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VLRDVDVEIEPGAVVALLGASGSGKSTLLRLVAGLDRPSGGRIEIDGKAVRGIDPRCAVVFQEPRLLPWR SLAANVAFGLPRGTERPERTAAVQRWLDVVGLREFAGHYPRQVSGGMAQRAGLARALARQPSVLLLDEPL AALDALTRLRMQDLLDAVQQRAGTTTILVTHDVEEAVLLADRVLILRGEEGGAATVAATHDVAIPKPRDR GDPRIAALREQLLEEVGVPRRGYAIEQEAKTS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0140 | - | - | 100% (242) | ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit |
| M. avium 104 | MAV_2434 | - | 8e-44 | 46.98% (232) | putative aliphatic sulfonates transport ATP-binding protein |
| M. avium 104 | MAV_3398 | - | 4e-43 | 42.22% (225) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1890 | modC | 3e-38 | 41.30% (230) | molybdenum ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_3158 | - | 6e-51 | 51.30% (230) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1859 | modC | 3e-38 | 41.30% (230) | molybdenum ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01089 | - | 4e-31 | 35.24% (210) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2217 | - | 2e-42 | 46.96% (230) | sulfonate ABC transporter, ATP-binding subunit SsuB |
| M. marinum M | MMAR_3715 | cysA1 | 2e-36 | 45.77% (201) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. smegmatis MC2 155 | MSMEG_0551 | - | 5e-97 | 76.09% (230) | ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit |
| M. thermoresistible (build 8) | TH_3667 | - | 2e-41 | 46.41% (209) | PUTATIVE ferric cations import ATP-binding protein FbpC |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-36 | 45.77% (201) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_3412 | - | 3e-44 | 47.83% (230) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0140|M.avium_104 --------------------------------------------------
MSMEG_0551|M.smegmatis_MC2_155 ----------------------------MTSTDLAPARVSVRNVGRTFGT
MAB_2217|M.abscessus_ATCC_1997 -------------------MTAVFEVTELSPHS-TTAAAELTSVTKWYGR
Mvan_3412|M.vanbaalenii_PYR-1 -------------------MTTTSHAAERGTAAHTTAAGELRNVNKWYGV
Mflv_3158|M.gilvum_PYR-GCK ---------------------------------MSSPVVTVRGLHRAFGA
Mb1890|M.bovis_AF2122/97 ----------------------------MSKLQLRAVVADRR--------
Rv1859|M.tuberculosis_H37Rv ----------------------------MSKLQLRAVVADRR--------
TH_3667|M.thermoresistible__bu VIKTMKTKPADTSGAGPAVSNPAVSNPDVSAPQLRGADVEVQGLHKSFGA
MMAR_3715|M.marinum_M ----------------------MKKETSLTGPGTGGHAIVVRDAFKQYGD
MUL_3658|M.ulcerans_Agy99 ----------------------------MTGPGTGGHAIVVRDAFKQYGD
MLBr_01089|M.leprae_Br4923 ----------------------------------MAEIVLEHVNKNYPNG
MAV_0140|M.avium_104 --MLRDVDVEIEPGAVVALLGASGSGKSTLLRLVAGLDRPSGGRIEID--
MSMEG_0551|M.smegmatis_MC2_155 HTVLRDIDLEIEPGEVIALLGSSGSGKSTLLRLIAGLDLPTEGLIEID--
MAB_2217|M.abscessus_ATCC_1997 NRVLDDVSLRVGCGEIVALVGRSGSGKSTVLRVLSGLAGDHTGERKVL--
Mvan_3412|M.vanbaalenii_PYR-1 HHVLTDVSVRVACGEIVALIGRSGSGKSTVLRVLAGLSTDHTGDRAVA--
Mflv_3158|M.gilvum_PYR-GCK QQVLDDLDLDIAGGEFVAMLGRSGSGKSTLLRILAGLDNRADGSVLVP--
Mb1890|M.bovis_AF2122/97 ----LDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDR
Rv1859|M.tuberculosis_H37Rv ----LDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDR
TH_3667|M.thermoresistible__bu KAVLRGVDLTVSAGTLTAVLGPSGCGKTTLLRILAGFDDPDAGTVRIGGH
MMAR_3715|M.marinum_M FVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGNITINGR
MUL_3658|M.ulcerans_Agy99 FVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGNITINGR
MLBr_01089|M.leprae_Br4923 ATAVHDLSITVADGEFLILIGPSGCGKTTTLNMIAGLEDISSGELRIDGD
:.. : * . ::* .*.**:* *. ::*: * :
MAV_0140|M.avium_104 -------GKAVRGIDPRCAVVFQEPRLLPWRSLAANVAFGLPRG-----T
