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TSNFGELRSYRRSALRDDTQAGLSVAAYLVPQALAYATLAGLSPAAGLWAALPPLLVYAILGSSRQLSVG PESTTALMTAAVLAPVVGGDDPVRYAASAAVLAILVGLVCLGAGMLRLGYLANMLSKPVLVGYMLGVALA MVAGQLGRIAGVEVTGDTVPAQLAAFAAAVDGVHWPTAGLALGVLVLVLTMERVAPTLPAPLIGVVVATV VTWAGELTRFGVAVVGDVPVGLPAPALPWLTVDQIQALIVPAIGISVVAFSDNILTARAFASRAGQNIDP NTELRALGVSNLAVGFLRGFPVSSSASRTALAAAAGARTQMYSLVVLAVVAVVVVFGGGLVSHVPAAALG GLIVYAALKLVDVRSFRALARFRRSEVVLAALTAIAVTVFGLLYGVVIAVALSVLDLLRRLSHAHDSVQG LVPGLAGMHDVDDYPDARIVPGLVVYRYDAPLCFANAEDFRRRALEAIDQMDQPTRWFVLNAEANVEVDM TAIEALDQVRQDCLRRGIVFAMARVKQDLREALAAGGVLDEIGQDRLYMTLPTAVAAYQAWVASGNKG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4975 | - | - | 100% (559) | sulfate transporter |
| M. gilvum PYR-GCK | Mflv_1119 | - | 6e-47 | 28.65% (541) | sulphate transporter |
| M. gilvum PYR-GCK | Mflv_0188 | - | 3e-09 | 25.07% (335) | uracil-xanthine permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1768c | - | 0.0 | 60.66% (544) | sulphate-transport transmembrane protein ABC transporter |
| M. tuberculosis H37Rv | Rv1739c | - | 0.0 | 60.48% (544) | sulphate-transport transmembrane protein ABC transporter |
| M. leprae Br4923 | MLBr_02279 | - | 2e-25 | 26.55% (403) | putative transmembrane transport protein |
| M. abscessus ATCC 19977 | MAB_4448 | - | 7e-48 | 27.82% (532) | putative sulfate transporter |
| M. marinum M | MMAR_4750 | - | 3e-31 | 24.76% (521) | integral membrane transporter |
| M. avium 104 | MAV_0121 | - | 3e-26 | 26.25% (400) | carbonate dehydratase |
| M. smegmatis MC2 155 | MSMEG_6453 | - | 1e-51 | 29.12% (546) | sulfate permease |
| M. thermoresistible (build 8) | TH_2104 | - | 1e-47 | 28.67% (565) | sulfate permease |
| M. ulcerans Agy99 | MUL_0321 | - | 3e-32 | 24.86% (527) | integral membrane transporter |
| M. vanbaalenii PYR-1 | Mvan_1430 | - | 0.0 | 72.60% (551) | sulfate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6453|M.smegmatis_MC2_155 ----------MLANLARLLPHKNDYTDVPRTWRQDVLAGITVGVVALPLA
TH_2104|M.thermoresistible__bu ------VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLA
MMAR_4750|M.marinum_M ---------------------MLAALRSPTRLRTEVLAGLVVALALIPEA
MUL_0321|M.ulcerans_Agy99 MSSQQVSAVPTIRKAGDPSTAVLAALRSPTRLRTEVLAGLVVALALIPEA
MLBr_02279|M.leprae_Br4923 ---------------------------MRSAIRYDLPASLVVFLVALPLS
