For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNADVATWPPMPYPETWGVWQEDEGRQI VANAVKLAKEAVGADRKLSVKSELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSSSLVRRAG CPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAFDEASRRGVELIAVHAWSDVEVVELPGLDFSA VQQEAELSLAERLAGWQERYPDVPVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAV LHAARVPVIVARQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2005c | - | - | 100% (295) | hypothetical protein Rv2005c |
| M. tuberculosis H37Rv | Rv2623 | TB31.7 | 2e-88 | 55.25% (295) | hypothetical protein Rv2623 |
| M. tuberculosis H37Rv | Rv2026c | - | 9e-84 | 51.86% (295) | hypothetical protein Rv2026c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2028c | - | 1e-166 | 100.00% (295) | hypothetical protein Mb2028c |
| M. gilvum PYR-GCK | Mflv_4382 | - | 3e-80 | 52.80% (286) | UspA domain-containing protein |
| M. leprae Br4923 | MLBr_01390 | - | 2e-05 | 28.08% (146) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_2489 | - | 9e-51 | 40.89% (291) | hypothetical protein MAB_2489 |
| M. marinum M | MMAR_2993 | - | 1e-129 | 76.27% (295) | hypothetical protein MMAR_2993 |
| M. avium 104 | MAV_2507 | - | 1e-106 | 64.41% (295) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3940 | - | 2e-75 | 52.43% (288) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 1e-79 | 52.77% (307) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2234 | - | 1e-128 | 75.93% (295) | hypothetical protein MUL_2234 |
| M. vanbaalenii PYR-1 | Mvan_1963 | - | 2e-78 | 53.66% (287) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4382|M.gilvum_PYR-GCK MSTQPA--PLGIVVGVDGSAASRVAVDWAARDAALRQVPLTLAYVLPG--
Mvan_1963|M.vanbaalenii_PYR-1 MSTQPA--PVGIVVAVDGSDASRVAVDWAARDAAMRRIPLTLAHVLPS--
Rv2005c|M.tuberculosis_H37Rv MSKPRK--QHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNA--
Mb2028c|M.bovis_AF2122/97 MSKPRK--QHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNA--
MMAR_2993|M.marinum_M MSTLGK--RLGVVVGVDGSPASNAAVCWAARDAAMRNLPLTVVHVVNT--
MUL_2234|M.ulcerans_Agy99 MSTLGK--RLGVVVGVDGSPASNAAVCWAARDAAMRNLPLTVVHVVNT--
MAV_2507|M.avium_104 MAASSK--RCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVN---
MSMEG_3940|M.smegmatis_MC2_155 MSHNGNGAGYGMVVAVDGSAESDAAVRWAAREATLRKIPVTVMHVVEP--
TH_2494|M.thermoresistible__bu VSSTAA--YEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS
MAB_2489|M.abscessus_ATCC_1997 MTTSTP--NSHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDHS-
MLBr_01390|M.leprae_Br4923 MGAYQT-----VVVGTDGSDSSLRAVDRAGKIAGSDAKLIIASAYLPQH-
