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MNEREEFLRDRVRPDQPSVPDASRSHQRSGMHRTATDASGPPVAPTHQPRPAPPRPPTPQPSPVPPRGAN PHPPPPPAPPSVPAPPPPPVAHPPNGHNSPPQAAPHEPMPEVPPPSLWAEPTPARTPGEPPSTDHGWRHI IRVASFGLINPRPSAAQRDAAEFEAAIRAPLRGTHKVGVLGKGGVGKTSVAASIGSLLAELRQQDRIVAV DADTAFGRLSSRIDPTARGSFWDLTADRNLASFADVVARLGRNAAGLHVLPGEAAVGGRRLLDPAIYREA ALRLDRHFTISIIDCGSTMDAPLTQEVLRDLDALIVVSSPWADGASAAAKTMEWLADRKLSGLLRRSVVV LNDSDGHSDKRTRSVLAREFVDHGQQVVEVPFDPHLRPGGVIDVSHELEPGTRLKFLQIAATITGHFAAR SAADDDPRPTENVASET
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5436 | - | - | 100% (437) | hypothetical protein MMAR_5436 |
| M. marinum M | MMAR_5451 | - | 5e-35 | 29.12% (388) | hypothetical protein MMAR_5451 |
| M. marinum M | MMAR_0876 | - | 4e-33 | 28.68% (387) | hypothetical protein MMAR_0876 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3890 | - | 1e-140 | 60.19% (422) | hypothetical protein Mb3890 |
| M. gilvum PYR-GCK | Mflv_0776 | - | 1e-110 | 54.71% (382) | hypothetical protein Mflv_0776 |
| M. tuberculosis H37Rv | Rv3860 | - | 1e-141 | 60.19% (422) | hypothetical protein Rv3860 |
| M. leprae Br4923 | MLBr_00048 | - | 9e-40 | 27.35% (457) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_0630 | - | 7e-47 | 29.89% (455) | hypothetical protein MAB_0630 |
| M. avium 104 | MAV_0163 | - | 1e-140 | 61.11% (432) | hypothetical protein MAV_0163 |
| M. smegmatis MC2 155 | MSMEG_0053 | - | 1e-114 | 49.34% (456) | hypothetical protein MSMEG_0053 |
| M. thermoresistible (build 8) | TH_0884 | - | 2e-34 | 31.44% (299) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0202 | pra | 2e-10 | 34.69% (98) | proline-rich antigen Pra-like protein |
| M. vanbaalenii PYR-1 | Mvan_0069 | - | 1e-116 | 56.73% (379) | hypothetical protein Mvan_0069 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0776|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0069|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0053|M.smegmatis_MC2_155 --------------------------------------------------
Mb3890|M.bovis_AF2122/97 --------------------------------------------------
Rv3860|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5436|M.marinum_M --------------------------------------------------
MAV_0163|M.avium_104 --------------------------------------------------
MAB_0630|M.abscessus_ATCC_1997 MADTNDNAPDSPPPSGPWREPIADGLGGGDTKGSPFRRSKNSNQEFVPPS
TH_0884|M.thermoresistible__bu --------------------------------------------------
MLBr_00048|M.leprae_Br4923 ---------------------MAADYDKLFRLDDGAYASPDQAAEQLFDD
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0069|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0053|M.smegmatis_MC2_155 --------------------------------------------------
Mb3890|M.bovis_AF2122/97 --------------------------------------------------
