% (206) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_0722 | - | 1e-120 | 79.93% (269) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 7e-32 | 41.26% (206) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 2e-32 | 37.32% (209) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2178 | - | 1e-119 | 84.19% (253) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0034 | proV_1 | 8e-37 | 38.82% (237) | osmoprotectant (glycine |
| M. avium 104 | MAV_0140 | - | 3e-38 | 41.55% (219) | ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit |
| M. thermoresistible (build 8) | TH_4520 | - | 9e-37 | 37.55% (237) | PUTATIVE osmoprotectant (glycine |
| M. ulcerans Agy99 | MUL_0033 | proV_1 | 2e-35 | 37.97% (237) | osmoprotectant (glycine |
| M. vanbaalenii PYR-1 | Mvan_0123 | - | 1e-119 | 83.07% (254) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ------------------MTYAIVVADATKRYG----DFVALDHVDFVVP
Rv2397c|M.tuberculosis_H37Rv ------------------MTYAIVVADATKRYG----DFVALDHVDFVVP
MAV_0140|M.avium_104 ----------------------------------------MLRDVDVEIE
Mflv_0722|M.gilvum_PYR-GCK ----MSSQSDTEPVAPQRRSGAIQIRSVSHRYGQGRDEVTALGPVDLTVE
Mvan_0123|M.vanbaalenii_PYR-1 ----MPSTND----------GAIRIDSVSHHYGSGGAEVTALGPVDLTVD
MAB_2178|M.abscessus_ATCC_1997 ----MPLVDEAETAVQERDTGSIRISGVTHSYGSGAGKTTALGPVDLTVE
MSMEG_0116|M.smegmatis_MC2_155 ----MPSASEAGPG----AEGELRIRNVAHRYGRGPNEVTALGPVDLDVE
MMAR_0034|M.marinum_M MPEAASADQPTTSDAPQSSGLRILLDGVTKRYG--VRSTPAVDNVTLEIG
MUL_0033|M.ulcerans_Agy99 MPEAASADQPTTSDAPQSSGLRILLDGVTKRYG--VRSTPAVDNVTLEIG
TH_4520|M.thermoresistible__bu ------VSEP-TSDLQSGGGARILLDGVTKRYD--PKSPPAVDNITMEIP
MLBr_01089|M.leprae_Br4923 -------------------MAEIVLEHVNKNYP---NGATAVHDLSITVA
: : . :
Mb2419c|M.bovis_AF2122/97 TGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR--R
Rv2397c|M.tuberculosis_H37Rv TGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR--R
MAV_0140|M.avium_104 PGAVVALLGASGSGKSTLLRLVAGLDRPSGGRIEIDGKAVRGIDPR----
Mflv_0722|M.gilvum_PYR-GCK PGSFLVLVGASGCGKSTLLRLLAGFESPTDGSVDVEGVPPTPG------V
Mvan_0123|M.vanbaalenii_PYR-1 PGSFLVLVGASGCGKSTLLRLLAGFEEPSQGSVQVAGARPTPG------V
MAB_2178|M.abscessus_ATCC_1997 PGTFLVLVGASGCGKSTLLRLLAGFESPSEGAVRVAGGVPTPG------I
MSMEG_0116|M.smegmatis_MC2_155 PGAFVVLVGASGCGKSTLLRLIAGFETPTEGEVVVAGSRPTPG------V
MMAR_0034|M.marinum_M AGEIVMLVGPSGCGKTTTMKMINRLIEPTSGRIFIGDDDVTRRNPDELRR
MUL_0033|M.ulcerans_Agy99 AGEIVMLVGPSGCGKTTTMKVINRLIEPTSGRIFIGDDDVTRRNPDELRR
TH_4520|M.thermoresistible__bu AGEIVMLVGPSGCGKTTTMKMINRLIEPTSGRIFIGDDDVTERDADELRR
MLBr_01089|M.leprae_Br4923 DGEFLILIGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKD--R
* . *:*.**.**:* :. : : * : : .
