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GESRNHELAMRMADLARAVASPRSLADVLTGVTTAAKELIPGVDTAGVLLIGPGNTFESLAALDELPHAL DELQMRFDEGPCRQAALADLVVRTEDFRAEQRWPRYSPASVELGVLSGLSFKLYTADRTAGALNLFGFSP MNWDEDAVTTGTVLAAHAASAIVASRQEEQLKTALLSRDRIGQAKGIIMERYKVDDVQAFEMMRQLSQHS NTRLVDIAGQIIESR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6741 | - | - | 100% (226) | ANTAR domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5554 | - | 1e-42 | 40.27% (226) | ANTAR domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0672 | - | 3e-15 | 31.31% (198) | hypothetical protein MSMEG_0672 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1809 | - | 2e-80 | 64.60% (226) | response regulator receiver/ANTAR domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2534c | - | 4e-45 | 44.44% (216) | hypothetical protein MAB_2534c |
| M. marinum M | MMAR_1808 | - | 2e-22 | 29.95% (217) | hypothetical protein MMAR_1808 |
| M. avium 104 | MAV_5172 | - | 3e-71 | 61.36% (220) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. thermoresistible (build 8) | TH_2526 | - | 2e-14 | 24.14% (232) | PUTATIVE putative response regulator receiver and ANTAR domain |
| M. ulcerans Agy99 | MUL_3601 | - | 0.0001 | 36.36% (55) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4938 | - | 6e-80 | 65.49% (226) | response regulator receiver/ANTAR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5172|M.avium_104 MTGISRRTLGRLAVGAGVLASAVQACAKPGAGHGRSGAPPAPAGKGVGFV
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5172|M.avium_104 LSHEQFRTDRLVAHAQAAERAGFTHGWASDHIQPWQDNEGHSMFPWLTLA
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5172|M.avium_104 LVGSSTSHVSFGTGVTCPTYRYHPATVAQAFASLAILNPGRVFLGVGTGE
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5172|M.avium_104 RLNEQATTNGYGNYTERHDRLAEAIALIRQLWSGSRISFSGRYFQTNSLK
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5172|M.avium_104 LYDVPATPPPIFVAAGGPKSAKLAGQFGDGWITQSGDVTNPKLLAAFGAG
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5172|M.avium_104 AQAAGRDVATLGKRAEMFAVVGDDAVAARAATLWRFTAGAVDQPDPVDIQ
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4938|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5172|M.avium_104 RAAESNPTDKVLGGWTGRHRRGSARRGRAAGPRRGRRSLPALSAGRPDGR
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
TH_2526|M.thermoresistible__bu --------------------------------------------------
MUL_3601|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1809|M.gilvum_PYR-GCK ------------------------------------------MNPMPTHE
Mvan_4938|M.vanbaalenii_PYR-1 ------------------------------------------MTETSSHA
MSMEG_6741|M.smegmatis_MC2_155 ------------------------------------------MGESRNHE
MAV_5172|M.avium_104 HRLLPGQCLTEIALNPLRATPVSPLPATNSRRIGQNRDVMDAVDPDSRHQ
MAB_2534c|M.abscessus_ATCC_199 -----------------------------------------MTDEAAAGA
MMAR_1808|M.marinum_M ------------------------------MTATPKDSNPDSVPGGTTAD
TH_2526|M.thermoresistible__bu ------------------------------------------------MG
MUL_3601|M.ulcerans_Agy99 ---------------------MSSPCHLPTPALSGQVPTVDGLQPSSQRS
Mflv_1809|M.gilvum_PYR-GCK LARRMAELARQVASPRR-VEDVLSDVTAEARTLIPGVDAAGVLLVGTAGR
Mvan_4938|M.vanbaalenii_PYR-1 LAQRMAELARTVASPRR-VEDVLSDVTREVMGLIPGVDAAGVLFVGAQGR
MSMEG_6741|M.smegmatis_MC2_155 LAMRMADLARAVASPRS-LADVLTGVTTAAKELIPGVDTAGVLLIGPGNT
MAV_5172|M.avium_104 LAVRMAELVRGMAAPRR-LDQVLAEVTAAAVEVIPGADIAGVLLVRKGGE
MAB_2534c|M.abscessus_ATCC_199 FSAKIADAARRMQQEHSSVEMTLRSITTAALETVPGVEQAGITLVTGRYE
MMAR_1808|M.marinum_M PATVFAALAEIIYQGAQ-PAEMYSAICIAATLIVPGCDHA-SLLVRTNDR
TH_2526|M.thermoresistible__bu LNATVEKLIRKARASGADTCAVLTELTRSAVGDWPSIQHAGITVVEDGDV
MUL_3601|M.ulcerans_Agy99 WCALPRALIGSASTLAQCGAGVQVRLGSWWLPGGSGAMISDVQQTAHTGE
: .. :
Mflv_1809|M.gilvum_PYR-GCK FESVAGTSELPHRLD-ELQMRFKEGPCLDAALDQTVVRTDDFR-------
Mvan_4938|M.vanbaalenii_PYR-1 FESVAGTSELPHRLD-ELQMKYRQGPCLEAALDSLIVRTDDFR-------
MSMEG_6741|M.smegmatis_MC2_155 FESLAALDELPHALD-ELQMRFDEGPCRQAALADLVVRTEDFR-------
MAV_5172|M.avium_104 FETLADTDSLAARLD-VLQHDFGEGPCAQAALQETIVRSDDLR-------
MAB_2534c|M.abscessus_ATCC_199 IESRAATSETPRKLD-DIQQELREGPCVQSAWEHETVYAEDLA-------
MMAR_1808|M.marinum_M YITVGASDRLAQHVD-ELERKAGDGPCIDAIEEETPQIETDLT-------
TH_2526|M.thermoresistible__bu VRSIAATDGHVLVVD-NIARRLSTGPGIDAALDEDSYRIDDLR-------
MUL_3601|M.ulcerans_Agy99 ERPDRGTPSFATPISGAVDNHLSIGSFRFWFIGQRWEWSDEVAGMHGYEP
. :. : *. :.