Rv3860|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5436|M.marinum_M --------------------------------------------------
MAV_0163|M.avium_104 --------------------------------------------------
MAB_0630|M.abscessus_ATCC_1997 ADYFPQPTLKPPPPLPKAPKLSRRQRNHQRPMNPIWEPDPLSAYGMPQQQ
TH_0884|M.thermoresistible__bu --------------------------------------------------
MLBr_00048|M.leprae_Br4923 APLYPPPIIPTCTTTPNGEVASPMPDWSEQLPPNPPAASKSPLPPMPIGS
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK -----------------------------------------------MTD
Mvan_0069|M.vanbaalenii_PYR-1 ----------------------------------------------MVND
MSMEG_0053|M.smegmatis_MC2_155 -----------------------------------------------MAD
Mb3890|M.bovis_AF2122/97 -----------------------------------------------MYE
Rv3860|M.tuberculosis_H37Rv -----------------------------------------------MYE
MMAR_5436|M.marinum_M -----------------------------------------------MNE
MAV_0163|M.avium_104 -----------------------------------------------MNE
MAB_0630|M.abscessus_ATCC_1997 NQAPPAPPQGYGAPVQQPPQNYQPPPQNYYAPPQNYYGPPTDQPATPVAP
TH_0884|M.thermoresistible__bu --------------------------------------------------
MLBr_00048|M.leprae_Br4923 SVQPPPASSESPRAPMPVSAPPRSPAASLMPISEPPQWPPAEAPEHQFAK
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK RE-----------------EPQ----------------------------
Mvan_0069|M.vanbaalenii_PYR-1 RD-----------------DPAT---------------------------
MSMEG_0053|M.smegmatis_MC2_155 PDDTLRRELGWTGPEEDDFEPDTGPTRPTLRPEPPSIPGRPPVSPTPPNP
Mb3890|M.bovis_AF2122/97 RD------------------------------------------------
Rv3860|M.tuberculosis_H37Rv RD------------------------------------------------
MMAR_5436|M.marinum_M RE------------------------------------------------
MAV_0163|M.avium_104 RD------------------------------------------------
MAB_0630|M.abscessus_ATCC_1997 AEPAAPAVPPPAPATQLPAWPASAVVPEQPAPEAPAPARPAEQSPAPEGL
TH_0884|M.thermoresistible__bu --------------------------------------------------
MLBr_00048|M.leprae_Br4923 AEPPSVPIPINEPSPAKPATPMPMTPIDGSQRTPVTSPEPSLAEFEAQPP
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK -----------RHDQERPGGMFR-------------------------QP
Mvan_0069|M.vanbaalenii_PYR-1 ------DQAAVTPEPPRPREMFR-------------------------QP
MSMEG_0053|M.smegmatis_MC2_155 VNPDAEDRVPADPDAERARTTFR-------------------------EP
Mb3890|M.bovis_AF2122/97 ------EFLRDRIRPHQPGT------------------------------
Rv3860|M.tuberculosis_H37Rv ------EFLRDRIRPHQPGT------------------------------
MMAR_5436|M.marinum_M ------EFLRDRVRPDQPSVPDASRSHQRSGMHRTATDAS-GPPVAPTHQ
MAV_0163|M.avium_104 ------EFLRDRLQPERPSAR-----------------------------
MAB_0630|M.abscessus_ATCC_1997 DEAAQEQTPVEVPPPAPPAPVAPDPAPQVRADDASAMIPEGLTPWGGRAP
