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PRTAHTSVVLLDGSAQLPRETLGNKGYGLNIMRRNGLPVPPAFCITTEICAQWLDDPGTTIDGLSETLTQ MIHCLEEQTSRTFGRGPRPLLVSVRSGAALSMPGMMDTVLNLGMNDTVEQALAQTFSARFAMDTRARFAD MYRRIVLDGDASAAVPDDPFLQLLGAIEAVFASWNSPRAVAYRKHHGRDDLGGTAVVVQAMVFGNMESNS GTGVLFSRNPITGADEPFGEWLSSGQGEDVVSGTFDARPISVLAEEQPHVYDELVAAARTLERLGSDVQD IEYTVEEGKLWLLQTRAAKRSAQAAVRLALKLRDEGLIDDMETLRRVTPAHIETLLMPSLQPETRLAAPL LAKGLPACPGVVSGRAVTDVYDAIDAAEDGQDVILVRRSTSPDDVQGMIAALGIVTGIGGTTSHAAVVSR ELGRPSVVGCGADVTDALAGKLITVDGTEGEVREGILELTAWSEDDSSDLAELTRIALAVSPLRAHTTGD YPPLDAGSDDAVRAALAAGHTDVLSSTPLITMLTAVRLAGTDTRELSR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_1960 | - | - | 100% (539) | pyruvate phosphate dikinase |
M. avium 104 | MAV_1259 | - | 0.0 | 67.50% (520) | pyruvate phosphate dikinase |
M. avium 104 | MAV_5059 | - | e-124 | 50.53% (469) | pyruvate phosphate dikinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1158c | ppdK | 1e-179 | 66.81% (479) | pyruvate phosphate dikinase |
M. gilvum PYR-GCK | Mflv_4990 | - | 5e-23 | 27.59% (453) | phosphoenolpyruvate synthase |
M. tuberculosis H37Rv | Rv1127c | ppdK | 1e-179 | 66.81% (479) | pyruvate phosphate dikinase |
M. leprae Br4923 | MLBr_00955 | ppdK | 1e-175 | 60.46% (526) | pyruvate phosphate dikinase |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_4331 | ppdK | 0.0 | 66.09% (522) | pyruvate, phosphate dikinase PpdK |
M. smegmatis MC2 155 | MSMEG_3934 | - | 6e-25 | 28.66% (464) | phosphoenolpyruvate synthase |
M. thermoresistible (build 8) | TH_2849 | - | 1e-120 | 45.58% (566) | PUTATIVE pyruvate, phosphate dikinase |
M. ulcerans Agy99 | MUL_0141 | ppdK | 0.0 | 65.71% (522) | pyruvate phosphate dikinase |
M. vanbaalenii PYR-1 | Mvan_2632 | - | 4e-15 | 31.73% (312) | pyruvate, water dikinase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_4331|M.marinum_M -----MWKHSERSGSLPKTTRGCT-------------------------- MUL_0141|M.ulcerans_Agy99 ---------------MPKTTRGCT-------------------------- Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00955|M.leprae_Br4923 MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAH MAV_1960|M.avium_104 -------------------------------------------------- TH_2849|M.thermoresistible__bu -------------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_3934|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_2632|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4331|M.marinum_M -TTRFSRAGGIP--FTGPAVVLLDGRAHQP-REVLGNKGHGIDSMRRNNL MUL_0141|M.ulcerans_Agy99 -TTRFSRAGGIP--FTGPAVVLLDGRAHQP-REVLGNKGHGIDSMRRNNL Mb1158c|M.bovis_AF2122/97 -MTRITRANGCPDGTLENAVVALDGGANYP-REILGNKGHGIDMMRRHHL Rv1127c|M.tuberculosis_H37Rv -MTRITRANGCPDGTLENAVVALDGGANYP-REILGNKGHGIDMMRRHHL MLBr_00955|M.leprae_Br4923 DKVDITTSSEHVAAFTEHAIVLLNGNAHQT-RELLGGKGYNINAMRRHQL MAV_1960|M.avium_104 ----MPRT-------AHTSVVLLDGSAQLP-RETLGNKGYGLNIMRRNGL TH_2849|M.thermoresistible__bu ----MTAQ------LTEPAVLRITDLETEPSRELVGGKALSLWRMSRLGL Mflv_4990|M.gilvum_PYR-GCK -----------MESGTRNTHVCDISALSIGDAEEAGGKGANMGELVAAKL MSMEG_3934|M.smegmatis_MC2_155 -----------MDIMS-DRYVRTLDILTIADAEEAGGKGANLGELVAADL Mvan_2632|M.vanbaalenii_PYR-1 ---------------MTGTMIHWLTDAGAADPSRSGGKGAKLALLVRAGL : . *.*. : : * MMAR_4331|M.marinum_M PVPPAFCITSEVGVRYLADPAPTLDAIWDDVVDRIRWLEAETGRTFGSGP MUL_0141|M.ulcerans_Agy99 PVPPAFCITSEVGVRYLADPAPTLDAIWDDVVDRIRWLEAETGRTFGSGP Mb1158c|M.bovis_AF2122/97 PVPPAFCITTEVGVRYLAAPESTIAAIWDDVLDRMSWLETETSCTFGRGP Rv1127c|M.tuberculosis_H37Rv PVPPAFCITTEVGVRYLAAPGSTIAAIWDDVLDRMSWLETETSCTFGRGP MLBr_00955|M.leprae_Br4923 AVPPAFCITTEVGVRYLAAPTPTMEAIWNDVLDQMRWLEAETSRTFGWGP MAV_1960|M.avium_104 PVPPAFCITTEICAQWLDDPGTTIDGLSETLTQMIHCLEEQTSRTFGRGP TH_2849|M.thermoresistible__bu RVPPAVVITTRSCAEYFSRGRTLSDELFEEIVSGIGYLEEKTGRRLGASD Mflv_4990|M.gilvum_PYR-GCK PVPPGFVLLRDCYRDSMRAGG-VDAELASLHREALDDVADTARLGELCER MSMEG_3934|M.smegmatis_MC2_155 PVPHGFVVMRSAYLDSVRMGG-VEAELAALHTEALTHAADTARLSELCRR Mvan_2632|M.vanbaalenii_PYR-1 PVPAGFVVLTEAYRRFVSDHG--LDGLIRQQLGAINTGPDGDPDVVHAVS ** .. : . : : MMAR_4331|M.marinum_M HPLLVSVRSGANQSMPGMMDTILDLGMNDTVEQALASPG----TGDFARD MUL_0141|M.ulcerans_Agy99 HPLLVSVRSGANQSMPGMMDTILDLGMNDTVEQALASPG----TGDFARD Mb1158c|M.bovis_AF2122/97 NPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADFAHD Rv1127c|M.tuberculosis_H37Rv NPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADFAHD MLBr_00955|M.leprae_Br4923 RPLLVSIRSGAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTFARD MAV_1960|M.avium_104 RPLLVSVRSGAALSMPGMMDTVLNLGMNDTVEQALAQTF----SARFAMD TH_2849|M.thermoresistible__bu KPLFVSVRSGAAVSMPGMMDTILNLGINETTEAALAAESG---NPQFAAD Mflv_4990|M.gilvum_PYR-GCK MQGLVRKAGVDDATAADMLAAYHAMGPGAVVAVRSSATG-----EDGADA MSMEG_3934|M.smegmatis_MC2_155 MQSLVNKAGLSPSVRDATLAAYRALGTDVVVAVRSSATG-----EDGRDA Mvan_2632|M.vanbaalenii_PYR-1 ARLRAAFESAPMSEELRDQVAAAHSTLGAAASAVRSSAT----AEDLPEA . . : . : MMAR_4331|M.marinum_M TRRRFTRMYRRIVAG----------------------SDPP-DDPYEQLR