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ADFDAQPGRATQTDLSAAQRQADEIDLHAGLDGVAGLVAGARSIGDLLGDVAAFAAHAIPGVDGVSIALR RTHHEPSEVQICSATADFVTEIDRVQYDELHEGPCVTCMLTGRVSVSGSLGSDERWPHFGGRVARMAVHS ALSLPLIVDDQVIGAINAYAHARDAFGDHAVQLGTQFAKPAAVAVYNAYLLAGARERTERLQRALSSRAV IDQAIGIIRSRSGATAEEAFDRLKRLSQADNVKLAVVAEQLVDEAVRRARARKTP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1050 | - | - | 100% (266) | response regulator receiver/ANTAR domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2553 | - | 9e-23 | 32.89% (228) | response regulator receiver/ANTAR domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4938 | - | 1e-22 | 31.82% (220) | response regulator receiver/ANTAR domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5218 | - | 1e-115 | 78.20% (266) | response regulator receiver/ANTAR domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2534c | - | 4e-21 | 30.66% (212) | hypothetical protein MAB_2534c |
| M. marinum M | MMAR_1808 | - | 3e-15 | 29.19% (209) | hypothetical protein MMAR_1808 |
| M. avium 104 | MAV_5172 | - | 9e-28 | 35.65% (216) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6741 | - | 1e-19 | 30.45% (220) | ANTAR domain-containing protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5172|M.avium_104 MTGISRRTLGRLAVGAGVLASAVQACAKPGAGHGRSGAPPAPAGKGVGFV
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5172|M.avium_104 LSHEQFRTDRLVAHAQAAERAGFTHGWASDHIQPWQDNEGHSMFPWLTLA
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5172|M.avium_104 LVGSSTSHVSFGTGVTCPTYRYHPATVAQAFASLAILNPGRVFLGVGTGE
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5172|M.avium_104 RLNEQATTNGYGNYTERHDRLAEAIALIRQLWSGSRISFSGRYFQTNSLK
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5172|M.avium_104 LYDVPATPPPIFVAAGGPKSAKLAGQFGDGWITQSGDVTNPKLLAAFGAG
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5172|M.avium_104 AQAAGRDVATLGKRAEMFAVVGDDAVAARAATLWRFTAGAVDQPDPVDIQ
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5218|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5172|M.avium_104 RAAESNPTDKVLGGWTGRHRRGSARRGRAAGPRRGRRSLPALSAGRPDGR
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2534c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1808|M.marinum_M --------------------------------------------------
Mvan_1050|M.vanbaalenii_PYR-1 ----------------MADFDAQPGRATQTDLSAAQRQ-------ADEID
Mflv_5218|M.gilvum_PYR-GCK ----------------MADFDAQPGRAPKVDLSASQRE-------ADEID
MAV_5172|M.avium_104 HRLLPGQCLTEIALNPLRATPVSPLPATNSRRIGQNRDVMDAVDPDSRHQ
MSMEG_6741|M.smegmatis_MC2_155 --------------------------------MGESR----------NHE
MAB_2534c|M.abscessus_ATCC_199 --------------------------------MTDEA---------AAGA
MMAR_1808|M.marinum_M ------------------------MTATPKDSNPDSVPG------GTTAD
.