MAV_0121|M.avium_104 -------------------MSTSRSERLREVLRYDLPASLVVFLVALPLS
Mflv_4975|M.gilvum_PYR-GCK ----------------MTSNFGELRSYRRSALRDDTQAGLSVAAYLVPQA
Mvan_1430|M.vanbaalenii_PYR-1 ------------MLTRWAPGLAGLREGRGAPLRVDLLAGLSVSAYLIPQA
Mb1768c|M.bovis_AF2122/97 -------MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQA
Rv1739c|M.tuberculosis_H37Rv -------MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQA
MAB_4448|M.abscessus_ATCC_1997 ----------------MPSAPGLFESYDAIKARRDVIAGLTVAAISLPQA
* : *.: * :* :
MSMEG_6453|M.smegmatis_MC2_155 LAFGISSGVGAAAGLITAVVAGLVAAVFGGSHVQVSGPTGAMAVVLAPIV
TH_2104|M.thermoresistible__bu LAFGISSGVGAAAGLITAVVAGLVAAVFGGSHIQVSGPTGAMAVILAPIV
MMAR_4750|M.marinum_M ISFSIIAGVDPRVGLFASFTMAVTIAVVGGRPAMISAATGAIALVIAPLA
MUL_0321|M.ulcerans_Agy99 ISFSIIAGVDPRVGLFASFTMAVTIAVVGGRLAMISAATGAIALVIAPLA
MLBr_02279|M.leprae_Br4923 LGIAIASDTPVLAGLIAAIVGGIVAGALGGSPLQVSGPAAGLTVVIADLI
MAV_0121|M.avium_104 LGIAIASDAPVLAGLIAAIVGGIVGGWLGGSPLQVSGPAAGLTVVVADVV
Mflv_4975|M.gilvum_PYR-GCK LAYATLAGLSPAAGLWAALPPLLVYAILGSSRQLSVGPESTTALMTAAVL
Mvan_1430|M.vanbaalenii_PYR-1 LAYAALAGLSPIVGLWAALPPLLIYAILGSSRQLSVGPESTTSLMTAAVL
Mb1768c|M.bovis_AF2122/97 MAYATVAGLPPAAGLWASIAPLAIYALLGSSRQLSIGPESATALMTAAVL
Rv1739c|M.tuberculosis_H37Rv MAYATVAGLPPAAGLWASIAPLAIYALLGSSRQLSIGPESATALMTAAVL
MAB_4448|M.abscessus_ATCC_1997 MAYALIAGVDPKYGVYSAIVVTAIASIFGSSSHLINGPTSAISLLVFSSL
:. . :. *: ::. . .*. .. . :::
MSMEG_6453|M.smegmatis_MC2_155 AEHGLG--------SIALVTVLAGLLVLAAGITGLGRAVTFIPWPVIEGF
TH_2104|M.thermoresistible__bu AQHGLT--------SIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIEGF
MMAR_4750|M.marinum_M REHGAD--------YFIAAVILAGLVQITLSLLGVARLMRFIPRSVMVGF
MUL_0321|M.ulcerans_Agy99 REQGAD--------YFIAAVILAGLVQITLSLLGVARLMRFIPRSVMVGF
MLBr_02279|M.leprae_Br4923 SDFGWG--------VTCFITVAAGVLQVLLGLSRVARAALAISPVVVHAM
MAV_0121|M.avium_104 AEFGWG--------VTCFITVVAGVLQVLLGFSRIARAALAISPVVVHAM
Mflv_4975|M.gilvum_PYR-GCK APVVGGDDPVRYAASAAVLAILVGLVCLGAGMLRLGYLANMLSKPVLVGY
Mvan_1430|M.vanbaalenii_PYR-1 VPLVGGNDPVRYATYAAILAILVGVLCLAAGIIGLGYLANLLSKPVLVGY
Mb1768c|M.bovis_AF2122/97 APMAAG-DLRRYAVLAATLGLLVGLICLLAGTARLGFLASLLSRPVLVGY
Rv1739c|M.tuberculosis_H37Rv APMAAG-DLRRYAVLAATLGLLVGLICLLAGTARLGFLASLRSRPVLVGY
MAB_4448|M.abscessus_ATCC_1997 AFLDPE-NRTGLFEALFLLGVLVGTIQILIAVFKLGDLTRYISESVVIGF
: .* : : . :. . *: .
