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WLAELGYRVTLLESNGSLGGRTIGLTSGHGDAIENGQHVFAGSYENIFRYLDSIGTRHLLEFPDQFGVRY PGGHAEKFGLRLANLRRMMLGRVRGLGLPTLLRASPAWARLMRDVIRFDDSLDDITVDEWFDRVGFPPEV RRVVLNSMVIGLLNEQPHLASAHAFAALLRTGADRVRSFGGSAVRIGYPTVDLDTLYLDGARRVMAERGV DVRLRTRAVTVTTDAGRATGVTLSDGATVAADAVVLAVPSWNLRSLLDDVPSSEDARLSAKKLEPIPIMN AYVLLDRPLGTVAPWESLLDSDIGWVFDRDRMHGPRDDGNHLYALTTCAAYDLMPLKNSEVADRLVRALR DSYPAAADAEVLDVTVVPWPRATFSSRVGMSTIRPQNRTALPNLALAGDWTHNDWPTTMEGAAQSASHAV DLVHAELGGSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4516 | - | - | 100% (432) | amine oxidase |
| M. gilvum PYR-GCK | Mflv_1844 | - | 2e-08 | 25.75% (466) | amine oxidase |
| M. gilvum PYR-GCK | Mflv_4501 | - | 4e-06 | 24.05% (316) | amine oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1900c | - | 8e-07 | 52.38% (42) | reductase |
| M. tuberculosis H37Rv | Rv1869c | - | 8e-07 | 52.38% (42) | reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3890 | - | 1e-06 | 24.40% (455) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2344 | - | 2e-13 | 26.33% (471) | dehydrogenase |
| M. thermoresistible (build 8) | TH_1483 | - | 6e-13 | 26.19% (462) | dehydrogenase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3890|M.avium_104 MTAGATDRRRRILPAPTGLPDAGALPSRPRVAVVGGGIAGLTAATGLAER
MSMEG_2344|M.smegmatis_MC2_155 --------MQRTHTAPRGLPHAGELPRRPRVVVVGAGIAGLAAATGMAER
TH_1483|M.thermoresistible__bu ----LTDPRRVHHHAPPGLPDARGLARRPHVVVVGAGIAGLAAATGLAER
Mb1900c|M.bovis_AF2122/97 ------------------------MASSTTFVIVGGGLAGAKAVEALRRS
Rv1869c|M.tuberculosis_H37Rv ------------------------MASSTTFVIVGGGLAGAKAVEALRRS
Mflv_4516|M.gilvum_PYR-GCK ----------------------------MWLAELGYRVTLLESNG-----
.. :* :: :
MAV_3890|M.avium_104 GVAVEVIEREHYLGGRVGGWTEHHDG---TDLAMNRGFHAFFRQYYNLRA
MSMEG_2344|M.smegmatis_MC2_155 GVEVTVIERENYLGGRVGGWSEQHDG---AEYAMNRGFHAFFRQYYNLRA
TH_1483|M.thermoresistible__bu GVTVDVVEQAGYLGGRVGGWTEDIGPDVPGGAAMNRGFHAFFRQYYNLRT
Mb1900c|M.bovis_AF2122/97 -----------DFGGRIILFGD--------EEHLPYDRPPLSKEFLAGKK
Rv1869c|M.tuberculosis_H37Rv -----------DFGGRIILFGD--------EEHLPYDRPPLSKEFLAGKK
Mflv_4516|M.gilvum_PYR-GCK -----------SLGGRTIGLTSG------HGDAIENGQHVFAGSYENIFR
:*** . : . : .:
MAV_3890|M.avium_104 LLARLDPRLRMLVPVNDYPLIDAAGRRDSFRGLPRTPPLNAMAFAVRSPT
MSMEG_2344|M.smegmatis_MC2_155 LLARVDPQLRMLTPVEDYPLIDGEGRRESFRRLPHTPPWNALWFALRSPT
TH_1483|M.thermoresistible__bu LLRRIDPGLGMLTPVDDYPLVDAHGRRDTFRGLPKTPPFNAMAFALRSPT
Mb1900c|M.bovis_AF2122/97 SLSDFTIQTSDWYRDHDVDVRLGVRVSSLDRSAHTVELPDGAAVRYDKLL
Rv1869c|M.tuberculosis_H37Rv SLSDFTIQTSDWYRDHDVDVRLGVRVSSLDRSAHTVELPDGAAVRYDKLL
Mflv_4516|M.gilvum_PYR-GCK YLDSIGTRHLLEFP-DQFGVRYPGGHAEKFG-LRLANLRRMMLGRVRG--
* . .: : . .