TH_0884|M.thermoresistible__bu --------------------------------------------------
MLBr_00048|M.leprae_Br4923 ATPKPSLLPRPMSSPPEAPRPSAN--------------------QHSRHA
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK TQ--PPQDWT------PPTRPVPAPP------PGY-PPR--PPWPDRPYP
Mvan_0069|M.vanbaalenii_PYR-1 TRPLPPQPRR------PDGWEQQQPP------PGW-APQ--APPSAPPYP
MSMEG_0053|M.smegmatis_MC2_155 TQPSPPQQPSQPPPPPPPSALHPRPDPWEQRVPGWNAPQYGPPPGNQPWP
Mb3890|M.bovis_AF2122/97 PRGYSPRPPSGDRCPAPPPGRHAAAA------TPPGPPRLPSA-PLRPLP
Rv3860|M.tuberculosis_H37Rv PRGYSPRPPSGDRCPAPPPGRHAAAA------TPPGPPRLPSA-PLRPLP
MMAR_5436|M.marinum_M PRPAPPRPPTPQPSPVPPRGANPHPP------PPPAPPSVPAP-PPPPVA
MAV_0163|M.avium_104 PAPAPPPPPVASR-PAPPRPPTPAPT------PPTRPPAPPTFRPHPPAA
MAB_0630|M.abscessus_ATCC_1997 QMPSAPTSPAPSWAPPPAGPPLAPAPPAAFSRADWSAPAAPPRAPYVPGQ
TH_0884|M.thermoresistible__bu --------------------------------------------------
MLBr_00048|M.leprae_Br4923 RRGHHHRDETQQANPASATEPMIAPR------ARTAELRQAPHAAAEPAP
MUL_0202|M.ulcerans_Agy99 -----------MTDQPPPGGSYPPPP------------------------
Mflv_0776|M.gilvum_PYR-GCK ------------QADHP-VPPQP-STYTERIRPADLVPSRKPVPGHGWRL
Mvan_0069|M.vanbaalenii_PYR-1 PRP---------QADAPWTAPQP-TSYAEWIRPADLVPHRKVVPGSGWRL
MSMEG_0053|M.smegmatis_MC2_155 QAGGFGG----GPGQPPHVPPGPPQSYADRIRASDLVPPKRQPPSGGWRL
Mb3890|M.bovis_AF2122/97 DP---------AWPRQ--PEAPPPSTWAD--PALAPIRSRTRPGERGWRR
Rv3860|M.tuberculosis_H37Rv DP---------AWPRQ--PEAPPPSTWAD--PALAPIRSRTRPGERGWRR
MMAR_5436|M.marinum_M HPPNGHNSPPQAAPHEPMPEVPPPSLWAE--PTPARTPGEPPSTDHGWRH
MAV_0163|M.avium_104 AP----------------APAAPPTPRPQ--PSGAPQLP-----DRGWRR
MAB_0630|M.abscessus_ATCC_1997 TPFTAAR-PEAPVYRPVPQPQQPSRPQGPSHDQLGLIRSVKPLPKSGWRK
TH_0884|M.thermoresistible__bu ----------------------------VDLSTTALLGQRRPAPSRGWRR
MLBr_00048|M.leprae_Br4923 TQHLTRPDGLVSHRTALHDSTATSAIGVQTGRSTGAKKPSKVVAKRGWRH
MUL_0202|M.ulcerans_Agy99 --------------------PPPGSSGGSEPPAGGYQAPPPPSAPSGG--
*
Mflv_0776|M.gilvum_PYR-GCK ALLKATFGLVNVGPSPDERRAAALETAIRAPLRGHFKVGVMG-KGGVGKT
Mvan_0069|M.vanbaalenii_PYR-1 ALYKASFGLINLGPSPEDKRVAELEATIRTPLRGRFKIGVMG-KGGVGKT
MSMEG_0053|M.smegmatis_MC2_155 LVYRATFGLVNPGPSAEELRQAELEAKIRGVLRGHYKIGVMG-KGGVGKT
Mb3890|M.bovis_AF2122/97 MVRLVTFGLVGLGRSGMQRQEAQFEATIRTVLHGNHKVAVLG-KGGVGKT
Rv3860|M.tuberculosis_H37Rv MVRLVTFGLVGLGRSGMQRQEAQFEATIRTVLHGNHKVAVLG-KGGVGKT
MMAR_5436|M.marinum_M IIRVASFGLINPRPSAAQRDAAEFEAAIRAPLRGTHKVGVLG-KGGVGKT
MAV_0163|M.avium_104 ALRLATFGLIDLGPSPAQRREAQFEQAIQARLYGNYKVGVLG-KGGVGKT
MAB_0630|M.abscessus_ATCC_1997 AVHRLSGGAINPGESSEESHRSELIDRINLPVRGDYRIAVLSLKGGVGKT
TH_0884|M.thermoresistible__bu WLYRATFRTVNLGESPKVARHNELLNRVRHPLQDCYRIAVLSLKGGVGKT
MLBr_00048|M.leprae_Br4923 WVHTVTR--INLGLSPDERYELDLRTRVRRPPRGSYQIGILGLKGGAGKT
MUL_0202|M.ulcerans_Agy99 -------GYPPPPPPPPPSTSGYPPPPPPPPLEGGYPPPPPPSAGGYAPP
. . . ** . .
