For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RLLDRIRGPWARRLGIATLAALLLPGVVGLTGGSVTAGAFSRPGLPVEYLMVPSPSMGRDIKVQFQSGGP NSPALYLLDGLRAQDDFNGWDINTQAFEWYLDSGISVVMPVGGQSSFYSNWYKPACGKNGCLTYNWETFL TQELPAWLQANRDVRPTNNAAVGLSMAGGSSLVLAAHHPGQFSYAGSMSGFLNPSEGWWPGLINISMGDA GGYKANDMWGPAETDPAWQYNDPMVQIPNLVANNSRIWVYCGNGTPNELGGGDLPATFLEGLTIRTNRTF QDNYLAAGGKNGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4459 | - | - | 100% (325) | putative esterase |
| M. gilvum PYR-GCK | Mflv_1164 | - | e-143 | 72.70% (326) | putative esterase |
| M. gilvum PYR-GCK | Mflv_3335 | - | e-128 | 67.09% (313) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1918c | fbpB | 1e-140 | 72.52% (313) | secreted antigen 85-B fbpB (85B) (antigen 85 complex B) |
| M. tuberculosis H37Rv | Rv1886c | fbpB | 1e-140 | 72.52% (313) | secreted antigen 85-B fbpB (85B) (antigen 85 complex B) |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | 1e-131 | 66.15% (325) | secreted antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_1579 | - | 1e-107 | 56.40% (328) | antigen 85-B precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-137 | 69.21% (328) | secreted antigen 85-C FbpC |
| M. avium 104 | MAV_5183 | - | 1e-135 | 69.57% (322) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_2078 | - | 1e-163 | 82.61% (322) | antigen 85-C |
| M. thermoresistible (build 8) | TH_2078 | fbpA | 1e-134 | 68.18% (330) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-137 | 69.21% (328) | secreted antigen 85-C FbpC |
| M. vanbaalenii PYR-1 | Mvan_1902 | - | 0.0 | 95.06% (324) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1918c|M.bovis_AF2122/97 MTDVSRKIR-------AWGRRLMIGTAAAVVLPGLVGLAGGAATAGAFSR
Rv1886c|M.tuberculosis_H37Rv MTDVSRKIR-------AWGRRLMIGTAAAVVLPGLVGLAGGAATAGAFSR
Mflv_4459|M.gilvum_PYR-GCK -MRLLDRIR------GPWARRLGIATLAALLLPGVVGLTGGSVTAGAFSR
Mvan_1902|M.vanbaalenii_PYR-1 -MRLLDRIR------GPWARRLGIAALAAVLLPGVVGLTGGSATAGAFSR
MSMEG_2078|M.smegmatis_MC2_155 -MTFIDKIR------GHWARRMTVAAVAALLLPGLVGVVGGSATAGAFSR
MLBr_02655|M.leprae_Br4923 -MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGDTAIAVAFSK
MAV_5183|M.avium_104 -MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGGSPVAGAFSK
MMAR_0328|M.marinum_M -MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSR
MUL_4793|M.ulcerans_Agy99 -MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSR
TH_2078|M.thermoresistible__bu -MKLVAKLR---GAARALPRRLTVAALAAALLPGLVGAFGGSATAGAFSR
MAB_1579|M.abscessus_ATCC_1997 -MEFLQKMR------GATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSR
. ::* :.. .: :*.*: *.: * ***:
Mb1918c|M.bovis_AF2122/97 PGLPVEYLQVPSPSMGRDIKVQFQSGGNNSPAVYLLDGLRAQDDYNGWDI
Rv1886c|M.tuberculosis_H37Rv PGLPVEYLQVPSPSMGRDIKVQFQSGGNNSPAVYLLDGLRAQDDYNGWDI
Mflv_4459|M.gilvum_PYR-GCK PGLPVEYLMVPSPSMGRDIKVQFQSGGPNSPALYLLDGLRAQDDFNGWDI
Mvan_1902|M.vanbaalenii_PYR-1 PGLPVEYLMVPSPSMGRDIKIQFQSGGPNSPALYLLDGLRAQDDFNGWDI
MSMEG_2078|M.smegmatis_MC2_155 PGLPVEYLMVPSPSMGRDIKVQFQSGGPGSHAVYLLDGLRAQDDFNGWDI