: ::*..*** : * .. * : :
Mflv_4382|M.gilvum_PYR-GCK -AAVQSWIQVPLPASFYEDEKAEATRVLADARA----------VVDAATQ
Mvan_1963|M.vanbaalenii_PYR-1 -AATQSWIQVPLPAAFFEDEKLEAERILADARA----------LVTAATE
Rv2005c|M.tuberculosis_H37Rv --DVATWPPMPYPETWGVWQEDEGRQIVANAVK----------LAKEAVG
Mb2028c|M.bovis_AF2122/97 --DVATWPPMPYPETWGVWQEDEGRQIVANAVK----------LAKEAVG
MMAR_2993|M.marinum_M --DVATWPPMPYPDTWAVWQEDEGRKVIAGAVK----------IAEESVA
MUL_2234|M.ulcerans_Agy99 --DVATWPPMPYPDTWAVWQEDEGRKVIAGAVK----------IAEDSVA
MAV_2507|M.avium_104 --AATVWPQVPMAAEAVAWQEDDGRRVLQEAVK----------IAEDATR
MSMEG_3940|M.smegmatis_MC2_155 --MIVNWPVPPVQGSVTEWQEANARNVIKHAHDT--------FVAVEESA
TH_2494|M.thermoresistible__bu IGAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPA
MAB_2489|M.abscessus_ATCC_1997 --SLGQGYNLGASASFFQHLETDGAEFLSQAKD-------------HVYA
MLBr_01390|M.leprae_Br4923 --DNARAFDILKDESYKVTGTAPIYEILHDAKER--------------AH
..: :
Mflv_4382|M.gilvum_PYR-GCK AHPLPAVTEKVLSGQPVPTLADLSR--DADMIVVGSRGMGKWERRVLGSV
Mvan_1963|M.vanbaalenii_PYR-1 GGEALTVDEVVLSGQPVAALVDLAK--DAEMLVMGSRGLGKWERRLLGSV
Rv2005c|M.tuberculosis_H37Rv ADRKLSVKSELVFSTPVPTMVEISN--EAEMVVLGSSGRGALARGLLGSV
Mb2028c|M.bovis_AF2122/97 ADRKLSVKSELVFSTPVPTMVEISN--EAEMVVLGSSGRGALARGLLGSV
MMAR_2993|M.marinum_M GDRELTIKSEIVFSLPVPTMVEMSA--EAELMVVGSSGHGALARVLLGSV
MUL_2234|M.ulcerans_Agy99 GDRELTIKSEIVFSLPVPTMVEMSA--EAELMVVGSSGHGALARVLLGSV
MAV_2507|M.avium_104 NGRNLAITTELWHAPPAPTLAQLSE--EAELVVVGSTGRGAIGRLLLGSV
MSMEG_3940|M.smegmatis_MC2_155 PDG---IRHEIRYAGIVAELVDVSK--NATMMVVGSRGLGAFGGALLGSV
TH_2494|M.thermoresistible__bu GDDAVRVVTGVVRAAPVPTLVDASK--QAKLVAVGSRGQGPLRRVLLGSV
MAB_2489|M.abscessus_ATCC_1997 LHPNVEVSTVKATGRPVPVLVELSR--NALMTVLGSSGLGGFTGMMAGSV
MLBr_01390|M.leprae_Br4923 AAGAKNVEERPVVGAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLGSV
: . . :.: : :* : .:*. * . : ***
Mflv_4382|M.gilvum_PYR-GCK SSGLVHHARCPVAVIYDEDPLIPHPAQAPVVVGIDGSPASERATAIAFDE
Mvan_1963|M.vanbaalenii_PYR-1 SSGVVHHAHCPVAVIHDVDPLIPHPAQAPVVVGVDGSPASEHATAIAFDE
Rv2005c|M.tuberculosis_H37Rv SSSLVRRAGCPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAFDE
Mb2028c|M.bovis_AF2122/97 SSSLVRRAGCPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAFDE
MMAR_2993|M.marinum_M SSSLVRRASCPVAVIRDEDPMIPDPLHAPVLVGIDGSPASELATAVAFDE
MUL_2234|M.ulcerans_Agy99 SSSLVRRASCPVAVIRDEDPMIPDPLHAPVLVGIDGSPASELATAVAFDE
MAV_2507|M.avium_104 SSGLVRRARCPVAVIHDEDPMMPYPQRAPVLVGIDGSPASELATAIAFDE
MSMEG_3940|M.smegmatis_MC2_155 SSGVIHHAHCPVAVIHGDQIRRPDP-RSPVLVGIDGSPASEDATAFAFDE