MSMEG_6453|M.smegmatis_MC2_155 TLGIAAIIFLQQVPAALAQQAPSGE-RTLLAAFTVVRNADWGEAAKTLAV
TH_2104|M.thermoresistible__bu TLGIAAIIFLQQVPAAFATEAPAGQ-RTLVAAWHVVTHADWTAAVKTLSV
MMAR_4750|M.marinum_M VNALAILIFLSQLPHLLGVPP------------------------VVYPF
MUL_0321|M.ulcerans_Agy99 VNALAILIFLSQVPHLLGVPA------------------------VVYPF
MLBr_02279|M.leprae_Br4923 LAGVGITIALQQAHVLLGGKSKSTA-WHNAIGLPSQILGAHRPGVILGVL
MAV_0121|M.avium_104 LAGIGITIALQQVHVLLGGSSKSSA-WSNVTGLPAQILGAHRPGLVLGLL
Mflv_4975|M.gilvum_PYR-GCK MLGVALAMVAGQLGRIAGVEVTGD---TVPAQLAAFAAAVDGVHWPTAGL
Mvan_1430|M.vanbaalenii_PYR-1 LFGIAIAMVTGQLERISGVPVSGE---SVVEQVRAFASGIGQVHWPTLMM
Mb1768c|M.bovis_AF2122/97 MAGIALVMISSQLGTITGTSVEGN---EFFSEVHSFATSVTRVHWPTFVL
Rv1739c|M.tuberculosis_H37Rv MAGIALVMISSQLGTITGTSVEGN---EFFSEVHSFATSVTRVHWPTFVL
MAB_4448|M.abscessus_ATCC_1997 MASAALLLAIGQLANAIGVRDKGDGHMQVLQRAWLTLFHGDAVNYRALFL
. . : * . .
MSMEG_6453|M.smegmatis_MC2_155 VGVVAVLMIVLPRVHSGIPASLTAVIVATVLIVALDIPV----------A
TH_2104|M.thermoresistible__bu VSLVALLMVVLPRLHRSIPESLTAVVAATVIVTVFGISV----------A
MMAR_4750|M.marinum_M VIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEI----------P
MUL_0321|M.ulcerans_Agy99 VIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEI----------L
MLBr_02279|M.leprae_Br4923 VITILIAWRWVPARVARIPGPLVAIVVTTLVSVVFPFHV----------S
MAV_0121|M.avium_104 VIAILVAWRWVPARLAIVPGPLVAIVVVTIISMVLPFKV----------S
Mflv_4975|M.gilvum_PYR-GCK ALGVLVLVLTMERVAPTLPAPLIGVVVATVVTWAGELTR----------F
Mvan_1430|M.vanbaalenii_PYR-1 AAAVLLCVVAVERAAPRLPGPLIAVLGAAAVVAVWSLTR----------Y
Mb1768c|M.bovis_AF2122/97 AMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDA----------K
Rv1739c|M.tuberculosis_H37Rv AMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDA----------K
MAB_4448|M.abscessus_ATCC_1997 SVTAVALAVLLRRLVQRYELPQIDMLLVLIVTAVIAYAYGWTVPDGTGHT
: . :: .
