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LAALRSPTRLRTEVLAGLVVALALIPEAISFSIIAGVDPRVGLFASFTMAVTIAVVGGRPAMISAATGAI ALVIAPLAREHGADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMVGFVNALAILIFLSQLPHLLGVP PVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEIPNVGDEGQLPSSLPTLLVPHVPFAL ETLSIIGPYALAMALVGLLESLLTAKLVDDITDTHSNKTREAWGQGVANVVTGFFGGMGGCAMIGQTMIN VKVSGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWHSIAPATLRRMPRSETLV MLATVVVTVATHNLAYGVVAGVLTAMVLFARRVAHFMTVERIVESDTGSAAETVVYRVSGELFFASSNDL VYQFNYVDDPDNVVIDMSQSHIWDASTVAALDAIITKYHAKGRCVEIIGLNQDSAERHGRLSGQFGAEH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4750 | - | - | 100% (490) | integral membrane transporter |
| M. marinum M | MMAR_0913 | sulP | 2e-36 | 27.93% (487) | transmembrane carbonic anhydrase, SulP |
| M. marinum M | MMAR_0914 | sulP_1 | 6e-34 | 26.77% (467) | transmembrane carbonic anhydrase, SulP_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1734 | - | 4e-53 | 30.02% (473) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1119 | - | 1e-53 | 32.34% (501) | sulphate transporter |
| M. tuberculosis H37Rv | Rv1707 | - | 4e-53 | 30.02% (473) | transmembrane protein |
| M. leprae Br4923 | MLBr_02279 | - | 1e-36 | 27.22% (485) | putative transmembrane transport protein |
| M. abscessus ATCC 19977 | MAB_4448 | - | 7e-43 | 27.74% (465) | putative sulfate transporter |
| M. avium 104 | MAV_0121 | - | 2e-35 | 25.41% (492) | carbonate dehydratase |
| M. smegmatis MC2 155 | MSMEG_1448 | - | 0.0 | 77.35% (490) | integral membrane transporter |
| M. thermoresistible (build 8) | TH_2104 | - | 5e-56 | 31.04% (509) | sulfate permease |
| M. ulcerans Agy99 | MUL_0321 | - | 0.0 | 98.57% (490) | integral membrane transporter |
| M. vanbaalenii PYR-1 | Mvan_1159 | - | 0.0 | 79.18% (485) | sulphate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4750|M.marinum_M ---------------------MLAALRSPTRLRTEVLAGLVVALALIPEA
MUL_0321|M.ulcerans_Agy99 MSSQQVSAVPTIRKAGDPSTAVLAALRSPTRLRTEVLAGLVVALALIPEA
MSMEG_1448|M.smegmatis_MC2_155 ------MTSATITPREEQS--VWAALRSPRRLRTEVLAGLVVALALIPEA
Mvan_1159|M.vanbaalenii_PYR-1 ----MGTMVEAITPQQEQS--VLAALRSPRRLRTEVLGGLVVALALIPEA
Mb1734|M.bovis_AF2122/97 ---------------------------MLQRIARELLSGVAVAIVALPLA
Rv1707|M.tuberculosis_H37Rv ---------------------------MLQRIARELLSGVAVAIVALPLA
Mflv_1119|M.gilvum_PYR-GCK --------MITIGRLGRLLPQRSDYTDLRRSWRADLLAGVTVGVVALPLA
TH_2104|M.thermoresistible__bu ------VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLA
MLBr_02279|M.leprae_Br4923 ---------------------------MRSAIRYDLPASLVVFLVALPLS
MAV_0121|M.avium_104 -------------------MSTSRSERLREVLRYDLPASLVVFLVALPLS
MAB_4448|M.abscessus_ATCC_1997 ----------------MPSAPGLFESYDAIKARRDVIAGLTVAAISLPQA
:: ..:.* :* :
MMAR_4750|M.marinum_M ISFSIIAG---VDPRVGLFASFTMAVTIAVVGGRPAMISAATGAIALVIA
