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MADFDAQPGRAPKVDLSASQREADEIDLYAGMSGVAGLVAGARTVEQLLADVAEFAGHAIPDVDGVSIAL LQPGPAGPQIQMCAATDAFVADIDRIQYRELHEGPCITAMVTGRVSVSGSLGSDNRWPHFGGRVARMAVH SALSLPLIVDDDVIGAINAYARARDAFGDHAVELGSRFAVPAAVSVYNARLLAGARERTERLQRALGSRA VIDQAVGIIRSRSGGTAQEAFDRLKHLSQTDNVKLVEVAQHLVDEAVRRARARRDP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5218 | - | - | 100% (266) | response regulator receiver/ANTAR domain-containing protein |
| M. gilvum PYR-GCK | Mflv_1809 | - | 1e-25 | 35.09% (228) | response regulator receiver/ANTAR domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3842 | - | 1e-23 | 34.32% (236) | response regulator receiver/ANTAR domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2534c | - | 1e-21 | 32.08% (212) | hypothetical protein MAB_2534c |
| M. marinum M | MMAR_1808 | - | 4e-15 | 26.61% (233) | hypothetical protein MMAR_1808 |
| M. avium 104 | MAV_5172 | - | 3e-27 | 36.11% (216) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6741 | - | 8e-21 | 30.04% (233) | ANTAR domain-containing protein |
| M. thermoresistible (build 8) | TH_2526 | - | 8e-06 | 24.55% (224) | PUTATIVE putative response regulator receiver and ANTAR domain |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1050 | - | 1e-115 | 78.20% (266) | response regulator receiver/ANTAR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 MTGISRRTLGRLAVGAGVLASAVQACAKPGAGHGRSGAPPAPAGKGVGFV
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 LSHEQFRTDRLVAHAQAAERAGFTHGWASDHIQPWQDNEGHSMFPWLTLA
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 LVGSSTSHVSFGTGVTCPTYRYHPATVAQAFASLAILNPGRVFLGVGTGE
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 RLNEQATTNGYGNYTERHDRLAEAIALIRQLWSGSRISFSGRYFQTNSLK
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 LYDVPATPPPIFVAAGGPKSAKLAGQFGDGWITQSGDVTNPKLLAAFGAG
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 AQAAGRDVATLGKRAEMFAVVGDDAVAARAATLWRFTAGAVDQPDPVDIQ
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 RAAESNPTDKVLGGWTGRHRRGSARRGRAAGPRRGRRSLPALSAGRPDGR
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK ----------------MADFDAQPGRAPKVDLSASQRE-------ADEID
Mvan_1050|M.vanbaalenii_PYR-1 ----------------MADFDAQPGRATQTDLSAAQRQ-------ADEID
MAV_5172|M.avium_104 HRLLPGQCLTEIALNPLRATPVSPLPATNSRRIGQNRDVMDAVDPDSRHQ
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------MGESR----------NHE
MAB_2534c|M.abscessus_ATCC_199 --------------------------------MTDEA---------AAGA
MMAR_1808|M.marinum_M ------------------------MTATPKDSNPDSVPG------GTTAD
TH_2526|M.thermoresistible__bu ------------------------------------------------MG
Mflv_5218|M.gilvum_PYR-GCK LYAGMSGVAGLVAGART-VEQLLADVAEFAGHAIPDVDGVSIALLQPGPA
Mvan_1050|M.vanbaalenii_PYR-1 LHAGLDGVAGLVAGARS-IGDLLGDVAAFAAHAIPGVDGVSIALRRTHHE
MAV_5172|M.avium_104 LAVRMAELVRGMAAPRR-LDQVLAEVTAAAVEVIPGADIAGVLLVRKGG-
MSMEG_6741|M.smegmatis_MC2_155 LAMRMADLARAVASPRS-LADVLTGVTTAAKELIPGVDTAGVLLIGPGN-
