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STQPAPLGIVVGVDGSAASRVAVDWAARDAALRQVPLTLAYVLPGAAVQSWIQVPLPASFYEDEKAEATR VLADARAVVDAATQAHPLPAVTEKVLSGQPVPTLADLSRDADMIVVGSRGMGKWERRVLGSVSSGLVHHA RCPVAVIYDEDPLIPHPAQAPVVVGIDGSPASERATAIAFDEACRRGVDLVAVHTWSDAGYELPGVEWTE VQPEEEMLLSERLAGWHERYPDVTVHRVVRRDQPARRLLEEAEKAQLLVVGSHGRGGFTGMLLGSVGSQI VQSSRTPVIVARTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4382 | - | - | 100% (295) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4999 | - | 7e-75 | 50.34% (290) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4992 | - | 2e-68 | 47.12% (295) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2656 | TB31.7 | 4e-89 | 54.76% (294) | hypothetical protein Mb2656 |
| M. tuberculosis H37Rv | Rv2623 | TB31.7 | 4e-89 | 54.76% (294) | hypothetical protein Rv2623 |
| M. leprae Br4923 | MLBr_01390 | - | 1e-07 | 28.87% (142) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_2489 | - | 5e-52 | 39.80% (299) | hypothetical protein MAB_2489 |
| M. marinum M | MMAR_3477 | - | 2e-84 | 55.52% (299) | hypothetical protein MMAR_3477 |
| M. avium 104 | MAV_2507 | - | 3e-89 | 57.82% (294) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3950 | - | 2e-72 | 52.96% (287) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 5e-79 | 53.09% (307) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2234 | - | 8e-85 | 53.72% (296) | hypothetical protein MUL_2234 |
| M. vanbaalenii PYR-1 | Mvan_1963 | - | 1e-135 | 80.55% (293) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4382|M.gilvum_PYR-GCK MSTQPAPLGIVVGVDGSAASRVAVDWAARDAALRQVPLTLAYVLPGAAV-
Mvan_1963|M.vanbaalenii_PYR-1 MSTQPAPVGIVVAVDGSDASRVAVDWAARDAAMRRIPLTLAHVLPSAAT-
MMAR_3477|M.marinum_M MSAPMKHLGIVVGVDGSAASYAAVSWAARDATLRHVPLTLVHMVNQAVP-
MAV_2507|M.avium_104 MAASSKRCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVNAAT--
MUL_2234|M.ulcerans_Agy99 MSTLGKRLGVVVGVDGSPASNAAVCWAARDAAMRNLPLTVVHVVNTDVA-
TH_2494|M.thermoresistible__bu VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATSIG
Mb2656|M.bovis_AF2122/97 MSSGNSSLGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSPEVA-
Rv2623|M.tuberculosis_H37Rv MSSGNSSLGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSPEVA-
MSMEG_3950|M.smegmatis_MC2_155 MVQSATEYGILVGVDSSAESDAAVRWAAREASLHDAPITLMHVIAPVVV-
MAB_2489|M.abscessus_ATCC_1997 MTTSTPNSHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDHSSLG
MLBr_01390|M.leprae_Br4923 ---MGAYQTVVVGTDGSDSSLRAVDRAGKIAGSDAKLIIASAYLPQHDN-
::*. *.* : *: *. * : :
Mflv_4382|M.gilvum_PYR-GCK --QSWIQVPLPASFYEDEKAEATRVLADARAVVDAATQAHPL--------
Mvan_1963|M.vanbaalenii_PYR-1 --QSWIQVPLPAAFFEDEKLEAERILADARALVTAATEGGEA--------
MMAR_3477|M.marinum_M ---MWPEMPMMTSMSAWQEEDGRQVLEQAGKIAQEVTQQGRD--------
MAV_2507|M.avium_104 ---VWPQVPMAAEAVAWQEDDGRRVLQEAVKIAEDATRNGRN--------
MUL_2234|M.ulcerans_Agy99 ---TWPPMPYPDTWAVWQEDEGRKVIAGAVKIAEDSVAGDRE--------
TH_2494|M.thermoresistible__bu APLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPAGD
Mb2656|M.bovis_AF2122/97 ---TWLEVPLPPGVLRWQQDHGRHLIDDALKVVEQASLRAGP--------
Rv2623|M.tuberculosis_H37Rv ---TWLEVPLPPGVLRWQQDHGRHLIDDALKVVEQASLRAGP--------
MSMEG_3950|M.smegmatis_MC2_155 ---SWPAGPYMATVLECQEENARHAIEQAQKVVADCLGETHG--------
MAB_2489|M.abscessus_ATCC_1997 ---QGYNLGASASFFQHLETDGAEFLSQAKDHVYALHPN-----------
MLBr_01390|M.leprae_Br4923 --ARAFDILKDESYKVTGTAPIYEILHDAKERAHAAGAKN----------
. : : .