MSMEG_0551|M.smegmatis_MC2_155 -------GDAIRETDPRCAIVFQEPRLFPWRSLAGNVAYGLPRG-----T
MAB_2217|M.abscessus_ATCC_1997 -------GAP--------AVAFQEPRLFPWRSVRDNVLYGLTRTK----L
Mvan_3412|M.vanbaalenii_PYR-1 -------GAP--------ALAFQEPRLFPWRDVRTNVVYGLTRAR----L
Mflv_3158|M.gilvum_PYR-GCK -------RSR--------AVVFQNPRLLPWRRALANVTFALPQAG----P
Mb1890|M.bovis_AF2122/97 VLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGS
Rv1859|M.tuberculosis_H37Rv VLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGS
TH_3667|M.thermoresistible__bu TLAG--GGAPVPAHRRRVGLMPQEGALFPHLSVAENIAFGLRRTR-----
MMAR_3715|M.marinum_M ------DVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRK----R
MUL_3658|M.ulcerans_Agy99 ------DVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRK----R
MLBr_01089|M.leprae_Br4923 ------RVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLMLAK----V
.. * *: :
MAV_0140|M.avium_104 ERPERTAAVQRWLDVVGLREFAGHYPRQVSGGMAQRAGLARALARQPSVL
MSMEG_0551|M.smegmatis_MC2_155 SRTEGAETVRHWLEVVGLQEFADHRPRQVSGGMAQRAGLARALARRPRVL
MAB_2217|M.abscessus_ATCC_1997 SRDEALSRVDRALDEVGLADKAQAWPLTLSGGQAQRVSLARALVAEPQLL
Mvan_3412|M.vanbaalenii_PYR-1 TRAEAVARADRALADVGLSDRAAAWPLTLSGGQAQRVSLARALVAEPTLL
Mflv_3158|M.gilvum_PYR-GCK DAPSRTARGQAALDEVGLSGKARAWPLSLSGGEAQRVSLARALVREPDLL
Mb1890|M.bovis_AF2122/97 GRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVL
Rv1859|M.tuberculosis_H37Rv GRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVL
TH_3667|M.thermoresistible__bu -RAGRADTVRYWLEVVGLEGAAEARPHELSGGQQQRVALARALAAEPRVL
MMAR_3715|M.marinum_M PKAEIRDKVDNLLEVVGLSGFHGRYPNQLSGGQRQRMALARALAVDPEVL
MUL_3658|M.ulcerans_Agy99 PKAEIRDKVDNLLEVVGLSGFHGRYPDQLSGGQRQRMALARALAVDPEVL
MLBr_01089|M.leprae_Br4923 KKAEIAQKVSETAQILDLTDLLDRKPSQLSGGQRQRVAMGRAIVRHPKAF
:. * :*** ** .:.**:. * :
MAV_0140|M.avium_104 LLDEPLAALDALTRLRMQDLLDAVQQRAGTTTILVTHDVEEAVLLADRVL
MSMEG_0551|M.smegmatis_MC2_155 LLDEPLAALDALTRLQMQMLLDKVQQEAGTTTILVTHDVEEAVILADRVL
MAB_2217|M.abscessus_ATCC_1997 LLDEPFGALDALTRLSMHRLLLNLWEQHGFGVLLVTHDVDEAISLADTVL
Mvan_3412|M.vanbaalenii_PYR-1 LLDEPFGALDALTRLSMRTLLLDLWREHGFGVLLVTHDVDEAVALADRVV
Mflv_3158|M.gilvum_PYR-GCK LLDEPFGALDALTRLKMYRLLHDLWARRRMAVLHVTHDVDEAILLADRVV
Mb1890|M.bovis_AF2122/97 LLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVL
Rv1859|M.tuberculosis_H37Rv LLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVL
TH_3667|M.thermoresistible__bu LLDEPFVALDAGLRVRVREEIAAILRAAGTTAVLVTHDQSEALSLADSVA
MMAR_3715|M.marinum_M LLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIA
MUL_3658|M.ulcerans_Agy99 LLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIA
MLBr_01089|M.leprae_Br4923 LMDEPLSNLDAKLRVRTRGEIARLQRRLGATTVYVTHDQTEAMTLGDRVV
*:***: **. : : .: .*** :.. :.* :
MAV_0140|M.avium_104 ILRG-EEGGAATVAATHDVAIPKPRDRG--------------------DP
MSMEG_0551|M.smegmatis_MC2_155 LLRA-DNDGTAGLAASFDVTIPKPRDRG--------------------DP
MAB_2217|M.abscessus_ATCC_1997 VLD------EGRLAHTLRIRNPR-KPRGK------------------HDA
Mvan_3412|M.vanbaalenii_PYR-1 VLE------DGAVVHTLDIPDPR-RATG--------------------EG
Mflv_3158|M.gilvum_PYR-GCK VLS------DGAVSLDRRVDLPFPRSRG--------------------DD
Mb1890|M.bovis_AF2122/97 VLESGTIAEIGPVADVLTAPRSRFGARIAGV---------------NLVN
Rv1859|M.tuberculosis_H37Rv VLESGTIAEIGPVADVLTAPRSRFGARIAGV---------------NLVN
TH_3667|M.thermoresistible__bu LLMDGRLAQVGAPADIYERPATPAAARFVGA---------------TVEL
MMAR_3715|M.marinum_M VLNSGRIEQVGSPTEVYDAPANAFVMSFLG--------------------
MUL_3658|M.ulcerans_Agy99 VLNSGRIEQVGSPTEVYDAPTNAFVMSFLG--------------------
MLBr_01089|M.leprae_Br4923 VMRSGVVQQIGTPDELYERPVNLFVAGFIGSPVMNFFPAKLTPNGLTLPL
:: .