MUL_0321|M.ulcerans_Agy99 ISFSIIAG---VDPRVGLFASFTMAVTIAVVGGRLAMISAATGAIALVIA
MSMEG_1448|M.smegmatis_MC2_155 ISFSIIAG---VDPRVGLFASFTMAVTIAIVGGRPAMISAATGAVALVVA
Mvan_1159|M.vanbaalenii_PYR-1 ISFSIIAG---VDPRVGLFASFTMAVTIAIVGGRPAMISAATGAVALVIA
Mb1734|M.bovis_AF2122/97 IAFGITATGTSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTGPITVVAT
Rv1707|M.tuberculosis_H37Rv IAFGITATGTSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTGPITVVAT
Mflv_1119|M.gilvum_PYR-GCK LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSSVQVSGPTGAMAVVLA
TH_2104|M.thermoresistible__bu LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSHIQVSGPTGAMAVILA
MLBr_02279|M.leprae_Br4923 LGIAIASD---TPVLAGLIAAIVGGIVAGALGGSPLQVSGPAAGLTVVIA
MAV_0121|M.avium_104 LGIAIASD---APVLAGLIAAIVGGIVGGWLGGSPLQVSGPAAGLTVVVA
MAB_4448|M.abscessus_ATCC_1997 MAYALIAG---VDPKYGVYSAIVVTAIASIFGSSSHLINGPTSAISLLVF
:. .: : *: :. . .*. :...:. ::::
MMAR_4750|M.marinum_M PLAREHG-------ADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMV
MUL_0321|M.ulcerans_Agy99 PLAREQG-------ADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMV
MSMEG_1448|M.smegmatis_MC2_155 PLVRSHG-------LDYLIATVILAGLLQLVLGGLGVARLMRFVPRSVMV
Mvan_1159|M.vanbaalenii_PYR-1 PLAHSHG-------LDYLIAAVILAGVLQLLLGGLGVAKLMRFVPRSVMV
Mb1734|M.bovis_AF2122/97 ATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRYVPHPVIS
Rv1707|M.tuberculosis_H37Rv ATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRYVPHPVIS
Mflv_1119|M.gilvum_PYR-GCK PIVAMHG-------LGSIALVTVLAGLLVLLAGVTGLGRAVTFIPWPVIE
TH_2104|M.thermoresistible__bu PIVAQHG-------LTSIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIE
MLBr_02279|M.leprae_Br4923 DLISDFG-------WGVTCFITVAAGVLQVLLGLSRVARAALAISPVVVH
MAV_0121|M.avium_104 DVVAEFG-------WGVTCFITVVAGVLQVLLGFSRIARAALAISPVVVH
MAB_4448|M.abscessus_ATCC_1997 SSLAFLDPENRTGLFEALFLLGVLVGTIQILIAVFKLGDLTRYISESVVI
. : .* . : . :. :. *:
MMAR_4750|M.marinum_M GFVNALAILIFLSQLPHLLGVP----------------------------
MUL_0321|M.ulcerans_Agy99 GFVNALAILIFLSQVPHLLGVP----------------------------
MSMEG_1448|M.smegmatis_MC2_155 GFVNALAILIFLAQIPHLLGVP----------------------------
Mvan_1159|M.vanbaalenii_PYR-1 GFVNALAILIFMSQVPHLLGVP----------------------------
Mb1734|M.bovis_AF2122/97 GFMGGIAILIIMTQLDQVRSS-------SLLVLVTVVLLLA-----SGRF
Rv1707|M.tuberculosis_H37Rv GFMGGIAILIIMTQLDQVRSS-------SLLVLVTVVLLLA-----SGRF
Mflv_1119|M.gilvum_PYR-GCK GFTLGIAAIIFLQQIPAAFAAGGPPGERTLPAAWHVVTHAD-----WSEA
TH_2104|M.thermoresistible__bu GFTLGIAAIIFLQQVPAAFATEAPAGQRTLVAAWHVVTHAD-----WTAA
MLBr_02279|M.leprae_Br4923 AMLAGVGITIALQQAHVLLGGKSKSTAWHNAIGLPSQILGA-----HRPG
MAV_0121|M.avium_104 AMLAGIGITIALQQVHVLLGGSSKSSAWSNVTGLPAQILGA-----HRPG
MAB_4448|M.abscessus_ATCC_1997 GFMASAALLLAIGQLANAIGVRDKGDGHMQVLQRAWLTLFHGDAVNYRAL
.: . . : : * .