MUL_0141|M.ulcerans_Agy99 TRRRFTRMYRRIVAG----------------------SDPP-DDPYEQLR Mb1158c|M.bovis_AF2122/97 TRRRFTSMYRRIVGS----------------------AGPITDDPYAQLR Rv1127c|M.tuberculosis_H37Rv TRRRFTSMYRRIVGS----------------------AGPITDDPYAQLR MLBr_00955|M.leprae_Br4923 TRLRFIRTYRRIVDP----------------------LNPPPANTYDQLR MAV_1960|M.avium_104 TRARFADMYRRIVLDGDA-------------------SAAVPDDPFLQLL TH_2849|M.thermoresistible__bu VRRRFSALYGKLVAGCLEDLEDLPDTAAVLQAISEETGSAVPDDPYEALR Mflv_4990|M.gilvum_PYR-GCK SFAGMNATLTNITGD-------------------------------DGLV MSMEG_3934|M.smegmatis_MC2_155 SFAGMNRTITNVMGE-------------------------------VALL Mvan_2632|M.vanbaalenii_PYR-1 SFAGQQDTFLNIVGA-------------------------------EALC .: * MMAR_4331|M.marinum_M AGIGAVFASWNSPRAIAYRNHYSL-DDQGGTAVVVQAMVFGNRSADSGAG MUL_0141|M.ulcerans_Agy99 AGIGAVFASWNSPRAIAYRNHYSL-DDQGGTAVVVQAMVFGNRSADSGAG Mb1158c|M.bovis_AF2122/97 ASIEAVFASWNSPRAVAYRDHHGL-DDQGGTAVVVQAMVFGNLTANSGAG Rv1127c|M.tuberculosis_H37Rv ASIEAVFASWNSPRAVAYRDHHGL-DDQGGTAVVVQAMVFGNLTANSGAG MLBr_00955|M.leprae_Br4923 AAIESIFSSWNSPRAVAYRTHYGL-DDQSGTAVIVQAMVFGNQGAYSGAG MAV_1960|M.avium_104 GAIEAVFASWNSPRAVAYRKHHGR-DDLGGTAVVVQAMVFGNMESNSGTG TH_2849|M.thermoresistible__bu GAVCAVFDSSQSRRAKAYRAHYGI-PDDIGTAVTIQAMVFGNLDDDSGTG Mflv_4990|M.gilvum_PYR-GCK TAVTRCWMSLFSPRVITYRASRGF-LGTPAMAVVVQKMIDSEK-----SG MSMEG_3934|M.smegmatis_MC2_155 DAVTQCWMSLFSPRVITYRASRGF-TAAPAMAVVVQQMLSADR-----AG Mvan_2632|M.vanbaalenii_PYR-1 EAIKRCWSSLWSARAIAYRRDNDIGHEDISIAVVVQSMVPATV-----AG .: : * * *. :** . . ** :* *: . :* MMAR_4331|M.marinum_M VLSSRNPITGASEPFGEWLPGGQGDDVVSGLLKVEPITALHDRLPKIYL- MUL_0141|M.ulcerans_Agy99 VLSSRNPITGASEPFGEWLPGGQGDDVVSGLLKVEPITALRDRLPKIYL- Mb1158c|M.bovis_AF2122/97 VLSSRNPITGANEPFGEWLPGGQGDDVVSGLVAVAPITALRDQQPAVYD- Rv1127c|M.tuberculosis_H37Rv VLSSRNPITGANEPFGEWLPGGQGDDVVSGLVAVAPITALRDQQPAVYD- MLBr_00955|M.leprae_Br4923 TLFSRNPITRESKLFGEWLPGGQGDDVVSGLVEVQPITSLRDEQPTVYD- MAV_1960|M.avium_104 VLFSRNPITGADEPFGEWLSSGQGEDVVSGTFDARPISVLAEEQPHVYD- TH_2849|M.thermoresistible__bu VVFTRNPLTGSREPYGEYLPRGQGEDVVSGRVTPRPLSWLAENRPELHA- Mflv_4990|M.gilvum_PYR-GCK VAFTADPSTGARDRVVIEAAFGLGEVVVSGSVEPDTYVVSKETMEPIDV- MSMEG_3934|M.smegmatis_MC2_155 VAFTSDPSTGDADHIVIEAAFGQGEVVVSGKVEPDTYVIDKRTLEVRDV- Mvan_2632|M.vanbaalenii_PYR-1 VLFTADPISGRRDRIVIEAAAEPGEAVVGGGMTPDRWVLDAVTRRPIDAP . : :* : . . *: **.