MSMEG_6453|M.smegmatis_MC2_155 TIG---ELPSHLPAPVLPHV--DVNTLRTMFSAALAIAALAAIESLLSAR
TH_2104|M.thermoresistible__bu TIG---ELPSQLPTPVLPQA--DMGAMQTLLGAALAIAALAAIESLLSAR
MMAR_4750|M.marinum_M NVGDEGQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLTAK
MUL_0321|M.ulcerans_Agy99 NVGDEGQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLTAK
MLBr_02279|M.leprae_Br4923 RIQ--VDNRSSLDVLQLPKLP--DGHWGAVVLGVITVALIASVESLLSAV
MAV_0121|M.avium_104 RIE--LDG-SVLDAVRLPSLP--HGNWGAVAIAVITVTLITSVQSLLTAV
Mflv_4975|M.gilvum_PYR-GCK GVAVVGDVPVGLPAPALPWLT--VDQIQALIVPAIGISVVAFSDNILTAR
Mvan_1430|M.vanbaalenii_PYR-1 GIDVVGAIPAGAPSPAVPVLA--DVPVRELLMAAVGIAVVAFSDNILTAR
Mb1768c|M.bovis_AF2122/97 GIAIVGRIPSGLPTPGVPPVS--VEDLRALIIPAAGIAIVTFTDGVLTAR
Rv1739c|M.tuberculosis_H37Rv GIAIVGRIPSGLPTPGVPPVS--VEDLRALIIPAAGIAIVTFTDGVLTAR
MAB_4448|M.abscessus_ATCC_1997 DVKISGKIPASLPEFHIPEVQ--VSTLGELSHGALAIAFIGLIEALSIAK
: :* : . :: : : : *
MSMEG_6453|M.smegmatis_MC2_155 VAATMSPTGPYDPNRELVGQGLASVASGAFGGMPATGAIARTAVNVRS-G
TH_2104|M.thermoresistible__bu VAATMSATGPYHPDRELVGQGMASVASGLFGGMPATGAIARTAVNVRS-G
MMAR_4750|M.marinum_M LVDDITDTHSN-KTREAWGQGVANVVTGFFGGMGGCAMIGQTMINVKVSG
MUL_0321|M.ulcerans_Agy99 LVDDITDTHSN-KTREAWGQGVANVVTGFFGGMGGCAMIGQTMINVKVPG
MLBr_02279|M.leprae_Br4923 SLDKMHNGPRTDLNRELIGQGAANIVSGAIGGLPITGVIVRSSTNVIA-G
MAV_0121|M.avium_104 SIDRMHTGPRTDFNRELIGQGAANIASGALGGLPIAGVIVRSSANVNA-G
Mflv_4975|M.gilvum_PYR-GCK AFASRA-GQNIDPNTELRALGVSNLAVGFLRGFPVSSSASRTALAAAA-G
Mvan_1430|M.vanbaalenii_PYR-1 AFAARV-GETVDANAELRALGVSNIAVGFLRGFPVSSSGSRTALAAAA-G
Mb1768c|M.bovis_AF2122/97 AFAARR-GQEVNANAELRAVGACNIAAGLTHGFPVSSSSSRTALADVV-G
Rv1739c|M.tuberculosis_H37Rv AFAARR-GQEVNANAELRAVGACNIAAGLTHGFPVSSSSSRTALADVV-G
MAB_4448|M.abscessus_ATCC_1997 AIAHHT-GQQIDYNRQILAEGLANLAGGFFQSLPGSGSLSRSAINYQS-G
: . * ..:. * .: . :: *
MSMEG_6453|M.smegmatis_MC2_155 AATRLSAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMISATTI
TH_2104|M.thermoresistible__bu ARTRLAAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMVSLHTA
MMAR_4750|M.marinum_M ARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWHSI
MUL_0321|M.ulcerans_Agy99 ARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWHSI
MLBr_02279|M.leprae_Br4923 AKSRASSIMHGIWILLFTIPFAGLVDQIPSAALAGLLIVVGVQLLKPAHI
MAV_0121|M.avium_104 AKTRASTIMHGFWVLVFAVPFAGLVEKIPTAALAGLLIVIGIELLKPAHI
Mflv_4975|M.gilvum_PYR-GCK ARTQMYSLVVLAVVAVVVVFGGGLVSHVPAAALGGLIVYAALKLVDVRSF
Mvan_1430|M.vanbaalenii_PYR-1 ARTQRYSLVVLVVVSVVVLFGGSVVSTIPAAALGGLIVYAAAKLVDVAGF
Mb1768c|M.bovis_AF2122/97 GRTQLYSLIALGLVVIVMVFASGLLAMFPIAALGALVVYAALRLIDLSEF
Rv1739c|M.tuberculosis_H37Rv GRTQLYSLIALGLVVIVMVFASGLLAMFPIAALGALVVYAALRLIDLSEF
MAB_4448|M.abscessus_ATCC_1997 AATRFSGIVSAATVTIALLLFAPLLRYIPQAALAGLLLVTAVRLVDFHRL
. :: :: : : .* :** .::: . :.