MMAR_4750|M.marinum_M PVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEIP----
MUL_0321|M.ulcerans_Agy99 AVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEIL----
MSMEG_1448|M.smegmatis_MC2_155 WLVYPMVAVALVIIVALPKLTAAVPGPLVAIVLLTAATIGFGWSVP----
Mvan_1159|M.vanbaalenii_PYR-1 WLVYPMVAVGILVIVALPKLTAAIPGPLVAIVLLTAAAIGFGWSVP----
Mb1734|M.bovis_AF2122/97 IKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVS------INRTVD----
Rv1707|M.tuberculosis_H37Rv IKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVS------INRTVD----
Mflv_1119|M.gilvum_PYR-GCK VKSLGVIAFVVALMVALPRIHRAIPESLAAVVGATVAVGVLGISVA----
TH_2104|M.thermoresistible__bu VKTLSVVSLVALLMVVLPRLHRSIPESLTAVVAATVIVTVFGISVA----
MLBr_02279|M.leprae_Br4923 VILGVLVITILIAWRWVPARVARIPGPLVAIVVTTLVSVVFPFHVS----
MAV_0121|M.avium_104 LVLGLLVIAILVAWRWVPARLAIVPGPLVAIVVVTIISMVLPFKVS----
MAB_4448|M.abscessus_ATCC_1997 FLSVTAVALAVLLRRLVQRYELPQIDMLLVLIVTAVIAYAYGWTVPDGTG
: * . :
MMAR_4750|M.marinum_M --NVGDEGQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLT
MUL_0321|M.ulcerans_Agy99 --NVGDEGQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLT
MSMEG_1448|M.smegmatis_MC2_155 --DVADEGRLPSSLPSLLIPNVPLNLDTLKIIAPYALTMAVVGLLESLMT
Mvan_1159|M.vanbaalenii_PYR-1 --DVGDEGQLPSSLPSLLIPDVPLTFDTLRIIAPYALAMALVGLLESLMT
Mb1734|M.bovis_AF2122/97 --YIG---EIPQAMPSFDFPQVAN--STMLQVLLSAVAIALLGSLDSLLT
Rv1707|M.tuberculosis_H37Rv --YIG---EIPQAMPSFDFPQVAN--STMLQVLLSAVAIALLGSLDSLLT
Mflv_1119|M.gilvum_PYR-GCK --TIG---ELPSHLPAPMLPQIVP--GALRDLFGAALAIAALAAIESLLS
TH_2104|M.thermoresistible__bu --TIG---ELPSQLPTPVLPQADM--GAMQTLLGAALAIAALAAIESLLS
MLBr_02279|M.leprae_Br4923 --RIQ--VDNRSSLDVLQLPKLPD--GHWGAVVLGVITVALIASVESLLS
MAV_0121|M.avium_104 --RIE--LDG-SVLDAVRLPSLPH--GNWGAVAIAVITVTLITSVQSLLT
MAB_4448|M.abscessus_ATCC_1997 HTDVKISGKIPASLPEFHIPEVQVS--TLGELSHGALAIAFIGLIEALSI
: : .* : .:::: : :::*
MMAR_4750|M.marinum_M AKLVDDITDTHSNKTR-EAWGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MUL_0321|M.ulcerans_Agy99 AKLVDDITDTHSNKTR-EAWGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MSMEG_1448|M.smegmatis_MC2_155 AKLVDDITDTHSNKSR-EALGQGAANIVTGFFGGMGGCAMIGQTMINVKA
Mvan_1159|M.vanbaalenii_PYR-1 AKLVDDITDTHSDKSR-EAVGQGVANVVTGFFGGMGGCAMIGQTMINVKV
Mb1734|M.bovis_AF2122/97 SLVMDNIRGTR-HRSNKELIGQGIGNIAAGLFGGLAGAGATVRSVVNVRN