Mflv_4382|M.gilvum_PYR-GCK --PAVTEKVLSGQPVPTLADLSR--DADMIVVGSRGMGKWERRVLGSVSS
Mvan_1963|M.vanbaalenii_PYR-1 --LTVDEVVLSGQPVAALVDLAK--DAEMLVMGSRGLGKWERRLLGSVSS
MMAR_3477|M.marinum_M --TQIKSELRWSAPVPTFVELSQ--EADLVVVGSHGRGAVARGLLGSVSS
MAV_2507|M.avium_104 --LAITTELWHAPPAPTLAQLSE--EAELVVVGSTGRGAIGRLLLGSVSS
MUL_2234|M.ulcerans_Agy99 --LTIKSEIVFSLPVPTMVEMSA--EAELMVVGSSGHGALARVLLGSVSS
TH_2494|M.thermoresistible__bu DAVRVVTGVVRAAPVPTLVDASK--QAKLVAVGSRGQGPLRRVLLGSVSS
Mb2656|M.bovis_AF2122/97 --PTVHSEIVPAAAVPTLVDMSK--DAVLMVVGCLGSGRWPGRLLGSVSS
Rv2623|M.tuberculosis_H37Rv --PTVHSEIVPAAAVPTLVDMSK--DAVLMVVGCLGSGRWPGRLLGSVSS
MSMEG_3950|M.smegmatis_MC2_155 --LTVQTEIRKESVARTLIDASK--SAQMVVVGNRGMGALGRVLLGSTST
MAB_2489|M.abscessus_ATCC_1997 --VEVSTVKATGRPVPVLVELSR--NALMTVLGSSGLGGFTGMMAGSVSV
MLBr_01390|M.leprae_Br4923 ----VEERPVVGAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLGSVPA
: . .: : : .* : .:* * . : **..
Mflv_4382|M.gilvum_PYR-GCK GLVHHARCPVAVIYDEDPLIPHP---AQAPVVVGIDGSPASERATAIAFD
Mvan_1963|M.vanbaalenii_PYR-1 GVVHHAHCPVAVIHDVDPLIPHP---AQAPVVVGVDGSPASEHATAIAFD
MMAR_3477|M.marinum_M GVVHRAHCPVAVIRDEDPEAPQPEDRDRAPVVVGIDGSSASELATAIAFD
MAV_2507|M.avium_104 GLVRRARCPVAVIHDEDPMMPYP---QRAPVLVGIDGSPASELATAIAFD
MUL_2234|M.ulcerans_Agy99 SLVRRASCPVAVIRDEDPMIPDP---LHAPVLVGIDGSPASELATAVAFD
TH_2494|M.thermoresistible__bu GLVHHAHCPVAVIREGTPHTPDF---AKRPVLVGIDGSESAQRATAVAFE
Mb2656|M.bovis_AF2122/97 GLLRHAHCPVVIIHDEDSVMPHP---QQAPVLVGVDGSSASELATAIAFD
Rv2623|M.tuberculosis_H37Rv GLLRHAHCPVVIIHDEDSVMPHP---QQAPVLVGVDGSSASELATAIAFD
MSMEG_3950|M.smegmatis_MC2_155 SLLHYASGPVVVVHGDDQAAHDS----RLPVLLGIDGSPASEVATSHAFD
MAB_2489|M.abscessus_ATCC_1997 SLTAKGHSPVVVVRES----PVP---GGGPVVVGIDDSESSDGAAAWAFE
MLBr_01390|M.leprae_Br4923 NVSRRAKIDVLIVHTTH---------------------------------
.: . * ::
Mflv_4382|M.gilvum_PYR-GCK EACRRGVDLVAVHTWSDAG-------YELPGVEWTEVQPEEEMLLSERLA
Mvan_1963|M.vanbaalenii_PYR-1 EASFRGVDLVAVHTWSDAG-------YELPGTGWAEIQPEEDMLLAERLA
MMAR_3477|M.marinum_M EASRRGVELKAVHAWSDLEV------VDLPGLDWSTVKGEAEETLAERLA
