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SVADSDLPHGIVVGVDGSSWSRAAVRWAMAEATLRGVDLTIAHVVTPLSASTLLWPGGRIPEEVLEVQDN DARTAIADAIKIVQEDVTGTSRPQVRSEMLYGGVVPSLTGFSRSAELIVVGPRGRNEQHRRLLGSVASGL LHHARCPVAIVHATGAARVSGRSPVLLGTDGSPASEFATEIAFREAALRGVDVVALHVLVDADMSGLFAA EWSALQAVVQKPIAERLGAWEERYPETSVNLEIEFDRPADALIAASEGAQLVVLGSRGRGGFTGMLLGSV SSAVAQEVRVPIIVARPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3936 | - | - | 100% (299) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3950 | - | 3e-65 | 46.46% (297) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3940 | - | 9e-62 | 45.89% (292) | universal stress protein family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2051c | - | 1e-69 | 46.71% (289) | hypothetical protein Mb2051c |
| M. gilvum PYR-GCK | Mflv_4382 | - | 7e-65 | 47.24% (290) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2026c | - | 1e-69 | 46.71% (289) | hypothetical protein Rv2026c |
| M. leprae Br4923 | MLBr_01390 | - | 5e-05 | 28.68% (136) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_2489 | - | 9e-35 | 33.56% (292) | hypothetical protein MAB_2489 |
| M. marinum M | MMAR_4922 | - | 6e-69 | 48.48% (297) | hypothetical protein MMAR_4922 |
| M. avium 104 | MAV_2507 | - | 2e-65 | 45.33% (289) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 3e-67 | 46.15% (299) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_0483 | - | 1e-68 | 48.15% (297) | hypothetical protein MUL_0483 |
| M. vanbaalenii PYR-1 | Mvan_1963 | - | 2e-60 | 45.17% (290) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4382|M.gilvum_PYR-GCK --MSTQPAPLGIVVGVDGSAASRVAVDWAARDAALRQVPLTLAYVLPGAA
Mvan_1963|M.vanbaalenii_PYR-1 --MSTQPAPVGIVVAVDGSDASRVAVDWAARDAAMRRIPLTLAHVLPSAA
MMAR_4922|M.marinum_M --MGGEVVDPGIVIGIDGSPGSDAALKWAVQEATMRNVALTVVHAAAYVP
MUL_0483|M.ulcerans_Agy99 --MGGEVVDPGIVIGIDGSPGSDAALKWAVQEATMRNVALTVVHAAAYVP
MSMEG_3936|M.smegmatis_MC2_155 MSVADSDLPHGIVVGVDGSSWSRAAVRWAMAEATLRGVDLTIAHVVT--P
Mb2051c|M.bovis_AF2122/97 --MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVV
Rv2026c|M.tuberculosis_H37Rv --MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVV
MAV_2507|M.avium_104 --MAASSKRCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVNAAT
TH_2494|M.thermoresistible__bu --VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS
MAB_2489|M.abscessus_ATCC_1997 --MTTSTPNSHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDHSS
MLBr_01390|M.leprae_Br4923 -----MGAYQTVVVGTDGSDSSLRAVDRAGKIAG-SDAKLIIA-------
:::. *** : *: * * : :