Rv1707|M.tuberculosis_H37Rv SLVMDNIRGTR-HRSNKELIGQGIGNIAAGLFGGLSGAGATVRSVVNVRN
Mflv_1119|M.gilvum_PYR-GCK ARVAATMAPTGPYDPDRELVGQGLASVASGAFGGMPATGAIARTAVNVRS
TH_2104|M.thermoresistible__bu ARVAATMSATGPYHPDRELVGQGMASVASGLFGGMPATGAIARTAVNVRS
MLBr_02279|M.leprae_Br4923 AVSLDKMHNGPRTDLNRELIGQGAANIVSGAIGGLPITGVIVRSSTNVIA
MAV_0121|M.avium_104 AVSIDRMHTGPRTDFNRELIGQGAANIASGALGGLPIAGVIVRSSANVNA
MAB_4448|M.abscessus_ATCC_1997 AKAIAHHTGQQIDYNR-QILAEGLANLAGGFFQSLPGSGSLSRSAINYQS
: : .:* ..:. * : .: . :: *
MMAR_4750|M.marinum_M SGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWH
MUL_0321|M.ulcerans_Agy99 PGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWH
MSMEG_1448|M.smegmatis_MC2_155 CGARTRISTFSAGAFLLGLVVGLGDIVGRIPMAALVAVMVMVSVGTFDWH
Mvan_1159|M.vanbaalenii_PYR-1 SGARTRISTFLAGAFLLGLVVGLGDLVAQIPMAALVAVMIMVSVATLDWH
Mb1734|M.bovis_AF2122/97 -GGQTALSAATHSVVLFVFVAGLGAVVQYIPLAVLSGILILVAVGMFDWH
Rv1707|M.tuberculosis_H37Rv -GGQTALSAATHSVVLFVFVAGLGAVVQYIPLAVLSGILILVAVGMFDWH
Mflv_1119|M.gilvum_PYR-GCK -GARTRLAAVVHSVVLLGVVYLATGPVAAIPLAALSGVLMVTSFRMISRS
TH_2104|M.thermoresistible__bu -GARTRLAAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMVSLH
MLBr_02279|M.leprae_Br4923 -GAKSRASSIMHGIWILLFTIPFAGLVDQIPSAALAGLLIVVGVQLLKPA
MAV_0121|M.avium_104 -GAKTRASTIMHGFWVLVFAVPFAGLVEKIPTAALAGLLIVIGIELLKPA
MAB_4448|M.abscessus_ATCC_1997 -GAATRFSGIVSAATVTIALLLFAPLLRYIPQAALAGLLLVTAVRLVDFH
*. : : . : : ** :.* .:::: .. ..
MMAR_4750|M.marinum_M SIAPATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRV
MUL_0321|M.ulcerans_Agy99 SIAPATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRV
MSMEG_1448|M.smegmatis_MC2_155 SINPKTLRRMPKSETTVMLATVAVTVATGNLAYGVAVGTLTAMVLFARRV
Mvan_1159|M.vanbaalenii_PYR-1 SINPKTLRRMPKSETLVMVSTVAVTVATHNLAYGVAVGTLAAMVLFARRV
Mb1734|M.bovis_AF2122/97 AMR--KAHVSPRGDVIVMFTTMIITVVVD-LTIAVMVGIALSLLVHRLRS
Rv1707|M.tuberculosis_H37Rv AMR--KAHVSPRGDVIVMFTTMIITVVVD-LTIAVMVGIALSLLVHRLRS
Mflv_1119|M.gilvum_PYR-GCK TMR--KILTSTRSDATTFVLTAVVTVCFD-LIEAVQIGILVAAFFALRSV
TH_2104|M.thermoresistible__bu TAR--RILRSTRSDALTFVLTALVTITFD-LIEAVQIGVLVAAFFALRNV
MLBr_02279|M.leprae_Br4923 HIET-----ALRNGDLAVYLVTAVCVVFLNLLHGVMIGLAVAIALTGWRV
MAV_0121|M.avium_104 HIET-----ALRNGDLAIYLVTVTSVIFLNLLHGVLIGLLLAVVVTGWRV
MAB_4448|M.abscessus_ATCC_1997 RLVY--AIKASRYDAGLVIITALVGVAVN-LDTAVLVGVVLSILLFVPRA
: . . : * .* * : .
