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M. avium 104 MAV_1960 (-)

annotation: pyruvate phosphate dikinase
coordinates: 1950103 - 1951722
length: 539

PRTAHTSVVLLDGSAQLPRETLGNKGYGLNIMRRNGLPVPPAFCITTEICAQWLDDPGTTIDGLSETLTQ
MIHCLEEQTSRTFGRGPRPLLVSVRSGAALSMPGMMDTVLNLGMNDTVEQALAQTFSARFAMDTRARFAD
MYRRIVLDGDASAAVPDDPFLQLLGAIEAVFASWNSPRAVAYRKHHGRDDLGGTAVVVQAMVFGNMESNS
GTGVLFSRNPITGADEPFGEWLSSGQGEDVVSGTFDARPISVLAEEQPHVYDELVAAARTLERLGSDVQD
IEYTVEEGKLWLLQTRAAKRSAQAAVRLALKLRDEGLIDDMETLRRVTPAHIETLLMPSLQPETRLAAPL
LAKGLPACPGVVSGRAVTDVYDAIDAAEDGQDVILVRRSTSPDDVQGMIAALGIVTGIGGTTSHAAVVSR
ELGRPSVVGCGADVTDALAGKLITVDGTEGEVREGILELTAWSEDDSSDLAELTRIALAVSPLRAHTTGD
YPPLDAGSDDAVRAALAAGHTDVLSSTPLITMLTAVRLAGTDTRELSR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1960--100% (539)pyruvate phosphate dikinase
M. avium 104MAV_1259-0.067.50% (520) pyruvate phosphate dikinase
M. avium 104MAV_5059-e-12450.53% (469) pyruvate phosphate dikinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1158cppdK1e-17966.81% (479) pyruvate phosphate dikinase
M. gilvum PYR-GCKMflv_4990-5e-2327.59% (453) phosphoenolpyruvate synthase
M. tuberculosis H37RvRv1127cppdK1e-17966.81% (479) pyruvate phosphate dikinase
M. leprae Br4923MLBr_00955ppdK1e-17560.46% (526) pyruvate phosphate dikinase
M. abscessus ATCC 19977-----
M. marinum MMMAR_4331ppdK0.066.09% (522) pyruvate, phosphate dikinase PpdK
M. smegmatis MC2 155MSMEG_3934-6e-2528.66% (464) phosphoenolpyruvate synthase
M. thermoresistible (build 8)TH_2849-1e-12045.58% (566) PUTATIVE pyruvate, phosphate dikinase
M. ulcerans Agy99MUL_0141ppdK0.065.71% (522) pyruvate phosphate dikinase
M. vanbaalenii PYR-1Mvan_2632-4e-1531.73% (312) pyruvate, water dikinase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4331|M.marinum_M               -----MWKHSERSGSLPKTTRGCT--------------------------
MUL_0141|M.ulcerans_Agy99           ---------------MPKTTRGCT--------------------------
Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00955|M.leprae_Br4923          MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAH
MAV_1960|M.avium_104                --------------------------------------------------
TH_2849|M.thermoresistible__bu      --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

MMAR_4331|M.marinum_M               -TTRFSRAGGIP--FTGPAVVLLDGRAHQP-REVLGNKGHGIDSMRRNNL
MUL_0141|M.ulcerans_Agy99           -TTRFSRAGGIP--FTGPAVVLLDGRAHQP-REVLGNKGHGIDSMRRNNL
Mb1158c|M.bovis_AF2122/97           -MTRITRANGCPDGTLENAVVALDGGANYP-REILGNKGHGIDMMRRHHL
Rv1127c|M.tuberculosis_H37Rv        -MTRITRANGCPDGTLENAVVALDGGANYP-REILGNKGHGIDMMRRHHL
MLBr_00955|M.leprae_Br4923          DKVDITTSSEHVAAFTEHAIVLLNGNAHQT-RELLGGKGYNINAMRRHQL
MAV_1960|M.avium_104                ----MPRT-------AHTSVVLLDGSAQLP-RETLGNKGYGLNIMRRNGL
TH_2849|M.thermoresistible__bu      ----MTAQ------LTEPAVLRITDLETEPSRELVGGKALSLWRMSRLGL
Mflv_4990|M.gilvum_PYR-GCK          -----------MESGTRNTHVCDISALSIGDAEEAGGKGANMGELVAAKL
MSMEG_3934|M.smegmatis_MC2_155      -----------MDIMS-DRYVRTLDILTIADAEEAGGKGANLGELVAADL
Mvan_2632|M.vanbaalenii_PYR-1       ---------------MTGTMIHWLTDAGAADPSRSGGKGAKLALLVRAGL
                                                        :           .  *.*.  :  :    *