MSMEG_6453|M.smegmatis_MC2_155 R--KIVRSTRSDALIFVLTAVITVCFD-LIEAVEIGILVAAFFALRSVAR
TH_2104|M.thermoresistible__bu R--RILRSTRSDALTFVLTALVTITFD-LIEAVQIGVLVAAFFALRNVAR
MMAR_4750|M.marinum_M APATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRVAH
MUL_0321|M.ulcerans_Agy99 APATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRVAH
MLBr_02279|M.leprae_Br4923 ET-----ALRNGDLAVYLVTAVCVVFLNLLHGVMIGLAVAIALTGWRVIR
MAV_0121|M.avium_104 ET-----ALRNGDLAIYLVTVTSVIFLNLLHGVLIGLLLAVVVTGWRVVR
Mflv_4975|M.gilvum_PYR-GCK RA---LARFRRSEVVLAALTAIAVTVFGLLYGVVIAVALSVLDLLRRLSH
Mvan_1430|M.vanbaalenii_PYR-1 KA---LARFRRSELVLALLTTFAVAVFGVLYGVLVAIGLTVLDLLRRLSH
Mb1768c|M.bovis_AF2122/97 RR---LARFRRSELMLALATTAAVLGLGVFYGVLAAVALSILELLRRVAH
Rv1739c|M.tuberculosis_H37Rv RR---LARFRRSELMLALATTAAVLGLGVFYGVLAAVALSILELLRRVAH
MAB_4448|M.abscessus_ATCC_1997 VY---AIKASRYDAGLVIITALVGVAVNLDTAVLVGVVLSILLFVPRAAK
. . : .* .: : :
MSMEG_6453|M.smegmatis_MC2_155 RSSVVREELPGPRRP----------GDDQIALLRLDGAMFFGAAERISN-
TH_2104|M.thermoresistible__bu RSGVTREELPGEPQP----------GDERIALLRLEGSMFFGVAERMSS-
MMAR_4750|M.marinum_M FMTVERIVESDTG------------SAAETVVYRVSGELFFASSNDLVY-
MUL_0321|M.ulcerans_Agy99 FMTVERIVESDTG------------SAAETVVYRVSCELFFASSNDLVY-
MLBr_02279|M.leprae_Br4923 ----ARVEAQPVG---------------DEWHVLVAGACTFLALPRLTR-
MAV_0121|M.avium_104 ----ARIEAEPVG---------------DGWHVVIEGACTFLALPRLTG-
Mflv_4975|M.gilvum_PYR-GCK AHDSVQGLVPGLAGMHDVDDYPDARIVPGLVVYRYDAPLCFANAEDFRRR
Mvan_1430|M.vanbaalenii_PYR-1 AHDSVLGLVPGVAGMHDVDDYPDAALIPGLLVYRYDAPLCFANAEDFRRR
Mb1768c|M.bovis_AF2122/97 PHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRR
Rv1739c|M.tuberculosis_H37Rv PHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRR
MAB_4448|M.abscessus_ATCC_1997 LKAAELVVTDEGVIRERTPQ-DRPTGAGAPVIYDLEGELFFGAAPELDRY
* :
MSMEG_6453|M.smegmatis_MC2_155 AITDAEHPHVSV-----VIIRMSQLGMLDATGAHTLAEITTELESRGITV
TH_2104|M.thermoresistible__bu TISEIEADDISV-----VIIRLSQLGTLDATGANSLAQIATELERRGITV
MMAR_4750|M.marinum_M QFNYVDDPDN-------VVIDMSQSHIWDASTVAALDAIITKYHAKGRCV
