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VNDRDDPATDQAAVTPEPPRPREMFRQPTRPLPPQPRRPDGWEQQQPPPGWAPQAPPSAPPYPPRPQADA PWTAPQPTSYAEWIRPADLVPHRKVVPGSGWRLALYKASFGLINLGPSPEDKRVAELEATIRTPLRGRFK IGVMGKGGVGKTTVSASIGSVLAEIRQDDRVVAVDADTAFGKLGSRVDPRAQGSFWELAADRHLEAFADI RNHLGCNAAGLFVLAGEATPARRRVLDPAIYREATTRLDRHFTISVIDCSSTMDSPVTQEVLRDLDALVV VSSPWVDGAAAAGQTLDWLAARGLTDLLQRTVVVLNDSDGHADKRTRGILAQQFSGHGQLVIEVPFDGHL RPGGVIDGTGEMSPSARRKFIEVVAALAAFFPASVTRSG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_0069 | - | - | 100% (390) | hypothetical protein Mvan_0069 |
M. vanbaalenii PYR-1 | Mvan_0080 | - | 8e-44 | 33.77% (379) | hypothetical protein Mvan_0080 |
M. vanbaalenii PYR-1 | Mvan_0870 | - | 3e-40 | 33.33% (342) | hypothetical protein Mvan_0870 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3890 | - | 1e-111 | 55.01% (369) | hypothetical protein Mb3890 |
M. gilvum PYR-GCK | Mflv_0776 | - | 1e-158 | 73.08% (390) | hypothetical protein Mflv_0776 |
M. tuberculosis H37Rv | Rv3860 | - | 1e-111 | 55.28% (369) | hypothetical protein Rv3860 |
M. leprae Br4923 | MLBr_00048 | - | 1e-44 | 31.05% (409) | hypothetical protein MLBr_00048 |
M. abscessus ATCC 19977 | MAB_0630 | - | 2e-48 | 33.75% (403) | hypothetical protein MAB_0630 |
M. marinum M | MMAR_5436 | - | 1e-116 | 56.73% (379) | hypothetical protein MMAR_5436 |
M. avium 104 | MAV_0163 | - | 1e-120 | 57.73% (388) | hypothetical protein MAV_0163 |
M. smegmatis MC2 155 | MSMEG_0053 | - | 1e-142 | 64.86% (407) | hypothetical protein MSMEG_0053 |
M. thermoresistible (build 8) | TH_0884 | - | 4e-43 | 34.90% (298) | conserved hypothetical protein |
M. ulcerans Agy99 | MUL_0202 | pra | 9e-05 | 29.69% (128) | proline-rich antigen Pra-like protein |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_0069|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_0776|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0053|M.smegmatis_MC2_155 -------------------------------------------------- Mb3890|M.bovis_AF2122/97 -------------------------------------------------- Rv3860|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5436|M.marinum_M -------------------------------------------------- MAV_0163|M.avium_104 -------------------------------------------------- MAB_0630|M.abscessus_ATCC_1997 MADTNDNAPDSPPPSGPWREPIADGLGGGDTKGSPFRRSKNSNQEFVPPS TH_0884|M.thermoresistible__bu -------------------------------------------------- MLBr_00048|M.leprae_Br4923 ---------------------MAADYDKLFRLDDGAYASPDQAAEQLFDD MUL_0202|M.ulcerans_Agy99 -------------------------------------------------- Mvan_0069|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_0776|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0053|M.smegmatis_MC2_155 -------------------------------------------------- Mb3890|M.bovis_AF2122/97 -------------------------------------------------- Rv3860|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5436|M.marinum_M -------------------------------------------------- MAV_0163|M.avium_104 -------------------------------------------------- MAB_0630|M.abscessus_ATCC_1997 ADYFPQPTLKPPPPLPKAPKLSRRQRNHQRPMNPIWEPDPLSAYGMPQQQ TH_0884|M.thermoresistible__bu -------------------------------------------------- MLBr_00048|M.leprae_Br4923 APLYPPPIIPTCTTTPNGEVASPMPDWSEQLPPNPPAASKSPLPPMPIGS MUL_0202|M.ulcerans_Agy99 -------------------------------------------------- Mvan_0069|M.vanbaalenii_PYR-1 ----------------------------------------------MVND Mflv_0776|M.gilvum_PYR-GCK -----------------------------------------------MTD MSMEG_0053|M.smegmatis_MC2_155 -----------------------------------------------MAD Mb3890|M.bovis_AF2122/97 -----------------------------------------------MYE Rv3860|M.tuberculosis_H37Rv -----------------------------------------------MYE MMAR_5436|M.marinum_M -----------------------------------------------MNE MAV_0163|M.avium_104 -----------------------------------------------MNE MAB_0630|M.abscessus_ATCC_1997 NQAPPAPPQGYGAPVQQPPQNYQPPPQNYYAPPQNYYGPPTDQPATPVAP TH_0884|M.thermoresistible__bu -------------------------------------------------- MLBr_00048|M.leprae_Br4923 SVQPPPASSESPRAPMPVSAPPRSPAASLMPISEPPQWPPAEAPEHQFAK MUL_0202|M.ulcerans_Agy99 -------------------------------------------------- Mvan_0069|M.vanbaalenii_PYR-1 RD-----------------DPAT--------------------------- Mflv_0776|M.gilvum_PYR-GCK RE-----------------EPQ---------------------------- MSMEG_0053|M.smegmatis_MC2_155 PDDTLRRELGWTGPEEDDFEPDTGPTRPTLRPEPPSIPGRPPVSPTPPNP Mb3890|M.bovis_AF2122/97 RD------------------------------------------------ Rv3860|M.tuberculosis_H37Rv RD------------------------------------------------ MMAR_5436|M.marinum_M RE------------------------------------------------ MAV_0163|M.avium_104 RD------------------------------------------------ MAB_0630|M.abscessus_ATCC_1997 AEPAAPAVPPPAPATQLPAWPASAVVPEQPAPEAPAPARPAEQSPAPEGL TH_0884|M.thermoresistible__bu -------------------------------------------------- MLBr_00048|M.leprae_Br4923 AEPPSVPIPINEPSPAKPATPMPMTPIDGSQRTPVTSPEPSLAEFEAQPP MUL_0202|M.ulcerans_Agy99 -------------------------------------------------- Mvan_0069|M.vanbaalenii_PYR-1 ------DQAAVTPEPPRPREMFR-------------------------QP Mflv_0776|M.gilvum_PYR-GCK -----------RHDQERPGGMFR-------------------------QP MSMEG_0053|M.smegmatis_MC2_155 