MAV_0140|M.avium_104 RIAALREQLLEEVGVPRRGYAIEQEAKTS---------------------
MSMEG_0551|M.smegmatis_MC2_155 RVIELRDLLLDELGVPR----TAPEAT-----------------------
MAB_2217|M.abscessus_ATCC_1997 ETENHRGELLAQLGV-----------------------------------
Mvan_3412|M.vanbaalenii_PYR-1 YTDRYRAELLDKLGVQI---------------------------------
Mflv_3158|M.gilvum_PYR-GCK GFDELRRELLAELGVKEEVGHDRSR-------------------------
Mb1890|M.bovis_AF2122/97 GTIGPDGSLRTQSGAHWYGTPVQDLPTGHEAIAVFPPTAVAVYPEPPHGS
Rv1859|M.tuberculosis_H37Rv GTIGPDGSLRTQSGAHWYGTPVQDLPTGHEAIAVFPPTAVAVYPEPPHGS
TH_3667|M.thermoresistible__bu PGQARDGVVHTALGSHPARLPVPDGP----VVVVLRPEELRLER-----S
MMAR_3715|M.marinum_M AVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRIVVLGF
MUL_3658|M.ulcerans_Agy99 AVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRIVVLGF
MLBr_01089|M.leprae_Br4923 GELNLSRDVQAMIGQHPVPDRVIVGVRPEHLTDAKLIDAHQHGTVLTFKV
: .
MAV_0140|M.avium_104 --------------------------------------------------
MSMEG_0551|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2217|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3412|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3158|M.gilvum_PYR-GCK --------------------------------------------------
Mb1890|M.bovis_AF2122/97 PRNIVGLTVAEVDTRGPMVLVRGHDQPGGAPGLAACIT-----VDAATEL
Rv1859|M.tuberculosis_H37Rv PRNIVGLTVAEVDTRGPTVLVRGHDQPGGAPGLAACIT-----VDAATEL
TH_3667|M.thermoresistible__bu RDGVPAAAVQSVRFYGPQSAVQVR------LADDTVVT-----VLTAGDA
MMAR_3715|M.marinum_M EVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVR-----ATRVPPI
MUL_3658|M.ulcerans_Agy99 EVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVR-----ATRVPPI
MLBr_01089|M.leprae_Br4923 KVDLVESLGADKYIYFTTTGCDVYSAQLDELASELEVRENQFVARVSAES
MAV_0140|M.avium_104 ------------------------------------
MSMEG_0551|M.smegmatis_MC2_155 ------------------------------------
MAB_2217|M.abscessus_ATCC_1997 ------------------------------------
Mvan_3412|M.vanbaalenii_PYR-1 ------------------------------------
Mflv_3158|M.gilvum_PYR-GCK ------------------------------------
Mb1890|M.bovis_AF2122/97 RVAPGSRVWFSVKAQEVALHPAPHQHASS-------
Rv1859|M.tuberculosis_H37Rv RVAPGSRVWFSVKAQEVALHPAPHQHASS-------
TH_3667|M.thermoresistible__bu GVSVGEPVGVRVDGSVLAYPAPGRPPARS-------
MMAR_3715|M.marinum_M AGAAPAVPDDGAGSTPSAAQIGVGGQ----------
MUL_3658|M.ulcerans_Agy99 AGAAPAVPDDGAGSTPRAAQIGVGGQ----------
MLBr_01089|M.leprae_Br4923 KMAIGESIELAFGTAKIAVFDADSGVNLTVSAPTDA