MMAR_4750|M.marinum_M AHFMTVERIVESDTG-----------SAAETVVYRVSGELFFASSNDLVY
MUL_0321|M.ulcerans_Agy99 AHFMTVERIVESDTG-----------SAAETVVYRVSCELFFASSNDLVY
MSMEG_1448|M.smegmatis_MC2_155 AHLTEVTTVGQPDP---------------DTRVYAVRGELFFASSNDLVY
Mvan_1159|M.vanbaalenii_PYR-1 AHFTEVVPVDSGAA---------------DTRVYVVTGELFFASSNDMVY
Mb1734|M.bovis_AF2122/97 RQRKAKVTQDDTG-------------------TYRIDGPLSFLSVDGVFG
Rv1707|M.tuberculosis_H37Rv RQRKAKVTQDDTG-------------------TYRIDGPLSFLSVDGVFG
Mflv_1119|M.gilvum_PYR-GCK ARRSSVVREELPAPHR---------PGDEEIALLRLDGAMFFGAAERISN
TH_2104|M.thermoresistible__bu ARRSGVTREELPGEPQ---------PGDERIALLRLEGSMFFGVAERMSS
MLBr_02279|M.leprae_Br4923 IRARVEAQPVGDEWH------------------VLVAGACTFLALPRLTR
MAV_0121|M.avium_104 VRARIEAEPVGDGWH------------------VVIEGACTFLALPRLTG
MAB_4448|M.abscessus_ATCC_1997 AKLKAAELVVTDEGVIRERTPQDRPTGAGAPVIYDLEGELFFGAAPELDR
: : * :
MMAR_4750|M.marinum_M QFN----YVDDPDN--VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVE
MUL_0321|M.ulcerans_Agy99 QFN----YVDDPDN--VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVE
MSMEG_1448|M.smegmatis_MC2_155 QFD----YVGDPDN--IVIDMSQAHIWDASTVATLDAITTKYAAKGKTVR
Mvan_1159|M.vanbaalenii_PYR-1 QFD----YAGDPDN--IVIDMSAAHIWDASTVATLDAVTTKYAAKGKTVT
Mb1734|M.bovis_AF2122/97 SLR----DGRED----VSLDLQHVTYLDTSGAQALLYFIDHSEKDGVAVS
Rv1707|M.tuberculosis_H37Rv SLR----DGRED----VSLDLQHVTYLDTSGARALLYFIDHSEKDGVAVS
Mflv_1119|M.gilvum_PYR-GCK AIV----DGDHPRTSVVIIRMSQLGMLDATGANTLAQICTELEARGITVI
TH_2104|M.thermoresistible__bu TIS----EIEADDISVVIIRLSQLGTLDATGANSLAQIATELERRGITVI
MLBr_02279|M.leprae_Br4923 VLA----SVPPCTR---VTVNISVNYLDHAAHQAIHDWQRQHHATGGTVH
MAV_0121|M.avium_104 VLA----SIPERTS---VTVHLLTNYLDHAAHQAIGDWQRRHCATGGTVE
MAB_4448|M.abscessus_ATCC_1997 YLESLHTRIRDEHLKVVILRLKRVRHPDVVCIERLEHFIREQQQLGVTVL
: * : . * *
MMAR_4750|M.marinum_M IIGLNQDSAERHGRLSGQFGAEH---------------------------
MUL_0321|M.ulcerans_Agy99 IIGLNQDSAERHGRLSGQFGAEH---------------------------
MSMEG_1448|M.smegmatis_MC2_155 IIGMNDNSAQRHARLSGQLTGAH---------------------------
Mvan_1159|M.vanbaalenii_PYR-1 IVGMNDSSAQRHAQLSGQLTGG----------------------------
Mb1734|M.bovis_AF2122/97 IKRIPPRLESQLTALADNEQRDKLRTVLESA-------------------
Rv1707|M.tuberculosis_H37Rv IKRIPPRLESQLTALADNEQRDKLRTVLESA-------------------
Mflv_1119|M.gilvum_PYR-GCK IKGVRPEHSALLANVGVFESLRHERHLVDTLDEAIEHARTHARRQPH---
TH_2104|M.thermoresistible__bu IKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIEHARSHVARQQTART
MLBr_02279|M.leprae_Br4923 INGVVETGHFSRCAMGDLIGPEQQPEAAA---------------------
MAV_0121|M.avium_104 VRDTTEPAARRRNSHLSLVEQVSSPGGA----------------------
MAB_4448|M.abscessus_ATCC_1997 LAGVRPDSLALLENVGFTHWLPPEQVFPEEEKEFSATLRAVRYAQSRLEE
:
MMAR_4750|M.marinum_M ----------------
MUL_0321|M.ulcerans_Agy99 ----------------
MSMEG_1448|M.smegmatis_MC2_155 ----------------
Mvan_1159|M.vanbaalenii_PYR-1 ----------------
Mb1734|M.bovis_AF2122/97 ----------------
Rv1707|M.tuberculosis_H37Rv ----------------
Mflv_1119|M.gilvum_PYR-GCK ----------------
TH_2104|M.thermoresistible__bu TS--------------
MLBr_02279|M.leprae_Br4923 ----------------
MAV_0121|M.avium_104 ----------------
MAB_4448|M.abscessus_ATCC_1997 EPPNPAANPEKLYYLV