MLBr_02655|M.leprae_Br4923 PGLPVEYLQVPSPSMGHDIKIQFQGGG--QHAVYLLDGLRAQEDYNGWDI
MAV_5183|M.avium_104 PGLPVEYLEVPSPSMGRNIKVQFQGGG--PHAVYLLDGLRAQDDYNGWDI
MMAR_0328|M.marinum_M PGLPVEYLQIPSAAMGRDIKVQFQGGG--AHSVYLLDGLRAQDDYNGWDI
MUL_4793|M.ulcerans_Agy99 PGLPVEYLQIPSAAMGRDIKVQFQGGG--AHSVYLLDGLRAQDDYNGWDI
TH_2078|M.thermoresistible__bu PGLPVEYLMVPSAAMGRDIKVQFQSGGEGSPGVYLLDGLRARDDFNGWDI
MAB_1579|M.abscessus_ATCC_1997 PGLPVEYLQVPSPAMGRDIVVEFQPGG--PHAVYLLDGQRAREDYNGWDI
******** :**.:**::* ::** ** .:***** **::*:*****
Mb1918c|M.bovis_AF2122/97 NTPAFEWYYQSGLSIVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTS
Rv1886c|M.tuberculosis_H37Rv NTPAFEWYYQSGLSIVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTS
Mflv_4459|M.gilvum_PYR-GCK NTQAFEWYLDSGISVVMPVGGQSSFYSNWYKPACGKNGCLTYNWETFLTQ
Mvan_1902|M.vanbaalenii_PYR-1 NTQAFEWYLDSGISVIMPVGGQSSFYSNWYKPACGKSGCLTYNWETFLTQ
MSMEG_2078|M.smegmatis_MC2_155 NTNAFEMFLDSGLSVVMPVGGQSSFYSDWYQPACGNNGCVTYKWETFLTS
MLBr_02655|M.leprae_Br4923 NTPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYKWETFLTQ
MAV_5183|M.avium_104 NTPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYKWETFLTQ
MMAR_0328|M.marinum_M NTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTR
MUL_4793|M.ulcerans_Agy99 NTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTR
TH_2078|M.thermoresistible__bu ETAAFEWYYESGLSVIMPVGGQSSFYSDWYSPACGNNGCQTYKWETFLTQ
MAB_1579|M.abscessus_ATCC_1997 ETTAFEDYYQSGISVVMPVGGQSSNYTDWYNPAKGKDGVWTYKWETFLTT
:* *** : .**:*::******** *::**.*: *: **:******
Mb1918c|M.bovis_AF2122/97 ELPQWLSANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSALL
Rv1886c|M.tuberculosis_H37Rv ELPQWLSANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSALL
Mflv_4459|M.gilvum_PYR-GCK ELPAWLQANRDVRPTNNAAVGLSMAGGSSLVLAAHHPGQFSYAGSMSGFL
Mvan_1902|M.vanbaalenii_PYR-1 ELPGWLQANRDVKPTGSAAVGLSMAGGSSLVLAAHHPGQFVWAGSMSGFL
MSMEG_2078|M.smegmatis_MC2_155 ELPEWLAANRDVAATGNAAIGLSMAGSAALILAAYHPDRFIYAGSMSGFL
MLBr_02655|M.leprae_Br4923 EMPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYAASLSGFL
MAV_5183|M.avium_104 EMPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFL
MMAR_0328|M.marinum_M EMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFL
MUL_4793|M.ulcerans_Agy99 EMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFL
TH_2078|M.thermoresistible__bu ELPAYLASNYGVDRNRNAAVGLSMAGSAALVLAIYYPQQFQYAASLSGFL
MAB_1579|M.abscessus_ATCC_1997 ELPQWLGVNKGISPAANAVVGLSMAGPSALTLAIYHPQQFVYAGALSAPL
*:* :: * : .*.:****:* ::: ** ::* :* :*.::*. *
Mb1918c|M.bovis_AF2122/97 DPSQGMGPSLIGLAMGDAGGYKAADMWGPSSDP--AWERNDPTQQIPKLV
Rv1886c|M.tuberculosis_H37Rv DPSQGMGPSLIGLAMGDAGGYKAADMWGPSSDP--AWERNDPTQQIPKLV
Mflv_4459|M.gilvum_PYR-GCK NPSEGWWPGLINISMGDAGGYKANDMWGPAET-DPAWQYNDPMVQIPNLV
Mvan_1902|M.vanbaalenii_PYR-1 NPSEGWWPGLINISMGDAGGYKANDMWGPAET-DPAWQYNDPMVQIPRLV
MSMEG_2078|M.smegmatis_MC2_155 NPSEGWWPFLINISMGDAGGYKANDMWGPTEDPNSAWKRNDPMVQIPRLV
