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MRLLDRIRGPWARRLGIAALAAVLLPGVVGLTGGSATAGAFSRPGLPVEYLMVPSPSMGRDIKIQFQSGG PNSPALYLLDGLRAQDDFNGWDINTQAFEWYLDSGISVIMPVGGQSSFYSNWYKPACGKSGCLTYNWETF LTQELPGWLQANRDVKPTGSAAVGLSMAGGSSLVLAAHHPGQFVWAGSMSGFLNPSEGWWPGLINISMGD AGGYKANDMWGPAETDPAWQYNDPMVQIPRLVANNSRIWVYCGNGQPNELGGGDLPATFLEGLTIRTNRT FQDNYIAAGGTNGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1902 | - | - | 100% (324) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_5645 | - | e-141 | 71.12% (322) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_3061 | - | e-128 | 65.24% (328) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1918c | fbpB | 1e-141 | 72.52% (313) | secreted antigen 85-B fbpB (85B) (antigen 85 complex B) |
| M. gilvum PYR-GCK | Mflv_4459 | - | 0.0 | 95.06% (324) | putative esterase |
| M. tuberculosis H37Rv | Rv1886c | fbpB | 1e-141 | 72.52% (313) | secreted antigen 85-B fbpB (85B) (antigen 85 complex B) |
| M. leprae Br4923 | MLBr_00097 | fbpA | 1e-133 | 67.79% (326) | antigen 85A, mycolytransferase |
| M. abscessus ATCC 19977 | MAB_1579 | - | 1e-108 | 56.10% (328) | antigen 85-B precursor |
| M. marinum M | MMAR_2777 | fbpB | 1e-137 | 70.93% (313) | secreted antigen 85-B FbpB |
| M. avium 104 | MAV_0214 | - | 1e-137 | 70.25% (326) | antigen 85-A |
| M. smegmatis MC2 155 | MSMEG_2078 | - | 1e-165 | 82.61% (322) | antigen 85-C |
| M. thermoresistible (build 8) | TH_2078 | fbpA | 1e-131 | 67.27% (330) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-136 | 68.94% (322) | secreted antigen 85-C FbpC |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1918c|M.bovis_AF2122/97 MTDVS---RKIRAWGRRLMIGTAAAVVLPGLVGLAGGAATAGAFSRPGLP
Rv1886c|M.tuberculosis_H37Rv MTDVS---RKIRAWGRRLMIGTAAAVVLPGLVGLAGGAATAGAFSRPGLP
MMAR_2777|M.marinum_M MTDVS---GKIRTWGRRLLIGAAAAITLPGLVGLAGGAPAAKAFSRPGLP
MLBr_00097|M.leprae_Br4923 MKFVDRFRGAVAGMLRRLVVEAMGVALLSALIGVVG-SAPAEAFSRPGLP
MAV_0214|M.avium_104 MTLVDRLRGAVAGMPRRLVVGAAGAALLSGLIGAVGGSATAGAFSRPGLP
Mvan_1902|M.vanbaalenii_PYR-1 MRLLDRIRG---PWARRLGIAALAAVLLPGVVGLTGGSATAGAFSRPGLP
Mflv_4459|M.gilvum_PYR-GCK MRLLDRIRG---PWARRLGIATLAALLLPGVVGLTGGSVTAGAFSRPGLP
MSMEG_2078|M.smegmatis_MC2_155 MTFIDKIRG---HWARRMTVAAVAALLLPGLVGVVGGSATAGAFSRPGLP
TH_2078|M.thermoresistible__bu MKLVAKLRGAARALPRRLTVAALAAALLPGLVGAFGGSATAGAFSRPGLP
MUL_4793|M.ulcerans_Agy99 MKFVEKLRGAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRPGLP
MAB_1579|M.abscessus_ATCC_1997 MEFLQKMRG---ATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSRPGLP
* : * : : .. *..::* * : * ********
Mb1918c|M.bovis_AF2122/97 VEYLQVPSPSMGRDIKVQFQSGGNNSPAVYLLDGLRAQDDYNGWDINTPA
Rv1886c|M.tuberculosis_H37Rv VEYLQVPSPSMGRDIKVQFQSGGNNSPAVYLLDGLRAQDDYNGWDINTPA
MMAR_2777|M.marinum_M VEYLQVPSAAMGRSIKVQFQSGGDNSPAVYLLDGLRAQDDYNGWDINTPA
MLBr_00097|M.leprae_Br4923 VEYLQVPSPSMGRDIKVQFQNGGANSPALYLLDGLRAQDDFSGWDINTTA