Mflv_4382|M.gilvum_PYR-GCK VQS----WIQVPLPASFYEDEKAEATRVLADARAVVD-AATQAHPLP---
Mvan_1963|M.vanbaalenii_PYR-1 TQS----WIQVPLPAAFFEDEKLEAERILADARALVT-AATEGGEAL---
MMAR_4922|M.marinum_M DAAPKVEWFGDPAPDELLQQLDTRAQQVLADAVQIVK-DATGDHRL----
MUL_0483|M.ulcerans_Agy99 YAAPKVEWFGDPAPDELLQQLDTRAQQVLADAVQIVK-DATGDHRL----
MSMEG_3936|M.smegmatis_MC2_155 LSASTLLWPGGRIPEEVLEVQDNDARTAIADAIKIVQEDVTGTSRP----
Mb2051c|M.bovis_AF2122/97 VG-----WPVGQLYANMTEWQKDNAQQVIEQAREALT-NSLGESKPP---
Rv2026c|M.tuberculosis_H37Rv VG-----WPVGQLYANMTEWQKDNAQQVIEQAREALT-NSLGESKPP---
MAV_2507|M.avium_104 V------WPQVPMAAEAVAWQEDDGRRVLQEAVKIAE-DATRNGRNL---
TH_2494|M.thermoresistible__bu IGA-PLVWPAGPIPDSLIQWQEDEARQILADSAEIAE-NAFQEARAAGPG
MAB_2489|M.abscessus_ATCC_1997 LGQG----YNLGASASFFQHLETDGAEFLSQAKDHVY--ALHPN------
MLBr_01390|M.leprae_Br4923 -------------SAYLPQHDNARAFDILKDESYKVT-------------
. . : :
Mflv_4382|M.gilvum_PYR-GCK -------AVTEKVLSGQPVPTLADLSRDADMIVVGSRGMGKWERRVLGSV
Mvan_1963|M.vanbaalenii_PYR-1 -------TVDEVVLSGQPVAALVDLAKDAEMLVMGSRGLGKWERRLLGSV
MMAR_4922|M.marinum_M -------RIIHELSSQSPVPALVELSRKADLVVVGSRGQGLVKRMLLGSV
MUL_0483|M.ulcerans_Agy99 -------RIIHELSSQSPVPALVELSRKADLVVVGSRGQGLVKRMLLGWV
MSMEG_3936|M.smegmatis_MC2_155 -------QVRSEMLYGGVVPSLTGFSRSAELIVVGPRGRNEQHRRLLGSV
Mb2051c|M.bovis_AF2122/97 -------QVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRLLLGSI
Rv2026c|M.tuberculosis_H37Rv -------QVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRLLLGSI
MAV_2507|M.avium_104 -------AITTELWHAPPAPTLAQLSEEAELVVVGSTGRGAIGRLLLGSV
TH_2494|M.thermoresistible__bu PAGDDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRVLLGSV
MAB_2489|M.abscessus_ATCC_1997 ------VEVSTVKATGRPVPVLVELSRNALMTVLGSSGLGGFTGMMAGSV
MLBr_01390|M.leprae_Br4923 -----------------GTAPIYEILHDAKERAHAAGAKNVEERPVVGAP
.. : ..* . .. . . : *
Mflv_4382|M.gilvum_PYR-GCK SSGLVHHARCPVAVIYDEDPLIPHPAQAPVVVGIDGSPASERATAIAFDE
Mvan_1963|M.vanbaalenii_PYR-1 SSGVVHHAHCPVAVIHDVDPLIPHPAQAPVVVGVDGSPASEHATAIAFDE
MMAR_4922|M.marinum_M STGLVHHAHCPVAVVPSEVPPPVEG---PVVVGIDGSPASELATAIAFDE
MUL_0483|M.ulcerans_Agy99 STGLVHHAHCPVAVVPSEVPPPVEG---PVVVGIDGSPASELATAIAFDE
MSMEG_3936|M.smegmatis_MC2_155 ASGLLHHARCPVAIVHATGAARVSGR-SPVLLGTDGSPASEFATEIAFRE
Mb2051c|M.bovis_AF2122/97 STALLHHARCPVAIIHSGNGATPDSD-APVLVGIDGSPASEAATALAFDE
Rv2026c|M.tuberculosis_H37Rv STALLHHARCPVAIIHSGNGATPDSD-APVLVGIDGSPASEAATALAFDE
MAV_2507|M.avium_104 SSGLVRRARCPVAVIHDEDPMMPYPQRAPVLVGIDGSPASELATAIAFDE
TH_2494|M.thermoresistible__bu SSGLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEE
MAB_2489|M.abscessus_ATCC_1997 SVSLTAKGHSPVVVVRES----PVPGGGPVVVGIDDSESSDGAAAWAFEE
MLBr_01390|M.leprae_Br4923 VDALVN--------------------------------------------
.:
Mflv_4382|M.gilvum_PYR-GCK ACRRGVDLVAVHTWSDAGY---------ELPGVEWTEVQPEEEMLLSERL
Mvan_1963|M.vanbaalenii_PYR-1 ASFRGVDLVAVHTWSDAGY---------ELPGTGWAEIQPEEDMLLAERL
MMAR_4922|M.marinum_M ASWRGAELVALHAWTDAEVPAAANRDWTGTTRTSWSELQAAADETLAERL
MUL_0483|M.ulcerans_Agy99 ASWRGAELVALHAWTDAEIPAAANRDWTGTTRTSWSELQAATDETLAERL
MSMEG_3936|M.smegmatis_MC2_155 AALRGVDVVALHVLVDADM--------SGLFAAEWSALQAVVQKPIAERL
Mb2051c|M.bovis_AF2122/97 ASRRRVDLVALHAWTDLGM--------FPVLGMDWREREKREAEVLAERL
Rv2026c|M.tuberculosis_H37Rv ASRRRVDLVALHAWTDLGM--------FPVLGMDWREREKREAEVLAERL
MAV_2507|M.avium_104 ALRRGVDLNAVHAWSDTQV--------FGLPGMDWPAVRSQAERSLAERL
TH_2494|M.thermoresistible__bu ASFRGVDLIALHAWSDADI--------ADIPTLELSAVQQSAERVLSERL
MAB_2489|M.abscessus_ATCC_1997 AAMRETELVAVHVWNNIPPG--YVYAYTAWSAMDSAGEQQRQEQLLAERL
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mflv_4382|M.gilvum_PYR-GCK AGWHERYPDVTVHRVVRRDQPARRLLEEAEKAQLLVVGSHGRGGFTGMLL
Mvan_1963|M.vanbaalenii_PYR-1 AGWQERYPDVTVHRVVCRDQPARRLLEEAAKGQLLVVGSHGRGGFGGMLL
MMAR_4922|M.marinum_M VGWRERYPDVVVRRVVVVNRATQHLIEHAESAQLVVVGSHGRGGFSGMLL
MUL_0483|M.ulcerans_Agy99 VGWRERYPDVVVRRVVVVNRVTQHLIEHAESAQLVVVGSHGRGGFSGMLL
MSMEG_3936|M.smegmatis_MC2_155 GAWEERYPETSVNLEIEFDRPADALIAASEGAQLVVLGSRGRGGFTGMLL
Mb2051c|M.bovis_AF2122/97 AGWQEQYPDVRVHRSLVCDKPARWLLEHSEQAQLVVVGSHGRGGFSGMLL
Rv2026c|M.tuberculosis_H37Rv AGWQEQYPDVRVHRSLVCDKPARWLLEHSEQAQLVVVGSHGRGGFSGMLL
MAV_2507|M.avium_104 AGWQERYPDVTVHRMVVCDRPARQLIEQSESAQLTVVGSHGRGGLAGTLL
TH_2494|M.thermoresistible__bu AGFRERYPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLL
MAB_2489|M.abscessus_ATCC_1997 AGWQEKYPDVPVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFL
MLBr_01390|M.leprae_Br4923 -------------------------LAEKTNADLLVVGNVGLSTIAGRLL
: .:* * *. * . : * :*
Mflv_4382|M.gilvum_PYR-GCK GSVGSQIVQSSRTPVIVARTA-
Mvan_1963|M.vanbaalenii_PYR-1 GSVGSQVVQSARGPVIVARR--
MMAR_4922|M.marinum_M GSVSTAVVHAVRAPVIVARQG-
MUL_0483|M.ulcerans_Agy99 GSVSTAVVHAVRAPVIVARQG-
MSMEG_3936|M.smegmatis_MC2_155 GSVSSAVAQEVRVPIIVARPR-
Mb2051c|M.bovis_AF2122/97 GSVSSAVAHSVRIPVIVVRPS-
Rv2026c|M.tuberculosis_H37Rv GSVSSAVAHSVRIPVIVVRPS-
MAV_2507|M.avium_104 GSVSNAVVHSVRMPVIVARPS-
TH_2494|M.thermoresistible__bu GSVSRAVVNAVTTPVIVAR---
MAB_2489|M.abscessus_ATCC_1997 GSTSHALIHKASCPVLVAPRT-
MLBr_01390|M.leprae_Br4923 GSVPANVSRRAKIDVLIVHTTH
**. : . :::.