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TDEAAAGAFSAKIADAARRMQQEHSSVEMTLRSITTAALETVPGVEQAGITLVTGRYEIESRAATSETPR KLDDIQQELREGPCVQSAWEHETVYAEDLAQTTPWPRFAEAAVKLGVRSMLSFQLFTFGENLGALNLYAQ SPGAFGADSYDAGLALATHAAIVLVAAQRESQWASALASRDVIGQAKGMLMERFSINAAEAFTVIRTLSQ DFNTKLVEIARAIVEDRPLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2534c | - | - | 100% (231) | hypothetical protein MAB_2534c |
| M. abscessus ATCC 19977 | MAB_2523c | - | 1e-06 | 38.10% (84) | putative transcription antitermination regulator |
| M. abscessus ATCC 19977 | MAB_2586 | - | 9e-05 | 42.86% (49) | putative transcription antitermination regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1809 | - | 6e-44 | 41.20% (216) | response regulator receiver/ANTAR domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1808 | - | 3e-21 | 31.16% (199) | hypothetical protein MMAR_1808 |
| M. avium 104 | MAV_5172 | - | 2e-42 | 40.27% (221) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5554 | - | 7e-47 | 42.01% (219) | ANTAR domain-containing protein |
| M. thermoresistible (build 8) | TH_2526 | - | 3e-19 | 28.22% (241) | PUTATIVE putative response regulator receiver and ANTAR domain |
| M. ulcerans Agy99 | MUL_3601 | - | 3e-05 | 43.75% (48) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4938 | - | 3e-46 | 41.33% (225) | response regulator receiver/ANTAR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 MTGISRRTLGRLAVGAGVLASAVQACAKPGAGHGRSGAPPAPAGKGVGFV
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5554|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 LSHEQFRTDRLVAHAQAAERAGFTHGWASDHIQPWQDNEGHSMFPWLTLA
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5554|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 LVGSSTSHVSFGTGVTCPTYRYHPATVAQAFASLAILNPGRVFLGVGTGE
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5554|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 RLNEQATTNGYGNYTERHDRLAEAIALIRQLWSGSRISFSGRYFQTNSLK
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5554|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 LYDVPATPPPIFVAAGGPKSAKLAGQFGDGWITQSGDVTNPKLLAAFGAG
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5554|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 AQAAGRDVATLGKRAEMFAVVGDDAVAARAATLWRFTAGAVDQPDPVDIQ
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5554|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5172|M.avium_104 RAAESNPTDKVLGGWTGRHRRGSARRGRAAGPRRGRRSLPALSAGRPDGR
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5554|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK ------------------------------------------MNPMPTHE
Mvan_4938|M.vanbaalenii_PYR-1 ------------------------------------------MTETSSHA
MAV_5172|M.avium_104 HRLLPGQCLTEIALNPLRATPVSPLPATNSRRIGQNRDVMDAVDPDSRHQ
MAB_2534c|M.abscessus_ATCC_199 -----------------------------------------MTDEAAAGA
MSMEG_5554|M.smegmatis_MC2_155 ------------------------------------------MSVSQNEA
MMAR_1808|M.marinum_M ------------------------------MTATPKDSNPDSVPGGTTAD
TH_2526|M.thermoresistible__bu ------------------------------------------------MG
MUL_3601|M.ulcerans_Agy99 -------------------------MSSPCHLPTPALSGQVPTVDGLQPS
Mflv_1809|M.gilvum_PYR-GCK LARRMAELARQVASPRR--VEDVLSDVTAEARTLIPGVDAAGVLLVGTAG
Mvan_4938|M.vanbaalenii_PYR-1 LAQRMAELARTVASPRR--VEDVLSDVTREVMGLIPGVDAAGVLFVGAQG
MAV_5172|M.avium_104 LAVRMAELVRGMAAPRR--LDQVLAEVTAAAVEVIPGADIAGVLLVRKGG
MAB_2534c|M.abscessus_ATCC_199 FSAKIADAARRMQQEHSS-VEMTLRSITTAALETVPGVEQAGITLVTGRY
MSMEG_5554|M.smegmatis_MC2_155 ISQQISNLIRDVHTRRATDVDAVLGELTESAVEYVAGAQYAGITIAGRDG
MMAR_1808|M.marinum_M PATVFAALAEIIYQGAQP--AEMYSAICIAATLIVPGCDHASLLVRTN-D
TH_2526|M.thermoresistible__bu LNATVEKLIRKARASGAD-TCAVLTELTRSAVGDWPSIQHAGITVVEDGD
MUL_3601|M.ulcerans_Agy99 SQRSWCALPRALIGSASTLAQCGAGVQVRLGSWWLPGGSGAMISDVQQTA
. .. . * :
Mflv_1809|M.gilvum_PYR-GCK RFESVAGTSELPHRLDELQMRFKEGPCLDAA----------LDQTVVRTD
Mvan_4938|M.vanbaalenii_PYR-1 RFESVAGTSELPHRLDELQMKYRQGPCLEAA----------LDSLIVRTD
MAV_5172|M.avium_104 EFETLADTDSLAARLDVLQHDFGEGPCAQAA----------LQETIVRSD
MAB_2534c|M.abscessus_ATCC_199 EIESRAATSETPRKLDDIQQELREGPCVQSA----------WEHETVYAE
MSMEG_5554|M.smegmatis_MC2_155 KVRTAAATGEYPEILDEIQQRVENGPCLAAA----------WEQHVIRID
MMAR_1808|M.marinum_M RYITVGASDRLAQHVDELERKAGDGPCIDAI----------EEETPQIET
TH_2526|M.thermoresistible__bu VVRSIAATDGHVLVVDNIARRLSTGPGIDAA----------LDEDSYRID
MUL_3601|M.ulcerans_Agy99 HTGEERPDRGTPSFATPISGAVDNHLSIGSFRFWFIGQRWEWSDEVAGMH
: : .