TH_2494|M.thermoresistible__bu SSGLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEE
MAB_2489|M.abscessus_ATCC_1997 SVSLTAKGHSPVVVVRES----PVPGGGPVVVGIDDSESSDGAAAWAFEE
MLBr_01390|M.leprae_Br4923 PANVSRRAKIDVLIVHTTH-------------------------------
. .: :. * ::
Mflv_4382|M.gilvum_PYR-GCK ACRRGVDLVAVHTWSDAG-------YELPGVEWTEVQPEEEMLLSERLAG
Mvan_1963|M.vanbaalenii_PYR-1 ASFRGVDLVAVHTWSDAG-------YELPGTGWAEIQPEEDMLLAERLAG
Rv2005c|M.tuberculosis_H37Rv ASRRGVELIAVHAWSDVEV------VELPGLDFSAVQQEAELSLAERLAG
Mb2028c|M.bovis_AF2122/97 ASRRGVELIAVHAWSDVEV------VELPGLDFSAVQQEAELSLAERLAG
MMAR_2993|M.marinum_M ASRRGVELIAVHAWSDQDV------VELPGLNWSTMEAEARLSLAERLAG
MUL_2234|M.ulcerans_Agy99 ASRRGVELIAVHAWSDQGV------VELPGLNWSTMEAEARLSLAERLAG
MAV_2507|M.avium_104 ALRRGVDLNAVHAWSDTQV------FGLPGMDWPAVRSQAERSLAERLAG
MSMEG_3940|M.smegmatis_MC2_155 ASRRRVDLIALHAWSDVGV------FSALGMDWHEYEDQGRELLGERLAG
TH_2494|M.thermoresistible__bu ASFRGVDLIALHAWSDADI------ADIPTLELSAVQQSAERVLSERLAG
MAB_2489|M.abscessus_ATCC_1997 AAMRETELVAVHVWNNIPPGYVYAYTAWSAMDSAGEQQRQEQLLAERLAG
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mflv_4382|M.gilvum_PYR-GCK WHERYPDVTVHRVVRRDQPARRLLEEAEKAQLLVVGSHGRGGFTGMLLGS
Mvan_1963|M.vanbaalenii_PYR-1 WQERYPDVTVHRVVCRDQPARRLLEEAAKGQLLVVGSHGRGGFGGMLLGS
Rv2005c|M.tuberculosis_H37Rv WQERYPDVPVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGS
Mb2028c|M.bovis_AF2122/97 WQERYPDVPVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGS
MMAR_2993|M.marinum_M WEERYPDVTVRRVVVCDKPAHQLVEMSQTVQLVVVGSHGRGGITGVLLGS
MUL_2234|M.ulcerans_Agy99 WEERYPDVTVRRVVVCDEPAHQLVEMSQTVQLVVVGSHGRGGITGVLLGS
MAV_2507|M.avium_104 WQERYPDVTVHRMVVCDRPARQLIEQSESAQLTVVGSHGRGGLAGTLLGS
MSMEG_3940|M.smegmatis_MC2_155 WRERYPDVRVTRQIVCDQPARWLIDGSRHAQLVVVGSHGRAGFAGMLLGS
TH_2494|M.thermoresistible__bu FRERYPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGS
MAB_2489|M.abscessus_ATCC_1997 WQEKYPDVPVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFLGS
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mflv_4382|M.gilvum_PYR-GCK VGSQIVQSSRTPVIVARTA
Mvan_1963|M.vanbaalenii_PYR-1 VGSQVVQSARGPVIVARR-
Rv2005c|M.tuberculosis_H37Rv VSNAVLHAARVPVIVARQS
Mb2028c|M.bovis_AF2122/97 VSNAVLHAARVPVIVARQS
MMAR_2993|M.marinum_M VSNAVVHAVRMPVIVARSS
MUL_2234|M.ulcerans_Agy99 VSNAVVHAVRMPVIVARSS
MAV_2507|M.avium_104 VSNAVVHSVRMPVIVARPS
MSMEG_3940|M.smegmatis_MC2_155 VGSKVARAAYSPVIVVR--
TH_2494|M.thermoresistible__bu VSRAVVNAVTTPVIVAR--
MAB_2489|M.abscessus_ATCC_1997 TSHALIHKASCPVLVAPRT
MLBr_01390|M.leprae_Br4923 -------------------