* . MMAR_4331|M.marinum_M -----------ELLDAARGLERLAAEVQEVEFTVES-GKLWLLQTR---- MUL_0141|M.ulcerans_Agy99 -----------ELLDAARGLERLAAEVQEVEFTVES-GKLWLLQTR---- Mb1158c|M.bovis_AF2122/97 -----------QLMAAARSLERMAGDVQEIEFTVED-SQLWLLQTR---- Rv1127c|M.tuberculosis_H37Rv -----------QLMAAARSLERMAGDVQEIEFTVED-SQLWLLQTR---- MLBr_00955|M.leprae_Br4923 -----------ELVDTAGRLERLGSDVQEIEFTTED-SKLWLLQTR---- MAV_1960|M.avium_104 -----------ELVAAARTLERLGSDVQDIEYTVEE-GKLWLLQTR---- TH_2849|M.thermoresistible__bu -----------ELVSAAELLDREGRDAQDIEFTVQH-GTLYLLQSR---- Mflv_4990|M.gilvum_PYR-GCK -----------RLGNKTFKIVR-GEDGSDTVVQLDD-ATAASRVLT---- MSMEG_3934|M.smegmatis_MC2_155 -----------RIGFKAIKIVR-GDDGADSMVQLER-SQAEARVLD---- Mvan_2632|M.vanbaalenii_PYR-1 ERALLTSEQLDSLVDLGARATAAFGIPQDLEWAVDDDGRCWLLQSRPITS : : : . MMAR_4331|M.marinum_M ----SAERSAQAAVRLALQLRGAGLIDDAE-------------------- MUL_0141|M.ulcerans_Agy99 ----SAERSAQAAVRLALQLRGAGLIDDGE-------------------- Mb1158c|M.bovis_AF2122/97 ----GAERSAQAAVRLALQLHHEGLIDDTE-------------------- Rv1127c|M.tuberculosis_H37Rv ----GAERSAQAAVRLALQLHHEGLIDDTE-------------------- MLBr_00955|M.leprae_Br4923 ----VAERSAQVAVRLALQLWQEGLIDDAE-------------------- MAV_1960|M.avium_104 ----AAKRSAQAAVRLALKLRDEGLIDDME-------------------- TH_2849|M.thermoresistible__bu ----AAKRTAQAAVRIATAMVEEGSIDPAT-------------------- Mflv_4990|M.gilvum_PYR-GCK ----DEELHSVAELAVATERHNGCPQDTEW-------------------- MSMEG_3934|M.smegmatis_MC2_155 ----DDALRKIATLAVATETHNGCPQDIEW-------------------- Mvan_2632|M.vanbaalenii_PYR-1 LFPIPPATRPGLRVYLPVMLIAQGIAEPMTPSGNAFFRTMVGGWFRYWIS : :. : MMAR_4331|M.marinum_M --------------------TLRRITPTHVETLLLP-TLQ---PEERLAA MUL_0141|M.ulcerans_Agy99 --------------------TLRRITPTHVETLLLP-TLH---PDERLAA Mb1158c|M.bovis_AF2122/97 --------------------TLRRVTPTHIETLLRP-SLQ---PETRLAA Rv1127c|M.tuberculosis_H37Rv --------------------TLRRVTPTHIETLLRP-SLQ---TETRLAA MLBr_00955|M.leprae_Br4923 --------------------ALRRVTPVHVETVLLP-VLQ---PENHLSA MAV_1960|M.avium_104 --------------------TLRRVTPAHIETLLMP-SLQ---PETRLAA TH_2849|M.thermoresistible__bu --------------------ACSRVTAEQVRHLLRP-AID---PDRIGDA Mflv_4990|M.gilvum_PYR-GCK --------------------AIADGAAYLVQARPIT-TLGHTTPPARTEH MSMEG_3934|M.smegmatis_MC2_155 --------------------VIADGAVWLVQARPIT-TLGSAGSTAGDEP Mvan_2632|M.vanbaalenii_PYR-1 GRRPRASDADPDWMPIVADRLFLDVTPVLQRPRLAARVLSNFGMKDPAGS : . . : MMAR_4331|M.marinum_M SLLAKGLPACPG----------------------------VAAGLAYTDV MUL_0141|M.ulcerans_Agy99 SLLAKGLPACPG----------------------------VAAGLAYTDV