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NERDEFLRDRLQPERPSARPAPAPPPPPVASRPAPPRPPTPAPTPPTRPPAPPTFRPHPPAAAPAPAAPP TPRPQPSGAPQLPDRGWRRALRLATFGLIDLGPSPAQRREAQFEQAIQARLYGNYKVGVLGKGGVGKTSV AASVGSLFAELRRQDHVVAIDADTAFGRLGSRIDPASTGSFWELTADQNLRSFDDVVARLGRNAAGLHVL GGEPASGPRRVLDPAIYREATRRLDRHFTISVIDCGSTMDAPLTQEVLRDLDALIVVSSPWADGASAAAR TLEWLADHGLTTLLAHSLVVLNDSDGHADKRTRALLAREFIDHGRPVIEVPFDPHLRPGGVIDVNGEMAP ATRRKFLEVTATIAGYFARRPDRSADRHPPQH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0163 | - | - | 100% (383) | hypothetical protein MAV_0163 |
| M. avium 104 | MAV_0156 | - | 2e-44 | 34.13% (293) | hypothetical protein MAV_0156 |
| M. avium 104 | MAV_4615 | - | 3e-40 | 34.04% (376) | hypothetical protein MAV_4615 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3890 | - | 1e-140 | 65.06% (395) | hypothetical protein Mb3890 |
| M. gilvum PYR-GCK | Mflv_0776 | - | 1e-119 | 59.01% (383) | hypothetical protein Mflv_0776 |
| M. tuberculosis H37Rv | Rv3860 | - | 1e-140 | 65.32% (395) | hypothetical protein Rv3860 |
| M. leprae Br4923 | MLBr_00048 | - | 3e-39 | 30.65% (372) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_0630 | - | 7e-49 | 32.98% (379) | hypothetical protein MAB_0630 |
| M. marinum M | MMAR_5436 | - | 1e-143 | 62.73% (432) | hypothetical protein MMAR_5436 |
| M. smegmatis MC2 155 | MSMEG_0053 | - | 1e-112 | 53.61% (388) | hypothetical protein MSMEG_0053 |
| M. thermoresistible (build 8) | TH_0884 | - | 7e-39 | 34.15% (287) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4514 | - | 1e-09 | 47.44% (78) | membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0069 | - | 1e-120 | 57.73% (388) | hypothetical protein Mvan_0069 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0630|M.abscessus_ATCC_1997 MADTNDNAPDSPPPSGPWREPIADGLGGGDTKGSPFRRSKNSNQEFVPPS
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK ------------------------------------MTDRE---------
Mvan_0069|M.vanbaalenii_PYR-1 -----------------------------------MVNDRD---------
MSMEG_0053|M.smegmatis_MC2_155 ------------------------------------MADPDDTLRRELGW
Mb3890|M.bovis_AF2122/97 ------------------------------------MYERD---------
Rv3860|M.tuberculosis_H37Rv ------------------------------------MYERD---------
MMAR_5436|M.marinum_M ------------------------------------MNERE---------
MAV_0163|M.avium_104 ------------------------------------MNERD---------
MLBr_00048|M.leprae_Br4923 -----------MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPPPIIP
MUL_4514|M.ulcerans_Agy99 ----------MRIGGRWVAHPAVASVRQRALRAKTPVFG-----------
MAB_0630|M.abscessus_ATCC_1997 ADYFPQPTLKPPPPLPKAPKLSRRQRNHQRPMNPIWEPDPLSAYGMPQQQ
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK --------EPQ---------------------------------------
Mvan_0069|M.vanbaalenii_PYR-1 --------DPAT---------------------------------DQAAV
MSMEG_0053|M.smegmatis_MC2_155 TGPEEDDFEPDTGPTRPTLRPEPPSIPGRPPVSPTPPNPVNPDAEDRVPA
Mb3890|M.bovis_AF2122/97 ---------------------------------------------EFLRD
Rv3860|M.tuberculosis_H37Rv ---------------------------------------------EFLRD