MAV_0214|M.avium_104 VEYLQVPSAAMGRDIKVQFQSGGANSPALYLLDGMRAQDDFNGWDINTPA
Mvan_1902|M.vanbaalenii_PYR-1 VEYLMVPSPSMGRDIKIQFQSGGPNSPALYLLDGLRAQDDFNGWDINTQA
Mflv_4459|M.gilvum_PYR-GCK VEYLMVPSPSMGRDIKVQFQSGGPNSPALYLLDGLRAQDDFNGWDINTQA
MSMEG_2078|M.smegmatis_MC2_155 VEYLMVPSPSMGRDIKVQFQSGGPGSHAVYLLDGLRAQDDFNGWDINTNA
TH_2078|M.thermoresistible__bu VEYLMVPSAAMGRDIKVQFQSGGEGSPGVYLLDGLRARDDFNGWDIETAA
MUL_4793|M.ulcerans_Agy99 VEYLQIPSAAMGRDIKVQFQGGGAHS--VYLLDGLRAQDDYNGWDINTPA
MAB_1579|M.abscessus_ATCC_1997 VEYLQVPSPAMGRDIVVEFQPGGPHA--VYLLDGQRAREDYNGWDIETTA
**** :**.:***.* ::** ** : :***** **::*:.****:* *
Mb1918c|M.bovis_AF2122/97 FEWYYQSGLSIVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTSELPQ
Rv1886c|M.tuberculosis_H37Rv FEWYYQSGLSIVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTSELPQ
MMAR_2777|M.marinum_M FEWYYQSGLSVIMPVGGQSSFYANWYQPACGKAGCSTYKWETFLTSELPE
MLBr_00097|M.leprae_Br4923 FEWYYQSGISVVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTSELPQ
MAV_0214|M.avium_104 FEWYNQSGISVAMPVGGQSSFYSDWYKPACGKAGCTTYKWETFLTSELPQ
Mvan_1902|M.vanbaalenii_PYR-1 FEWYLDSGISVIMPVGGQSSFYSNWYKPACGKSGCLTYNWETFLTQELPG
Mflv_4459|M.gilvum_PYR-GCK FEWYLDSGISVVMPVGGQSSFYSNWYKPACGKNGCLTYNWETFLTQELPA
MSMEG_2078|M.smegmatis_MC2_155 FEMFLDSGLSVVMPVGGQSSFYSDWYQPACGNNGCVTYKWETFLTSELPE
TH_2078|M.thermoresistible__bu FEWYYESGLSVIMPVGGQSSFYSDWYSPACGNNGCQTYKWETFLTQELPA
MUL_4793|M.ulcerans_Agy99 FEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTREMPA
MAB_1579|M.abscessus_ATCC_1997 FEDYYQSGISVVMPVGGQSSNYTDWYNPAKGKDGVWTYKWETFLTTELPQ
** : :**:*: ******** *::**.*: *: **:****** *:*
Mb1918c|M.bovis_AF2122/97 WLSANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSALLDPSQ
Rv1886c|M.tuberculosis_H37Rv WLSANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSALLDPSQ
MMAR_2777|M.marinum_M WLSANRSVKPTGSAAVGISMSGSSAMILAVYHPQQFVYAGSLSALLDPSQ
MLBr_00097|M.leprae_Br4923 YLQSNKQIKPTGSAAVGLSMAGLSALTLAIYHPDQFIYVGSMSGLLDPSN
MAV_0214|M.avium_104 YLSAQKQVKPTGSGVVGLSMAGSSALILAAYHPDQFVYAGSLSALLDPSQ
Mvan_1902|M.vanbaalenii_PYR-1 WLQANRDVKPTGSAAVGLSMAGGSSLVLAAHHPGQFVWAGSMSGFLNPSE
Mflv_4459|M.gilvum_PYR-GCK WLQANRDVRPTNNAAVGLSMAGGSSLVLAAHHPGQFSYAGSMSGFLNPSE
MSMEG_2078|M.smegmatis_MC2_155 WLAANRDVAATGNAAIGLSMAGSAALILAAYHPDRFIYAGSMSGFLNPSE
TH_2078|M.thermoresistible__bu YLASNYGVDRNRNAAVGLSMAGSAALVLAIYYPQQFQYAASLSGFLNLSE
MUL_4793|M.ulcerans_Agy99 WLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFLNPSE
MAB_1579|M.abscessus_ATCC_1997 WLGVNKGISPAANAVVGLSMAGPSALTLAIYHPQQFVYAGALSAPLHPSD
:* : : ...:*:**:* ::: ** ::* :* :..::*. *. *:
Mb1918c|M.bovis_AF2122/97 GMGPSLIGLAMGDAGGYKAADMWGPSSDP--AWERNDPTQQIPKLVANNT
Rv1886c|M.tuberculosis_H37Rv GMGPSLIGLAMGDAGGYKAADMWGPSSDP--AWERNDPTQQIPKLVANNT
MMAR_2777|M.marinum_M GMGPSLIGLAMGDAGGYKAGDMWGPSSDP--AWQRNDPTIQIPALVSNNT
MLBr_00097|M.leprae_Br4923 AMGPSLIGLAMGDAGGYKAADMWGPSTDP--AWKRNDPTVNVGTLIANNT