VNPDAEDRVPADPDAERARTTFR-------------------------EP Mb3890|M.bovis_AF2122/97 ------EFLRDRIRPHQPGT------------------------------ Rv3860|M.tuberculosis_H37Rv ------EFLRDRIRPHQPGT------------------------------ MMAR_5436|M.marinum_M ------EFLRDRVRPDQPSVPDASRSHQRSGMHRTATDAS-GPPVAPTHQ MAV_0163|M.avium_104 ------EFLRDRLQPERPSAR----------------------------- MAB_0630|M.abscessus_ATCC_1997 DEAAQEQTPVEVPPPAPPAPVAPDPAPQVRADDASAMIPEGLTPWGGRAP TH_0884|M.thermoresistible__bu -------------------------------------------------- MLBr_00048|M.leprae_Br4923 ATPKPSLLPRPMSSPPEAPRPSAN--------------------QHSRHA MUL_0202|M.ulcerans_Agy99 -------------------------------------------------- Mvan_0069|M.vanbaalenii_PYR-1 TRPLPPQPRR------PDGWEQQQPP------PGW-APQ--APPSAPPYP Mflv_0776|M.gilvum_PYR-GCK TQ--PPQDWT------PPTRPVPAPP------PGY-PPR--PPWPDRPYP MSMEG_0053|M.smegmatis_MC2_155 TQPSPPQQPSQPPPPPPPSALHPRPDPWEQRVPGWNAPQYGPPPGNQPWP Mb3890|M.bovis_AF2122/97 PRGYSPRPPSGDRCPAPPPGRHAAAA------TPPGPPRLPSA-PLRPLP Rv3860|M.tuberculosis_H37Rv PRGYSPRPPSGDRCPAPPPGRHAAAA------TPPGPPRLPSA-PLRPLP MMAR_5436|M.marinum_M PRPAPPRPPTPQPSPVPPRGANPHPP------PPPAPPSVPAP-PPPPVA MAV_0163|M.avium_104 PAPAPPPPPVASR-PAPPRPPTPAPT------PPTRPPAPPTFRPHPPAA MAB_0630|M.abscessus_ATCC_1997 QMPSAPTSPAPSWAPPPAGPPLAPAPPAAFSRADWSAPAAPPRAPYVPGQ TH_0884|M.thermoresistible__bu -------------------------------------------------- MLBr_00048|M.leprae_Br4923 RRGHHHRDETQQANPASATEPMIAPR------ARTAELRQAPHAAAEPAP MUL_0202|M.ulcerans_Agy99 -----------MTDQPPPGGSYPPPP------------------------ Mvan_0069|M.vanbaalenii_PYR-1 PRP---------QADAPWTAPQP-TSYAEWIRPADLVPHRKVVPGSGWRL Mflv_0776|M.gilvum_PYR-GCK ------------QADHP-VPPQP-STYTERIRPADLVPSRKPVPGHGWRL MSMEG_0053|M.smegmatis_MC2_155 QAGGFGG----GPGQPPHVPPGPPQSYADRIRASDLVPPKRQPPSGGWRL Mb3890|M.bovis_AF2122/97 DP---------AWPRQ--PEAPPPSTWAD--PALAPIRSRTRPGERGWRR Rv3860|M.tuberculosis_H37Rv DP---------AWPRQ--PEAPPPSTWAD--PALAPIRSRTRPGERGWRR MMAR_5436|M.marinum_M HPPNGHNSPPQAAPHEPMPEVPPPSLWAE--PTPARTPGEPPSTDHGWRH MAV_0163|M.avium_104 AP----------------APAAPPTPRPQ--PSGAPQLP-----DRGWRR MAB_0630|M.abscessus_ATCC_1997 TPFTAAR-PEAPVYRPVPQPQQPSRPQGPSHDQLGLIRSVKPLPKSGWRK TH_0884|M.thermoresistible__bu ----------------------------VDLSTTALLGQRRPAPSRGWRR MLBr_00048|M.leprae_Br4923 TQHLTRPDGLVSHRTALHDSTATSAIGVQTGRSTGAKKPSKVVAKRGWRH MUL_0202|M.ulcerans_Agy99 --------------------PPPGSSGGSEPPAGGYQAPPPPSAPSGG-- * Mvan_0069|M.vanbaalenii_PYR-1 ALYKASFGLINLGPSPEDKRVAELEATIRTPLRGRFKIGVMG-KGGVGKT Mflv_0776|M.gilvum_PYR-GCK ALLKATFGLVNVGPSPDERRAAALETAIRAPLRGHFKVGVMG-KGGVGKT MSMEG_0053|M.smegmatis_MC2_155 LVYRATFGLVNPGPSAEELRQAELEAKIRGVLRGHYKIGVMG-KGGVGKT Mb3890|M.bovis_AF2122/97 