MMAR_4331|M.marinum_M               PVPPAFCITSEVGVRYLADPAPTLDAIWDDVVDRIRWLEAETGRTFGSGP
MUL_0141|M.ulcerans_Agy99           PVPPAFCITSEVGVRYLADPAPTLDAIWDDVVDRIRWLEAETGRTFGSGP
Mb1158c|M.bovis_AF2122/97           PVPPAFCITTEVGVRYLAAPESTIAAIWDDVLDRMSWLETETSCTFGRGP
Rv1127c|M.tuberculosis_H37Rv        PVPPAFCITTEVGVRYLAAPGSTIAAIWDDVLDRMSWLETETSCTFGRGP
MLBr_00955|M.leprae_Br4923          AVPPAFCITTEVGVRYLAAPTPTMEAIWNDVLDQMRWLEAETSRTFGWGP
MAV_1960|M.avium_104                PVPPAFCITTEICAQWLDDPGTTIDGLSETLTQMIHCLEEQTSRTFGRGP
TH_2849|M.thermoresistible__bu      RVPPAVVITTRSCAEYFSRGRTLSDELFEEIVSGIGYLEEKTGRRLGASD
Mflv_4990|M.gilvum_PYR-GCK          PVPPGFVLLRDCYRDSMRAGG-VDAELASLHREALDDVADTARLGELCER
MSMEG_3934|M.smegmatis_MC2_155      PVPHGFVVMRSAYLDSVRMGG-VEAELAALHTEALTHAADTARLSELCRR
Mvan_2632|M.vanbaalenii_PYR-1       PVPAGFVVLTEAYRRFVSDHG--LDGLIRQQLGAINTGPDGDPDVVHAVS
                                     ** .. :        .         :       :               

MMAR_4331|M.marinum_M               HPLLVSVRSGANQSMPGMMDTILDLGMNDTVEQALASPG----TGDFARD
MUL_0141|M.ulcerans_Agy99           HPLLVSVRSGANQSMPGMMDTILDLGMNDTVEQALASPG----TGDFARD
Mb1158c|M.bovis_AF2122/97           NPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADFAHD
Rv1127c|M.tuberculosis_H37Rv        NPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADFAHD
MLBr_00955|M.leprae_Br4923          RPLLVSIRSGAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTFARD
MAV_1960|M.avium_104                RPLLVSVRSGAALSMPGMMDTVLNLGMNDTVEQALAQTF----SARFAMD
TH_2849|M.thermoresistible__bu      KPLFVSVRSGAAVSMPGMMDTILNLGINETTEAALAAESG---NPQFAAD
Mflv_4990|M.gilvum_PYR-GCK          MQGLVRKAGVDDATAADMLAAYHAMGPGAVVAVRSSATG-----EDGADA
MSMEG_3934|M.smegmatis_MC2_155      MQSLVNKAGLSPSVRDATLAAYRALGTDVVVAVRSSATG-----EDGRDA
Mvan_2632|M.vanbaalenii_PYR-1       ARLRAAFESAPMSEELRDQVAAAHSTLGAAASAVRSSAT----AEDLPEA
                                        .   .           :         .    :              