Mb1158c|M.bovis_AF2122/97 PLLAKGLPACPG----------------------------VVSGTAYTEV Rv1127c|M.tuberculosis_H37Rv PLLAKGLPACPG----------------------------VVSGTAYTEV MLBr_00955|M.leprae_Br4923 TLLAKGTPTCPG----------------------------VISGKAYTEV MAV_1960|M.avium_104 PLLAKGLPACPG----------------------------VVSGRAVTDV TH_2849|M.thermoresistible__bu EPIVTGTSASPG----------------------------YAVGIAVGTA Mflv_4990|M.gilvum_PYR-GCK VVLARGLAAAPG----------------------------IASG-KVRVL MSMEG_3934|M.smegmatis_MC2_155 SVLIRGLPAAPG----------------------------VASG-RVRVL Mvan_2632|M.vanbaalenii_PYR-1 AALRKWLSQNSGRLPRPDRAAPPRGLLVLLPSLLAGTVASIAAPTRARRR : . .* MMAR_4331|M.marinum_M DEALDAADRGEQVILVRDHTRPEDVSGMLAAQGIVTEIGGAASHAAVVSR MUL_0141|M.ulcerans_Agy99 DEALDAADRGEQVILVRDHTRPEDVSGMLAAQGIVTEIGGAASHAAVVSR Mb1158c|M.bovis_AF2122/97 DEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGAASHAAVVSR Rv1127c|M.tuberculosis_H37Rv DEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGAASHAAVVSR MLBr_00955|M.leprae_Br4923 DEALDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEVGGAASHAAVVSR MAV_1960|M.avium_104 YDAIDAAEDGQDVILVRRSTSPDDVQGMIAALGIVTGIGGTTSHAAVVSR TH_2849|M.thermoresistible__bu EEAQAKPGS----ILVREATSPEDVHGMIAAAAVVTEKGGSTSHAAVVSR Mflv_4990|M.gilvum_PYR-GCK QTPDEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDTGGMTCHAAIVAR MSMEG_3934|M.smegmatis_MC2_155 LAPDDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVAR Mvan_2632|M.vanbaalenii_PYR-1 IVAGADAELARLEQQAEMLSAPDEQLRFVERELPAATCDMVLRQLAAAYG . . : *: : .: . : * . MMAR_4331|M.marinum_M ELGRVAVVG---------------------CGDGVATSLAGKRITVDGYT MUL_0141|M.ulcerans_Agy99 ELGRVAVVG---------------------CGDGVAASLAGKRITVDGYT Mb1158c|M.bovis_AF2122/97 ELGRVAVVG---------------------CGPGVAAALAGKEITVDGYE Rv1127c|M.tuberculosis_H37Rv ELGRVAVVG---------------------CGPGVAAALAGKEITVDGYE MLBr_00955|M.leprae_Br4923 ELSRVAVVG---------------------CGQGTAVSLAGKQITVDGDK MAV_1960|M.avium_104 ELGRPSVVG---------------------CGADVTDALAGKLITVDGTE TH_2849|M.thermoresistible__bu ALDTPCVVG---------------------CGEGTSSALVGKLVTVDATG Mflv_4990|M.gilvum_PYR-GCK ELGVPCIVG---------------------TRTGTRDLHDGTTVTVDGAR MSMEG_3934|M.smegmatis_MC2_155 ELGVPCVVG---------------------ARSATVALAVGSMVTVDGTR Mvan_2632|M.vanbaalenii_PYR-1 EWLLRVVIERLVRRWLGSSTGFAPVLRWLPHDPTIAMGAALARLAREHAA :: :: : MMAR_4331|M.marinum_M GEVREG------------------------------ILAPSAWSEDDTPE MUL_0141|M.ulcerans_Agy99 