Mflv_0776|M.gilvum_PYR-GCK TVSACIGSLFAELRHEDRVVAVDADTAFGKLGSRVDPRARRSFWELTADQ
Mvan_0069|M.vanbaalenii_PYR-1 TVSASIGSVLAEIRQDDRVVAVDADTAFGKLGSRVDPRAQGSFWELAADR
MSMEG_0053|M.smegmatis_MC2_155 TVSATIGSIFAHLRQDDRVVAIDADTSFGKLGSRVDPRAHGSYWELTSDK
Mb3890|M.bovis_AF2122/97 SVAACVGSILAELRQQDRIVGIDADTAFGRLSSRIDPRAAGSFWELTTDT
Rv3860|M.tuberculosis_H37Rv SVAACVGSILAELRQQDRIVGIDADTAFGRLSSRIDPRAAGSFWELTTDT
MMAR_5436|M.marinum_M SVAASIGSLLAELRQQDRIVAVDADTAFGRLSSRIDPTARGSFWDLTADR
MAV_0163|M.avium_104 SVAASVGSLFAELRRQDHVVAIDADTAFGRLGSRIDPASTGSFWELTADQ
MAB_0630|M.abscessus_ATCC_1997 TTTFSLGATFASLR-GDRVIAVDANPDFGTLAQRGPDETRSTARDLLRDP
TH_0884|M.thermoresistible__bu TITATLGSTFGSAR-GDRVVAVDANPDRGTLSQKVPLQTRATVRDLLRDA
MLBr_00048|M.leprae_Br4923 TVTVTLGSMFARVR-NDRILVVDADTSCGNLADRAGRFSEANIADLLADK
MUL_0202|M.ulcerans_Agy99 PPGPAIRALPAESYTPWITRVLAALIDFAPYVVVTG---IGWLIMMVTTT
. : : . : * . :
Mflv_0776|M.gilvum_PYR-GCK Y-LETFADIRNHLGSNAAGLFVLAGEASPARRRVLDAAIYREAMARLDRH
Mvan_0069|M.vanbaalenii_PYR-1 H-LEAFADIRNHLGCNAAGLFVLAGEATPARRRVLDPAIYREATTRLDRH
MSMEG_0053|M.smegmatis_MC2_155 N-LETFADVRSRVGNNSAGLFVLAGESTPARRRVLDAAIYREAVTRLDKH
Mb3890|M.bovis_AF2122/97 N-LRSFTDITARLGRNSAGLYVLAGQPASGPRRALDPAIYREAALRLDHH
Rv3860|M.tuberculosis_H37Rv N-LRSFTDITARLGRNSAGLYVLAGQPASGPRRVLDPAIYREAALRLDHH
MMAR_5436|M.marinum_M N-LASFADVVARLGRNAAGLHVLPGEAAVGGRRLLDPAIYREAALRLDRH
MAV_0163|M.avium_104 N-LRSFDDVVARLGRNAAGLHVLGGEPASGPRRVLDPAIYREATRRLDRH
MAB_0630|M.abscessus_ATCC_1997 D-IHRYSDVRRHTSQSASRLEVLASERDPAASELFSEADYLAVMRILQRF
TH_0884|M.thermoresistible__bu DRIQTYSDMRAYTSQSPSRLEVLASESDPAVSEAFSSDDYTRTLRVLERF
MLBr_00048|M.leprae_Br4923 D-VKSYNDIRTHTSVNAVNLEVLPAAEYSTAQHALSGEDWNFAAATVSKY
MUL_0202|M.ulcerans_Agy99 P------SCVTDISQYDIGQYCVS-----------QPSMIGQLAQWLLSL
. . : . :
Mflv_0776|M.gilvum_PYR-GCK FTITVVDCSSTMDSPVTEEVLRDLDALVVVSSPWVDGAAAAGQTLDWLAA
Mvan_0069|M.vanbaalenii_PYR-1 FTISVIDCSSTMDSPVTQEVLRDLDALVVVSSPWVDGAAAAGQTLDWLAA
MSMEG_0053|M.smegmatis_MC2_155 FSISVVDCSSTMDSPVTQEVLRDLDALIVVSSPWVDGAATAGQTLDWLSA
Mb3890|M.bovis_AF2122/97 FAISVIDCGSSMEAAVTQEVLRDVDALIVVSSPWADGASAAANTIEWLSD
Rv3860|M.tuberculosis_H37Rv FAISVIDCGSSMEAAVTQEVLRDVDALIVVSSPWADGASAAANTIEWLSD
MMAR_5436|M.marinum_M FTISIIDCGSTMDAPLTQEVLRDLDALIVVSSPWADGASAAAKTMEWLAD
MAV_0163|M.avium_104 FTISVIDCGSTMDAPLTQEVLRDLDALIVVSSPWADGASAAARTLEWLAD