MMAR_5436|M.marinum_M ---------------------------------------------EFLRD
MAV_0163|M.avium_104 ---------------------------------------------EFLRD
MLBr_00048|M.leprae_Br4923 TCTTTPNGEVASPMPDWSEQLPPNPPAASKSPLPPMPIGSSVQPPPASSE
MUL_4514|M.ulcerans_Agy99 ---------------------------------------IAMITPLVFAG
MAB_0630|M.abscessus_ATCC_1997 NQAPPAPPQGYGAPVQQPPQNYQPPPQNYYAPPQNYYGPPTDQPATPVAP
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK RHDQERPGGMFR------------------------QPTQ--PPQDWT--
Mvan_0069|M.vanbaalenii_PYR-1 TPEPPRPREMFR------------------------QPTRPLPPQPRR--
MSMEG_0053|M.smegmatis_MC2_155 DPDAERARTTFR------------------------EPTQPSPPQQPSQP
Mb3890|M.bovis_AF2122/97 RIRPHQPGT-----------------------------PRGYSPRPPSGD
Rv3860|M.tuberculosis_H37Rv RIRPHQPGT-----------------------------PRGYSPRPPSGD
MMAR_5436|M.marinum_M RVRPDQPSVPDASRSHQRSGMHRTATDASGPPVAPTHQPRPAPPRPPTPQ
MAV_0163|M.avium_104 RLQPERPSAR----------------------------PAPAPPPPPVAS
MLBr_00048|M.leprae_Br4923 SPRAPMPVSAPPRSPAASLMPISEPPQWPPAEAPEHQFAKAEPPSVPIPI
MUL_4514|M.ulcerans_Agy99 AVGATAPASYG-------------------------KTPAVRAAITPVAA
MAB_0630|M.abscessus_ATCC_1997 AEPAAPAVPPPAPATQLPAWPASAVVPEQPAPEAPAPARPAEQSPAPEGL
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK ----PPTRPVPAPP------------------------------------
Mvan_0069|M.vanbaalenii_PYR-1 ----PDGWEQQQPP------------------------------------
MSMEG_0053|M.smegmatis_MC2_155 PPPPPPSALHPRPDPWEQRV------------------------------
Mb3890|M.bovis_AF2122/97 RCPAPPPGRHAAAA------------------------------------
Rv3860|M.tuberculosis_H37Rv RCPAPPPGRHAAAA------------------------------------
MMAR_5436|M.marinum_M PSPVPPRGANPHPP------------------------------------
MAV_0163|M.avium_104 R-PAPPRPPTPAPT------------------------------------
MLBr_00048|M.leprae_Br4923 NEPSPAKPATPMPMTPIDGSQRTPVTSPEPSLAEFEAQ------------
MUL_4514|M.ulcerans_Agy99 VAPSPAIDLSGPSIVAVE--------------------------------
MAB_0630|M.abscessus_ATCC_1997 DEAAQEQTPVEVPPPAPPAPVAPDPAPQVRADDASAMIPEG--LTPWGGR
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK -------PGY-PPR--PPWPDRPYP-------------------------
Mvan_0069|M.vanbaalenii_PYR-1 -------PGW-APQ--APPSAPPYPPRP----------------------
MSMEG_0053|M.smegmatis_MC2_155 -------PGWNAPQYGPPPGNQPWPQAGGFGG------------------
Mb3890|M.bovis_AF2122/97 -------TPPGPPRLPSA-PLRPLPDP-----------------------
Rv3860|M.tuberculosis_H37Rv -------TPPGPPRLPSA-PLRPLPDP-----------------------
MMAR_5436|M.marinum_M -------PPPAPPSVPAP-PPPPVAHPPNGHNSPPQ--------------
MAV_0163|M.avium_104 -------PPTRPPAPPTFRPHPPAAAP-----------------------
MLBr_00048|M.leprae_Br4923 --PPATPKPSLLPRPMSSPPEAPRPSANQHSRHARRGHHHRDETQQANPA
MUL_4514|M.ulcerans_Agy99 -------RPPTNFHIAAGTTAAPPPAR-----------------------
MAB_0630|M.abscessus_ATCC_1997 APQMPSAPTSPAPSWAPPPAGPPLAPAPPAAFSRADWSAPAAPPRAPYVP
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK -----------------QADHP-VPPQP-STYTERI--------------
Mvan_0069|M.vanbaalenii_PYR-1 -----------------QADAPWTAPQP-TSYAEWI--------------
MSMEG_0053|M.smegmatis_MC2_155 ----------------GPGQPPHVPPGPPQSYADRI--------------