Mflv_1809|M.gilvum_PYR-GCK DFRSEARWPQYA-PAAAEIG-----VLSGLSFKLYTSEQA----------
Mvan_4938|M.vanbaalenii_PYR-1 DFRTEQRWPLYS-AAAAELG-----VLSGLSFKLYTSART----------
MAV_5172|M.avium_104 DLRREPRWPCYA-PAAVQLG-----VLSSLSFKLYTADRT----------
MAB_2534c|M.abscessus_ATCC_199 DLAQTTPWPRFA-EAAVKLG-----VRSMLSFQLFTFGEN----------
MSMEG_5554|M.smegmatis_MC2_155 DMESEQRWPAYCRQALLETP-----IRSVVAFQLYADNQT----------
MMAR_1808|M.marinum_M DLTTPTQWPKFAAALLAQTP-----VRGAMGFRLLVDKRK----------
TH_2526|M.thermoresistible__bu DLRADSRWPLFADKVAASTP-----IRSVIAIPVGNPIRNPIRNPIASAG
MUL_3601|M.ulcerans_Agy99 GYEPGAVVPTTKLLLSHKHPDDRAHVQDLLDYALRSGESFSSRHR-----
. * . : . : :
Mflv_1809|M.gilvum_PYR-GCK --AGALNLFGLRANAFDDEAETIGAILAAHAAAAIIAGRQ--------SE
Mvan_4938|M.vanbaalenii_PYR-1 --AGALNLFALKPNAFDADAETIGAVFAAHAAAAIMASRE--------NE
MAV_5172|M.avium_104 --AGALNLFSHRPDAWDTEAETIGSVFAAHAAAAILAGSR--------AE
MAB_2534c|M.abscessus_ATCC_199 --LGALNLYAQSPGAFGADSYDAGLALATHAAIVLVAAQR--------ES
MSMEG_5554|M.smegmatis_MC2_155 --MGALNFYSETAGAFDAEAVESGLIIATHAALMWSLMRR--------DE
MMAR_1808|M.marinum_M --GAALNLFSETPNSFDTESAGRAAVLASFASVAVNAIAHG-----EDAA
TH_2526|M.thermoresistible__bu TVRAALSLYSDLPGAFDDEVEAVAATYAEHIGRVLTARRGRRRAPVSGSA
MUL_3601|M.ulcerans_Agy99 -FVDTAGVVHDAIVVADRMVNESGVVQGTSGYYIDLTNTFDETRQEVLDE
: .. . . .
Mflv_1809|M.gilvum_PYR-GCK QLESALSTRDRIGQAKGIIMERYDVDDVAAFDMLRRLSQDSNTKLTEVAA
Mvan_4938|M.vanbaalenii_PYR-1 QLQSALSTRDRIGQAKGIIMERYDVDDVTAFEMLRRLSQDSNTKLVEVAA
MAV_5172|M.avium_104 QLYSAVSTRDRIGQAKGIIMERFGVDDVRAFDLLRRLSQESQVKLVEIAQ
MAB_2534c|M.abscessus_ATCC_199 QWASALASRDVIGQAKGMLMERFSINAAEAFTVIRTLSQDFNTKLVEIAR
MSMEG_5554|M.smegmatis_MC2_155 QFRSALASRDLIGQAKGMLMERYRIDAGQAFEVLKKLSQGANTPLVDVAR
MMAR_1808|M.marinum_M SLRRGLLSNREIGKAVGMLMLLNGFTEEEAFDLLRHHSQSLNIKLADVAR
TH_2526|M.thermoresistible__bu RAQGSVRGQDAIETSKAQLMKHFGVDPAAALTVLLRLSRECNRSLEDVAR
MUL_3601|M.ulcerans_Agy99 ALPDLFENRAAIEQAKGVLMAVYRVSAEEAFRVLQWRSQETNTKLRALAK
. . * : . :* . *: :: *: : * :*
Mflv_1809|M.gilvum_PYR-GCK KVIETRGT-----------------------------
Mvan_4938|M.vanbaalenii_PYR-1 KVIETRGT-----------------------------
MAV_5172|M.avium_104 QIIDTRGQGA---------------------------
MAB_2534c|M.abscessus_ATCC_199 AIVEDRPLG----------------------------
MSMEG_5554|M.smegmatis_MC2_155 EIVTTAERPADVSTQ----------------------
MMAR_1808|M.marinum_M TVIENRGQLPPEALETDDTVNPTVSG-----------
TH_2526|M.thermoresistible__bu LLVGPRPVAEPPSQATATATPDHAGGRPPVWAEGAA-
MUL_3601|M.ulcerans_Agy99 QVVAEVASLPPVSALVQSQFDHLLLTVHERIPAESAS
::