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TDEAAPYGIVVGADGSPSSLSAVRWAATEAGLRHLRLTVAHVHEGSGADEADSVLDEATAEARNAAGVDG PDVEGRRLTGQPAAELVELSGDAQLVVVGSRGRTGRSPGSVGLGLLHHARCPVVVVHDDLAPRNRPGRRP VLVGIDGSKTSLHAAAIAFEEASRRSVDLLALHVCKDADTGGPHDHRMTILEEEAADFLRETLADLQQRF PEVVVRPLIRFANPTRQLLVQAERSQLVVVGSHGRGAIAGRLLGSVSAAVAEGCRIPVIVARRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4985 | - | - | 100% (275) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4382 | - | 4e-55 | 44.56% (294) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4999 | - | 1e-48 | 41.67% (288) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2028c | - | 1e-49 | 40.00% (295) | hypothetical protein Mb2028c |
| M. tuberculosis H37Rv | Rv2005c | - | 1e-49 | 40.00% (295) | hypothetical protein Rv2005c |
| M. leprae Br4923 | MLBr_01390 | - | 6e-07 | 30.56% (144) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_2489 | - | 1e-38 | 37.46% (299) | hypothetical protein MAB_2489 |
| M. marinum M | MMAR_5410 | - | 8e-49 | 41.83% (306) | hypothetical protein MMAR_5410 |
| M. avium 104 | MAV_2507 | - | 6e-51 | 43.79% (290) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3936 | - | 5e-51 | 43.24% (296) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 9e-51 | 42.35% (307) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_5033 | - | 6e-48 | 41.18% (306) | hypothetical protein MUL_5033 |
| M. vanbaalenii PYR-1 | Mvan_1402 | - | 7e-92 | 62.45% (277) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4985|M.gilvum_PYR-GCK --MTDEAAPYGIVVGADGSPSSLSAVRWAATEAGLRHLRLTVAHVHE---
Mvan_1402|M.vanbaalenii_PYR-1 --MPERGSPHGVVVGVDGSDCSLAAVRWAAREAHFRHARLAIVHVVT---
Mb2028c|M.bovis_AF2122/97 --MSKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVN---
Rv2005c|M.tuberculosis_H37Rv --MSKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVN---
MAV_2507|M.avium_104 --MAASSKRCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVN---
MMAR_5410|M.marinum_M --MSTESTSPAIVVGVDGSPASTLAVEWAARDAEMRNVPLKVVHVFAPM-
MUL_5033|M.ulcerans_Agy99 --MSTESTSPAIVVGVDGSPASTLAVDWAARDAEMRNVPLKVVHVFAPM-
TH_2494|M.thermoresistible__bu --VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS
MSMEG_3936|M.smegmatis_MC2_155 MSVADSDLPHGIVVGVDGSSWSRAAVRWAMAEATLRGVDLTIAHVVTPLS
MAB_2489|M.abscessus_ATCC_1997 --MTTSTPNSHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDHS-
MLBr_01390|M.leprae_Br4923 -----MGAYQTVVVGTDGSDSSLRAVDRAGKIAG----------------
::**.*** : * . *
Mflv_4985|M.gilvum_PYR-GCK -----------------GSGADEADSVLDEATAEARNAAGVDGPD-----