MMAR_4331|M.marinum_M               TRRRFTRMYRRIVAG----------------------SDPP-DDPYEQLR
MUL_0141|M.ulcerans_Agy99           TRRRFTRMYRRIVAG----------------------SDPP-DDPYEQLR
Mb1158c|M.bovis_AF2122/97           TRRRFTSMYRRIVGS----------------------AGPITDDPYAQLR
Rv1127c|M.tuberculosis_H37Rv        TRRRFTSMYRRIVGS----------------------AGPITDDPYAQLR
MLBr_00955|M.leprae_Br4923          TRLRFIRTYRRIVDP----------------------LNPPPANTYDQLR
MAV_1960|M.avium_104                TRARFADMYRRIVLDGDA-------------------SAAVPDDPFLQLL
TH_2849|M.thermoresistible__bu      VRRRFSALYGKLVAGCLEDLEDLPDTAAVLQAISEETGSAVPDDPYEALR
Mflv_4990|M.gilvum_PYR-GCK          SFAGMNATLTNITGD-------------------------------DGLV
MSMEG_3934|M.smegmatis_MC2_155      SFAGMNRTITNVMGE-------------------------------VALL
Mvan_2632|M.vanbaalenii_PYR-1       SFAGQQDTFLNIVGA-------------------------------EALC
                                              .:                                    * 

MMAR_4331|M.marinum_M               AGIGAVFASWNSPRAIAYRNHYSL-DDQGGTAVVVQAMVFGNRSADSGAG
MUL_0141|M.ulcerans_Agy99           AGIGAVFASWNSPRAIAYRNHYSL-DDQGGTAVVVQAMVFGNRSADSGAG
Mb1158c|M.bovis_AF2122/97           ASIEAVFASWNSPRAVAYRDHHGL-DDQGGTAVVVQAMVFGNLTANSGAG
Rv1127c|M.tuberculosis_H37Rv        ASIEAVFASWNSPRAVAYRDHHGL-DDQGGTAVVVQAMVFGNLTANSGAG
MLBr_00955|M.leprae_Br4923          AAIESIFSSWNSPRAVAYRTHYGL-DDQSGTAVIVQAMVFGNQGAYSGAG
MAV_1960|M.avium_104                GAIEAVFASWNSPRAVAYRKHHGR-DDLGGTAVVVQAMVFGNMESNSGTG
TH_2849|M.thermoresistible__bu      GAVCAVFDSSQSRRAKAYRAHYGI-PDDIGTAVTIQAMVFGNLDDDSGTG
Mflv_4990|M.gilvum_PYR-GCK          TAVTRCWMSLFSPRVITYRASRGF-LGTPAMAVVVQKMIDSEK-----SG
MSMEG_3934|M.smegmatis_MC2_155      DAVTQCWMSLFSPRVITYRASRGF-TAAPAMAVVVQQMLSADR-----AG
Mvan_2632|M.vanbaalenii_PYR-1       EAIKRCWSSLWSARAIAYRRDNDIGHEDISIAVVVQSMVPATV-----AG
                                     .:   : *  * *. :**   .      . ** :* *: .       :*

MMAR_4331|M.marinum_M               VLSSRNPITGASEPFGEWLPGGQGDDVVSGLLKVEPITALHDRLPKIYL-
MUL_0141|M.ulcerans_Agy99           VLSSRNPITGASEPFGEWLPGGQGDDVVSGLLKVEPITALRDRLPKIYL-
Mb1158c|M.bovis_AF2122/97           VLSSRNPITGANEPFGEWLPGGQGDDVVSGLVAVAPITALRDQQPAVYD-
Rv1127c|M.tuberculosis_H37Rv        VLSSRNPITGANEPFGEWLPGGQGDDVVSGLVAVAPITALRDQQPAVYD-
MLBr_00955|M.leprae_Br4923          TLFSRNPITRESKLFGEWLPGGQGDDVVSGLVEVQPITSLRDEQPTVYD-
MAV_1960|M.avium_104                VLFSRNPITGADEPFGEWLSSGQGEDVVSGTFDARPISVLAEEQPHVYD-
TH_2849|M.thermoresistible__bu      VVFTRNPLTGSREPYGEYLPRGQGEDVVSGRVTPRPLSWLAENRPELHA-
Mflv_4990|M.gilvum_PYR-GCK          VAFTADPSTGARDRVVIEAAFGLGEVVVSGSVEPDTYVVSKETMEPIDV-
MSMEG_3934|M.smegmatis_MC2_155      VAFTSDPSTGDADHIVIEAAFGQGEVVVSGKVEPDTYVIDKRTLEVRDV-
Mvan_2632|M.vanbaalenii_PYR-1       VLFTADPISGRRDRIVIEAAAEPGEAVVGGGMTPDRWVLDAVTRRPIDAP
                                    .  : :* :   .      .   *: **.* .                  

