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MPSAPGLFESYDAIKARRDVIAGLTVAAISLPQAMAYALIAGVDPKYGVYSAIVVTAIASIFGSSSHLIN GPTSAISLLVFSSLAFLDPENRTGLFEALFLLGVLVGTIQILIAVFKLGDLTRYISESVVIGFMASAALL LAIGQLANAIGVRDKGDGHMQVLQRAWLTLFHGDAVNYRALFLSVTAVALAVLLRRLVQRYELPQIDMLL VLIVTAVIAYAYGWTVPDGTGHTDVKISGKIPASLPEFHIPEVQVSTLGELSHGALAIAFIGLIEALSIA KAIAHHTGQQIDYNRQILAEGLANLAGGFFQSLPGSGSLSRSAINYQSGAATRFSGIVSAATVTIALLLF APLLRYIPQAALAGLLLVTAVRLVDFHRLVYAIKASRYDAGLVIITALVGVAVNLDTAVLVGVVLSILLF VPRAAKLKAAELVVTDEGVIRERTPQDRPTGAGAPVIYDLEGELFFGAAPELDRYLESLHTRIRDEHLKV VILRLKRVRHPDVVCIERLEHFIREQQQLGVTVLLAGVRPDSLALLENVGFTHWLPPEQVFPEEEKEFSA TLRAVRYAQSRLEEEPPNPAANPEKLYYLV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4448 | - | - | 100% (590) | putative sulfate transporter |
| M. abscessus ATCC 19977 | MAB_3098 | - | 4e-29 | 26.27% (415) | transmembrane carbonic anhydrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1768c | - | 4e-50 | 28.68% (551) | sulphate-transport transmembrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_1119 | - | 8e-56 | 29.43% (564) | sulphate transporter |
| M. tuberculosis H37Rv | Rv1739c | - | 2e-49 | 28.68% (551) | sulphate-transport transmembrane protein ABC transporter |
| M. leprae Br4923 | MLBr_02279 | - | 3e-30 | 23.77% (547) | putative transmembrane transport protein |
| M. marinum M | MMAR_4750 | - | 1e-42 | 27.74% (465) | integral membrane transporter |
| M. avium 104 | MAV_0121 | - | 2e-31 | 24.89% (470) | carbonate dehydratase |
| M. smegmatis MC2 155 | MSMEG_6453 | - | 3e-57 | 29.85% (526) | sulfate permease |
| M. thermoresistible (build 8) | TH_2104 | - | 8e-59 | 29.14% (525) | sulfate permease |
| M. ulcerans Agy99 | MUL_0321 | - | 2e-40 | 26.99% (478) | integral membrane transporter |
| M. vanbaalenii PYR-1 | Mvan_5693 | - | 3e-55 | 29.13% (563) | sulphate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1119|M.gilvum_PYR-GCK ------MITIGR--LGRLLPQRSDYTDLRRSWRADLLAGVTVGVVALPLA
Mvan_5693|M.vanbaalenii_PYR-1 ------MIAAATRNLRRLLPSRRDYADLPRSWRRDVLAGVTVGVVALPLA
MSMEG_6453|M.smegmatis_MC2_155 --------MLAN--LARLLPHKNDYTDVPRTWRQDVLAGITVGVVALPLA
TH_2104|M.thermoresistible__bu ------VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLA
Mb1768c|M.bovis_AF2122/97 -------MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQA
Rv1739c|M.tuberculosis_H37Rv -------MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQA
MMAR_4750|M.marinum_M ---------------------MLAALRSPTRLRTEVLAGLVVALALIPEA
MUL_0321|M.ulcerans_Agy99 MSSQQVSAVPTIRKAGDPSTAVLAALRSPTRLRTEVLAGLVVALALIPEA
MLBr_02279|M.leprae_Br4923 ---------------------------MRSAIRYDLPASLVVFLVALPLS