Mvan_1402|M.vanbaalenii_PYR-1 -----------------EGGDEEADAVLAEAMAQGRDAAGGGGSE-----
Mb2028c|M.bovis_AF2122/97 -ADVATWPPMPYPETWGVWQEDEGRQIVANAVKLAKEAVGADRKLS----
Rv2005c|M.tuberculosis_H37Rv -ADVATWPPMPYPETWGVWQEDEGRQIVANAVKLAKEAVGADRKLS----
MAV_2507|M.avium_104 -A-ATVWPQVPMAAEAVAWQEDDGRRVLQEAVKIAEDATRNGRNLA----
MMAR_5410|M.marinum_M VTPANGWADVAMPADYARWREDQAHQIVQQAHAVAVDAAAPGRAAH----
MUL_5033|M.ulcerans_Agy99 VAPANGWADVAMPADYARWREDQAHQIVQQAHAVAVDAAAPGRAAH----
TH_2494|M.thermoresistible__bu IGAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPA
MSMEG_3936|M.smegmatis_MC2_155 -ASTLLWPGGRIPEEVLEVQDNDARTAIADAIKIVQEDVTGTSRPQ----
MAB_2489|M.abscessus_ATCC_1997 --SLGQGYNLGASASFFQHLETDGAEFLSQAKDHVYALHPNVEVS-----
MLBr_01390|M.leprae_Br4923 ---------------------SDAKLIIASAYLPQHDNAR----------
:. : .:
Mflv_4985|M.gilvum_PYR-GCK ------VEGRRLTGQPAAELVELSGDAQLVVVGSRGRTGRSP---GSVGL
Mvan_1402|M.vanbaalenii_PYR-1 ------IETRRVHGRPVQALVDLSGTAQMIVVGRRGRTGRRPPGVGSVGA
Mb2028c|M.bovis_AF2122/97 ------VKSELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSS
Rv2005c|M.tuberculosis_H37Rv ------VKSELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSS
MAV_2507|M.avium_104 ------ITTELWHAPPAPTLAQLSEEAELVVVGSTGRGAIGRLLLGSVSS
MMAR_5410|M.marinum_M ------VTSEVRYAAIVPAMVELSQQAEMVVVGCRGQGGVASALLGSVSS
MUL_5033|M.ulcerans_Agy99 ------VTSEVRYAAIVPAMVELSLQAEMVVVGCRGQGGVASALLGSVSS
TH_2494|M.thermoresistible__bu GDDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRVLLGSVSS
MSMEG_3936|M.smegmatis_MC2_155 ------VRSEMLYGGVVPSLTGFSRSAELIVVGPRGRNEQHRRLLGSVAS
MAB_2489|M.abscessus_ATCC_1997 --------TVKATGRPVPVLVELSRNALMTVLGSSGLGGFTGMMAGSVSV
MLBr_01390|M.leprae_Br4923 -------------------AFDILKDESYKVTG-----------------
. *
Mflv_4985|M.gilvum_PYR-GCK GLLHHARCPVVVVHDDLAPRNRPGRRPVLVGIDGSKTSLHAAAIAFEEAS
Mvan_1402|M.vanbaalenii_PYR-1 GQLHHAHCPVAIVHDDAD-QQQP--RPVLVGVDGSKPSLAAAAIAFDEAS
Mb2028c|M.bovis_AF2122/97 SLVRRAGCPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAFDEAS
Rv2005c|M.tuberculosis_H37Rv SLVRRAGCPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAFDEAS
MAV_2507|M.avium_104 GLVRRARCPVAVIHDEDPMMPYPQRAPVLVGIDGSPASELATAIAFDEAL
MMAR_5410|M.marinum_M GLAHHAHCPVAIIHDDEALPPRSAQAPVLVGVDGSPTSELATEIAFDEAS
MUL_5033|M.ulcerans_Agy99 GLAHHAHCPVAIIHDDEPLPPRSAQAPVLVGVDGSPTSELATEIGFDEAS
TH_2494|M.thermoresistible__bu GLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEAS
MSMEG_3936|M.smegmatis_MC2_155 GLLHHARCPVAIVHATGAAR-VSGRSPVLLGTDGSPASEFATEIAFREAA