Mflv_1809|M.gilvum_PYR-GCK ----SEARWPQYAPAAAEIG-VLSGLSFKLYTSEQA------------AG
Mvan_4938|M.vanbaalenii_PYR-1 ----TEQRWPLYSAAAAELG-VLSGLSFKLYTSART------------AG
MSMEG_6741|M.smegmatis_MC2_155 ----AEQRWPRYSPASVELG-VLSGLSFKLYTADRT------------AG
MAV_5172|M.avium_104 ----REPRWPCYAPAAVQLG-VLSSLSFKLYTADRT------------AG
MAB_2534c|M.abscessus_ATCC_199 ----QTTPWPRFAEAAVKLG-VRSMLSFQLFTFGEN------------LG
MMAR_1808|M.marinum_M ----TPTQWPKFAAALLAQTPVRGAMGFRLLVDKRK------------GA
TH_2526|M.thermoresistible__bu ----ADSRWPLFADKVAASTPIRSVIAIPVGNPIRNPIRNPIASAGTVRA
MUL_3601|M.ulcerans_Agy99 GAVVPTTKLLLSHKHPDDRAHVQDLLDYALRSGESFSSRHR------FVD
: . : :
Mflv_1809|M.gilvum_PYR-GCK ALNLFGLRANAFDDEAETIGAILAAHAAAAIIAGRQ--------SEQLES
Mvan_4938|M.vanbaalenii_PYR-1 ALNLFALKPNAFDADAETIGAVFAAHAAAAIMASRE--------NEQLQS
MSMEG_6741|M.smegmatis_MC2_155 ALNLFGFSPMNWDEDAVTTGTVLAAHAASAIVASRQ--------EEQLKT
MAV_5172|M.avium_104 ALNLFSHRPDAWDTEAETIGSVFAAHAAAAILAGSR--------AEQLYS
MAB_2534c|M.abscessus_ATCC_199 ALNLYAQSPGAFGADSYDAGLALATHAAIVLVAAQR--------ESQWAS
MMAR_1808|M.marinum_M ALNLFSETPNSFDTESAGRAAVLASFASVAVNAIAHGE-----DAASLRR
TH_2526|M.thermoresistible__bu ALSLYSDLPGAFDDEVEAVAATYAEHIGRVLTARRGRRRAPVSGSARAQG
MUL_3601|M.ulcerans_Agy99 TAGVVHDAIVVADRMVNESGVVQGTSGYYIDLTNTFDETRQEVLDEALPD
: .: . . . :
Mflv_1809|M.gilvum_PYR-GCK ALSTRDRIGQAKGIIMERYDVDDVAAFDMLRRLSQDSNTKLTEVAAKVIE
Mvan_4938|M.vanbaalenii_PYR-1 ALSTRDRIGQAKGIIMERYDVDDVTAFEMLRRLSQDSNTKLVEVAAKVIE
MSMEG_6741|M.smegmatis_MC2_155 ALLSRDRIGQAKGIIMERYKVDDVQAFEMMRQLSQHSNTRLVDIAGQIIE
MAV_5172|M.avium_104 AVSTRDRIGQAKGIIMERFGVDDVRAFDLLRRLSQESQVKLVEIAQQIID
MAB_2534c|M.abscessus_ATCC_199 ALASRDVIGQAKGMLMERFSINAAEAFTVIRTLSQDFNTKLVEIARAIVE
MMAR_1808|M.marinum_M GLLSNREIGKAVGMLMLLNGFTEEEAFDLLRHHSQSLNIKLADVARTVIE
TH_2526|M.thermoresistible__bu SVRGQDAIETSKAQLMKHFGVDPAAALTVLLRLSRECNRSLEDVARLLVG
MUL_3601|M.ulcerans_Agy99 LFENRAAIEQAKGVLMAVYRVSAEEAFRVLQWRSQETNTKLRALAKQVVA
. . * : . :* . *: :: *: : * :* ::
Mflv_1809|M.gilvum_PYR-GCK TRGT-----------------------------
Mvan_4938|M.vanbaalenii_PYR-1 TRGT-----------------------------
MSMEG_6741|M.smegmatis_MC2_155 SR-------------------------------
MAV_5172|M.avium_104 TRGQGA---------------------------
MAB_2534c|M.abscessus_ATCC_199 DRPLG----------------------------
MMAR_1808|M.marinum_M NRGQLPPEALETDDTVNPTVSG-----------
TH_2526|M.thermoresistible__bu PRPVAEPPSQATATATPDHAGGRPPVWAEGAA-
MUL_3601|M.ulcerans_Agy99 EVASLPPVSALVQSQFDHLLLTVHERIPAESAS