MAV_0121|M.avium_104 -------------------MSTSRSERLREVLRYDLPASLVVFLVALPLS
MAB_4448|M.abscessus_ATCC_1997 ----------------MPSAPGLFESYDAIKARRDVIAGLTVAAISLPQA
* :: *.:.* :* :
Mflv_1119|M.gilvum_PYR-GCK LAFGISSGVGAAAGLITAVVAGLVAAVFGGS----SVQVSGPTGAMAVVL
Mvan_5693|M.vanbaalenii_PYR-1 LAFGISSGVGAAAGLITAVVAGLVAAVFGGS----AVQVSGPTGAMAVVL
MSMEG_6453|M.smegmatis_MC2_155 LAFGISSGVGAAAGLITAVVAGLVAAVFGGS----HVQVSGPTGAMAVVL
TH_2104|M.thermoresistible__bu LAFGISSGVGAAAGLITAVVAGLVAAVFGGS----HIQVSGPTGAMAVIL
Mb1768c|M.bovis_AF2122/97 MAYATVAGLPPAAGLWASIAPLAIYALLGSSRQLSIGPESATALMTAAVL
Rv1739c|M.tuberculosis_H37Rv MAYATVAGLPPAAGLWASIAPLAIYALLGSSRQLSIGPESATALMTAAVL
MMAR_4750|M.marinum_M ISFSIIAGVDPRVGLFASFTMAVTIAVVGGR----PAMISAATGAIALVI
MUL_0321|M.ulcerans_Agy99 ISFSIIAGVDPRVGLFASFTMAVTIAVVGGR----LAMISAATGAIALVI
MLBr_02279|M.leprae_Br4923 LGIAIASDTPVLAGLIAAIVGGIVAGALGGS----PLQVSGPAAGLTVVI
MAV_0121|M.avium_104 LGIAIASDAPVLAGLIAAIVGGIVGGWLGGS----PLQVSGPAAGLTVVV
MAB_4448|M.abscessus_ATCC_1997 MAYALIAGVDPKYGVYSAIVVTAIASIFGSSSHLINGPTSAISLLVFSSL
:. . :. *: ::.. . .*. *. : :
Mflv_1119|M.gilvum_PYR-GCK APIVAMHG---LGSIALVTVLAGLLVLLAGVTGLGRAVTFIPWPVIEGFT
Mvan_5693|M.vanbaalenii_PYR-1 APIVASHG---LGSIALVTLLGGLIVLLAGVTGLGRAVTFIPWPVIEGFT
MSMEG_6453|M.smegmatis_MC2_155 APIVAEHG---LGSIALVTVLAGLLVLAAGITGLGRAVTFIPWPVIEGFT
TH_2104|M.thermoresistible__bu APIVAQHG---LTSIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIEGFT
Mb1768c|M.bovis_AF2122/97 APMAAGDLRRYAVLAATLGLLVGLICLLAGTARLGFLASLLSRPVLVGYM
Rv1739c|M.tuberculosis_H37Rv APMAAGDLRRYAVLAATLGLLVGLICLLAGTARLGFLASLRSRPVLVGYM
MMAR_4750|M.marinum_M APLAREHGADYFIAAVILAGLVQITLSLLGVARL---MRFIPRSVMVGFV
MUL_0321|M.ulcerans_Agy99 APLAREQGADYFIAAVILAGLVQITLSLLGVARL---MRFIPRSVMVGFV
MLBr_02279|M.leprae_Br4923 ADLISDFG---WGVTCFITVAAGVLQVLLGLSRVARAALAISPVVVHAML
MAV_0121|M.avium_104 ADVVAEFG---WGVTCFITVVAGVLQVLLGFSRIARAALAISPVVVHAML
MAB_4448|M.abscessus_ATCC_1997 AFLDPENRTGLFEALFLLGVLVGTIQILIAVFKLGDLTRYISESVVIGFM
* : : . : . *: .
Mflv_1119|M.gilvum_PYR-GCK LGIAAIIFLQQIPAAFAAGGPPGE--RTLPAAWHVVTHADWS---EAVKS
Mvan_5693|M.vanbaalenii_PYR-1 LGIAAIIFLQQVPAAFSATSPPGQ--RTLTAAWQVVTHADWS---QAGKT
MSMEG_6453|M.smegmatis_MC2_155 LGIAAIIFLQQVPAALAQQAPSGE--RTLLAAFTVVRNADWG---EAAKT
TH_2104|M.thermoresistible__bu LGIAAIIFLQQVPAAFATEAPAGQ--RTLVAAWHVVTHADWT---AAVKT
Mb1768c|M.bovis_AF2122/97 AGIALVMISSQLGTITGTSVEGNEFFSEVHSFATSVTRVHWP---TFVLA
Rv1739c|M.tuberculosis_H37Rv AGIALVMISSQLGTITGTSVEGNEFFSEVHSFATSVTRVHWP---TFVLA
MMAR_4750|M.marinum_M NALAILIFLSQLPHLLG------------------VPPVVYP---FVIVG
MUL_0321|M.ulcerans_Agy99 NALAILIFLSQVPHLLG------------------VPAVVYP---FVIVG
MLBr_02279|M.leprae_Br4923 AGVGITIALQQAHVLLGGKSKSTA-WHNAIGLPSQILGAHRP---GVILG