MVRLVTFGLVGLGRSGMQRQEAQFEATIRTVLHGNHKVAVLG-KGGVGKT Rv3860|M.tuberculosis_H37Rv MVRLVTFGLVGLGRSGMQRQEAQFEATIRTVLHGNHKVAVLG-KGGVGKT MMAR_5436|M.marinum_M IIRVASFGLINPRPSAAQRDAAEFEAAIRAPLRGTHKVGVLG-KGGVGKT MAV_0163|M.avium_104 ALRLATFGLIDLGPSPAQRREAQFEQAIQARLYGNYKVGVLG-KGGVGKT MAB_0630|M.abscessus_ATCC_1997 AVHRLSGGAINPGESSEESHRSELIDRINLPVRGDYRIAVLSLKGGVGKT TH_0884|M.thermoresistible__bu WLYRATFRTVNLGESPKVARHNELLNRVRHPLQDCYRIAVLSLKGGVGKT MLBr_00048|M.leprae_Br4923 WVHTVTR--INLGLSPDERYELDLRTRVRRPPRGSYQIGILGLKGGAGKT MUL_0202|M.ulcerans_Agy99 -------GYPPPPPPPPPSTSGYPPPPPPPPLEGGYPPPPPPSAGGYAPP . . . ** . . Mvan_0069|M.vanbaalenii_PYR-1 TVSASIGSVLAEIRQDDRVVAVDADTAFGKLGSRVDPRAQGSFWELAADR Mflv_0776|M.gilvum_PYR-GCK TVSACIGSLFAELRHEDRVVAVDADTAFGKLGSRVDPRARRSFWELTADQ MSMEG_0053|M.smegmatis_MC2_155 TVSATIGSIFAHLRQDDRVVAIDADTSFGKLGSRVDPRAHGSYWELTSDK Mb3890|M.bovis_AF2122/97 SVAACVGSILAELRQQDRIVGIDADTAFGRLSSRIDPRAAGSFWELTTDT Rv3860|M.tuberculosis_H37Rv SVAACVGSILAELRQQDRIVGIDADTAFGRLSSRIDPRAAGSFWELTTDT MMAR_5436|M.marinum_M SVAASIGSLLAELRQQDRIVAVDADTAFGRLSSRIDPTARGSFWDLTADR MAV_0163|M.avium_104 SVAASVGSLFAELRRQDHVVAIDADTAFGRLGSRIDPASTGSFWELTADQ MAB_0630|M.abscessus_ATCC_1997 TTTFSLGATFASLR-GDRVIAVDANPDFGTLAQRGPDETRSTARDLLRDP TH_0884|M.thermoresistible__bu TITATLGSTFGSAR-GDRVVAVDANPDRGTLSQKVPLQTRATVRDLLRDA MLBr_00048|M.leprae_Br4923 TVTVTLGSMFARVR-NDRILVVDADTSCGNLADRAGRFSEANIADLLADK MUL_0202|M.ulcerans_Agy99 PPGPAIRALPAESYTPWITRVLAALIDFAPYVVVTG---IGWLIMMVTTT . : : . : * . : Mvan_0069|M.vanbaalenii_PYR-1 H-LEAFADIRNHLGCNAAGLFVLAGEATPARRRVLDPAIYREATTRLDRH Mflv_0776|M.gilvum_PYR-GCK Y-LETFADIRNHLGSNAAGLFVLAGEASPARRRVLDAAIYREAMARLDRH MSMEG_0053|M.smegmatis_MC2_155 N-LETFADVRSRVGNNSAGLFVLAGESTPARRRVLDAAIYREAVTRLDKH Mb3890|M.bovis_AF2122/97 N-LRSFTDITARLGRNSAGLYVLAGQPASGPRRALDPAIYREAALRLDHH Rv3860|M.tuberculosis_H37Rv N-LRSFTDITARLGRNSAGLYVLAGQPASGPRRVLDPAIYREAALRLDHH MMAR_5436|M.marinum_M N-LASFADVVARLGRNAAGLHVLPGEAAVGGRRLLDPAIYREAALRLDRH MAV_0163|M.avium_104 N-LRSFDDVVARLGRNAAGLHVLGGEPASGPRRVLDPAIYREATRRLDRH MAB_0630|M.abscessus_ATCC_1997 D-IHRYSDVRRHTSQSASRLEVLASERDPAASELFSEADYLAVMRILQRF TH_0884|M.thermoresistible__bu DRIQTYSDMRAYTSQSPSRLEVLASESDPAVSEAFSSDDYTRTLRVLERF MLBr_00048|M.leprae_Br4923 D-VKSYNDIRTHTSVNAVNLEVLPAAEYSTAQHALSGEDWNFAAATVSKY MUL_0202|M.ulcerans_Agy99 P------SCVTDISQYDIGQYCVS-----------QPSMIGQLAQWLLSL . . : . : Mvan_0069|M.vanbaalenii_PYR-1 FTISVIDCSSTMDSPVTQEVLRDLDALVVVSSPWVDGAAAAGQTLDWLAA Mflv_0776|M.gilvum_PYR-GCK FTITVVDCSSTMDSPVTEEVLRDLDALVVVSSPWVDGAAAAGQTLDWLAA MSMEG_0053|M.smegmatis_MC2_155 FSISVVDCSSTMDSPVTQEVLRDLDALIVVSSPWVDGAATAGQTLDWLSA Mb3890|M.bovis_AF2122/97 FAISVIDCGSSMEAAVTQEVLRDVDALIVVSSPWADGASAAANTIEWLSD