MAB_2534c|M.abscessus_ATCC_199 FSAKIADAARRMQQEHSSVEMTLRSITTAALETVPGVEQAGITLVTGRY-
MMAR_1808|M.marinum_M PATVFAALAEIIYQGAQ-PAEMYSAICIAATLIVPGCDHASLLVRTNDR-
TH_2526|M.thermoresistible__bu LNATVEKLIRKARASGADTCAVLTELTRSAVGDWPSIQHAGITVVEDGD-
. : * *. : ..: :
Mflv_5218|M.gilvum_PYR-GCK GPQIQMCAATDAFVADIDRIQYRELHEGPCITAMVTGRVSVSGSLGSDNR
Mvan_1050|M.vanbaalenii_PYR-1 PSEVQICSATADFVTEIDRVQYDELHEGPCVTCMLTGRVSVSGSLGSDER
MAV_5172|M.avium_104 --EFETLADTDSLAARLDVLQH-DFGEGPCAQAALQETIVRSDDLRREPR
MSMEG_6741|M.smegmatis_MC2_155 --TFESLAALDELPHALDELQM-RFDEGPCRQAALADLVVRTEDFRAEQR
MAB_2534c|M.abscessus_ATCC_199 --EIESRAATSETPRKLDDIQQ-ELREGPCVQSAWEHETVYAEDLAQTTP
MMAR_1808|M.marinum_M ---YITVGASDRLAQHVDELER-KAGDGPCIDAIEEETPQIETDLTTPTQ
TH_2526|M.thermoresistible__bu --VVRSIAATDGHVLVVDNIAR-RLSTGPGIDAALDEDSYRIDDLRADSR
. :* : ** . .:
Mflv_5218|M.gilvum_PYR-GCK WPHFGGRVARMA-VHSALSLPL------------IVDDDVIGAINAYARA
Mvan_1050|M.vanbaalenii_PYR-1 WPHFGGRVARMA-VHSALSLPL------------IVDDQVIGAINAYAHA
MAV_5172|M.avium_104 WPCYAPAAVQLG-VLSSLSFKL------------YTADRTAGALNLFSHR
MSMEG_6741|M.smegmatis_MC2_155 WPRYSPASVELG-VLSGLSFKL------------YTADRTAGALNLFGFS
MAB_2534c|M.abscessus_ATCC_199 WPRFAEAAVKLG-VRSMLSFQL------------FTFGENLGALNLYAQS
MMAR_1808|M.marinum_M WPKFAAALLAQTPVRGAMGFRL------------LVDKRKGAALNLFSET
TH_2526|M.thermoresistible__bu WPLFADKVAASTPIRSVIAIPVGNPIRNPIRNPIASAGTVRAALSLYSDL
** :. : . :.: : .*:. :.
Mflv_5218|M.gilvum_PYR-GCK RDAFGDHAVELGSRFAVPAAVSVYNARLLA-GARERTERLQRALGSRAVI
Mvan_1050|M.vanbaalenii_PYR-1 RDAFGDHAVQLGTQFAKPAAVAVYNAYLLA-GARERTERLQRALSSRAVI
MAV_5172|M.avium_104 PDAWDTEAETIGSVFAAHAAAAILAG--------SRAEQLYSAVSTRDRI
MSMEG_6741|M.smegmatis_MC2_155 PMNWDEDAVTTGTVLAAHAASAIVAS--------RQEEQLKTALLSRDRI
MAB_2534c|M.abscessus_ATCC_199 PGAFGADSYDAGLALATHAAIVLVAA--------QRESQWASALASRDVI
MMAR_1808|M.marinum_M PNSFDTESAGRAAVLASFASVAVNAIAHG-----EDAASLRRGLLSNREI
TH_2526|M.thermoresistible__bu PGAFDDEVEAVAATYAEHIGRVLTARRGRRRAPVSGSARAQGSVRGQDAI
:. . . * . : .: . *
Mflv_5218|M.gilvum_PYR-GCK DQAVGIIRSRSGGTAQEAFDRLKHLSQTDNVKLVEVAQHLVDEAVRRARA
Mvan_1050|M.vanbaalenii_PYR-1 DQAIGIIRSRSGATAEEAFDRLKRLSQADNVKLAVVAEQLVDEAVRRARA
MAV_5172|M.avium_104 GQAKGIIMERFGVDDVRAFDLLRRLSQESQVKLVEIAQQIIDTRGQGA--
MSMEG_6741|M.smegmatis_MC2_155 GQAKGIIMERYKVDDVQAFEMMRQLSQHSNTRLVDIAGQIIESR------
MAB_2534c|M.abscessus_ATCC_199 GQAKGMLMERFSINAAEAFTVIRTLSQDFNTKLVEIARAIVEDRPLG---
MMAR_1808|M.marinum_M GKAVGMLMLLNGFTEEEAFDLLRHHSQSLNIKLADVARTVIENRGQLPPE
TH_2526|M.thermoresistible__bu ETSKAQLMKHFGVDPAAALTVLLRLSRECNRSLEDVARLLVGPRPVAEPP
: . : *: : *: : * :* ::
Mflv_5218|M.gilvum_PYR-GCK RRDP--------------------
Mvan_1050|M.vanbaalenii_PYR-1 RKTP--------------------
MAV_5172|M.avium_104 ------------------------
MSMEG_6741|M.smegmatis_MC2_155 ------------------------
MAB_2534c|M.abscessus_ATCC_199 ------------------------
MMAR_1808|M.marinum_M ALETDDTVNPTVSG----------
TH_2526|M.thermoresistible__bu SQATATATPDHAGGRPPVWAEGAA