MAV_0121|M.avium_104 AGIGITIALQQVHVLLGGSSKSSA-WSNVTGLPAQILGAHRP---GLVLG
MAB_4448|M.abscessus_ATCC_1997 ASAALLLAIGQLANAIGVRDKGDGHMQVLQRAWLTLFHGDAVNYRALFLS
. . : * . :
Mflv_1119|M.gilvum_PYR-GCK LGVIAFVVALMVALPRIHRAIPESLAAVVGATVAVGVLGISVATIG----
Mvan_5693|M.vanbaalenii_PYR-1 LGVIAFVAALMLLLPRIHRAIPESLAAVIAATVVVAALGISVATIG----
MSMEG_6453|M.smegmatis_MC2_155 LAVVGVVAVLMIVLPRVHSGIPASLTAVIVATVLIVALDIPVATIG----
TH_2104|M.thermoresistible__bu LSVVSLVALLMVVLPRLHRSIPESLTAVVAATVIVTVFGISVATIG----
Mb1768c|M.bovis_AF2122/97 MSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKG-IAIVG----
Rv1739c|M.tuberculosis_H37Rv MSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKG-IAIVG----
MMAR_4750|M.marinum_M LLLMVFLPKLTTVVP---APLVAIVVLTAAAVAFSVEIPN-VGDEG----
MUL_0321|M.ulcerans_Agy99 LLLMVFLPKLTTVVP---APLVAIVVLTAAAVAFSVEILN-VGDEG----
MLBr_02279|M.leprae_Br4923 VLVITILIAWR-WVPARVARIPGPLVAIVVTTLVSVVFPFHVSRIQ----
MAV_0121|M.avium_104 LLVIAILVAWR-WVPARLAIVPGPLVAIVVVTIISMVLPFKVSRIE----
MAB_4448|M.abscessus_ATCC_1997 VTAVALAVLLRRLVQRYELPQIDMLLVLIVTAVIAYAYGWTVPDGTGHTD
: : . : .. :
Mflv_1119|M.gilvum_PYR-GCK -----ELP-SHLPAPMLP--QIVPGALRDLFGAALAIAALAAIESLLSAR
Mvan_5693|M.vanbaalenii_PYR-1 -----ELP-SHLPAPVLP--HADAGALRDLFGAALAIAALAAIESLLSAR
MSMEG_6453|M.smegmatis_MC2_155 -----ELP-SHLPAPVLP--HVDVNTLRTMFSAALAIAALAAIESLLSAR
TH_2104|M.thermoresistible__bu -----ELP-SQLPTPVLP--QADMGAMQTLLGAALAIAALAAIESLLSAR
Mb1768c|M.bovis_AF2122/97 -----RIP-SGLPTPGVP--PVSVEDLRALIIPAAGIAIVTFTDGVLTAR
Rv1739c|M.tuberculosis_H37Rv -----RIP-SGLPTPGVP--PVSVEDLRALIIPAAGIAIVTFTDGVLTAR
MMAR_4750|M.marinum_M -----QLP-SSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLTAK
MUL_0321|M.ulcerans_Agy99 -----QLP-SSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLTAK
MLBr_02279|M.leprae_Br4923 -----VDNRSSLDVLQLP--KLPDGHWGAVVLGVITVALIASVESLLSAV
MAV_0121|M.avium_104 -----LDG-SVLDAVRLP--SLPHGNWGAVAIAVITVTLITSVQSLLTAV
MAB_4448|M.abscessus_ATCC_1997 VKISGKIP-ASLPEFHIP--EVQVSTLGELSHGALAIAFIGLIEALSIAK
: * :* : . :: : :.: *
Mflv_1119|M.gilvum_PYR-GCK VAATMAPTGPYDPDRELVGQGLASVASGAFGGMPATGAIARTAVNVRS-G
Mvan_5693|M.vanbaalenii_PYR-1 VAATMAPTGPYDPDRELVGQGLASVASGVFGGMPATGAIARTAVNVRS-G
MSMEG_6453|M.smegmatis_MC2_155 VAATMSPTGPYDPNRELVGQGLASVASGAFGGMPATGAIARTAVNVRS-G
TH_2104|M.thermoresistible__bu VAATMSATGPYHPDRELVGQGMASVASGLFGGMPATGAIARTAVNVRS-G
Mb1768c|M.bovis_AF2122/97 AFAARRGQ-EVNANAELRAVGACNIAAGLTHGFPVSSSSSRTALADVVGG
Rv1739c|M.tuberculosis_H37Rv AFAARRGQ-EVNANAELRAVGACNIAAGLTHGFPVSSSSSRTALADVVGG
MMAR_4750|M.marinum_M LVDDITDT-HSNKTREAWGQGVANVVTGFFGGMGGCAMIGQTMINVKVSG
MUL_0321|M.ulcerans_Agy99 LVDDITDT-HSNKTREAWGQGVANVVTGFFGGMGGCAMIGQTMINVKVPG