MAV_2507|M.avium_104 EALRRGVDLNAVHAWSDTQV------FGLPGMDWPAVRSQAERSLAERLA
MUL_2234|M.ulcerans_Agy99 EASRRGVELIAVHAWSDQGV------VELPGLNWSTMEAEARLSLAERLA
TH_2494|M.thermoresistible__bu EASFRGVDLIALHAWSDADI------ADIPTLELSAVQQSAERVLSERLA
Mb2656|M.bovis_AF2122/97 EASRRNVDLVALHAWSDVDV------SEWPGIDWPATQSMAEQVLAERLA
Rv2623|M.tuberculosis_H37Rv EASRRNVDLVALHAWSDVDV------SEWPGIDWPATQSMAEQVLAERLA
MSMEG_3950|M.smegmatis_MC2_155 EASRRGVDLVALHVWIDVGD------IPPIGPTWEEQEETGRALLAERLA
MAB_2489|M.abscessus_ATCC_1997 EAAMRETELVAVHVWNNIPPGYVYAYTAWSAMDSAGEQQRQEQLLAERLA
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mflv_4382|M.gilvum_PYR-GCK GWHERYPDVTVHRVVRRDQPARRLLEEAEKAQLLVVGSHGRGGFTGMLLG
Mvan_1963|M.vanbaalenii_PYR-1 GWQERYPDVTVHRVVCRDQPARRLLEEAAKGQLLVVGSHGRGGFGGMLLG
MMAR_3477|M.marinum_M GWQERYPDVTVDRVVVCDRPARQLIDQAQTAQLVVLGSHGRGGFTSMLVG
MAV_2507|M.avium_104 GWQERYPDVTVHRMVVCDRPARQLIEQSESAQLTVVGSHGRGGLAGTLLG
MUL_2234|M.ulcerans_Agy99 GWEERYPDVTVRRVVVCDEPAHQLVEMSQTVQLVVVGSHGRGGITGVLLG
TH_2494|M.thermoresistible__bu GFRERYPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLG
Mb2656|M.bovis_AF2122/97 GWQERYPNVAITRVVVRDQPARQLVQRSEEAQLVVVGSRGRGGYAGMLVG
Rv2623|M.tuberculosis_H37Rv GWQERYPNVAITRVVVRDQPARQLVQRSEEAQLVVVGSRGRGGYAGMLVG
MSMEG_3950|M.smegmatis_MC2_155 GWQERYPDVKVHRRVERAQPAYWLLEEAKQAQLVVVGSHGRGGFTGMLLG
MAB_2489|M.abscessus_ATCC_1997 GWQEKYPDVPVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFLG
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mflv_4382|M.gilvum_PYR-GCK SVGSQIVQSSRTPVIVARTA--
Mvan_1963|M.vanbaalenii_PYR-1 SVGSQVVQSARGPVIVARR---
MMAR_3477|M.marinum_M STSNAVLHAVHTPVIVARSA--
MAV_2507|M.avium_104 SVSNAVVHSVRMPVIVARPS--
MUL_2234|M.ulcerans_Agy99 SVSNAVVHAVRMPVIVARSS--
TH_2494|M.thermoresistible__bu SVSRAVVNAVTTPVIVAR----
Mb2656|M.bovis_AF2122/97 SVGETVAQLARTPVIVARESLT
Rv2623|M.tuberculosis_H37Rv SVGETVAQLARTPVIVARESLT
MSMEG_3950|M.smegmatis_MC2_155 SVSSRVAQSATTPVMVVRPR--
MAB_2489|M.abscessus_ATCC_1997 STSHALIHKASCPVLVAPRT--
MLBr_01390|M.leprae_Br4923 ----------------------