GEVREG------------------------------ILAPSAWSEDDTPE Mb1158c|M.bovis_AF2122/97 GEVRQG------------------------------VLALSAWSESDTPE Rv1127c|M.tuberculosis_H37Rv GEVRQG------------------------------VLALSAWSESDTPE MLBr_00955|M.leprae_Br4923 GEVRQG------------------------------NLTLSAWSENETPE MAV_1960|M.avium_104 GEVREG------------------------------ILELTAWSEDDSSD TH_2849|M.thermoresistible__bu GRIYPG------------------------------EIPGRATTVDDDED Mflv_4990|M.gilvum_PYR-GCK GEVASGVTEPAPQMTVSPRSAPAPVTAEVTGTRVYVNLAMPESAETVAAQ MSMEG_3934|M.smegmatis_MC2_155 GEVTTGRLPETVRTTTTPQEPAPHITGEATGTKVYVNLAMPDSAEAVAAQ Mvan_2632|M.vanbaalenii_PYR-1 AGIEPGPESAGVSEFLATFG--------HRAPDREVDLGLPRLSDDPTYV . : * : : MMAR_4331|M.marinum_M LRDLTTIALK------ISPLRAHASGDYPK----------LDDP------ MUL_0141|M.ulcerans_Agy99 LRDLTTIALK------ISPLRAHASGDYPK----------LDDP------ Mb1158c|M.bovis_AF2122/97 LRELADIAQR------ISS------------------------------- Rv1127c|M.tuberculosis_H37Rv LRELADIAQR------ISS------------------------------- MLBr_00955|M.leprae_Br4923 LRELADIARR------ISPLRVHMTEDHTR----------LDDS------ MAV_1960|M.avium_104 LAELTRIALA------VSPLRAHTTGDYPP----------LDAG------ TH_2849|M.thermoresistible__bu LATLLRWARD------LAPIRVVPTADEVDGPVFDADQALIESGEELPTI Mflv_4990|M.gilvum_PYR-GCK PVDGVGLLRA------EFMLTEALGGRHPRDLIARGEQNMLVEKMVDSVG MSMEG_3934|M.smegmatis_MC2_155 DVDGVGLLRA------EFMLTEALAGRHPRDLITKGEQDTLVDAMAAAVT Mvan_2632|M.vanbaalenii_PYR-1 VELINGYLRSGALDTFETGVHEARAASDGLITGVRRVKGPVRAAVLRNLL MMAR_4331|M.marinum_M -------------SEAGVLTAMAAGYT-----DVVSDAPLITMLNALRVQ MUL_0141|M.ulcerans_Agy99 -------------SEAGVLTAMAAGYT-----DVVSDAPLITMLNALRVQ Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------SDTAVRLAINTGHA-----DVVSATPLIVMMTTLRLQ MAV_1960|M.avium_104 -------------SDDAVRAALAAGHT-----DVLSSTPLITMLTAVRLA TH_2849|M.thermoresistible__bu PNGTHAVSGAYFDTDEGVQAALDAGVS-----VIVSTNPLPVLLAAIAYR Mflv_4990|M.gilvum_PYR-GCK RIAAAFSPRPVVYRATDFRSNEFRGLTGGAEYEPVEHNPMIGFRGCYRYV MSMEG_3934|M.smegmatis_MC2_155 RIGTAFAPRPVIYRAMDFRTNEFRGLAGGEQFEPVEHNPMIGYRGCYRYI Mvan_2632|M.vanbaalenii_PYR-1 ARHLALGGLRERPKFDMVRAMALGRRTLRRCGAALVERGLLDDADDVFFL MMAR_4331|M.marinum_M DGL----------------------------------------------- MUL_0141|M.ulcerans_Agy99 DGL----------------------------------------------- Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00955|M.leprae_Br4923 DSKDSSAKS----------------------------------------- MAV_1960|M.avium_104 