Mb2419c|M.bovis_AF2122/97 GIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSG
Rv2397c|M.tuberculosis_H37Rv GIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSG
MAV_0140|M.avium_104 -CAVVFQEPRLLPWRSLAANVAFGLP-RGTERPERTAAVQRWLDVVGLRE
Mflv_0722|M.gilvum_PYR-GCK TAGVVFQQPRLFPWRTVGGNVELALKYAKVPRDKRSERRDELLERVGLGG
Mvan_0123|M.vanbaalenii_PYR-1 TAGVVFQQPRLFPWRTVGGNVDMALRYAKVPRDKRIERREELLGRVGLEG
MAB_2178|M.abscessus_ATCC_1997 TSGVVFQQPRLFPWRTVGGNIELALKYAKVPRERWAQRRDQLLARVGLEG
MSMEG_0116|M.smegmatis_MC2_155 TSGVVFQQPRLFPWRTVGGNIDLALKYAKVPRERRAERRTQLLERVGLEG
MMAR_0034|M.marinum_M HIGYVVQGAGLFPHLTVGDNIGIVPRLLKWDKNRVAARIDELLDLVNLDP
MUL_0033|M.ulcerans_Agy99 HIGYVVQGAGVFLHLTVGDNIGIVPRLLKWDKNRVAARIDELLDLVNLDP
TH_4520|M.thermoresistible__bu HIGYVIQGAGLFPHYTVAENIAIVPRLLKWDRKRIAARVDELLDLVSLDP
MLBr_01089|M.leprae_Br4923 DIAMVFQSYALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTD
. *.* :: *: : : . . :.*
Mb2419c|M.bovis_AF2122/97 --FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELR
Rv2397c|M.tuberculosis_H37Rv --FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELR
MAV_0140|M.avium_104 --FAGHYPRQVSGGMAQRAGLARALARQPSVLLLDEPLAALDALTRLRMQ
Mflv_0722|M.gilvum_PYR-GCK --TAGRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQ
Mvan_0123|M.vanbaalenii_PYR-1 --TADRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQ
MAB_2178|M.abscessus_ATCC_1997 --TAGRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQ
MSMEG_0116|M.smegmatis_MC2_155 --TEKRKIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQ
MMAR_0034|M.marinum_M AQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQRLQ
MUL_0033|M.ulcerans_Agy99 AQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQRLQ
TH_4520|M.thermoresistible__bu DEYRDRYPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQRLQ
MLBr_01089|M.leprae_Br4923 --LLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTR
: ::*** ** .:.**:. .. :*:***:. :*. * . :
Mb2419c|M.bovis_AF2122/97 AWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKG-RIEQVGSPTDVY
Rv2397c|M.tuberculosis_H37Rv AWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKG-RIEQVGSPTDVY
MAV_0140|M.avium_104 DLLDAVQQRAGTTTILVTHDVEEAVLLADRVLILRG----EEGGAAT---
Mflv_0722|M.gilvum_PYR-GCK EDVRQVSAESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQIALDIPVDLP
Mvan_0123|M.vanbaalenii_PYR-1 EDVRQVSAESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQVALDIPVDLP
MAB_2178|M.abscessus_ATCC_1997 EDVRQVSAESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQVALDIPVDLP
MSMEG_0116|M.smegmatis_MC2_155 EDVRQVSADSGRTTVFVTHSADEAAFLGSRIVVLTRRPGKVALDLPVDLP
MMAR_0034|M.marinum_M DELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTTGSKVVQYDTPERIL
MUL_0033|M.ulcerans_Agy99 DELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTTGSKVVQYDTPERVL
TH_4520|M.thermoresistible__bu DELLRLQDELRKTIVFVTHDFDEAVKLGDRIAILQQGSKVVQYDTPEEIL
MLBr_01089|M.leprae_Br4923 GEIARLQRRLGATTVYVTHDQTEAMTLGDRVVVMRSG-VVQQIGTPDELY
: : * : ***. ** :..*: :: . .