MMAR_4331|M.marinum_M               -----------ELLDAARGLERLAAEVQEVEFTVES-GKLWLLQTR----
MUL_0141|M.ulcerans_Agy99           -----------ELLDAARGLERLAAEVQEVEFTVES-GKLWLLQTR----
Mb1158c|M.bovis_AF2122/97           -----------QLMAAARSLERMAGDVQEIEFTVED-SQLWLLQTR----
Rv1127c|M.tuberculosis_H37Rv        -----------QLMAAARSLERMAGDVQEIEFTVED-SQLWLLQTR----
MLBr_00955|M.leprae_Br4923          -----------ELVDTAGRLERLGSDVQEIEFTTED-SKLWLLQTR----
MAV_1960|M.avium_104                -----------ELVAAARTLERLGSDVQDIEYTVEE-GKLWLLQTR----
TH_2849|M.thermoresistible__bu      -----------ELVSAAELLDREGRDAQDIEFTVQH-GTLYLLQSR----
Mflv_4990|M.gilvum_PYR-GCK          -----------RLGNKTFKIVR-GEDGSDTVVQLDD-ATAASRVLT----
MSMEG_3934|M.smegmatis_MC2_155      -----------RIGFKAIKIVR-GDDGADSMVQLER-SQAEARVLD----
Mvan_2632|M.vanbaalenii_PYR-1       ERALLTSEQLDSLVDLGARATAAFGIPQDLEWAVDDDGRCWLLQSRPITS
                                                :               :     :  .            

MMAR_4331|M.marinum_M               ----SAERSAQAAVRLALQLRGAGLIDDAE--------------------
MUL_0141|M.ulcerans_Agy99           ----SAERSAQAAVRLALQLRGAGLIDDGE--------------------
Mb1158c|M.bovis_AF2122/97           ----GAERSAQAAVRLALQLHHEGLIDDTE--------------------
Rv1127c|M.tuberculosis_H37Rv        ----GAERSAQAAVRLALQLHHEGLIDDTE--------------------
MLBr_00955|M.leprae_Br4923          ----VAERSAQVAVRLALQLWQEGLIDDAE--------------------
MAV_1960|M.avium_104                ----AAKRSAQAAVRLALKLRDEGLIDDME--------------------
TH_2849|M.thermoresistible__bu      ----AAKRTAQAAVRIATAMVEEGSIDPAT--------------------
Mflv_4990|M.gilvum_PYR-GCK          ----DEELHSVAELAVATERHNGCPQDTEW--------------------
MSMEG_3934|M.smegmatis_MC2_155      ----DDALRKIATLAVATETHNGCPQDIEW--------------------
Mvan_2632|M.vanbaalenii_PYR-1       LFPIPPATRPGLRVYLPVMLIAQGIAEPMTPSGNAFFRTMVGGWFRYWIS
                                                 : :.         :                       