MAV_3890|M.avium_104 FRLRDFARIDARAAAPLAAVSVPGTYRRLDHIDAATFLEDIRFPEAARHL
MSMEG_2344|M.smegmatis_MC2_155 FRLRDLMRLDAKAAAPLAAVSVPGIYDRLDHIDAETFLKDINFPPAARHL
TH_1483|M.thermoresistible__bu FRLRDLIRLNARAAAPLAAVELPGIYRHLDDTDAESFLRAINFPPAARHL
Mb1900c|M.bovis_AF2122/97 LATGSAPRRPPIPGSDAAGVHYLRSYNDAVALNSVLVQGSSLAVVGAGWI
Rv1869c|M.tuberculosis_H37Rv LATGSAPRRPPIPGSDAAGVHYLRSYNDAVALNSVLVQGSSLAVVGAGWI
Mflv_4516|M.gilvum_PYR-GCK LGLPTLLR--ASPAWARLMRDVIRFDDSLDDITVDEWFDRVGFPPEVRRV
: * . .. . :
MAV_3890|M.avium_104 AFEVFSRSFFADPAKLSAAELATMFHIYFLG-----SAEGLIFDVPSANY
MSMEG_2344|M.smegmatis_MC2_155 AFEVFSRSFFADPSNLSAAELATMFHIYFLG-----SSEGLVFDVPTSNY
TH_1483|M.thermoresistible__bu AFEVFSRSFFAQPSQLSAAELATMFHIYFLG-----SSEGLVFDVVNANF
Mb1900c|M.bovis_AF2122/97 GLEVAASARQRG-VDVTVVETAIQPLLAALG-----EAVGKVFADLHRDQ
Rv1869c|M.tuberculosis_H37Rv GLEVAASARQRG-VDVTVVETAIQPLLAALG-----EAVGKVFADLHRDQ
Mflv_4516|M.gilvum_PYR-GCK VLNSMVIGLLNEQPHLASAHAFAALLRTGADRVRSFGGSAVRIGYPTVDL
:: . .:: .. . . . : :
MAV_3890|M.avium_104 DSALWQPLRSYLEQRHVRFRLGTSVGSID----AANRFAVHTDTDEELEV
MSMEG_2344|M.smegmatis_MC2_155 DTALWEPLRRYLHEHGVRFHLGASVTRIDPVTTSPDAFAVHTDSGERLDA
TH_1483|M.thermoresistible__bu DVALWNPLRDQLESRGVRFHTGVGVRAVD----AGARFRVSCDSGDELTA
Mb1900c|M.bovis_AF2122/97 GVDLR--LQTQLEEITAADGKATGLKMRD---------------GSTVAA
Rv1869c|M.tuberculosis_H37Rv GVDLR--LQTQLEEITAADGKATGLKMRD---------------GSTVAA
Mflv_4516|M.gilvum_PYR-GCK DTLYLDGARRVMAERGVDVRLRTRAVTVT--TDAGRATGVTLSDGATVAA
. : : . . . . : .