MAB_0630|M.abscessus_ATCC_1997 YNIILTDCGTGLMHSAMAGVLGEANAIVLVTSPAIDGARSALATLDWLDH
TH_0884|M.thermoresistible__bu YSLVLTDCGTGLIHSAMSAVLANADVLIVISSGSVDGARSAAATLDWLDA
MLBr_00048|M.leprae_Br4923 YNVMLADCGVGLFDPVTRGVLSTASGVVIVTSTSVDAARQAAIALDWLRH
MUL_0202|M.ulcerans_Agy99 VGLAYLVWDYGYRQGTTGSSIGKSIMKFKVVSETTGEPLGFGMSVVRQLA
: . : . : * . . ::
Mflv_0776|M.gilvum_PYR-GCK RGMTTLLQHTVVVLNDSDGHADKRTRKVLAQQFSGHGQ--LVVEVPFDGH
Mvan_0069|M.vanbaalenii_PYR-1 RGLTDLLQRTVVVLNDSDGHADKRTRGILAQQFSGHGQ--LVIEVPFDGH
MSMEG_0053|M.smegmatis_MC2_155 NGMTRLLQRTVVVLNDSDGHADKRTRSILLNQFAGQGQ--AVVEIPFDGH
Mb3890|M.bovis_AF2122/97 YGLTGLLRRSIVVLNDSDGHADKRTKSLLAQEFIDHGQ--PVVEVPFDPH
Rv3860|M.tuberculosis_H37Rv YGLTGLLRRSIVVLNDSDGHADKRTKSLLAQEFIDHGQ--PVVEVPFDPH
MMAR_5436|M.marinum_M RKLSGLLRRSVVVLNDSDGHSDKRTRSVLAREFVDHGQ--QVVEVPFDPH
MAV_0163|M.avium_104 HGLTTLLAHSLVVLNDSDGHADKRTRALLAREFIDHGR--PVIEVPFDPH
MAB_0630|M.abscessus_ATCC_1997 HGYSHLVRQSVVAISSSRPGASSIDLEQLSRHFLTRAR--AVHIIPFDNH
TH_0884|M.thermoresistible__bu HGHQDMVRNSIAVINAVRPRSGKVDLQKVVDHFSRRCR--AVKMVPFDPH
MLBr_00048|M.leprae_Br4923 NGYQDLLSRACVVINHVMPKEPNIASKDLVQQFEQQIQPGRVVVLPWDKH
MUL_0202|M.ulcerans_Agy99 HIVDAVICYIGFLFPLWDAKRQTLADKIMTTVCLPL--------------
:: : . :
Mflv_0776|M.gilvum_PYR-GCK LRPGGVIDGTAQMSRPARRKLVEVCAALAAFYPTQDDRSRERR-------
Mvan_0069|M.vanbaalenii_PYR-1 LRPGGVIDGTGEMSPSARRKFIEVVAALAAFFPASVTRSG----------
MSMEG_0053|M.smegmatis_MC2_155 LRPGGVVD-IQEMSPKVRRKFLEVAAALADHFPTSDDHTRERS-------
Mb3890|M.bovis_AF2122/97 LRPGGVIDMSHEMAPTTRLKILQVAATVTAYFASRPADAHGSPPR-----
Rv3860|M.tuberculosis_H37Rv LRPGGVIDMSHEMAPTTRLKILQVAATVTAYFASRPADAHGSPPR-----
MMAR_5436|M.marinum_M LRPGGVIDVSHELEPGTRLKFLQIAATITGHFAARSAADDDPRPTENVAS
MAV_0163|M.avium_104 LRPGGVIDVNGEMAPATRRKFLEVTATIAGYFARRPDRSADRHPPQH---
MAB_0630|M.abscessus_ATCC_1997 LSEGSEIS-LDLMGKKTRMAFMELAGSVADGFYEGGNTRQTSWG------
TH_0884|M.thermoresistible__bu LEEGAEID-LDQLKPQTRQALLELAAVVADGFPGAQQLQSPPF-------
MLBr_00048|M.leprae_Br4923 IAAGTEIR-LDRLDPLYRRRILELAAALSDDFERAGRH------------
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0776|M.gilvum_PYR-GCK --
Mvan_0069|M.vanbaalenii_PYR-1 --
MSMEG_0053|M.smegmatis_MC2_155 --
Mb3890|M.bovis_AF2122/97 --
Rv3860|M.tuberculosis_H37Rv --
MMAR_5436|M.marinum_M ET
MAV_0163|M.avium_104 --
MAB_0630|M.abscessus_ATCC_1997 --
TH_0884|M.thermoresistible__bu --
MLBr_00048|M.leprae_Br4923 --
MUL_0202|M.ulcerans_Agy99 --