MMAR_4331|M.marinum_M               --------------------TLRRITPTHVETLLLP-TLQ---PEERLAA
MUL_0141|M.ulcerans_Agy99           --------------------TLRRITPTHVETLLLP-TLH---PDERLAA
Mb1158c|M.bovis_AF2122/97           --------------------TLRRVTPTHIETLLRP-SLQ---PETRLAA
Rv1127c|M.tuberculosis_H37Rv        --------------------TLRRVTPTHIETLLRP-SLQ---TETRLAA
MLBr_00955|M.leprae_Br4923          --------------------ALRRVTPVHVETVLLP-VLQ---PENHLSA
MAV_1960|M.avium_104                --------------------TLRRVTPAHIETLLMP-SLQ---PETRLAA
TH_2849|M.thermoresistible__bu      --------------------ACSRVTAEQVRHLLRP-AID---PDRIGDA
Mflv_4990|M.gilvum_PYR-GCK          --------------------AIADGAAYLVQARPIT-TLGHTTPPARTEH
MSMEG_3934|M.smegmatis_MC2_155      --------------------VIADGAVWLVQARPIT-TLGSAGSTAGDEP
Mvan_2632|M.vanbaalenii_PYR-1       GRRPRASDADPDWMPIVADRLFLDVTPVLQRPRLAARVLSNFGMKDPAGS
                                                             :    .    .  :           

MMAR_4331|M.marinum_M               SLLAKGLPACPG----------------------------VAAGLAYTDV
MUL_0141|M.ulcerans_Agy99           SLLAKGLPACPG----------------------------VAAGLAYTDV
Mb1158c|M.bovis_AF2122/97           PLLAKGLPACPG----------------------------VVSGTAYTEV
Rv1127c|M.tuberculosis_H37Rv        PLLAKGLPACPG----------------------------VVSGTAYTEV
MLBr_00955|M.leprae_Br4923          TLLAKGTPTCPG----------------------------VISGKAYTEV
MAV_1960|M.avium_104                PLLAKGLPACPG----------------------------VVSGRAVTDV
TH_2849|M.thermoresistible__bu      EPIVTGTSASPG----------------------------YAVGIAVGTA
Mflv_4990|M.gilvum_PYR-GCK          VVLARGLAAAPG----------------------------IASG-KVRVL
MSMEG_3934|M.smegmatis_MC2_155      SVLIRGLPAAPG----------------------------VASG-RVRVL
Mvan_2632|M.vanbaalenii_PYR-1       AALRKWLSQNSGRLPRPDRAAPPRGLLVLLPSLLAGTVASIAAPTRARRR
                                      :    .  .*                                      

MMAR_4331|M.marinum_M               DEALDAADRGEQVILVRDHTRPEDVSGMLAAQGIVTEIGGAASHAAVVSR
MUL_0141|M.ulcerans_Agy99           DEALDAADRGEQVILVRDHTRPEDVSGMLAAQGIVTEIGGAASHAAVVSR
Mb1158c|M.bovis_AF2122/97           DEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGAASHAAVVSR
Rv1127c|M.tuberculosis_H37Rv        DEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGAASHAAVVSR
MLBr_00955|M.leprae_Br4923          DEALDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEVGGAASHAAVVSR
MAV_1960|M.avium_104                YDAIDAAEDGQDVILVRRSTSPDDVQGMIAALGIVTGIGGTTSHAAVVSR
TH_2849|M.thermoresistible__bu      EEAQAKPGS----ILVREATSPEDVHGMIAAAAVVTEKGGSTSHAAVVSR
Mflv_4990|M.gilvum_PYR-GCK          QTPDEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDTGGMTCHAAIVAR
MSMEG_3934|M.smegmatis_MC2_155      LAPDDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVAR
Mvan_2632|M.vanbaalenii_PYR-1       IVAGADAELARLEQQAEMLSAPDEQLRFVERELPAATCDMVLRQLAAAYG
                                      .            .   : *:    :      .:  .    : * .  