Mb3890|M.bovis_AF2122/97 ----------------AWPRQ--PEAPPPSTWAD----------------
Rv3860|M.tuberculosis_H37Rv ----------------AWPRQ--PEAPPPSTWAD----------------
MMAR_5436|M.marinum_M ----------------AAPHEPMPEVPPPSLWAE----------------
MAV_0163|M.avium_104 -----------------------APAAPPTPRPQ----------------
MLBr_00048|M.leprae_Br4923 SATEPMIAPRARTAELRQAPHAAAEPAPTQHLTRPDGLVSHRTALHDSTA
MUL_4514|M.ulcerans_Agy99 -----------------VVNAPGALGIPIMALTAYR--------------
MAB_0630|M.abscessus_ATCC_1997 GQTPFTAARPEAPVYRPVPQPQQPSRPQGPSHDQLGLIRSVKPLPKSGWR
TH_0884|M.thermoresistible__bu -----------------------------VDLSTTALLGQRRPAPSRGWR
Mflv_0776|M.gilvum_PYR-GCK --------------------------------RPADLVPSRKPVPGHGWR
Mvan_0069|M.vanbaalenii_PYR-1 --------------------------------RPADLVPHRKVVPGSGWR
MSMEG_0053|M.smegmatis_MC2_155 --------------------------------RASDLVPPKRQPPSGGWR
Mb3890|M.bovis_AF2122/97 --------------------------------PALAPIRSRTRPGERGWR
Rv3860|M.tuberculosis_H37Rv --------------------------------PALAPIRSRTRPGERGWR
MMAR_5436|M.marinum_M --------------------------------PTPARTPGEPPSTDHGWR
MAV_0163|M.avium_104 --------------------------------PSGAPQLP-----DRGWR
MLBr_00048|M.leprae_Br4923 -----------------------TSAIGVQTGRSTGAKKPSKVVAKRGWR
MUL_4514|M.ulcerans_Agy99 --------------------------------NAEQKMATAAPACGISWN
.*.
MAB_0630|M.abscessus_ATCC_1997 KAVHRLSGGAINPGESSEESHRSELIDRINLPVRGDYRIAVLSLKGGVGK
TH_0884|M.thermoresistible__bu RWLYRATFRTVNLGESPKVARHNELLNRVRHPLQDCYRIAVLSLKGGVGK
Mflv_0776|M.gilvum_PYR-GCK LALLKATFGLVNVGPSPDERRAAALETAIRAPLRGHFKVGVMG-KGGVGK
Mvan_0069|M.vanbaalenii_PYR-1 LALYKASFGLINLGPSPEDKRVAELEATIRTPLRGRFKIGVMG-KGGVGK
MSMEG_0053|M.smegmatis_MC2_155 LLVYRATFGLVNPGPSAEELRQAELEAKIRGVLRGHYKIGVMG-KGGVGK
Mb3890|M.bovis_AF2122/97 RMVRLVTFGLVGLGRSGMQRQEAQFEATIRTVLHGNHKVAVLG-KGGVGK
Rv3860|M.tuberculosis_H37Rv RMVRLVTFGLVGLGRSGMQRQEAQFEATIRTVLHGNHKVAVLG-KGGVGK
MMAR_5436|M.marinum_M HIIRVASFGLINPRPSAAQRDAAEFEAAIRAPLRGTHKVGVLG-KGGVGK
MAV_0163|M.avium_104 RALRLATFGLIDLGPSPAQRREAQFEQAIQARLYGNYKVGVLG-KGGVGK
MLBr_00048|M.leprae_Br4923 HWVHTVTR--INLGLSPDERYELDLRTRVRRPPRGSYQIGILGLKGGAGK
MUL_4514|M.ulcerans_Agy99 LLAGIGRIESMHANGGAVDERGTAVNPIYGPALDGTLPGNEVIIQSKVGN
: . . . : :. .*:
MAB_0630|M.abscessus_ATCC_1997 TTTTFSLGATFASLR-GDRVIAVDANPDFGTLAQRGPDETRSTARDLLRD
TH_0884|M.thermoresistible__bu TTITATLGSTFGSAR-GDRVVAVDANPDRGTLSQKVPLQTRATVRDLLRD
Mflv_0776|M.gilvum_PYR-GCK TTVSACIGSLFAELRHEDRVVAVDADTAFGKLGSRVDPRARRSFWELTAD
Mvan_0069|M.vanbaalenii_PYR-1 TTVSASIGSVLAEIRQDDRVVAVDADTAFGKLGSRVDPRAQGSFWELAAD
MSMEG_0053|M.smegmatis_MC2_155 TTVSATIGSIFAHLRQDDRVVAIDADTSFGKLGSRVDPRAHGSYWELTSD
Mb3890|M.bovis_AF2122/97 TSVAACVGSILAELRQQDRIVGIDADTAFGRLSSRIDPRAAGSFWELTTD
Rv3860|M.tuberculosis_H37Rv TSVAACVGSILAELRQQDRIVGIDADTAFGRLSSRIDPRAAGSFWELTTD
MMAR_5436|M.marinum_M TSVAASIGSLLAELRQQDRIVAVDADTAFGRLSSRIDPTARGSFWDLTAD
MAV_0163|M.avium_104 TSVAASVGSLFAELRRQDHVVAIDADTAFGRLGSRIDPASTGSFWELTAD
MLBr_00048|M.leprae_Br4923 TTVTVTLGSMFARVR-NDRILVVDADTSCGNLADRAGRFSEANIADLLAD
MUL_4514|M.ulcerans_Agy99 RVTYARAMGPMQFLPGTWARYASDGDSDGVPDPQNIFDSTLAAARYLCSG
. : *.:. .. : * .