MLBr_02655|M.leprae_Br4923 NPSEGWWPTMIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLV
MAV_5183|M.avium_104 NPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLV
MMAR_0328|M.marinum_M NPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLV
MUL_4793|M.ulcerans_Agy99 NPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLV
TH_2078|M.thermoresistible__bu NLSEGWWPMLVGLAMGDAGGYDPNDMWGRTEDPNSAWKRNDPMVNIDKLV
MAB_1579|M.abscessus_ATCC_1997 HPSDQKWQ--IRVAMSDAGGFNADDMWGPDSDP--AWARNDPFLHIDQLI
. *: : ::*.*:**:.. .*** ** *** :* .*:
Mb1918c|M.bovis_AF2122/97 ANNTRLWVYCGNGTPNELG-----GANIPAEFLENFVRSSNLKFQDAYNA
Rv1886c|M.tuberculosis_H37Rv ANNTRLWVYCGNGTPNELG-----GANIPAEFLENFVRSSNLKFQDAYNA
Mflv_4459|M.gilvum_PYR-GCK ANNSRIWVYCGNGTPNELG-----GGDLPATFLEGLTIRTNRTFQDNYLA
Mvan_1902|M.vanbaalenii_PYR-1 ANNSRIWVYCGNGQPNELG-----GGDLPATFLEGLTIRTNRTFQDNYIA
MSMEG_2078|M.smegmatis_MC2_155 ANNTRIWVYCGNGQPNELG-----GGDLPATFLEGLTIRTNETFRDNYIA
MLBr_02655|M.leprae_Br4923 ANNTRIWVYCGNGAPNELG-----GDNIPAKFLESLTLSTNEIFQNTYAA
MAV_5183|M.avium_104 ANNTRIWVYCGNGTPSDLG-----GDNVPAKFLEGLTLRTNEQFQNNYAA
MMAR_0328|M.marinum_M ANNTRIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLA
MUL_4793|M.ulcerans_Agy99 ANNTRIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLA
TH_2078|M.thermoresistible__bu ANNTRIWVFCGDGTPADIGAGVPEGDNFNAKFLESFTLRTNKTFQQEYIA
MAB_1579|M.abscessus_ATCC_1997 ANNTRLWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGS
***:*:*::**.* . ::. . . .:*. . :: * : * :
Mb1918c|M.bovis_AF2122/97 AGGHNAVFNFPPNGTHSWEYWGAQLNAMKGDLQSSLGAG-----------
Rv1886c|M.tuberculosis_H37Rv AGGHNAVFNFPPNGTHSWEYWGAQLNAMKGDLQSSLGAG-----------
Mflv_4459|M.gilvum_PYR-GCK AGGKNGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLLG------------
Mvan_1902|M.vanbaalenii_PYR-1 AGGTNGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLL-------------
MSMEG_2078|M.smegmatis_MC2_155 AGGNNGVFNFPNNGTHNWAYWGRELQAMVPDLQRVLG-------------
MLBr_02655|M.leprae_Br4923 SGGRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA-------
MAV_5183|M.avium_104 AGGRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTAAPAQPAQ
MMAR_0328|M.marinum_M SGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEA
MUL_4793|M.ulcerans_Agy99 SGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEA
TH_2078|M.thermoresistible__bu AGGKNGVFNFPDAGTHSWGYWGQQLQQMKPDIQRVLGVSAA---------
MAB_1579|M.abscessus_ATCC_1997 AGGANAHFEFPKGGIHNWTYWGNQLRAMKADLVGYLTKPGTAAV------
:** *. *:** * *.* **. :* * *: *
Mb1918c|M.bovis_AF2122/97 ---------------
Rv1886c|M.tuberculosis_H37Rv ---------------
Mflv_4459|M.gilvum_PYR-GCK ---------------
Mvan_1902|M.vanbaalenii_PYR-1 ---------------
MSMEG_2078|M.smegmatis_MC2_155 ---------------
MLBr_02655|M.leprae_Br4923 ---------------
MAV_5183|M.avium_104 PAQPAQPAQPAQPAT
MMAR_0328|M.marinum_M PAAPVAPAA------
MUL_4793|M.ulcerans_Agy99 PAAPVAPAA------
TH_2078|M.thermoresistible__bu ---------------
MAB_1579|M.abscessus_ATCC_1997 ---------------