MMAR_4331|M.marinum_M               ELGRVAVVG---------------------CGDGVATSLAGKRITVDGYT
MUL_0141|M.ulcerans_Agy99           ELGRVAVVG---------------------CGDGVAASLAGKRITVDGYT
Mb1158c|M.bovis_AF2122/97           ELGRVAVVG---------------------CGPGVAAALAGKEITVDGYE
Rv1127c|M.tuberculosis_H37Rv        ELGRVAVVG---------------------CGPGVAAALAGKEITVDGYE
MLBr_00955|M.leprae_Br4923          ELSRVAVVG---------------------CGQGTAVSLAGKQITVDGDK
MAV_1960|M.avium_104                ELGRPSVVG---------------------CGADVTDALAGKLITVDGTE
TH_2849|M.thermoresistible__bu      ALDTPCVVG---------------------CGEGTSSALVGKLVTVDATG
Mflv_4990|M.gilvum_PYR-GCK          ELGVPCIVG---------------------TRTGTRDLHDGTTVTVDGAR
MSMEG_3934|M.smegmatis_MC2_155      ELGVPCVVG---------------------ARSATVALAVGSMVTVDGTR
Mvan_2632|M.vanbaalenii_PYR-1       EWLLRVVIERLVRRWLGSSTGFAPVLRWLPHDPTIAMGAALARLAREHAA
                                          ::                                   :: :   

MMAR_4331|M.marinum_M               GEVREG------------------------------ILAPSAWSEDDTPE
MUL_0141|M.ulcerans_Agy99           GEVREG------------------------------ILAPSAWSEDDTPE
Mb1158c|M.bovis_AF2122/97           GEVRQG------------------------------VLALSAWSESDTPE
Rv1127c|M.tuberculosis_H37Rv        GEVRQG------------------------------VLALSAWSESDTPE
MLBr_00955|M.leprae_Br4923          GEVRQG------------------------------NLTLSAWSENETPE
MAV_1960|M.avium_104                GEVREG------------------------------ILELTAWSEDDSSD
TH_2849|M.thermoresistible__bu      GRIYPG------------------------------EIPGRATTVDDDED
Mflv_4990|M.gilvum_PYR-GCK          GEVASGVTEPAPQMTVSPRSAPAPVTAEVTGTRVYVNLAMPESAETVAAQ
MSMEG_3934|M.smegmatis_MC2_155      GEVTTGRLPETVRTTTTPQEPAPHITGEATGTKVYVNLAMPDSAEAVAAQ
Mvan_2632|M.vanbaalenii_PYR-1       AGIEPGPESAGVSEFLATFG--------HRAPDREVDLGLPRLSDDPTYV
                                    . :  *                               :     :      

MMAR_4331|M.marinum_M               LRDLTTIALK------ISPLRAHASGDYPK----------LDDP------
MUL_0141|M.ulcerans_Agy99           LRDLTTIALK------ISPLRAHASGDYPK----------LDDP------
Mb1158c|M.bovis_AF2122/97           LRELADIAQR------ISS-------------------------------
Rv1127c|M.tuberculosis_H37Rv        LRELADIAQR------ISS-------------------------------
MLBr_00955|M.leprae_Br4923          LRELADIARR------ISPLRVHMTEDHTR----------LDDS------
MAV_1960|M.avium_104                LAELTRIALA------VSPLRAHTTGDYPP----------LDAG------
TH_2849|M.thermoresistible__bu      LATLLRWARD------LAPIRVVPTADEVDGPVFDADQALIESGEELPTI
Mflv_4990|M.gilvum_PYR-GCK          PVDGVGLLRA------EFMLTEALGGRHPRDLIARGEQNMLVEKMVDSVG
MSMEG_3934|M.smegmatis_MC2_155      DVDGVGLLRA------EFMLTEALAGRHPRDLITKGEQDTLVDAMAAAVT
Mvan_2632|M.vanbaalenii_PYR-1       VELINGYLRSGALDTFETGVHEARAASDGLITGVRRVKGPVRAAVLRNLL
                                                                                      