MAB_2489|M.abscessus_ATCC_1997 SLTAKGHSPVVVVR----ESPVPGGGPVVVGIDDSESSDGAAAWAFEEAA
MLBr_01390|M.leprae_Br4923 ------------------------TAPIYEILHDAKERAHAAGAKNVEE-
*: ..: *: *
Mflv_4985|M.gilvum_PYR-GCK RRSVDLLALHVCKDADTGGPH------DHRMTILEEEAADFLRETLADLQ
Mvan_1402|M.vanbaalenii_PYR-1 WRGADLLALHVCKDADAPASH------DAQTSVLEQDAEDFLTASLADLR
Mb2028c|M.bovis_AF2122/97 RRGVELIAVHAWSDVEVVELP------GLDFSAVQQEAELSLAERLAGWQ
Rv2005c|M.tuberculosis_H37Rv RRGVELIAVHAWSDVEVVELP------GLDFSAVQQEAELSLAERLAGWQ
MAV_2507|M.avium_104 RRGVDLNAVHAWSDTQVFGLP------GMDWPAVRSQAERSLAERLAGWQ
MMAR_5410|M.marinum_M RRGAELVALHAWTDMGPLDFPSINWA-PIEWSNIKDQEEEVLAERLCGWQ
MUL_5033|M.ulcerans_Agy99 RRGAELVALHAWTDMGPLDFPSINWA-PIEWSNIKDQEEEVLAERLCGWQ
TH_2494|M.thermoresistible__bu FRGVDLIALHAWSDADIADIP------TLELSAVQQSAERVLSERLAGFR
MSMEG_3936|M.smegmatis_MC2_155 LRGVDVVALHVLVDADMSGLF------AAEWSALQAVVQKPIAERLGAWE
MAB_2489|M.abscessus_ATCC_1997 MRETELVAVHVWNNIPPGYVYAYTAWSAMDSAGEQQRQEQLLAERLAGWQ
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mflv_4985|M.gilvum_PYR-GCK QRFPEVVVRPLIRFANPTRQLLVQAERSQLVVVGSHGRGAIAGRLLGSVS
Mvan_1402|M.vanbaalenii_PYR-1 QQYPEVVVHRLVRFGKPARQLLAQAERAQLVVVGSHGRGGFAGKLLGSVS
Mb2028c|M.bovis_AF2122/97 ERYPDVPVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVS
Rv2005c|M.tuberculosis_H37Rv ERYPDVPVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVS
MAV_2507|M.avium_104 ERYPDVTVHRMVVCDRPARQLIEQSESAQLTVVGSHGRGGLAGTLLGSVS
MMAR_5410|M.marinum_M ERYPDVVTHKVVVSDRPAPRLLEHAHDAQLVVVGSHGRGGFPGMLLGSVS
MUL_5033|M.ulcerans_Agy99 ERYPDVVTHKVVVSDRPAPRLLEHAHDAQLVVVGSHGRGGFPGMLLGSVS
TH_2494|M.thermoresistible__bu ERYPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVS
MSMEG_3936|M.smegmatis_MC2_155 ERYPETSVNLEIEFDRPADALIAASEGAQLVVLGSRGRGGFTGMLLGSVS
MAB_2489|M.abscessus_ATCC_1997 EKYPDVPVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFLGSTS
MLBr_01390|M.leprae_Br4923 --------RPVVGAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLGSVP
: : : ::* * *. * . :.* :***..
Mflv_4985|M.gilvum_PYR-GCK AAVAEGCRIPVIVARRT---
Mvan_1402|M.vanbaalenii_PYR-1 AAVADEARVPVIVARQP---
Mb2028c|M.bovis_AF2122/97 NAVLHAARVPVIVARQS---
Rv2005c|M.tuberculosis_H37Rv NAVLHAARVPVIVARQS---
MAV_2507|M.avium_104 NAVVHSVRMPVIVARPS---
MMAR_5410|M.marinum_M RAVINSARIPVIIARTPPNS
MUL_5033|M.ulcerans_Agy99 RAVVNSARIPVIIARTPANS
TH_2494|M.thermoresistible__bu RAVVNAVTTPVIVAR-----
MSMEG_3936|M.smegmatis_MC2_155 SAVAQEVRVPIIVARPR---
MAB_2489|M.abscessus_ATCC_1997 HALIHKASCPVLVAPRT---
MLBr_01390|M.leprae_Br4923 ANVSRRAKIDVLIVHTTH--
: :::.