MLBr_02279|M.leprae_Br4923 SLDKMHNGPRTDLNRELIGQGAANIVSGAIGGLPITGVIVRSSTNVIA-G
MAV_0121|M.avium_104 SIDRMHTGPRTDFNRELIGQGAANIASGALGGLPIAGVIVRSSANVNA-G
MAB_4448|M.abscessus_ATCC_1997 AIAHHTGQ-QIDYNRQILAEGLANLAGGFFQSLPGSGSLSRSAINYQS-G
. : . * ..:. * .: . :: *
Mflv_1119|M.gilvum_PYR-GCK ARTRLAAVVHSVVLLGVVYLATGPVAAIPLAALSGVLMVTSFRMISRSTM
Mvan_5693|M.vanbaalenii_PYR-1 ARTRLSAVVHSLVLLGVVYLATGPVSAIPLAALSGVLMVTSFRMISWSTI
MSMEG_6453|M.smegmatis_MC2_155 AATRLSAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMISATTI
TH_2104|M.thermoresistible__bu ARTRLAAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMVSLHTA
Mb1768c|M.bovis_AF2122/97 RTQLYSLIALGLVVIVMVFASG-LLAMFPIAALGALVVYAALRLIDLSEF
Rv1739c|M.tuberculosis_H37Rv RTQLYSLIALGLVVIVMVFASG-LLAMFPIAALGALVVYAALRLIDLSEF
MMAR_4750|M.marinum_M ARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWHSI
MUL_0321|M.ulcerans_Agy99 ARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWHSI
MLBr_02279|M.leprae_Br4923 AKSRASSIMHGIWILLFTIPFAGLVDQIPSAALAGLLIVVGVQLLKPAHI
MAV_0121|M.avium_104 AKTRASTIMHGFWVLVFAVPFAGLVEKIPTAALAGLLIVIGIELLKPAHI
MAB_4448|M.abscessus_ATCC_1997 AATRFSGIVSAATVTIALLLFAPLLRYIPQAALAGLLLVTAVRLVDFHRL
: . . : : :* :** .::: .. :.
Mflv_1119|M.gilvum_PYR-GCK R--KILTSTRSDATTFVLTAVVTVCFD-LIEAVQIGILVAAFFALRSVAR
Mvan_5693|M.vanbaalenii_PYR-1 R--KIVTSTRSDALTFVLTAVITVCFD-LIEAVEIGILVAAFFALHSVAR
MSMEG_6453|M.smegmatis_MC2_155 R--KIVRSTRSDALIFVLTAVITVCFD-LIEAVEIGILVAAFFALRSVAR
TH_2104|M.thermoresistible__bu R--RILRSTRSDALTFVLTALVTITFD-LIEAVQIGVLVAAFFALRNVAR
Mb1768c|M.bovis_AF2122/97 R--RLARFRRSELMLALATTAAVLGLG-VFYGVLAAVALSILELLRRVAH
Rv1739c|M.tuberculosis_H37Rv R--RLARFRRSELMLALATTAAVLGLG-VFYGVLAAVALSILELLRRVAH
MMAR_4750|M.marinum_M APATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRVAH
MUL_0321|M.ulcerans_Agy99 APATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRVAH
MLBr_02279|M.leprae_Br4923 ET----ALRNGDLAVYLVTAVCVVFLN-LLHGVMIGLAVAIALTGWRVIR
MAV_0121|M.avium_104 ET----ALRNGDLAIYLVTVTSVIFLN-LLHGVLIGLLLAVVVTGWRVVR
MAB_4448|M.abscessus_ATCC_1997 VY--AIKASRYDAGLVIITALVGVAVN-LDTAVLVGVVLSILLFVPRAAK
. : : *. : : .* .: : . :
Mflv_1119|M.gilvum_PYR-GCK RSSVVREELPAPHR----------PGDEEIALLRLDGAMFFGAAERISN-
Mvan_5693|M.vanbaalenii_PYR-1 RSSVVREELPAPYQ----------PGDEEIALLRLDGAMFFGVAERISN-
MSMEG_6453|M.smegmatis_MC2_155 RSSVVREELPGPRR----------PGDDQIALLRLDGAMFFGAAERISN-
TH_2104|M.thermoresistible__bu RSGVTREELPGEPQ----------PGDERIALLRLEGSMFFGVAERMSS-
Mb1768c|M.bovis_AF2122/97 PHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRR
Rv1739c|M.tuberculosis_H37Rv PHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRR
MMAR_4750|M.marinum_M -FMTVERIVESDTG-----------SAAETVVYRVSGELFFASSNDLVYQ