MMAR_4331|M.marinum_M               -------------SEAGVLTAMAAGYT-----DVVSDAPLITMLNALRVQ
MUL_0141|M.ulcerans_Agy99           -------------SEAGVLTAMAAGYT-----DVVSDAPLITMLNALRVQ
Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00955|M.leprae_Br4923          -------------SDTAVRLAINTGHA-----DVVSATPLIVMMTTLRLQ
MAV_1960|M.avium_104                -------------SDDAVRAALAAGHT-----DVLSSTPLITMLTAVRLA
TH_2849|M.thermoresistible__bu      PNGTHAVSGAYFDTDEGVQAALDAGVS-----VIVSTNPLPVLLAAIAYR
Mflv_4990|M.gilvum_PYR-GCK          RIAAAFSPRPVVYRATDFRSNEFRGLTGGAEYEPVEHNPMIGFRGCYRYV
MSMEG_3934|M.smegmatis_MC2_155      RIGTAFAPRPVIYRAMDFRTNEFRGLAGGEQFEPVEHNPMIGYRGCYRYI
Mvan_2632|M.vanbaalenii_PYR-1       ARHLALGGLRERPKFDMVRAMALGRRTLRRCGAALVERGLLDDADDVFFL
                                                                                      

MMAR_4331|M.marinum_M               DGL-----------------------------------------------
MUL_0141|M.ulcerans_Agy99           DGL-----------------------------------------------
Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00955|M.leprae_Br4923          DSKDSSAKS-----------------------------------------
MAV_1960|M.avium_104                GTDTRELSR-----------------------------------------
TH_2849|M.thermoresistible__bu      KDSDD---------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          KEPELFALELEALARVRERSPNVALMIPFVRTRWELEECLSLVDASPLGR
MSMEG_3934|M.smegmatis_MC2_155      KEPDLFALELSALARAREHTPNIHLMIPFVRTRWELEECLALVDASPLRR
Mvan_2632|M.vanbaalenii_PYR-1       DGADVRAALAGRACDLRARAAADHRSFRRELRRRRVPRVLTSEGEAVYGF
                                                                                      

MMAR_4331|M.marinum_M               --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_1960|M.avium_104                --------------------------------------------------
TH_2849|M.thermoresistible__bu      --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          QRGLHRWVMAEVPSVVHWLPEYIGMGIDGVSIGSNDLTQLLLGVDRDSDV
MSMEG_3934|M.smegmatis_MC2_155      HRNLHRWVMAEVPSVVHWLPEYVGMGIDGVSIGSNDLTQLMLGVDRDSET
Mvan_2632|M.vanbaalenii_PYR-1       DTATPGAETDVLIGTALSPGVHVGTVRVLDSPVGANLQPGEVIVAASTDP
                                                                                      

MMAR_4331|M.marinum_M               --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_1960|M.avium_104                --------------------------------------------------
TH_2849|M.thermoresistible__bu      --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          CAELFDESDPAVLHAIRRIVDTANKFGITS---SLCGQAPSTNPAFAEHL
MSMEG_3934|M.smegmatis_MC2_155      CAELFDESDAAVLDAISRIISTANRLGITS---SLCGQAPSTRPEFAEHL
Mvan_2632|M.vanbaalenii_PYR-1       GWTPLFLLAGALVMEVGGVMSHGALVAREYGLPAVAGIGNAMTRLRSGQR
                                                                                      

MMAR_4331|M.marinum_M               --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_1960|M.avium_104                --------------------------------------------------
TH_2849|M.thermoresistible__bu      --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          VRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLPEDQ---------
MSMEG_3934|M.smegmatis_MC2_155      VRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPRHAPTASPRNPL-
Mvan_2632|M.vanbaalenii_PYR-1       VRVDGTAGSVTLLDSVAPDGAAEDPAPTADRAAGSGPRPAPRPRPVSPDS
                                                                                      

MMAR_4331|M.marinum_M               -
MUL_0141|M.ulcerans_Agy99           -
Mb1158c|M.bovis_AF2122/97           -
Rv1127c|M.tuberculosis_H37Rv        -
MLBr_00955|M.leprae_Br4923          -
MAV_1960|M.avium_104                -
TH_2849|M.thermoresistible__bu      -
Mflv_4990|M.gilvum_PYR-GCK          -
MSMEG_3934|M.smegmatis_MC2_155      -
Mvan_2632|M.vanbaalenii_PYR-1       R