Mvan_1050|M.vanbaalenii_PYR-1 LHAGLDGVAGLVAGARS-IGDLLGDVAAFAAHAIPGVDGVSIALRRTHHE
Mflv_5218|M.gilvum_PYR-GCK LYAGMSGVAGLVAGART-VEQLLADVAEFAGHAIPDVDGVSIALLQPGPA
MAV_5172|M.avium_104 LAVRMAELVRGMAAPRR-LDQVLAEVTAAAVEVIPGADIAGVLLVRKGG-
MSMEG_6741|M.smegmatis_MC2_155 LAMRMADLARAVASPRS-LADVLTGVTTAAKELIPGVDTAGVLLIGPGN-
MAB_2534c|M.abscessus_ATCC_199 FSAKIADAARRMQQEHSSVEMTLRSITTAALETVPGVEQAGITLVTGRY-
MMAR_1808|M.marinum_M PATVFAALAEIIYQGAQ-PAEMYSAICIAATLIVPGCDHASLLVRTNDR-
: . : : * :*. : ..: :
Mvan_1050|M.vanbaalenii_PYR-1 PSEVQICSATADFVTEIDRVQYDELHEGPCVTCMLTGRVSVSGSLGSDER
Mflv_5218|M.gilvum_PYR-GCK GPQIQMCAATDAFVADIDRIQYRELHEGPCITAMVTGRVSVSGSLGSDNR
MAV_5172|M.avium_104 --EFETLADTDSLAARLDVLQH-DFGEGPCAQAALQETIVRSDDLRREPR
MSMEG_6741|M.smegmatis_MC2_155 --TFESLAALDELPHALDELQM-RFDEGPCRQAALADLVVRTEDFRAEQR
MAB_2534c|M.abscessus_ATCC_199 --EIESRAATSETPRKLDDIQQ-ELREGPCVQSAWEHETVYAEDLAQTTP
MMAR_1808|M.marinum_M ---YITVGASDRLAQHVDELER-KAGDGPCIDAIEEETPQIETDLTTPTQ
. :* :: :*** . .:
Mvan_1050|M.vanbaalenii_PYR-1 WPHFGGRVARMA-VHSALSLPLIVDDQVIGAINAYAHARDAFGDHAVQLG
Mflv_5218|M.gilvum_PYR-GCK WPHFGGRVARMA-VHSALSLPLIVDDDVIGAINAYARARDAFGDHAVELG
MAV_5172|M.avium_104 WPCYAPAAVQLG-VLSSLSFKLYTADRTAGALNLFSHRPDAWDTEAETIG
MSMEG_6741|M.smegmatis_MC2_155 WPRYSPASVELG-VLSGLSFKLYTADRTAGALNLFGFSPMNWDEDAVTTG
MAB_2534c|M.abscessus_ATCC_199 WPRFAEAAVKLG-VRSMLSFQLFTFGENLGALNLYAQSPGAFGADSYDAG
MMAR_1808|M.marinum_M WPKFAAALLAQTPVRGAMGFRLLVDKRKGAALNLFSETPNSFDTESAGRA
** :. * . :.: * . .*:* :. :. .: .
Mvan_1050|M.vanbaalenii_PYR-1 TQFAKPAAVAVYNAYLLAGARERTERLQRALSSRAVIDQAIGIIRSRSGA
Mflv_5218|M.gilvum_PYR-GCK SRFAVPAAVSVYNARLLAGARERTERLQRALGSRAVIDQAVGIIRSRSGG
MAV_5172|M.avium_104 SVFAAHAAAAILAG-------SRAEQLYSAVSTRDRIGQAKGIIMERFGV
MSMEG_6741|M.smegmatis_MC2_155 TVLAAHAASAIVAS-------RQEEQLKTALLSRDRIGQAKGIIMERYKV
MAB_2534c|M.abscessus_ATCC_199 LALATHAAIVLVAA-------QRESQWASALASRDVIGQAKGMLMERFSI
MMAR_1808|M.marinum_M AVLASFASVAVNAIAHG----EDAASLRRGLLSNREIGKAVGMLMLLNGF
:* *: : .: :. *.:* *::
Mvan_1050|M.vanbaalenii_PYR-1 TAEEAFDRLKRLSQADNVKLAVVAEQLVDEAVRRARARKTP---------
Mflv_5218|M.gilvum_PYR-GCK TAQEAFDRLKHLSQTDNVKLVEVAQHLVDEAVRRARARRDP---------
MAV_5172|M.avium_104 DDVRAFDLLRRLSQESQVKLVEIAQQIIDTRGQGA---------------
MSMEG_6741|M.smegmatis_MC2_155 DDVQAFEMMRQLSQHSNTRLVDIAGQIIESR-------------------
MAB_2534c|M.abscessus_ATCC_199 NAAEAFTVIRTLSQDFNTKLVEIARAIVEDRPLG----------------
MMAR_1808|M.marinum_M TEEEAFDLLRHHSQSLNIKLADVARTVIENRGQLPPEALETDDTVNPTVS
.** :: ** : :*. :* :::
Mvan_1050|M.vanbaalenii_PYR-1 -
Mflv_5218|M.gilvum_PYR-GCK -
MAV_5172|M.avium_104 -
MSMEG_6741|M.smegmatis_MC2_155 -
MAB_2534c|M.abscessus_ATCC_199 -
MMAR_1808|M.marinum_M G