GTDTRELSR----------------------------------------- TH_2849|M.thermoresistible__bu KDSDD--------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK KEPELFALELEALARVRERSPNVALMIPFVRTRWELEECLSLVDASPLGR MSMEG_3934|M.smegmatis_MC2_155 KEPDLFALELSALARAREHTPNIHLMIPFVRTRWELEECLALVDASPLRR Mvan_2632|M.vanbaalenii_PYR-1 DGADVRAALAGRACDLRARAAADHRSFRRELRRRRVPRVLTSEGEAVYGF MMAR_4331|M.marinum_M -------------------------------------------------- MUL_0141|M.ulcerans_Agy99 -------------------------------------------------- Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_1960|M.avium_104 -------------------------------------------------- TH_2849|M.thermoresistible__bu -------------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK QRGLHRWVMAEVPSVVHWLPEYIGMGIDGVSIGSNDLTQLLLGVDRDSDV MSMEG_3934|M.smegmatis_MC2_155 HRNLHRWVMAEVPSVVHWLPEYVGMGIDGVSIGSNDLTQLMLGVDRDSET Mvan_2632|M.vanbaalenii_PYR-1 DTATPGAETDVLIGTALSPGVHVGTVRVLDSPVGANLQPGEVIVAASTDP MMAR_4331|M.marinum_M -------------------------------------------------- MUL_0141|M.ulcerans_Agy99 -------------------------------------------------- Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_1960|M.avium_104 -------------------------------------------------- TH_2849|M.thermoresistible__bu -------------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK CAELFDESDPAVLHAIRRIVDTANKFGITS---SLCGQAPSTNPAFAEHL MSMEG_3934|M.smegmatis_MC2_155 CAELFDESDAAVLDAISRIISTANRLGITS---SLCGQAPSTRPEFAEHL Mvan_2632|M.vanbaalenii_PYR-1 GWTPLFLLAGALVMEVGGVMSHGALVAREYGLPAVAGIGNAMTRLRSGQR MMAR_4331|M.marinum_M -------------------------------------------------- MUL_0141|M.ulcerans_Agy99 -------------------------------------------------- Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_1960|M.avium_104 -------------------------------------------------- TH_2849|M.thermoresistible__bu -------------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK VRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLPEDQ--------- MSMEG_3934|M.smegmatis_MC2_155 VRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPRHAPTASPRNPL- Mvan_2632|M.vanbaalenii_PYR-1 VRVDGTAGSVTLLDSVAPDGAAEDPAPTADRAAGSGPRPAPRPRPVSPDS MMAR_4331|M.marinum_M - MUL_0141|M.ulcerans_Agy99 - Mb1158c|M.bovis_AF2122/97 - Rv1127c|M.tuberculosis_H37Rv - MLBr_00955|M.leprae_Br4923 - MAV_1960|M.avium_104 - TH_2849|M.thermoresistible__bu - Mflv_4990|M.gilvum_PYR-GCK - MSMEG_3934|M.smegmatis_MC2_155 - Mvan_2632|M.vanbaalenii_PYR-1 R