MAV_3890|M.avium_104 DAVVLATDVAGLQRIVAASRGLANGEWRDRIAGLRTAPPFAVHRFWLDRP
MSMEG_2344|M.smegmatis_MC2_155 DAVVLAADIAGLQRIVASSPGLGDDRWRARVQGLRTAPPFAVHRLWLDRP
TH_1483|M.thermoresistible__bu DGVVLATDVTGLQRIVAASPGLGDAGWRDRIAGLHTAPPFVVHRLWLDRP
Mb1900c|M.bovis_AF2122/97 DAVLVAVGAKPNVELAQQAGLAMGEGGVLVDASLRTSDP----DIYAVGD
Rv1869c|M.tuberculosis_H37Rv DAVLVAVGAKPNVELAQQAGLAMGEGGVLVDASLRTSDP----DIYAVGD
Mflv_4516|M.gilvum_PYR-GCK DAVVLAVPSWNLRSLLDDVPSSEDAR---LSAKKLEPIPIMNAYVLLDRP
*.*::*. : . . * .
MAV_3890|M.avium_104 VSPRRPAFLGTAGHKPLDNISVLDRYEREARAWAGAHHGSVVELHSYALD
MSMEG_2344|M.smegmatis_MC2_155 VTADRPAFMGTAGHKPLDNISVLERYERQSAQWARDNGGSAVELHAYALD
TH_1483|M.thermoresistible__bu VAPDRPPFLGTGGWSPLDNVSVLETYEHQARDWARCTGGSVVELHSYAVT
Mb1900c|M.bovis_AF2122/97 IAAAEHPLLGTR---------------VRTEHWANALKQPAVAAAGMLGR
Rv1869c|M.tuberculosis_H37Rv IAAAEHPLLGTR---------------VRTEHWANALKQPAVAAAGMLGR
Mflv_4516|M.gilvum_PYR-GCK LGTVAP-------WESLLDSDIGWVFDRDRMHGPRDDGNHLYALTTCAAY
: . .
MAV_3890|M.avium_104 SAP----SGA--AALRELRRIYPETAAAQIVHETLLHRSDCPLFA-PGGY
MSMEG_2344|M.smegmatis_MC2_155 TAE----SGP--GALAQLHRLYPETATAEPVFERVLVRDDCPLFA-PGSH
TH_1483|M.thermoresistible__bu EPT----DGLRDALLDRLHALYPETADAGIVAERVLCRQDCPRFA-PGDH
Mb1900c|M.bovis_AF2122/97 PGE----YAELPYLFTDQYDLGMEYVGHAPSCDRVVFR---------GNV
Rv1869c|M.tuberculosis_H37Rv PGE----YAELPYLFTDQYDLGMEYVGHAPSCDRVVFR---------GNV
Mflv_4516|M.gilvum_PYR-GCK DLMPLKNSEVADRLVRALRDSYPAAADAEVLDVTVVPWPRATFSSRVGMS
. . :: *
MAV_3890|M.avium_104 PHRPTVVTPTPGLLLASDTVRIDLPVALMERAATTGWSAANHLLKRWGLA
MSMEG_2344|M.smegmatis_MC2_155 ADRPGVVTGVPGLVLAGDGIRLDLPAALMERAATTGWAAANVLLNRWGVA
TH_1483|M.thermoresistible__bu AGRPGVAGPHPALALAGDGIRIDLPVALMERAATTGWSAANRLLTHFGLA
Mb1900c|M.bovis_AF2122/97 AGR-----EFLSFWLDGD-------SRVLAGMNVNVWDVVDDVKG-LIRS
Rv1869c|M.tuberculosis_H37Rv AGR-----EFLSFWLDGD-------SRVLAGMNVNVWDVVDDVKG-LIRS
Mflv_4516|M.gilvum_PYR-GCK TIRPQNRTALPNLALAGDWTHNDWPTTMEG-AAQSASHAVDLVHAELGGS
. * : * .* : . ..: : :
MAV_3890|M.avium_104 GHPLVTVPTEGRSRLLRWLANREGATRS
MSMEG_2344|M.smegmatis_MC2_155 GHALRSVPTAGRFAPLRWLATREERRAS
TH_1483|M.thermoresistible__bu GHPLYTVPTRGRSAALRRLARREVRQVR
Mb1900c|M.bovis_AF2122/97 GNPVDVDRLVDPQWPLADLTTN------
Rv1869c|M.tuberculosis_H37Rv GNPVDVDRLVDPQWPLADLTTN------
Mflv_4516|M.gilvum_PYR-GCK G---------------------------
*