MAB_0630|M.abscessus_ATCC_1997 PD-IHRYSDVRRHTSQSASRLEVLA-----SERDPAASELFSEADYLAVM
TH_0884|M.thermoresistible__bu ADRIQTYSDMRAYTSQSPSRLEVLA-----SESDPAVSEAFSSDDYTRTL
Mflv_0776|M.gilvum_PYR-GCK QY-LETFADIRNHLGSNAAGLFVLA-----GEASPARRRVLDAAIYREAM
Mvan_0069|M.vanbaalenii_PYR-1 RH-LEAFADIRNHLGCNAAGLFVLA-----GEATPARRRVLDPAIYREAT
MSMEG_0053|M.smegmatis_MC2_155 KN-LETFADVRSRVGNNSAGLFVLA-----GESTPARRRVLDAAIYREAV
Mb3890|M.bovis_AF2122/97 TN-LRSFTDITARLGRNSAGLYVLA-----GQPASGPRRALDPAIYREAA
Rv3860|M.tuberculosis_H37Rv TN-LRSFTDITARLGRNSAGLYVLA-----GQPASGPRRVLDPAIYREAA
MMAR_5436|M.marinum_M RN-LASFADVVARLGRNAAGLHVLP-----GEAAVGGRRLLDPAIYREAA
MAV_0163|M.avium_104 QN-LRSFDDVVARLGRNAAGLHVLG-----GEPASGPRRVLDPAIYREAT
MLBr_00048|M.leprae_Br4923 KD-VKSYNDIRTHTSVNAVNLEVLP-----AAEYSTAQHALSGEDWNFAA
MUL_4514|M.ulcerans_Agy99 GLNLRDPGQVMAAILRYNNSMPYAQNVLGWAAAYATGVLPVDLPPITGPP
: :: : . ..
MAB_0630|M.abscessus_ATCC_1997 RILQRFYNIILTDCGTGLMHSAM-AGVLGEANAIVLVTSPAIDGARSALA
TH_0884|M.thermoresistible__bu RVLERFYSLVLTDCGTGLIHSAM-SAVLANADVLIVISSGSVDGARSAAA
Mflv_0776|M.gilvum_PYR-GCK ARLDRHFTITVVDCSSTMDSPVT-EEVLRDLDALVVVSSPWVDGAAAAGQ
Mvan_0069|M.vanbaalenii_PYR-1 TRLDRHFTISVIDCSSTMDSPVT-QEVLRDLDALVVVSSPWVDGAAAAGQ
MSMEG_0053|M.smegmatis_MC2_155 TRLDKHFSISVVDCSSTMDSPVT-QEVLRDLDALIVVSSPWVDGAATAGQ
Mb3890|M.bovis_AF2122/97 LRLDHHFAISVIDCGSSMEAAVT-QEVLRDVDALIVVSSPWADGASAAAN
Rv3860|M.tuberculosis_H37Rv LRLDHHFAISVIDCGSSMEAAVT-QEVLRDVDALIVVSSPWADGASAAAN
MMAR_5436|M.marinum_M LRLDRHFTISIIDCGSTMDAPLT-QEVLRDLDALIVVSSPWADGASAAAK
MAV_0163|M.avium_104 RRLDRHFTISVIDCGSTMDAPLT-QEVLRDLDALIVVSSPWADGASAAAR
MLBr_00048|M.leprae_Br4923 ATVSKYYNVMLADCGVGLFDPVT-RGVLSTASGVVIVTSTSVDAARQAAI
MUL_4514|M.ulcerans_Agy99 PPIGDAHLEHPEGLGPNLPLNANGLEPADPLSHMPLIDFAPPQMPAPPPP
: . . . : . : :: : . .
