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PSAVRIESAGKSYGATVALDDVSLQIEPGQMVALLGPSGCGKTSLLRSIAGLSPLDSGTVRIGDVDVTHL PARHRPIGMVFQHYALFPNMSVAENISFPLAIRRERRAARDARVEELLALIGMSELADRYPNQLSGGQQQ RVALARALAPEPDVLLLDEPLAALDAAIRNDLRDEIRRIQHRVGTTAVFVTHDQSEAMAVADRVAVMDRG RILEVAAPAEIYERPTSRFTATFVGSRNALELPVDADRVVRWGQAFEVPAPTAANGKALAVFRPEDVRIT GRDGLPGTVDVVLFLGATSRIYLTVDGHTVHADLPSRAAAEYRPGQHVGVTVAADDVRVFAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5731 | - | - | 100% (343) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_5739 | - | 6e-86 | 50.15% (337) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3872 | - | 2e-68 | 45.36% (302) | sulfate ABC transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 5e-67 | 45.87% (303) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_1083 | - | 6e-84 | 50.30% (338) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 5e-67 | 45.87% (303) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01424 | - | 4e-61 | 41.16% (311) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_1655 | - | 8e-67 | 45.54% (303) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 2e-66 | 45.70% (302) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 1e-66 | 48.50% (266) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_6671 | - | 1e-159 | 83.00% (347) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_3667 | - | 9e-67 | 46.43% (336) | PUTATIVE ferric cations import ATP-binding protein FbpC |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-66 | 45.70% (302) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5731|M.vanbaalenii_PYR-1 ------MPS------------------------------AVRIESAGKSY
MSMEG_6671|M.smegmatis_MC2_155 ------MPS------------------------------AVQIESATKVY
Mflv_1083|M.gilvum_PYR-GCK ------MTNR---------------------------GVGVQFDELTRVY
TH_3667|M.thermoresistible__bu --VIKTMKTKPADTSGAGPAVSNPAVSNPDVSAPQLRGADVEVQGLHKSF
Mb2419c|M.bovis_AF2122/97 ------MT------------------------------YAIVVADATKRY
Rv2397c|M.tuberculosis_H37Rv ------MT------------------------------YAIVVADATKRY
MAV_1785|M.avium_104 ------MTDAGTD----------------------RGDIAITVRDAYKRY
MMAR_3715|M.marinum_M MKKETSLTGPG------------------------TGGHAIVVRDAFKQY
MUL_3658|M.ulcerans_Agy99 ------MTGPG------------------------TGGHAIVVRDAFKQY
MAB_1655|M.abscessus_ATCC_1997 ------MTAEN----------------------------TITVRGANKHY
MLBr_01424|M.leprae_Br4923 -------------------------------------MASVTFEQATRQF
: . : :
Mvan_5731|M.vanbaalenii_PYR-1 G--ATVALDDVSLQIEPGQMVALLGPSGCGKTSLLRSIAGLSPLDSGTVR
MSMEG_6671|M.smegmatis_MC2_155 G--STKALDNVSLHIDPGQMVALLGPSGCGKTSLLRAIAGLNPLDRGAIR
Mflv_1083|M.gilvum_PYR-GCK G--ATRALDGLTLHIEPGELVALLGPSGGGKTTALRILAGLDEATSGTVS
TH_3667|M.thermoresistible__bu G--AKAVLRGVDLTVSAGTLTAVLGPSGCGKTTLLRILAGFDDPDAGTVR
Mb2419c|M.bovis_AF2122/97 G--DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTIT
Rv2397c|M.tuberculosis_H37Rv G--DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTIT
MAV_1785|M.avium_104 G--DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTVT
MMAR_3715|M.marinum_M G--DFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGNIT
MUL_3658|M.ulcerans_Agy99 G--DFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGNIT
MAB_1655|M.abscessus_ATCC_1997 G--DFAALDNIDFDVPSGSLTALLGPSGSGKSTLLRSIAGLDNPDSGTIT
MLBr_01424|M.leprae_Br4923 PDTDRPALDRLDLDVDDGEFVVVVGPSGCGKTTSLRMVAGLETLDSGCIR
.* : : : * :..::**** **:: ** :**:. * :
Mvan_5731|M.vanbaalenii_PYR-1 IGDVDVT----HLPARHRPIGMVFQHYALFPNMSVAENISFPLAIRRERR
MSMEG_6671|M.smegmatis_MC2_155 IGESDVT----MVPARLRPIGMVFQHYALFPNMTVAENISFPLTINKQRR
Mflv_1083|M.gilvum_PYR-GCK VGGVDVG----RVPANKRDMGMVFQAYSLFPHLTVLDNVAFGLKMRGKGK
TH_3667|M.thermoresistible__bu IGGHTLAGGGAPVPAHRRRVGLMPQEGALFPHLSVAENIAFG--LRRTRR
Mb2419c|M.bovis_AF2122/97 INGRDVT----RVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPK
Rv2397c|M.tuberculosis_H37Rv INGRDVT----RVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPK
MAV_1785|M.avium_104 IYGRDVT----RVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKVRKRPK
MMAR_3715|M.marinum_M INGRDVT----RVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRKRPK
MUL_3658|M.ulcerans_Agy99 INGRDVT----RVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRKRPK
MAB_1655|M.abscessus_ATCC_1997 INGRDVT----GVPPQRRDIGFVFQHYAAFKHLTVWENVAFGLKIRKKPK
MLBr_01424|M.leprae_Br4923 IGDRDVT----HVDPKDRDVAMVFQNYALYPHMTVAQNLGFALKISKISK
: : : .. * :.:: * : : :::* :*:.: : :
Mvan_5731|M.vanbaalenii_PYR-1 AARDARVEELLALIGMSELADRYPNQLSGGQQQRVALARALAPEPDVLLL
MSMEG_6671|M.smegmatis_MC2_155 AERAQRVGELLELIGMTALADRYPNQLSGGQQQRVALARALAPEPDVLLL
Mflv_1083|M.gilvum_PYR-GCK SDRLSRAADMLDLVGLGELGGRYANELSGGQQQRVALARALAIRPRVLLL
TH_3667|M.thermoresistible__bu AGRADTVRYWLEVVGLEGAAEARPHELSGGQQQRVALARALAAEPRVLLL
Mb2419c|M.bovis_AF2122/97 AEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLL
Rv2397c|M.tuberculosis_H37Rv AEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLL
MAV_1785|M.avium_104 AEIKAKVDNLLEVVGLSGFQGRYPNQLSGGQRQRMALARALAVDPQVLLL
MMAR_3715|M.marinum_M AEIRDKVDNLLEVVGLSGFHGRYPNQLSGGQRQRMALARALAVDPEVLLL
MUL_3658|M.ulcerans_Agy99 AEIRDKVDNLLEVVGLSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLL
MAB_1655|M.abscessus_ATCC_1997 AEIKKKVDDLLEVVGLSGFHTRYPAQLSGGQRQRMALARALAVDPQVLLL
MLBr_01424|M.leprae_Br4923 AEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMGRAIVRRPQVFLM
: ::.: . :*****:**:*:.**:. * *:*:
Mvan_5731|M.vanbaalenii_PYR-1 DEPLAALDAAIRNDLRDEIRRIQHRVGTTAVFVTHDQSEAMAVADRVAVM
MSMEG_6671|M.smegmatis_MC2_155 DEPLAALDAAIRNDLRDEIRRIQHRVGTTAVFVTHDQSEAMAVADRVAVM
Mflv_1083|M.gilvum_PYR-GCK DEPLSALDAKVRTQLRDEIRRVQLEVGTTTLFVTHDQEEALAVADRVGVM
TH_3667|M.thermoresistible__bu DEPFVALDAGLRVRVREEIAAILRAAGTTAVLVTHDQSEALSLADSVALL
Mb2419c|M.bovis_AF2122/97 DEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVL
Rv2397c|M.tuberculosis_H37Rv DEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVL
MAV_1785|M.avium_104 DEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVL
MMAR_3715|M.marinum_M DEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVL
MUL_3658|M.ulcerans_Agy99 DEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVL
MAB_1655|M.abscessus_ATCC_1997 DEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVL
MLBr_01424|M.leprae_Br4923 DEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQVEAMTMGDRVAVL
***: *** :* * : : .*:: ***** **: :.* :.::
Mvan_5731|M.vanbaalenii_PYR-1 DRGRILEVAAPAEIYERPTSRFTATFVGS--RNALELPVDADRVVRWGQA
MSMEG_6671|M.smegmatis_MC2_155 DRGRILEVAAPPEIYERPTSRFAATFVGS--RNALELPVDADRVVRWGTA
Mflv_1083|M.gilvum_PYR-GCK NQGRLEQLAAPADLYAHPATPFVADFVGL--NNKVPASVSGGTATLLGVS
TH_3667|M.thermoresistible__bu MDGRLAQVGAPADIYERPATPAAARFVGA--TVELPGQARDG-VVHTALG
Mb2419c|M.bovis_AF2122/97 HKGRIEQVGSPTDVYDAPANAFVMSFLGA--VSTLNGSLVRPHDIRVGRT
Rv2397c|M.tuberculosis_H37Rv HKGRIEQVGSPTDVYDAPANAFVMSFLGA--VSTLNGSLVRPHDIRVGRT
MAV_1785|M.avium_104 NQGRIEQIGSPTEVYDAPTNAFVMSFLGA--VSTLNGTLVRPHDIRVGRT
MMAR_3715|M.marinum_M NSGRIEQVGSPTEVYDAPANAFVMSFLGA--VSALNGALVRPHDIRVGRT
MUL_3658|M.ulcerans_Agy99 NSGRIEQVGSPTEVYDAPTNAFVMSFLGA--VSALNGALVRPHDIRVGRT
MAB_1655|M.abscessus_ATCC_1997 NKGRIEQVGSPEDLYDRPANSFVMSFLGP--VAKLNGILVRPHDIRVGRN
MLBr_01424|M.leprae_Br4923 CYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLSIVDSSVLLGDWP
* : :..:* ::* * . . *:* :
Mvan_5731|M.vanbaalenii_PYR-1 FEVPAPTAA-NGKALAVFRPEDVRITG-----RDGLPGTVDVVLFLGATS
MSMEG_6671|M.smegmatis_MC2_155 FSVAAPDAA-NGKALAVFRPEDVRLTA-----HQGVAGTVDVVVFLGATS
Mflv_1083|M.gilvum_PYR-GCK VP-ALPGSV-DGDGVAMVRPEAVTVAA-----DPAGTATVATVSFLGAIT
TH_3667|M.thermoresistible__bu SHPARLPVP-DGPVVVVLRPEELRLERS---RDGVPAAAVQSVRFYGPQS
Mb2419c|M.bovis_AF2122/97 PNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQIT
Rv2397c|M.tuberculosis_H37Rv PNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQIT
MAV_1785|M.avium_104 PEMAVAAEDGTAESTGVARAIVDRVVKLGFEVRVELTSAATGGPFTAQIT
MMAR_3715|M.marinum_M PEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQIT
MUL_3658|M.ulcerans_Agy99 PEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQIT
MAB_1655|M.abscessus_ATCC_1997 ADLARAAAEGTGETTGVTKATVDRVVYLGFEVRVELTSAATGEQFTAQIT
MLBr_01424|M.leprae_Br4923 IRIPREIASAASEVIIGVRPEHFELGSLGVEVEIDMVEELGADAYLYGRI
. . :. : :
Mvan_5731|M.vanbaalenii_PYR-1 RIYLTVDG----HTVHADLPSRAAAEYRPGQHVGVTVAADDVRVFAS---
MSMEG_6671|M.smegmatis_MC2_155 RVYVTVEGEAGDHTVHVDLPSRAAANFVPGQRVGVVVAPEKVRVFAS---
Mflv_1083|M.gilvum_PYR-GCK RVGITMPD---GSLLSAQMSSTAARALTPGDPVTVGVEPGGVLVTRPL--
TH_3667|M.thermoresistible__bu AVQVRLAD----DTVVTVLTAGDAG-VSVGEPVGVRVDGSVLAYPAPGRP
Mb2419c|M.bovis_AF2122/97 RGDAEALALREGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVTST--
Rv2397c|M.tuberculosis_H37Rv RGDAEALALREGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVTST--
MAV_1785|M.avium_104 RGDAEALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA--
MMAR_3715|M.marinum_M RGDAEALALQEGDTVYVRATRVPPIAGA---APAVPDDGAGSTPSAAQIG
MUL_3658|M.ulcerans_Agy99 RGDAEALALQEGDTVYVRATRVPPIAGA---APAVPDDGAGSTPRAAQIG
MAB_1655|M.abscessus_ATCC_1997 RGDAEALGLREGDPVYVRVTRVP--------------DVGELAEVAS---
MLBr_01424|M.leprae_Br4923 AGASKVTDQLVVARVDGRNPPAKGSRVRLYTEPGNVHFFGVDGHRIS---
: . .
Mvan_5731|M.vanbaalenii_PYR-1 ----
MSMEG_6671|M.smegmatis_MC2_155 ----
Mflv_1083|M.gilvum_PYR-GCK ----
TH_3667|M.thermoresistible__bu PARS
Mb2419c|M.bovis_AF2122/97 ----
Rv2397c|M.tuberculosis_H37Rv ----
MAV_1785|M.avium_104 ----
MMAR_3715|M.marinum_M VGGQ
MUL_3658|M.ulcerans_Agy99 VGGQ
MAB_1655|M.abscessus_ATCC_1997 ----
MLBr_01424|M.leprae_Br4923 ----