MUL_0321|M.ulcerans_Agy99 -FMTVERIVESDTG-----------SAAETVVYRVSCELFFASSNDLVYQ
MLBr_02279|M.leprae_Br4923 ARVEAQPVG-------------------DEWHVLVAGACTFLALPRLTRV
MAV_0121|M.avium_104 ARIEAEPVG-------------------DGWHVVIEGACTFLALPRLTGV
MAB_4448|M.abscessus_ATCC_1997 LKAAELVVTDEGVIRERTPQ-DRPTGAGAPVIYDLEGELFFGAAPELDRY
* :
Mflv_1119|M.gilvum_PYR-GCK --AIVDGDHPR-TSVVIIRMSQLGMLDATGANTLAQICTELEARGITVII
Mvan_5693|M.vanbaalenii_PYR-1 --AIIDSDHPR-TSVVIIRMSQLGMLDATGANTLAQICTELEARGITVII
MSMEG_6453|M.smegmatis_MC2_155 --AITDAEHPH-VSVVIIRMSQLGMLDATGAHTLAEITTELESRGITVII
TH_2104|M.thermoresistible__bu --TISEIEADD-ISVVIIRLSQLGTLDATGANSLAQIATELERRGITVII
Mb1768c|M.bovis_AF2122/97 ALTVVDQDPGQ-VEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAM
Rv1739c|M.tuberculosis_H37Rv ALTVVDQDPGQ-VEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAM
MMAR_4750|M.marinum_M FNYVDDPDN------VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVEI
MUL_0321|M.ulcerans_Agy99 FNYVDDPDN------VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVEI
MLBr_02279|M.leprae_Br4923 LASVPPCTR------VTVNISVNYLDHAAHQAIHDWQRQHHATGGTVHIN
MAV_0121|M.avium_104 LASIPERTS------VTVHLLTNYLDHAAHQAIGDWQRRHCATGGTVEVR
MAB_4448|M.abscessus_ATCC_1997 LESLHTRIRDEHLKVVILRLKRVRHPDVVCIERLEHFIREQQQLGVTVLL
: . : . . *
Mflv_1119|M.gilvum_PYR-GCK KGVRPEHSALLANVGVFESLRHERHLVDTLDEAIEHARTHARRQPH----
Mvan_5693|M.vanbaalenii_PYR-1 KGVRPEHSALLSSVGVFESLRHENHLVDTLDEAIEHARTHAHRQPH----
MSMEG_6453|M.smegmatis_MC2_155 KGVRPEHMDLLANVGVFESLRHENHLLDSLDDAVAHARTHVARQPH----
TH_2104|M.thermoresistible__bu KGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIEHARSHVARQQTARTT
Mb1768c|M.bovis_AF2122/97 ARVKQDLRESLRAASLLDKIGEDHIFMTLPTAVQAFRRR-----------
Rv1739c|M.tuberculosis_H37Rv ARVKQDLRESLRAASLLDKIGEDHIFMTLPTAVQAFRRR-----------
MMAR_4750|M.marinum_M IGLNQDS--AERHGRLSGQFGAEH--------------------------
MUL_0321|M.ulcerans_Agy99 IGLNQDS--AERHGRLSGQFGAEH--------------------------
MLBr_02279|M.leprae_Br4923 GVVETGHFSRCAMGDLIGPEQQPEAAA-----------------------
MAV_0121|M.avium_104 DTTEPAARRRNSHLSLVEQVSSPGGA------------------------
MAB_4448|M.abscessus_ATCC_1997 AGVRPDSLALLENVGFTHWLPPEQVFPEEEKEFSATLRAVRYAQSRLEEE
. .
Mflv_1119|M.gilvum_PYR-GCK ---------------
Mvan_5693|M.vanbaalenii_PYR-1 ---------------
MSMEG_6453|M.smegmatis_MC2_155 ---------------
TH_2104|M.thermoresistible__bu S--------------
Mb1768c|M.bovis_AF2122/97 ---------------
Rv1739c|M.tuberculosis_H37Rv ---------------
MMAR_4750|M.marinum_M ---------------
MUL_0321|M.ulcerans_Agy99 ---------------
MLBr_02279|M.leprae_Br4923 ---------------
MAV_0121|M.avium_104 ---------------
MAB_4448|M.abscessus_ATCC_1997 PPNPAANPEKLYYLV