MAV_0214|M.avium_104 GMGPSLIGLAMGDAGGYKAADMWGPKEDP--AWARNDPSLQVGKLVANNT
Mvan_1902|M.vanbaalenii_PYR-1 GWWPGLINISMGDAGGYKANDMWGPAET-DPAWQYNDPMVQIPRLVANNS
Mflv_4459|M.gilvum_PYR-GCK GWWPGLINISMGDAGGYKANDMWGPAET-DPAWQYNDPMVQIPNLVANNS
MSMEG_2078|M.smegmatis_MC2_155 GWWPFLINISMGDAGGYKANDMWGPTEDPNSAWKRNDPMVQIPRLVANNT
TH_2078|M.thermoresistible__bu GWWPMLVGLAMGDAGGYDPNDMWGRTEDPNSAWKRNDPMVNIDKLVANNT
MUL_4793|M.ulcerans_Agy99 GWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLVANNT
MAB_1579|M.abscessus_ATCC_1997 QKWQ--IRVAMSDAGGFNADDMWGPDSDP--AWARNDPFLHIDQLIANNT
: ::*.*:**:.. .*** ** *** :: *::**:
Mb1918c|M.bovis_AF2122/97 RLWVYCGNGTPNELG-----GANIPAEFLENFVRSSNLKFQDAYNAAGGH
Rv1886c|M.tuberculosis_H37Rv RLWVYCGNGTPNELG-----GANIPAEFLENFVRSSNLKFQDAYNAAGGH
MMAR_2777|M.marinum_M RLWVYCGNGTPSELG-----GANLPAEFLENFVRSSNLKFQDAYNAAGGH
MLBr_00097|M.leprae_Br4923 RIWMYCGNGKPTELG-----GNNLPAKLLEGLVRTSNIKFQDGYNAGGGH
MAV_0214|M.avium_104 RIWVYCGNGKPSDLG-----GDNLPAKFLEGFVRTSNLKFQDAYNGAGGH
Mvan_1902|M.vanbaalenii_PYR-1 RIWVYCGNGQPNELG-----GGDLPATFLEGLTIRTNRTFQDNYIAAGGT
Mflv_4459|M.gilvum_PYR-GCK RIWVYCGNGTPNELG-----GGDLPATFLEGLTIRTNRTFQDNYLAAGGK
MSMEG_2078|M.smegmatis_MC2_155 RIWVYCGNGQPNELG-----GGDLPATFLEGLTIRTNETFRDNYIAAGGN
TH_2078|M.thermoresistible__bu RIWVFCGDGTPADIGAGVPEGDNFNAKFLESFTLRTNKTFQQEYIAAGGK
MUL_4793|M.ulcerans_Agy99 RIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLASGGR
MAB_1579|M.abscessus_ATCC_1997 RLWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGSAGGA
*:*::**.* . ::. : . .:*. . :: .* : * ..**
Mb1918c|M.bovis_AF2122/97 NAVFNFPPNGTHSWEYWGAQLNAMKGDLQSSLGAG---------------
Rv1886c|M.tuberculosis_H37Rv NAVFNFPPNGTHSWEYWGAQLNAMKGDLQSSLGAG---------------
MMAR_2777|M.marinum_M NAVFNFNDNGTHSWEYWGAQLNAMKGDLQASLGAA---------------
MLBr_00097|M.leprae_Br4923 NAVFNFPDSGTHSWEYWGEQLNDMKPDLQQYLGATPGA------------
MAV_0214|M.avium_104 NAVWNFDANGTHDWPYWGAQLQAMKPDLQSVLGATPGAGPATAAATNAGN
Mvan_1902|M.vanbaalenii_PYR-1 NGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLL-----------------
Mflv_4459|M.gilvum_PYR-GCK NGVFNFPNNGTHNWAYWGRELQAMKPDLQAHLLG----------------
MSMEG_2078|M.smegmatis_MC2_155 NGVFNFPNNGTHNWAYWGRELQAMVPDLQRVLG-----------------
TH_2078|M.thermoresistible__bu NGVFNFPDAGTHSWGYWGQQLQQMKPDIQRVLG---VSAA----------
MUL_4793|M.ulcerans_Agy99 NGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAPAAP
MAB_1579|M.abscessus_ATCC_1997 NAHFEFPKGGIHNWTYWGNQLRAMKADLVGYLTKPGTAAV----------
*. ::* * *.* **. :* * *: *
Mb1918c|M.bovis_AF2122/97 -----
Rv1886c|M.tuberculosis_H37Rv -----
MMAR_2777|M.marinum_M -----
MLBr_00097|M.leprae_Br4923 -----
MAV_0214|M.avium_104 GQGT-
Mvan_1902|M.vanbaalenii_PYR-1 -----
Mflv_4459|M.gilvum_PYR-GCK -----
MSMEG_2078|M.smegmatis_MC2_155 -----
TH_2078|M.thermoresistible__bu -----
MUL_4793|M.ulcerans_Agy99 VAPAA
MAB_1579|M.abscessus_ATCC_1997 -----