Rv3860|M.tuberculosis_H37Rv FAISVIDCGSSMEAAVTQEVLRDVDALIVVSSPWADGASAAANTIEWLSD MMAR_5436|M.marinum_M FTISIIDCGSTMDAPLTQEVLRDLDALIVVSSPWADGASAAAKTMEWLAD MAV_0163|M.avium_104 FTISVIDCGSTMDAPLTQEVLRDLDALIVVSSPWADGASAAARTLEWLAD MAB_0630|M.abscessus_ATCC_1997 YNIILTDCGTGLMHSAMAGVLGEANAIVLVTSPAIDGARSALATLDWLDH TH_0884|M.thermoresistible__bu YSLVLTDCGTGLIHSAMSAVLANADVLIVISSGSVDGARSAAATLDWLDA MLBr_00048|M.leprae_Br4923 YNVMLADCGVGLFDPVTRGVLSTASGVVIVTSTSVDAARQAAIALDWLRH MUL_0202|M.ulcerans_Agy99 VGLAYLVWDYGYRQGTTGSSIGKSIMKFKVVSETTGEPLGFGMSVVRQLA : . : . : * . . :: Mvan_0069|M.vanbaalenii_PYR-1 RGLTDLLQRTVVVLNDSDGHADKRTRGILAQQFSGHGQ--LVIEVPFDGH Mflv_0776|M.gilvum_PYR-GCK RGMTTLLQHTVVVLNDSDGHADKRTRKVLAQQFSGHGQ--LVVEVPFDGH MSMEG_0053|M.smegmatis_MC2_155 NGMTRLLQRTVVVLNDSDGHADKRTRSILLNQFAGQGQ--AVVEIPFDGH Mb3890|M.bovis_AF2122/97 YGLTGLLRRSIVVLNDSDGHADKRTKSLLAQEFIDHGQ--PVVEVPFDPH Rv3860|M.tuberculosis_H37Rv YGLTGLLRRSIVVLNDSDGHADKRTKSLLAQEFIDHGQ--PVVEVPFDPH MMAR_5436|M.marinum_M RKLSGLLRRSVVVLNDSDGHSDKRTRSVLAREFVDHGQ--QVVEVPFDPH MAV_0163|M.avium_104 HGLTTLLAHSLVVLNDSDGHADKRTRALLAREFIDHGR--PVIEVPFDPH MAB_0630|M.abscessus_ATCC_1997 HGYSHLVRQSVVAISSSRPGASSIDLEQLSRHFLTRAR--AVHIIPFDNH TH_0884|M.thermoresistible__bu HGHQDMVRNSIAVINAVRPRSGKVDLQKVVDHFSRRCR--AVKMVPFDPH MLBr_00048|M.leprae_Br4923 NGYQDLLSRACVVINHVMPKEPNIASKDLVQQFEQQIQPGRVVVLPWDKH MUL_0202|M.ulcerans_Agy99 HIVDAVICYIGFLFPLWDAKRQTLADKIMTTVCLPL-------------- :: : . : Mvan_0069|M.vanbaalenii_PYR-1 LRPGGVIDGTGEMSPSARRKFIEVVAALAAFFPASVTRSG---------- Mflv_0776|M.gilvum_PYR-GCK LRPGGVIDGTAQMSRPARRKLVEVCAALAAFYPTQDDRSRERR------- MSMEG_0053|M.smegmatis_MC2_155 LRPGGVVD-IQEMSPKVRRKFLEVAAALADHFPTSDDHTRERS------- Mb3890|M.bovis_AF2122/97 LRPGGVIDMSHEMAPTTRLKILQVAATVTAYFASRPADAHGSPPR----- Rv3860|M.tuberculosis_H37Rv LRPGGVIDMSHEMAPTTRLKILQVAATVTAYFASRPADAHGSPPR----- MMAR_5436|M.marinum_M LRPGGVIDVSHELEPGTRLKFLQIAATITGHFAARSAADDDPRPTENVAS MAV_0163|M.avium_104 LRPGGVIDVNGEMAPATRRKFLEVTATIAGYFARRPDRSADRHPPQH--- MAB_0630|M.abscessus_ATCC_1997 LSEGSEIS-LDLMGKKTRMAFMELAGSVADGFYEGGNTRQTSWG------ TH_0884|M.thermoresistible__bu LEEGAEID-LDQLKPQTRQALLELAAVVADGFPGAQQLQSPPF------- MLBr_00048|M.leprae_Br4923 IAAGTEIR-LDRLDPLYRRRILELAAALSDDFERAGRH------------ MUL_0202|M.ulcerans_Agy99 -------------------------------------------------- Mvan_0069|M.vanbaalenii_PYR-1 -- Mflv_0776|M.gilvum_PYR-GCK -- MSMEG_0053|M.smegmatis_MC2_155 -- Mb3890|M.bovis_AF2122/97 -- Rv3860|M.tuberculosis_H37Rv -- MMAR_5436|M.marinum_M ET MAV_0163|M.avium_104 -- MAB_0630|M.abscessus_ATCC_1997 -- TH_0884|M.thermoresistible__bu -- MLBr_00048|M.leprae_Br4923 -- MUL_0202|M.ulcerans_Agy99 --