MAB_0630|M.abscessus_ATCC_1997 TLDWLDHHGYSHLVRQSVVAISSSRPGASSIDLEQLSRHFLTRAR--AVH
TH_0884|M.thermoresistible__bu TLDWLDAHGHQDMVRNSIAVINAVRPRSGKVDLQKVVDHFSRRCR--AVK
Mflv_0776|M.gilvum_PYR-GCK TLDWLAARGMTTLLQHTVVVLNDSDGHADKRTRKVLAQQFSGHGQ--LVV
Mvan_0069|M.vanbaalenii_PYR-1 TLDWLAARGLTDLLQRTVVVLNDSDGHADKRTRGILAQQFSGHGQ--LVI
MSMEG_0053|M.smegmatis_MC2_155 TLDWLSANGMTRLLQRTVVVLNDSDGHADKRTRSILLNQFAGQGQ--AVV
Mb3890|M.bovis_AF2122/97 TIEWLSDYGLTGLLRRSIVVLNDSDGHADKRTKSLLAQEFIDHGQ--PVV
Rv3860|M.tuberculosis_H37Rv TIEWLSDYGLTGLLRRSIVVLNDSDGHADKRTKSLLAQEFIDHGQ--PVV
MMAR_5436|M.marinum_M TMEWLADRKLSGLLRRSVVVLNDSDGHSDKRTRSVLAREFVDHGQ--QVV
MAV_0163|M.avium_104 TLEWLADHGLTTLLAHSLVVLNDSDGHADKRTRALLAREFIDHGR--PVI
MLBr_00048|M.leprae_Br4923 ALDWLRHNGYQDLLSRACVVINHVMPKEPNIASKDLVQQFEQQIQPGRVV
MUL_4514|M.ulcerans_Agy99 MFPWMQPTPQPLAPQPGCTLICVTNPPEAVPPPAPMPFGLMPPPP-APAA
: *: . : : : .
MAB_0630|M.abscessus_ATCC_1997 IIPFDNHLSEGSEIS-LDLMGKKTRMAFMELAGSVADGFYEGGNTRQTSW
TH_0884|M.thermoresistible__bu MVPFDPHLEEGAEID-LDQLKPQTRQALLELAAVVADGFPGAQQLQSPPF
Mflv_0776|M.gilvum_PYR-GCK EVPFDGHLRPGGVIDGTAQMSRPARRKLVEVCAALAAFYPTQDDRSRERR
Mvan_0069|M.vanbaalenii_PYR-1 EVPFDGHLRPGGVIDGTGEMSPSARRKFIEVVAALAAFFPASVTRSG---
MSMEG_0053|M.smegmatis_MC2_155 EIPFDGHLRPGGVVD-IQEMSPKVRRKFLEVAAALADHFPTSDDHTRERS
Mb3890|M.bovis_AF2122/97 EVPFDPHLRPGGVIDMSHEMAPTTRLKILQVAATVTAYFASRPADAHGSP
Rv3860|M.tuberculosis_H37Rv EVPFDPHLRPGGVIDMSHEMAPTTRLKILQVAATVTAYFASRPADAHGSP
MMAR_5436|M.marinum_M EVPFDPHLRPGGVIDVSHELEPGTRLKFLQIAATITGHFAARSAADDDPR
MAV_0163|M.avium_104 EVPFDPHLRPGGVIDVNGEMAPATRRKFLEVTATIAGYFARRPDRSADRH
MLBr_00048|M.leprae_Br4923 VLPWDKHIAAGTEIR-LDRLDPLYRRRILELAAALSDDFERAGRH-----
MUL_4514|M.ulcerans_Agy99 PPPPDPLAPLGVPPVGGPPAAPAPAPAGPPVPGGPAPAGPAPAPAGPAPA
* * * : . :
MAB_0630|M.abscessus_ATCC_1997 G----------------------------
TH_0884|M.thermoresistible__bu -----------------------------
Mflv_0776|M.gilvum_PYR-GCK -----------------------------
Mvan_0069|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_0053|M.smegmatis_MC2_155 -----------------------------
Mb3890|M.bovis_AF2122/97 PR---------------------------
Rv3860|M.tuberculosis_H37Rv PR---------------------------
MMAR_5436|M.marinum_M PTENVASET--------------------
MAV_0163|M.avium_104 PPQH-------------------------
MLBr_00048|M.leprae_Br4923 -----------------------------
MUL_4514|M.ulcerans_Agy99 PGAPAPAGPAPTPTPSGPAPGEPVLTPVH