Mb2419c|M.bovis_AF2122/97 DAPANAFVMSFLG-----------------------------AVSTLNGS
Rv2397c|M.tuberculosis_H37Rv DAPANAFVMSFLG-----------------------------AVSTLNGS
MAV_0140|M.avium_104 --------------------------------------------------
Mflv_0722|M.gilvum_PYR-GCK RTGVD-------------------------------------PEELRRSP
Mvan_0123|M.vanbaalenii_PYR-1 RTGVD-------------------------------------PDELRRSP
MAB_2178|M.abscessus_ATCC_1997 RTGID-------------------------------------PDDLRRSP
MSMEG_0116|M.smegmatis_MC2_155 RTGVD-------------------------------------PQELRRSP
MMAR_0034|M.marinum_M AEPANDFVRGFVGAGAT--------------------LMQLSLTRVRDID
MUL_0033|M.ulcerans_Agy99 AEPANDFVRGFVGAGAT--------------------LMQLSLTRVRDID
TH_4520|M.thermoresistible__bu TNPADDFVKGFVGHGAA--------------------LKQLTLTRVRDVD
MLBr_01089|M.leprae_Br4923 ERPVNLFVAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHP
Mb2419c|M.bovis_AF2122/97 LVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVV------------
Rv2397c|M.tuberculosis_H37Rv LVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVV------------
MAV_0140|M.avium_104 VAATHDVAIPKPR-------------------------------------
Mflv_0722|M.gilvum_PYR-GCK EYGELRAEVG----AAVRRAAA----------------------------
Mvan_0123|M.vanbaalenii_PYR-1 EYGQLRAEVG----RAVKAAAA----------------------------
MAB_2178|M.abscessus_ATCC_1997 EYAQLRTEVG----RAVKAAAA----------------------------
MSMEG_0116|M.smegmatis_MC2_155 EFHRLRTEVG----EAVKAAAA----------------------------
MMAR_0034|M.marinum_M LHEAVVAQAGGDPAEAVELAGSLDREHAIVLDRQNRPLRWLPLEELAKPQ
MUL_0033|M.ulcerans_Agy99 LHEAVVAQAGGDPAEAVELAGSLDRAHAIVLDRQNRPLRWLPLEELAKPQ
TH_4520|M.thermoresistible__bu LHDAVTARAGGDPDEAIHAARAADREHVIVLDAQNRPMRWMSLAELARPG
MLBr_01089|M.leprae_Br4923 VPDRVIVGVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFT
Mb2419c|M.bovis_AF2122/97 ----VLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRV
Rv2397c|M.tuberculosis_H37Rv ----VLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRV
MAV_0140|M.avium_104 ---------------------------DRGDPRIAALREQLLEEVGVPRR
Mflv_0722|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0123|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2178|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0116|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0034|M.marinum_M ALAQVTRDDDLECVNLASTLNDALDEMLTSSHGVVVVTGRRNTYQGVIRV
MUL_0033|M.ulcerans_Agy99 ALAQVTRDDDLECVNLASTLNDALDEMLTSAHGVVVVTGRRNTYQGVIRV
TH_4520|M.thermoresistible__bu ALIRVSRDENLECVTLASTLTDALDDMLTSSHGVVVVTGRRNTYQGVIRL
MLBr_01089|M.leprae_Br4923 TTGCDVYSAQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKI
Mb2419c|M.bovis_AF2122/97 PPIAGGVSGVDDAGVERVKVTST
Rv2397c|M.tuberculosis_H37Rv PPIAGGVSGVDDAGVERVKVTST
MAV_0140|M.avium_104 -----------GYAIEQEAKTS-
Mflv_0722|M.gilvum_PYR-GCK -----------------------
Mvan_0123|M.vanbaalenii_PYR-1 -----------------------
MAB_2178|M.abscessus_ATCC_1997 -----------------------
MSMEG_0116|M.smegmatis_MC2_155 -----------------------
MMAR_0034|M.marinum_M ETIMEAIADIRGAANSEEPDT--
MUL_0033|M.ulcerans_Agy99 ETIMEAIADIRGAANSEEPDT--
TH_4520|M.thermoresistible__bu ETIMDAIADARGTAGSQGAGAP-
MLBr_01089|M.leprae_Br4923 AVFDADSGVNLTVSAPTDA----