MUL_0321|M.ulcerans_Agy99 QFNYVDDPDN-------VVIDMSQSHIWDASTVAALDAIITKYHAKGRCV
MLBr_02279|M.leprae_Br4923 VLASVPPCTR--------VTVNISVNYLDHAAHQAIHDWQRQHHATGGTV
MAV_0121|M.avium_104 VLASIPERTS--------VTVHLLTNYLDHAAHQAIGDWQRRHCATGGTV
Mflv_4975|M.gilvum_PYR-GCK ALEAIDQMDQPT---RWFVLNAEANVEVDMTAIEALDQVRQDCLRRGIVF
Mvan_1430|M.vanbaalenii_PYR-1 ALEAVDHMDQASPPVRWFLLNAEANVEVDMTAIEALDQLREECGRRGIVF
Mb1768c|M.bovis_AF2122/97 ALTVVDQDPGQV---EWFVLNAESNVEVDLTALDALDQLRTELLRRGIVF
Rv1739c|M.tuberculosis_H37Rv ALTVVDQDPGQV---EWFVLNAESNVEVDLTALDALDQLRTELLRRGIVF
MAB_4448|M.abscessus_ATCC_1997 LESLHTRIRDEH--LKVVILRLKRVRHPDVVCIERLEHFIREQQQLGVTV
: * : * .
MSMEG_6453|M.smegmatis_MC2_155 IIKGVRPEHMDLLANVGVFESLRHENHLLDSLDDAVAHARTHVARQPH--
TH_2104|M.thermoresistible__bu IIKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIEHARSHVARQQTAR
MMAR_4750|M.marinum_M EIIGLNQDSAERHGRLSGQFGAEH--------------------------
MUL_0321|M.ulcerans_Agy99 EIIGLNQDSAERHGRLSGQFGAEH--------------------------
MLBr_02279|M.leprae_Br4923 HINGVVETGHFSRCAMGDLIGPEQQPEAAA--------------------
MAV_0121|M.avium_104 EVRDTTEPAARRRNSHLSLVEQVSSPGGA---------------------
Mflv_4975|M.gilvum_PYR-GCK AMARVKQDLREALAAGGVLDEIGQDRLYMTLPTAVAAYQAWVASGNKG--
Mvan_1430|M.vanbaalenii_PYR-1 AMARVKQDLRDALTAAGVIDKIGEDRLYMTLPTAVEAYRAWAASRGTD--
Mb1768c|M.bovis_AF2122/97 AMARVKQDLRESLRAASLLDKIGEDHIFMTLPTAVQAFRRR---------
Rv1739c|M.tuberculosis_H37Rv AMARVKQDLRESLRAASLLDKIGEDHIFMTLPTAVQAFRRR---------
MAB_4448|M.abscessus_ATCC_1997 LLAGVRPDSLALLENVGFTHWLPPEQVFPEEEKEFSATLRAVRYAQSRLE
:
MSMEG_6453|M.smegmatis_MC2_155 -----------------
TH_2104|M.thermoresistible__bu TTS--------------
MMAR_4750|M.marinum_M -----------------
MUL_0321|M.ulcerans_Agy99 -----------------
MLBr_02279|M.leprae_Br4923 -----------------
MAV_0121|M.avium_104 -----------------
Mflv_4975|M.gilvum_PYR-GCK -----------------
Mvan_1430|M.vanbaalenii_PYR-1 -----------------
Mb1768c|M.bovis_AF2122/97 -----------------
Rv1739c|M.tuberculosis_H37Rv -----------------
MAB_4448|M.abscessus_ATCC_1997 EEPPNPAANPEKLYYLV